id subject predicate object category relation description has_attribute source uuid:2e9fd546-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2ea008cc-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:2ea032a2-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:2ea05976-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets GPCR (Prostaglandin E2 receptor EP1 subtype) DrugCentral uuid:2ea07ece-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.707']} DrugCentral uuid:2ea0a886-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (5-hydroxytryptamine receptor 3A) DrugCentral uuid:2ea0cde8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:2ea0f840-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily A member 5) DrugCentral uuid:2ea121a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:2ea121a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:2ea1520e-7972-11ec-93d9-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is blocker of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:2ea17c52-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2ea1a63c-7972-11ec-93d9-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ea1d030-7972-11ec-93d9-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ea1fa10-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ea22562-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:2ea24af6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:13 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levdobutamine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:2ea2703a-7972-11ec-93d9-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2ea299c0-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:2ea2c3d2-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2ea2ed62-7972-11ec-93d9-0242ac110002 UniProtKB:P48760 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Folylpoly-gamma-glutamate synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:2ea31710-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2ea3408c-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:2ea36a62-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:2ea393d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:2ea3bd32-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:2ea3e7c6-7972-11ec-93d9-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:25 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacitidine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ea41200-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:25 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacitidine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:2ea43712-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:2ea45c1a-7972-11ec-93d9-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:2ea48118-7972-11ec-93d9-0242ac110002 UniProtKB:Q96J66 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Transporter (ATP-binding cassette sub-family C member 11) DrugCentral uuid:2ea4a6e8-7972-11ec-93d9-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2ea4d050-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8F0 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Enzyme (Uracil phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2ea4f9d6-7972-11ec-93d9-0242ac110002 UniProtKB:O26232 biolink:molecularly_interacts_with DrugCentral:27 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azaribine targets Enzyme (Orotidine 5'-phosphate decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:2ea52370-7972-11ec-93d9-0242ac110002 UniProtKB:P03962 biolink:molecularly_interacts_with DrugCentral:27 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azaribine targets Enzyme (Orotidine 5'-phosphate decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:2ea54dc8-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:2ea5771c-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:2ea5a1b0-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:2ea5cc76-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:2ea5f8c2-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:2ea6227a-7972-11ec-93d9-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.276']} DrugCentral uuid:2ea64bf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:2ea67608-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:2ea69f70-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:35 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abarelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.49']} DrugCentral uuid:2ea6d0e4-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:2ea6d0e4-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:2ea6d0e4-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:2ea72300-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:2ea72300-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:2ea72300-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:2ea72300-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:2ea72300-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:2ea72300-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:2ea72300-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:2ea787f0-7972-11ec-93d9-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose is inhibitor of Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.697']} DrugCentral uuid:2ea7b2ca-7972-11ec-93d9-0242ac110002 UniProtKB:P04746 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose is inhibitor of Enzyme (Pancreatic alpha-amylase) DrugCentral uuid:2ea7d7f0-7972-11ec-93d9-0242ac110002 UniProtKB:P04745 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Alpha-amylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ea8014e-7972-11ec-93d9-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2ea82aca-7972-11ec-93d9-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2ea854f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:2ea87e6c-7972-11ec-93d9-0242ac110002 UniProtKB:P94451 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:2ea8a7e8-7972-11ec-93d9-0242ac110002 UniProtKB:P53051 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Oligo-1,6-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:2ea8d1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P00690 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Pancreatic alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:2ea8fb62-7972-11ec-93d9-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.609']} DrugCentral uuid:2ea924ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2ea94e3c-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2ea9789e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:2ea9a1f2-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:2ea9cb50-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2ea9f49a-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.227']} DrugCentral uuid:2eaa1e98-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:2eaa4378-7972-11ec-93d9-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:2eaa6ccc-7972-11ec-93d9-0242ac110002 UniProtKB:Q4Z710 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Unclassified (Dihydropteroate synthetase, putative) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:2eaa9620-7972-11ec-93d9-0242ac110002 UniProtKB:A0A113T0T6 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:2eaac000-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:2eaae63e-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:2eab0b5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2eab354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:48 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acenocoumarol is inhibitor of Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:2eab61e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:48 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acenocoumarol is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.114']} DrugCentral uuid:2eab8e40-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:49 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acefylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:2eabb906-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:50 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceprometazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:2eabdeae-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:2eac0820-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) DrugCentral uuid:2eac2d14-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:2eac5208-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:2eac7bf2-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:2eaca564-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:2eacced6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:2eacf834-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:2ead2282-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:2ead4bd6-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:2ead7534-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:2ead9e92-7972-11ec-93d9-0242ac110002 UniProtKB:P20292 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Cytosolic other (Arachidonate 5-lipoxygenase-activating protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:2eadc85e-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.547']} DrugCentral uuid:2eadf1a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:2eae1b10-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:2eae448c-7972-11ec-93d9-0242ac110002 UniProtKB:P02144 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Unclassified (Myoglobin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:2eae6e62-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is agonist of GPCR (Cannabinoid receptor 1) DrugCentral uuid:2eae934c-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:54 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetanilide targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:2eaebcbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9VTU8 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2, isoform A; LD26647p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:2eaee626-7972-11ec-93d9-0242ac110002 UniProtKB:Q9V396 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 1; GH09688p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:2eaf1218-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:2eaf3b9e-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2eaf651a-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2eaf8edc-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:2eafb862-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:2eafe2ec-7972-11ec-93d9-0242ac110002 UniProtKB:P29972 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Transporter (Aquaporin-1) DrugCentral uuid:2eb007cc-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:2eb031de-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:2eb05b28-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:2eb08486-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2eb0adf8-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:2eb0d8b4-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2eb103e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:2eb12d46-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:2eb156c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:2eb18084-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERQ8 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2eb1aafa-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:2eb1d46c-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:2eb1fe42-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:2eb227aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:2eb25112-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:2eb27a7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2eb2a4e6-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2eb2ce62-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2eb2f7c0-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2eb32132-7972-11ec-93d9-0242ac110002 UniProtKB:P29029 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Endochitinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:2eb34b4e-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:2eb374ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:2eb39e0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:2eb3c77c-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:2eb3f15c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:2eb41bbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:2eb44530-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:2eb46fb0-7972-11ec-93d9-0242ac110002 UniProtKB:P00921 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb4c3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2eb57de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2eb57de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2eb57de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2eb57de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2eb5d102-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:2eb5d102-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:2eb60672-7972-11ec-93d9-0242ac110002 UniProtKB:P46510 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:2eb62fd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.08']} DrugCentral uuid:2eb65bf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.56']} DrugCentral uuid:2eb68570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HVB9 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:2eb6aece-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:2eb6d976-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:2eb7036a-7972-11ec-93d9-0242ac110002 UniProtKB:O75493 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase-related protein 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:2eb730ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:57 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohexamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.639']} DrugCentral uuid:2eb730ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:57 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohexamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.639']} DrugCentral uuid:2eb76652-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:2eb797e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:2eb797e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:2eb797e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:2eb7d1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P07374 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Urease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:2eb7fb26-7972-11ec-93d9-0242ac110002 UniProtKB:Q0PXQ5 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Urease subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:2eb82574-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:59 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetophenazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:2eb84a68-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:59 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetophenazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:2eb873d0-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:2eb89d24-7972-11ec-93d9-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril is inhibitor of Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2eb8c6f0-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:2eb8f026-7972-11ec-93d9-0242ac110002 UniProtKB:P07861 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:2eb91948-7972-11ec-93d9-0242ac110002 UniProtKB:P08049 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2eb9427e-7972-11ec-93d9-0242ac110002 UniProtKB:P19621 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:2eb96c36-7972-11ec-93d9-0242ac110002 UniProtKB:P42892 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Endothelin-converting enzyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2eb99558-7972-11ec-93d9-0242ac110002 UniProtKB:P00800 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Thermolysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:2eb9be7a-7972-11ec-93d9-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:2eb9e896-7972-11ec-93d9-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:2eba146a-7972-11ec-93d9-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:2eba3d82-7972-11ec-93d9-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2eba6690-7972-11ec-93d9-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:2eba9020-7972-11ec-93d9-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:2ebaba3c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:2ebae354-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:2ebb0c9e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:2ebb37b4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2ebb6112-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:2ebb8a34-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:2ebbb374-7972-11ec-93d9-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:2ebbe02e-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:2ebc0b94-7972-11ec-93d9-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:2ebc38c6-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2ebc38c6-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2ebc7296-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:2ebc7296-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:2ebcabf8-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:2ebcabf8-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:2ebce528-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:2ebce528-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:2ebd1fac-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:2ebd1fac-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:2ebd58fa-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:2ebd58fa-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:2ebd9f86-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2ebd9f86-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2ebd9f86-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2ebd9f86-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2ebd9f86-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2ebdfa80-7972-11ec-93d9-0242ac110002 UniProtKB:H6TY12 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Nicotinic acetylcholine receptor alpha8 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:2ebe2398-7972-11ec-93d9-0242ac110002 UniProtKB:P99999 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Enzyme (Cytochrome c) DrugCentral uuid:2ebe48dc-7972-11ec-93d9-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Secreted (Vascular endothelial growth factor A) DrugCentral uuid:2ebe6db2-7972-11ec-93d9-0242ac110002 UniProtKB:P04179 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Enzyme (Superoxide dismutase [Mn], mitochondrial) DrugCentral uuid:2ebe9292-7972-11ec-93d9-0242ac110002 UniProtKB:P48637 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine is modulator of Enzyme (Glutathione synthetase) DrugCentral uuid:2ebeb77c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine is modulator of Transporter (Cystine/glutamate transporter) DrugCentral uuid:2ebef822-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:2ebef822-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:2ebef822-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:2ebef822-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:2ebef822-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:2ebef822-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:2ebef822-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:2ebef822-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:2ebf688e-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine is antagonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:2ebf8ddc-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:2ebfb2f8-7972-11ec-93d9-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2ebfdc24-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2ec005c8-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:2ec02ef4-7972-11ec-93d9-0242ac110002 UniProtKB:P60045 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Acidic phospholipase A2 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:2ec0583e-7972-11ec-93d9-0242ac110002 UniProtKB:P19440 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Gamma-glutamyltranspeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:2ec0816a-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ec0aadc-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:2ec0d3fe-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:2ec0fd34-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:2ec12656-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:2ec1532e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:76 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acipimox is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2ec17f66-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) DrugCentral uuid:2ec1a5fe-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:2ec1cf34-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) DrugCentral uuid:2ec1f464-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:2ec21d9a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.152']} DrugCentral uuid:2ec246da-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2ec27024-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase 1) DrugCentral uuid:2ec299be-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase II) DrugCentral uuid:2ec299be-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase II) DrugCentral uuid:2ec2d8f2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:2ec2d8f2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:2ec2d8f2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:2ec2d8f2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:2ec2d8f2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:2ec32a96-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:2ec35188-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:2ec37b72-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:2ec3a4b2-7972-11ec-93d9-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:2ec3ced8-7972-11ec-93d9-0242ac110002 UniProtKB:P09250 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Kinase (Thymidine kinase) DrugCentral uuid:2ec3f3d6-7972-11ec-93d9-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:2ec41cf8-7972-11ec-93d9-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:2ec446c4-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:2ec46bb8-7972-11ec-93d9-0242ac110002 UniProtKB:P09252 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:2ec490a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Kinase (Thymidine kinase) DrugCentral uuid:2ec4b58c-7972-11ec-93d9-0242ac110002 UniProtKB:P04407 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Kinase (Thymidine kinase) DrugCentral uuid:2ec4db84-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2ec505aa-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:2ec52f1c-7972-11ec-93d9-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:2ec55956-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:2ec5830e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil is inhibitor of Polyprotein (Protein P) DrugCentral uuid:2ec5a7f8-7972-11ec-93d9-0242ac110002 UniProtKB:P54098 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil targets Enzyme (DNA polymerase subunit gamma-1) DrugCentral uuid:2ec5ccf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:2ec5f622-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:2ec62bb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:2ec62bb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:2ec62bb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:2ec62bb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:2ec67926-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:2ec6a266-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.509']} DrugCentral uuid:2ec6cda4-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:2ec6f748-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:2ec7206a-7972-11ec-93d9-0242ac110002 UniProtKB:P55263 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Adenosine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ec74964-7972-11ec-93d9-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:2ec772ea-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.29']} DrugCentral uuid:2ec79c20-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2ec7c560-7972-11ec-93d9-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2ec7ee96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9TVW2 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Adenosine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:2ec81880-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:2ec8418e-7972-11ec-93d9-0242ac110002 UniProtKB:P23526 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Adenosylhomocysteinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.796']} DrugCentral uuid:2ec86eca-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:2ec86eca-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:2ec8a61a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BTU6 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is inhibitor of Kinase (Phosphatidylinositol 4-kinase type 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2ec8cf5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCG2 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is inhibitor of Kinase (Phosphatidylinositol 4-kinase type 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2ec8f89a-7972-11ec-93d9-0242ac110002 UniProtKB:P04406 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Glyceraldehyde-3-phosphate dehydrogenase liver) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:2ec92ed2-7972-11ec-93d9-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:2ec92ed2-7972-11ec-93d9-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:2ec92ed2-7972-11ec-93d9-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:2ec92ed2-7972-11ec-93d9-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:2ec97cd4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TEK3 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Histone-lysine N-methyltransferase, H3 lysine-79 specific) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:2ec9a5f6-7972-11ec-93d9-0242ac110002 UniProtKB:P49652 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:2ec9cfc2-7972-11ec-93d9-0242ac110002 UniProtKB:P51575 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Ion channel (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:2ec9f970-7972-11ec-93d9-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:2eca23dc-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2eca4d3a-7972-11ec-93d9-0242ac110002 UniProtKB:P47900 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:2eca77a6-7972-11ec-93d9-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2ecaa0f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:2ecaca1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:2ecaf352-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2ecb1cec-7972-11ec-93d9-0242ac110002 UniProtKB:P41148 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Membrane other (Endoplasmin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:2ecb462c-7972-11ec-93d9-0242ac110002 UniProtKB:P49137 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (MAP kinase-activated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:2ecb6f58-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:2ecb98ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2ecbc26e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:2ecbeb86-7972-11ec-93d9-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.836']} DrugCentral uuid:2ecc14ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q12931 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock protein 75 kDa, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:2ecc3f5a-7972-11ec-93d9-0242ac110002 UniProtKB:P29410 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Adenylate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:2ecc6b88-7972-11ec-93d9-0242ac110002 UniProtKB:P11142 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock cognate 71 kDa protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:2ecc950e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMV8 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock 70 kDa protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:2eccbe58-7972-11ec-93d9-0242ac110002 UniProtKB:Q7TN37 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:2ecce8ec-7972-11ec-93d9-0242ac110002 UniProtKB:P49653 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:2ecd1218-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJX6 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ecd3b3a-7972-11ec-93d9-0242ac110002 UniProtKB:O35811 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2ecd6470-7972-11ec-93d9-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2ecd8e32-7972-11ec-93d9-0242ac110002 UniProtKB:P51579 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ecdb74a-7972-11ec-93d9-0242ac110002 UniProtKB:P51578 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ecde08a-7972-11ec-93d9-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2ece09de-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2ece3440-7972-11ec-93d9-0242ac110002 UniProtKB:P09467 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Fructose-1,6-bisphosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:2ece5d76-7972-11ec-93d9-0242ac110002 UniProtKB:P00636 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Fructose-1,6-bisphosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2ece86b6-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:2eceb050-7972-11ec-93d9-0242ac110002 UniProtKB:O94759 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Ion channel (Transient receptor potential cation channel subfamily M member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:2eced990-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:2ecf02bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:2ecf2ff8-7972-11ec-93d9-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:2ecf2ff8-7972-11ec-93d9-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:2ecf661c-7972-11ec-93d9-0242ac110002 UniProtKB:P00338 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (L-lactate dehydrogenase A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.19']} DrugCentral uuid:2ecf8f52-7972-11ec-93d9-0242ac110002 UniProtKB:P0A9J4 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Ketopantoate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.2']} DrugCentral uuid:2ecfb8a6-7972-11ec-93d9-0242ac110002 UniProtKB:P29410 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Kinase (Adenylate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:2ecfe42a-7972-11ec-93d9-0242ac110002 UniProtKB:O43598 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:2ed010bc-7972-11ec-93d9-0242ac110002 UniProtKB:O35820 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:2ed03a10-7972-11ec-93d9-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam targets Transporter (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed09212-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:2ed1362c-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2ed16ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:2ed16ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:2ed16ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:2ed16ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:2ed16ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:2ed1c984-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2ed1f2ba-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:2ed22000-7972-11ec-93d9-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:2ed22000-7972-11ec-93d9-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:2ed25dea-7972-11ec-93d9-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:2ed25dea-7972-11ec-93d9-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:2ed25dea-7972-11ec-93d9-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:2ed29f58-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:2ed2c8de-7972-11ec-93d9-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:2ed2f2aa-7972-11ec-93d9-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:2ed31c1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:2ed34110-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ed36b2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:2ed395fc-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:2ed3bf5a-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alacepril is inhibitor of Enzyme (Angiotensin-converting enzyme) DrugCentral uuid:2ed3e84a-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:2ed3e84a-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:2ed41d38-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:2ed41d38-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:2ed44d44-7972-11ec-93d9-0242ac110002 UniProtKB:P50719 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole targets Structural (Tubulin alpha chain) DrugCentral uuid:2ed479fe-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed479fe-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed479fe-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed4cb98-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed4cb98-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed4cb98-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed4cb98-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed4cb98-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed4cb98-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed4cb98-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:2ed52f48-7972-11ec-93d9-0242ac110002 UniProtKB:P50719 biolink:molecularly_interacts_with DrugCentral:104 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole sulfoxide targets Structural (Tubulin alpha chain) DrugCentral uuid:2ed55432-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.613']} DrugCentral uuid:2ed58056-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:2ed5a9a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.94']} DrugCentral uuid:2ed5d2ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:2ed5fcf2-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:2ed621c8-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclofenac targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:2ed646c6-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:2ed67010-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.9']} DrugCentral uuid:2ed699fa-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:2ed6c33a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2ed6ec8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.721']} DrugCentral uuid:2ed7174a-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.959']} DrugCentral uuid:2ed741ac-7972-11ec-93d9-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2ed77258-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:2ed77258-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:2ed77258-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:2ed7aff2-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.347']} DrugCentral uuid:2ed7aff2-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.347']} DrugCentral uuid:2ed7e5d0-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:2ed80ee8-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:2ed83828-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:2ed86154-7972-11ec-93d9-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.37']} DrugCentral uuid:2ed88aee-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:2ed8b550-7972-11ec-93d9-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:2ed8de68-7972-11ec-93d9-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Protein farnesyltransferase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:2ed90816-7972-11ec-93d9-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:2ed93336-7972-11ec-93d9-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:2ed95c58-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:2ed98584-7972-11ec-93d9-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:2ed9af64-7972-11ec-93d9-0242ac110002 UniProtKB:Q932Y6 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:2ed9d89a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WUK0 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine is inhibitor of Enzyme (Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.97']} DrugCentral uuid:2eda01bc-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:2eda2aca-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.951']} DrugCentral uuid:2eda545a-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:2eda7d86-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:2edab206-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:2edab206-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:2edab206-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:2edab206-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:2edb0490-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:2edb2e66-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:2edb57c4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:2edb81a4-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:2edbaac6-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:2edbd3de-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:2edbfd14-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:2edc269a-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.61']} DrugCentral uuid:2edc4fbc-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.678']} DrugCentral uuid:2edc7906-7972-11ec-93d9-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren is inhibitor of Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:2edca200-7972-11ec-93d9-0242ac110002 UniProtKB:Q9TSZ1 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2edcccda-7972-11ec-93d9-0242ac110002 UniProtKB:Q6DLS0 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2edcf66a-7972-11ec-93d9-0242ac110002 UniProtKB:P08424 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2edd1f6e-7972-11ec-93d9-0242ac110002 UniProtKB:P06281 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:2edd4872-7972-11ec-93d9-0242ac110002 UniProtKB:Q7M3D2 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2edd7252-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:2edd9b6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q6DLW5 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:2eddc496-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:2eddee3a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2ede175c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2ede4088-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:2ede6af4-7972-11ec-93d9-0242ac110002 UniProtKB:P00492 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) DrugCentral uuid:2ede9128-7972-11ec-93d9-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:2edeba90-7972-11ec-93d9-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:2edee4de-7972-11ec-93d9-0242ac110002 UniProtKB:Q9FBI2 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Unclassified (Shiga toxin subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:2edf0e14-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:2edf3812-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2edf613e-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2edf8a74-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:2edfb396-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:2edfdd30-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:2ee00670-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.218']} DrugCentral uuid:2ee02f7e-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfacalcidol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:2ee058a0-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfacalcidol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:2ee080d2-7972-11ec-93d9-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Transporter (Sodium- and chloride-dependent GABA transporter 1) DrugCentral uuid:2ee0ad3c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:2ee0ad3c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:2ee0ad3c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee128d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2ee20fc4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2ee20fc4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2ee20fc4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2ee25470-7972-11ec-93d9-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:2ee27e32-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:2ee2a89e-7972-11ec-93d9-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee30ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ee3eab0-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:2ee414b8-7972-11ec-93d9-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Unclassified (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:2ee43e02-7972-11ec-93d9-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem is partial agonist of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) DrugCentral uuid:2ee462d8-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.85']} DrugCentral uuid:2ee48bf0-7972-11ec-93d9-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.457']} DrugCentral uuid:2ee4b62a-7972-11ec-93d9-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:2ee4df38-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.61']} DrugCentral uuid:2ee51034-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:2ee51034-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:2ee51034-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:2ee559c2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:2ee559c2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:2ee559c2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:2ee5a2c4-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:2ee5a2c4-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:2ee5a2c4-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:2ee5ed9c-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:2ee5ed9c-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:2ee5ed9c-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:2ee62ece-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:2ee657f0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:2ee68298-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.86']} DrugCentral uuid:2ee6acaa-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:2ee6d5cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q02769 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:2ee6fed0-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:2ee72892-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:2ee751d2-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.678']} DrugCentral uuid:2ee77b30-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.658']} DrugCentral uuid:2ee7a45c-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:2ee7d062-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2ee7f934-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2ee8224c-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:2ee84c22-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:2ee8754e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2ee89e52-7972-11ec-93d9-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:2ee8c774-7972-11ec-93d9-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:2ee8f140-7972-11ec-93d9-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:2ee91a76-7972-11ec-93d9-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:2ee943b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:2ee96cd8-7972-11ec-93d9-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:2ee996c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2ee9bfda-7972-11ec-93d9-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2ee9e8e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2eea1214-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2eea3b86-7972-11ec-93d9-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2eea64b2-7972-11ec-93d9-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.35']} DrugCentral uuid:2eea8dc0-7972-11ec-93d9-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2eeab7dc-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 altretamine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:2eeae194-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:2eeb0ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2eeb346e-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2eeb5eda-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:2eeb882e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:2eebb164-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:2eebdaa4-7972-11ec-93d9-0242ac110002 UniProtKB:P63231 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is inhibitor of Ion channel (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:2eec1b86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:2eec1b86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:2eec1b86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:2eec1b86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:2eec1b86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:2eec1b86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:2eec1b86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:2eec8e7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q20MD5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:2eecb7e4-7972-11ec-93d9-0242ac110002 UniProtKB:P05778 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:2eece106-7972-11ec-93d9-0242ac110002 UniProtKB:P0DOF8 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:2eed0a0a-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:2eed2f94-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.34']} DrugCentral uuid:2eed58b6-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:2eed81ce-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.744']} DrugCentral uuid:2eedab04-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.254']} DrugCentral uuid:2eedd494-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:2eedf974-7972-11ec-93d9-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:2eee2296-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amcinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:2eee4ffa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:2eee4ffa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:2eee4ffa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:2eee9960-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:2eee9960-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:2eee9960-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:2eeedab0-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifostine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:2eef049a-7972-11ec-93d9-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifostine targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) DrugCentral uuid:2eef295c-7972-11ec-93d9-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amikacin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.201']} DrugCentral uuid:2eef5292-7972-11ec-93d9-0242ac110002 UniProtKB:P37088 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Amiloride-sensitive sodium channel subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:2eef7bb4-7972-11ec-93d9-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:2eefa58a-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:2eefceac-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.408']} DrugCentral uuid:2eeff7ce-7972-11ec-93d9-0242ac110002 UniProtKB:P19634 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:2ef020fa-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:2ef04a80-7972-11ec-93d9-0242ac110002 UniProtKB:Q16515 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Acid-sensing ion channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:2ef07384-7972-11ec-93d9-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2ef09c88-7972-11ec-93d9-0242ac110002 UniProtKB:O08590 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:2ef0c636-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:2ef0fa3e-7972-11ec-93d9-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2ef0fa3e-7972-11ec-93d9-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2ef0fa3e-7972-11ec-93d9-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2ef13bb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9W6Q1 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:2ef16604-7972-11ec-93d9-0242ac110002 UniProtKB:Q14940 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is inhibitor of Transporter (Sodium/hydrogen exchanger 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:2ef18fda-7972-11ec-93d9-0242ac110002 UniProtKB:P26431 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is inhibitor of Transporter (Sodium/hydrogen exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:2ef1b9e2-7972-11ec-93d9-0242ac110002 UniProtKB:P50482 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:2ef1e2fa-7972-11ec-93d9-0242ac110002 UniProtKB:P06869 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:2ef20c3a-7972-11ec-93d9-0242ac110002 UniProtKB:P55926 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:2ef235b6-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:2ef25ee2-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:2ef28840-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:2ef2b2c0-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amineptine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2ef2dc32-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminocaproic acid is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:2ef30568-7972-11ec-93d9-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminocaproic acid is inhibitor of Enzyme (Tissue-type plasminogen activator) DrugCentral uuid:2ef32a48-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:2ef35400-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:2ef37d22-7972-11ec-93d9-0242ac110002 UniProtKB:P05108 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide is inhibitor of Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) DrugCentral uuid:2ef3a20c-7972-11ec-93d9-0242ac110002 UniProtKB:P22443 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:2ef3cb06-7972-11ec-93d9-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:2ef3f478-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminohippuric acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:2ef41dae-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminohippuric acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:2ef446e4-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:2ef46bd8-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:2ef492d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:2ef4bc82-7972-11ec-93d9-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopicoline is inhibitor of Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2ef4e5ae-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:2ef50ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:2ef53892-7972-11ec-93d9-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2ef561e6-7972-11ec-93d9-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:2ef58b08-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:2ef5b434-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2ef5dec8-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.112']} DrugCentral uuid:2ef6081c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:2ef63152-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.177']} DrugCentral uuid:2ef65bc8-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2ef6856c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2ef6ae8e-7972-11ec-93d9-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:2ef6d7a6-7972-11ec-93d9-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:2ef70230-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2ef72b52-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:2ef755aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:2ef77ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2ef7a870-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.912']} DrugCentral uuid:2ef7d19c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.647']} DrugCentral uuid:2ef7fabe-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.989']} DrugCentral uuid:2ef823f4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.231']} DrugCentral uuid:2ef84e2e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.674']} DrugCentral uuid:2ef87746-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.045']} DrugCentral uuid:2ef8a072-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:2ef8ca66-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:2ef8f37e-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.984']} DrugCentral uuid:2ef91c96-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:2ef945e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.743']} DrugCentral uuid:2ef9709c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.168']} DrugCentral uuid:2ef999c8-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.296']} DrugCentral uuid:2ef9c2d6-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.968']} DrugCentral uuid:2ef9ecf2-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.498']} DrugCentral uuid:2efa17b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.701']} DrugCentral uuid:2efa40d0-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.004']} DrugCentral uuid:2efa69fc-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.207']} DrugCentral uuid:2efa931e-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.176']} DrugCentral uuid:2efabcfe-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.549']} DrugCentral uuid:2efae616-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:2efb0f10-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.284']} DrugCentral uuid:2efb38b4-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.791']} DrugCentral uuid:2efb61e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:2efb8b0c-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.088']} DrugCentral uuid:2efbb438-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.039']} DrugCentral uuid:2efbded6-7972-11ec-93d9-0242ac110002 UniProtKB:P37268 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:2efc083e-7972-11ec-93d9-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.368']} DrugCentral uuid:2efc3174-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.191']} DrugCentral uuid:2efc5a8c-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:2efc846c-7972-11ec-93d9-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:2efcad70-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.347']} DrugCentral uuid:2efcd69c-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2efd0054-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.407']} DrugCentral uuid:2efd29e4-7972-11ec-93d9-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.115']} DrugCentral uuid:2efd531a-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.879']} DrugCentral uuid:2efd7dc2-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:2efda7c0-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.967']} DrugCentral uuid:2efdd100-7972-11ec-93d9-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.943']} DrugCentral uuid:2efdfb30-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.932']} DrugCentral uuid:2efe2452-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:2efe4e14-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2efe7718-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:2efea01c-7972-11ec-93d9-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2efec92a-7972-11ec-93d9-0242ac110002 UniProtKB:O75151 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase PHF2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:2efef2ba-7972-11ec-93d9-0242ac110002 UniProtKB:P29375 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:2eff1be6-7972-11ec-93d9-0242ac110002 UniProtKB:Q6ZMT4 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:2eff44ea-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.953']} DrugCentral uuid:2eff6e0c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.081']} DrugCentral uuid:2eff9a12-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:2effc38e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.382']} DrugCentral uuid:2effecb0-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:2f0015d2-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.758']} DrugCentral uuid:2f003fbc-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:2f0068de-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:2f009200-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.625']} DrugCentral uuid:2f00bb90-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2f00e4da-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:2f010dfc-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:2f01373c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:2f01623e-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:2f018bb0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:2f01b4e6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:2f01de12-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:2f0208e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2f02322c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.367']} DrugCentral uuid:2f025b62-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.456']} DrugCentral uuid:2f028498-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:2f02ae28-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2f02d75e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2f030080-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2f032a7e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:2f035396-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2f037cc2-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:2f03a724-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:2f03d172-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.686']} DrugCentral uuid:2f03fa94-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:2f0423c0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:2f044cd8-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:2f047654-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:2f049f76-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.83']} DrugCentral uuid:2f04c898-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2f04f1b0-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:2f051cc6-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:2f0545de-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2f056eec-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.585']} DrugCentral uuid:2f0598a4-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.066']} DrugCentral uuid:2f05c1c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:2f05ead4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f06150e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:2f063e8a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:2f0667b6-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f0690e2-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:2f06ba0e-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2f06e40c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:2f070d38-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.771']} DrugCentral uuid:2f073682-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:2f075f9a-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2f078966-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:2f07b288-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2f07dbb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2f0804d6-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2f082e5c-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2f08577e-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2f0880b4-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:2f08aa9e-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f08d3ca-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.854']} DrugCentral uuid:2f090c32-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f090c32-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f090c32-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f090c32-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f090c32-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f096790-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:2f09909e-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptylinoxide targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2f09ba9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f09e418-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f0a0d30-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2f0a41e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:2f0a41e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:2f0a41e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:2f0a41e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:2f0a883c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.646']} DrugCentral uuid:2f0ab3ca-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.871']} DrugCentral uuid:2f0add82-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:2f0b06e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:2f0b305c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.583']} DrugCentral uuid:2f0b599c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.358']} DrugCentral uuid:2f0b82aa-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f0babfe-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:2f0bd5b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f0bff0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:2f0c23f4-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:2f0c48de-7972-11ec-93d9-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f0c7372-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2f0c9cb2-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.507']} DrugCentral uuid:2f0cc5de-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2f0cef8c-7972-11ec-93d9-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2f0d18c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:2f0d41da-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:2f0d6b1a-7972-11ec-93d9-0242ac110002 UniProtKB:P50135 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Enzyme (Histamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:2f0d95cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y251 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Enzyme (Heparanase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.28']} DrugCentral uuid:2f0dbeee-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2f0de82e-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:2f0e1150-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:2f0e3ca2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:2f0e65d8-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:2f0e8ac2-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.469']} DrugCentral uuid:2f0eb3f8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:2f0ee026-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:2f0f0970-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.75']} DrugCentral uuid:2f0f32a6-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.182']} DrugCentral uuid:2f0f5c4a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2f0f8580-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f0faec0-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2f0fd80a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.593']} DrugCentral uuid:2f10021c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.734']} DrugCentral uuid:2f102b5c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:2f10547e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.542']} DrugCentral uuid:2f107db4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:2f10a73a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.423']} DrugCentral uuid:2f10d0e8-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.616']} DrugCentral uuid:2f10fa28-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.211']} DrugCentral uuid:2f112368-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.336']} DrugCentral uuid:2f114d02-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.365']} DrugCentral uuid:2f117624-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2f119f46-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:2f11c96c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.842']} DrugCentral uuid:2f11f41e-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:2f121d4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y345 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Sodium- and chloride-dependent glycine transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.036']} DrugCentral uuid:2f124662-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:2f126fde-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:2f1298d8-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:2f12c218-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2f12eb44-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2f1314e8-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:2f1345c6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2f1345c6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2f1345c6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2f13802c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:2f13aad4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:2f13d43c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:2f13fd40-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2f143904-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f143904-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f143904-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f143904-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f143904-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f143904-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f143904-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f149f20-7972-11ec-93d9-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amperozide targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:2f14c824-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amperozide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:2f14f1aa-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:2f15166c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.753']} DrugCentral uuid:2f153fac-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:2f15657c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:2f158b6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:2f15b4b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:2f15d994-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:2f1602ac-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:2f162c96-7972-11ec-93d9-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f1655a4-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f167ed0-7972-11ec-93d9-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:2f16a7d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17029c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f17d83e-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2f17d83e-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2f17d83e-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2f17d83e-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2f182f46-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:2f182f46-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:2f182f46-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:2f187280-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:2f189bfc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2f18c0d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.09']} DrugCentral uuid:2f18e9fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:2f192bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f192bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f192bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f192bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f192bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f192bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f192bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f19991c-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f19c31a-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:2f19e7dc-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.172']} DrugCentral uuid:2f1a10fe-7972-11ec-93d9-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:2f1a3a02-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:2f1a6388-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.44']} DrugCentral uuid:2f1a8cb4-7972-11ec-93d9-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:2f1ab5f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:2f1adf20-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:2f1b0aae-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:2f1b33d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:2f1b686e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:2f1b686e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:2f1b686e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:2f1b686e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:2f1bb7a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:2f1be0d2-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2f1c09f4-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2f1c3366-7972-11ec-93d9-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase I, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:2f1c5c60-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:2f1c856e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:2f1cae7c-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2f1cdc6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:2f1cdc6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:2f1d1196-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagrelide is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:2f1d3ab8-7972-11ec-93d9-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagrelide targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:2f1d6484-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anastrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:2f1d8edc-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androisoxazole targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:2f1db39e-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:2f1ddcb6-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:2f1e06e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:2f1e2ff4-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:2f1e5952-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.17']} DrugCentral uuid:2f1e827e-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:2f1eac68-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2f1ed576-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:2f1eff2e-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:2f1f2954-7972-11ec-93d9-0242ac110002 UniProtKB:P37058 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:2f1f52f8-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2f1f7c10-7972-11ec-93d9-0242ac110002 UniProtKB:O54939 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:2f1fa50a-7972-11ec-93d9-0242ac110002 UniProtKB:P05121 biolink:molecularly_interacts_with DrugCentral:217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anecortave targets Secreted (Plasminogen activator inhibitor 1) DrugCentral uuid:2f1fc9c2-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:2f1feef2-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:2f2013b4-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:2f20386c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:2f205d24-7972-11ec-93d9-0242ac110002 UniProtKB:P68371 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Structural (Tubulin beta-4B chain) DrugCentral uuid:2f208312-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anileridine is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:2f20a7f2-7972-11ec-93d9-0242ac110002 UniProtKB:P38435 biolink:molecularly_interacts_with DrugCentral:222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anisindione is inhibitor of Enzyme (Vitamin K-dependent gamma-carboxylase) DrugCentral uuid:2f20ccaa-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anisindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:2f20f5e0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octatropine methylbromide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:2f211b42-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octatropine methylbromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:2f21402c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 antazoline is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:2f216516-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 antazoline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:2f218e74-7972-11ec-93d9-0242ac110002 UniProtKB:O75342 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Arachidonate 12-lipoxygenase, 12R-type) DrugCentral uuid:2f21b39a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BEG3 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:2f21dc94-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:2f220610-7972-11ec-93d9-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:2f222f6e-7972-11ec-93d9-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:2f225962-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:2f2282c0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:2f22abf6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:2f22d540-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:2f22ff34-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:2f23287e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:2f2352e0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2f237d60-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2f23a6aa-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f23cff4-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:2f23f916-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2f242378-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:2f244cea-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:2f2476ac-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2f249fec-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:2f24c990-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:2f24f2d0-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:2f251bfc-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:2f254514-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:2f256ea4-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:2f2597d0-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:2f25c0fc-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:2f25ea28-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:2f261598-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2f263eba-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:2f2667f0-7972-11ec-93d9-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:2f2691a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2f26bac0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f26ef4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f26ef4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f26ef4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f26ef4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f276f4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:2f2840fc-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f2840fc-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f2840fc-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f2886c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2f2886c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2f28cb4e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2f28cb4e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2f28cb4e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2f28cb4e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2f28cb4e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2f292cce-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:2f292cce-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:2f292cce-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:2f296f7c-7972-11ec-93d9-0242ac110002 UniProtKB:P34949 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Enzyme (Mannose-6-phosphate isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:2f29997a-7972-11ec-93d9-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2f29c2ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q00987 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Nuclear other (E3 ubiquitin-protein ligase Mdm2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:2f29ec0e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:2f2a1576-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.938']} DrugCentral uuid:2f2a3f2e-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f2a6864-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:2f2a9942-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:2f2a9942-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:2f2a9942-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:2f2adb14-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:2f2affe0-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:2f2b290c-7972-11ec-93d9-0242ac110002 UniProtKB:P29371 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets GPCR (Neuromedin-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:2f2b52b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q5DUB1 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:2f2b7cae-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:2f2ba170-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:2f2bc63c-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.757']} DrugCentral uuid:2f2bef4a-7972-11ec-93d9-0242ac110002 UniProtKB:P25786 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Enzyme (Proteasome subunit alpha type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:2f2c18c6-7972-11ec-93d9-0242ac110002 UniProtKB:P32418 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Transporter (Sodium/calcium exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:2f2c41de-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.359']} DrugCentral uuid:2f2c72c6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:2f2c72c6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:2f2c72c6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:2f2cba2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aranidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:2f2cba2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aranidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:2f2cea80-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutamine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:2f2d0f56-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:2f2d386e-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:2f2d64ba-7972-11ec-93d9-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:2f2d8e36-7972-11ec-93d9-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:2f2db76c-7972-11ec-93d9-0242ac110002 UniProtKB:P00735 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:2f2de0f2-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.851']} DrugCentral uuid:2f2e0a14-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:2f2e3340-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:2f2e5c8a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:2f2e8642-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.131']} DrugCentral uuid:2f2eaf78-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:2f2ed8a4-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:2f2f01a8-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:2f2f2cbe-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:2f2f55fe-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:2f2f7f20-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:2f2fa842-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:2f2fd1c8-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:2f2ffaea-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:2f3023f8-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:2f304d2e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.991']} DrugCentral uuid:2f3076e6-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:2f309ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.681']} DrugCentral uuid:2f30c93e-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:2f30f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.169']} DrugCentral uuid:2f311e16-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.455']} DrugCentral uuid:2f31472e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:2f31703c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:2f3199cc-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.633']} DrugCentral uuid:2f31c2d0-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:2f31ebf2-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f321514-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.421']} DrugCentral uuid:2f323ee0-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:2f3267d0-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:2f32921e-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.202']} DrugCentral uuid:2f32bb36-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.463']} DrugCentral uuid:2f32e52a-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:2f330e4c-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:2f333782-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2f336112-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2f338b10-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:2f33b432-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:2f33dd36-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:2f340702-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2f34302e-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2f345946-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2f34824a-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:2f34acac-7972-11ec-93d9-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f34d5e2-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:2f34ff0e-7972-11ec-93d9-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f35293e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:2f3552d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arsenic trioxide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:2f357c04-7972-11ec-93d9-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arsenic trioxide is inhibitor of Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:2f35a0d0-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.312']} DrugCentral uuid:2f35c9fc-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.998']} DrugCentral uuid:2f35f3c8-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:2f361cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:2f364620-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:2f36703c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.741']} DrugCentral uuid:2f369a1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.025']} DrugCentral uuid:2f36c334-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:2f36ec42-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.481']} DrugCentral uuid:2f3715aa-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:2f373ec2-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:2f3767e4-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.865']} DrugCentral uuid:2f37911a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.359']} DrugCentral uuid:2f37bb04-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.253']} DrugCentral uuid:2f37e426-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.126']} DrugCentral uuid:2f380d84-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.027']} DrugCentral uuid:2f3836a6-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.819']} DrugCentral uuid:2f3860b8-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:2f388b1a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:2f38b450-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:2f38ddf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:2f39070c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:2f393132-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2f395a5e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:2f3984a2-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:2f39adba-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.297']} DrugCentral uuid:2f39d6dc-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.219']} DrugCentral uuid:2f39fffe-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:2f3a2ba0-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:2f3a5526-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.784']} DrugCentral uuid:2f3a7e20-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.671']} DrugCentral uuid:2f3aa74c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:2f3ad0c8-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:2f3af9ea-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.577']} DrugCentral uuid:2f3b2316-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:2f3b47c4-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:2f3b792e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f3b792e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f3b792e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f3bba42-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:2f3be350-7972-11ec-93d9-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:2f3c0e48-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.218']} DrugCentral uuid:2f3c374c-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.065']} DrugCentral uuid:2f3c606e-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.701']} DrugCentral uuid:2f3c89ea-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.546']} DrugCentral uuid:2f3cb2ee-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.883']} DrugCentral uuid:2f3cdbde-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:2f3d04f6-7972-11ec-93d9-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2f3d2f94-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:2f3d58c0-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:2f3d81d8-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:2f3daafa-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.673']} DrugCentral uuid:2f3dd552-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.868']} DrugCentral uuid:2f3dfe7e-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.733']} DrugCentral uuid:2f3e278c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:2f3e5090-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:2f3e7b38-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:2f3ea81a-7972-11ec-93d9-0242ac110002 UniProtKB:P49355 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2f3ea81a-7972-11ec-93d9-0242ac110002 UniProtKB:P49355 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2f3edd58-7972-11ec-93d9-0242ac110002 UniProtKB:O75530 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Unclassified (Polycomb protein EED) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:2f3f0724-7972-11ec-93d9-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2f3f306e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:2f3f59a4-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.58']} DrugCentral uuid:2f3f8276-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asulacrine targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:2f3fa97c-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.629']} DrugCentral uuid:2f3fd28a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:2f3ffc24-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.921']} DrugCentral uuid:2f402514-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.921']} DrugCentral uuid:2f404e90-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.575']} DrugCentral uuid:2f4077bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:2f40a0e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2f40ca6e-7972-11ec-93d9-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:2f40f390-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2f411c94-7972-11ec-93d9-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.27']} DrugCentral uuid:2f4146ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.12']} DrugCentral uuid:2f417144-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f419cbe-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:2f41c5d6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:2f41eec6-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:2f4218d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.93']} DrugCentral uuid:2f424204-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:2f426b62-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:2f4294ac-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:2f42be82-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.69']} DrugCentral uuid:2f42e7a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.97']} DrugCentral uuid:2f4310bc-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2f4339f2-7972-11ec-93d9-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.282']} DrugCentral uuid:2f4363be-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:2f438cc2-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:2f43b5f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:2f43df6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2f440c60-7972-11ec-93d9-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.478']} DrugCentral uuid:2f440c60-7972-11ec-93d9-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.478']} DrugCentral uuid:2f44454a-7972-11ec-93d9-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:2f44454a-7972-11ec-93d9-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:2f447c5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13118 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Nuclear other (Krueppel-like factor 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:2f44a576-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:2f44ca2e-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:2f44f346-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:2f451eb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:2f4547e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2f4570e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:2f4599fe-7972-11ec-93d9-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:2f45c348-7972-11ec-93d9-0242ac110002 UniProtKB:Q1W675 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:2f45ec38-7972-11ec-93d9-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:2f46153c-7972-11ec-93d9-0242ac110002 UniProtKB:P43264 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial) DrugCentral uuid:2f463a8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q02768 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone is inhibitor of Enzyme (Cytochrome b) DrugCentral uuid:2f465fec-7972-11ec-93d9-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:2f468904-7972-11ec-93d9-0242ac110002 UniProtKB:Q54A96 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:2f46b230-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:2f46d706-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:2f470320-7972-11ec-93d9-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:2f47341c-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:2f47341c-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:2f47341c-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:2f477580-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:2f479f10-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2f47c832-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:2f47f14a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:2f481a76-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:2f48441a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.907']} DrugCentral uuid:2f486d50-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:2f489672-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.97']} DrugCentral uuid:2f48c098-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:2f48ea96-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:2f4913a4-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:2f493cbc-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:2f496660-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:2f498f5a-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:2f49b89a-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.59']} DrugCentral uuid:2f49e1b2-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:2f4a0b6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:2f4a35c2-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:2f4a5ef8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:2f4a8810-7972-11ec-93d9-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:2f4ab222-7972-11ec-93d9-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:2f4adb3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.99']} DrugCentral uuid:2f4b048e-7972-11ec-93d9-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:2f4b3d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:2f4b3d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:2f4b3d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:2f4b3d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:2f4b3d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:2f4b96a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.99']} DrugCentral uuid:2f4bc81a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2f4bc81a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2f4bc81a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2f4c1180-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:2f4c1180-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:2f4c1180-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:2f4c53ca-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapropazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:2f4c7b20-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapropazone targets Enzyme (Xanthine dehydrogenase/oxidase) DrugCentral uuid:2f4ca078-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azasetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.268']} DrugCentral uuid:2f4cc99a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azatadine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:2f4cee52-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azatadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:2f4d17c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:2f4d3c90-7972-11ec-93d9-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:2f4d615c-7972-11ec-93d9-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:2f4d863c-7972-11ec-93d9-0242ac110002 UniProtKB:P63000 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Enzyme (Ras-related C3 botulinum toxin substrate 1) DrugCentral uuid:2f4dab6c-7972-11ec-93d9-0242ac110002 UniProtKB:P51580 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Enzyme (Thiopurine S-methyltransferase) DrugCentral uuid:2f4dd024-7972-11ec-93d9-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelaic acid targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) DrugCentral uuid:2f4df4dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:2f4e1dea-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:2f4e4414-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2f4e6f84-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2f4e989c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f4ec1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.168']} DrugCentral uuid:2f4eeb9e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:2f4f14c0-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f4f3df6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:2f4f683a-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f4f95bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:2f4f95bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:2f4fc4f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2f4fee22-7972-11ec-93d9-0242ac110002 UniProtKB:O08703 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:2f5018ac-7972-11ec-93d9-0242ac110002 UniProtKB:O70344 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:2f50446c-7972-11ec-93d9-0242ac110002 UniProtKB:P97414 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2f506e60-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.39']} DrugCentral uuid:2f509764-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.7']} DrugCentral uuid:2f50c13a-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:2f50ea66-7972-11ec-93d9-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin is agonist of GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:2f51267a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:2f51267a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:2f51267a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:2f51267a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:2f51267a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:2f51267a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:2f51803e-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.736']} DrugCentral uuid:2f51a96a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07806 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:2f51d2a0-7972-11ec-93d9-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.317']} DrugCentral uuid:2f51fe6a-7972-11ec-93d9-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:2f522778-7972-11ec-93d9-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2f52507c-7972-11ec-93d9-0242ac110002 UniProtKB:A4ZYU9 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:2f527a02-7972-11ec-93d9-0242ac110002 UniProtKB:Q83TT7 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Unclassified (AmpC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:2f52a3ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q3S5C3 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Transporter (Efflux transporter; SugE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:2f52cd0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q48435 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:2f52f5fe-7972-11ec-93d9-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:2f531f66-7972-11ec-93d9-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:2f535f30-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f535f30-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f535f30-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f535f30-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f535f30-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f535f30-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f535f30-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2f53c4d4-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.269']} DrugCentral uuid:2f53edc4-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.716']} DrugCentral uuid:2f5416c8-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:2f544134-7972-11ec-93d9-0242ac110002 UniProtKB:P60932 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Unclassified (Undecaprenyl-diphosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:2f546eca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (GABA B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f546eca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (GABA B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f54a7c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen is agonist of GPCR (GABA-B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:2f54a7c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen is agonist of GPCR (GABA-B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:2f54dcf2-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f553f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f5627c4-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:2f564c90-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:2f56717a-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:2f569664-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:2f56bb1c-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:2f56e060-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:2f57095a-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.25']} DrugCentral uuid:2f573286-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:2f575ba8-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:2f5785b0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bamipine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:2f57ae64-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 barnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:2f57ae64-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 barnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:2f57dde4-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.427']} DrugCentral uuid:2f58079c-7972-11ec-93d9-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:2f5830c8-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:2f585aee-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f588410-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2f58ada0-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:2f58d6b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:2f590052-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:2f592960-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Y34 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate is agonist of GPCR (Probable G-protein coupled receptor 97) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:2f59553e-7972-11ec-93d9-0242ac110002 UniProtKB:P04401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Unclassified (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:2f597e88-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f59a78c-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belotecan is inhibitor of Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.561']} DrugCentral uuid:2f59d13a-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:2f59fa48-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2f5a2360-7972-11ec-93d9-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:2f5a4d54-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:2f5a76c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:2f5a9fe8-7972-11ec-93d9-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:2f5ac914-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:2f5af222-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:2f5b1c3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:2f5b454c-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:2f5b6a36-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.3']} DrugCentral uuid:2f5b9326-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:2f5bb888-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:2f5bdd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:2f5c022a-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benoxaprofen is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:2f5c26e2-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benoxaprofen targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:2f5c5068-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.57']} DrugCentral uuid:2f5c79bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:2f5ca2ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:2f5ccc0a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:2f5cf662-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.18']} DrugCentral uuid:2f5d1fa2-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2f5d48e2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:2f5d7218-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:2f5d9bda-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.131']} DrugCentral uuid:2f5dc4de-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.105']} DrugCentral uuid:2f5dee14-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:2f5e179a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:2f5e41fc-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:2f5e6bfa-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:2f5e951c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:2f5ebeca-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.486']} DrugCentral uuid:2f5ee7b0-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:2f5f187a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:2f5f187a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:2f5f187a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:2f5f5a1a-7972-11ec-93d9-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:2f5f7f72-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:2f5fa876-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:2f5fd558-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:2f5fd558-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:2f600afa-7972-11ec-93d9-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:2f60341c-7972-11ec-93d9-0242ac110002 UniProtKB:P03313 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Unclassified (Genome polyprotein [Cleaved into: P1; Capsid protein VP0) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:2f605d34-7972-11ec-93d9-0242ac110002 UniProtKB:P52789 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Kinase (Hexokinase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:2f6086d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzarone targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:2f60b072-7972-11ec-93d9-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2f60d980-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:2f610298-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:2f612c32-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:2f615536-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:2f617e3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:2f61a748-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:2f61d114-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.976']} DrugCentral uuid:2f61fa0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.908']} DrugCentral uuid:2f622420-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.711']} DrugCentral uuid:2f624d1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:2f6278da-7972-11ec-93d9-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2f62a1de-7972-11ec-93d9-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.32']} DrugCentral uuid:2f62cb00-7972-11ec-93d9-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:2f62f422-7972-11ec-93d9-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:2f631dbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2f6346e8-7972-11ec-93d9-0242ac110002 UniProtKB:O15392 biolink:molecularly_interacts_with DrugCentral:321 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benziodarone targets Unclassified (Baculoviral IAP repeat-containing protein 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:2f636ff6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:321 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benziodarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:2f6399b8-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:2f63be84-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:2f63e36e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:2f640952-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:2f642e1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:2f64563c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:2f647b9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UI33 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 11 subunit alpha) DrugCentral uuid:2f64a06a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:2f64c522-7972-11ec-93d9-0242ac110002 UniProtKB:Q01118 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 7 subunit alpha) DrugCentral uuid:2f64ea66-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['3.495']} DrugCentral uuid:2f651374-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzonatate targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:2f653818-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:2f655cf8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:2f658250-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:2f65a730-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:2f65cc10-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:2f65f528-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2f6620ac-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.445']} DrugCentral uuid:2f6649b0-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.241']} DrugCentral uuid:2f6673b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.865']} DrugCentral uuid:2f669cd0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:2f66c66a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:2f66ef78-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:2f671462-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.17']} DrugCentral uuid:2f673dca-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:2f676282-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:2f678730-7972-11ec-93d9-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:2f67ac10-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:2f67d53c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:2f67ff3a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:2f682848-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:2f685142-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.157']} DrugCentral uuid:2f687ad2-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:2f68a408-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:2f68cd3e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.888']} DrugCentral uuid:2f68f674-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:2f692022-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.654']} DrugCentral uuid:2f694944-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:2f697266-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.926']} DrugCentral uuid:2f699b92-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.636']} DrugCentral uuid:2f69c6e4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:2f69f010-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:2f6a190a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:2f6a4222-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:2f6a6b8a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:2f6a95ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.253']} DrugCentral uuid:2f6abf40-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:2f6ae90c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:2f6b1242-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:2f6b3b50-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:2f6b644a-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:2f6b8ea2-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:2f6bbac6-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:2f6be6ea-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:2f6c103e-7972-11ec-93d9-0242ac110002 UniProtKB:Q695T7 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:2f6c39c4-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzyl benzoate targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:2f6c62be-7972-11ec-93d9-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzyl benzoate targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:2f6c8bcc-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepotastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:2f6cb08e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:2f6cd5b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:2f6cfed6-7972-11ec-93d9-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:2f6d2802-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.149']} DrugCentral uuid:2f6d512e-7972-11ec-93d9-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:2f6d7c6c-7972-11ec-93d9-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2f6da584-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:2f6dce7e-7972-11ec-93d9-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:2f6e0038-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:2f6e0038-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:2f6e0038-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:2f6e416a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is gating inhibitor of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f6e6b72-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:2f6e90b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:2f6eb578-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:2f6ede86-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:2f6f07b2-7972-11ec-93d9-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2f6f31f6-7972-11ec-93d9-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:2f6f5e10-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:2f6f870a-7972-11ec-93d9-0242ac110002 UniProtKB:Q2Q167 biolink:molecularly_interacts_with DrugCentral:345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betacarotene targets Unclassified (Core protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:2f6fb158-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betahistine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:2f6fdb4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betahistine is inverse agonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:2f70045a-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:2f702d5e-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone targets Cytosolic other (Annexin A1) DrugCentral uuid:2f705234-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:2f707778-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone benzoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:2f709c62-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:2f70c1b0-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone dipropionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:2f70eabe-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone valerate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:2f711110-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamipron targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:2f713a64-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamipron targets Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:2f716390-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:2f718d16-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:2f71b6ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.98']} DrugCentral uuid:2f71e00e-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:2f72091c-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.53']} DrugCentral uuid:2f723252-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.76']} DrugCentral uuid:2f725bec-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betazole is agonist of GPCR (Histamine H2 receptor) DrugCentral uuid:2f7280ae-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:2f72aaca-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:2f72d3f6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:2f72fde0-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:2f732716-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:2f735024-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VH27 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol targets GPCR (Muscarinic receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f7379fa-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betanidine is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:2f739ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bevantolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:2f73c36a-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:2f73ec8c-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is antagonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:2f741626-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:2f743f52-7972-11ec-93d9-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:2f746892-7972-11ec-93d9-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:2f7491aa-7972-11ec-93d9-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f74bcb6-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:2f74e858-7972-11ec-93d9-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:2f751170-7972-11ec-93d9-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:2f753a92-7972-11ec-93d9-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2f75642c-7972-11ec-93d9-0242ac110002 UniProtKB:Q05343 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2f758d44-7972-11ec-93d9-0242ac110002 UniProtKB:O43174 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Enzyme (Cytochrome P450 26A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:2f75b79c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NR63 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Enzyme (Cytochrome P450 26B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:2f75e0a0-7972-11ec-93d9-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:2f760af8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13133 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear other (Oxysterols receptor LXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:2f7633f2-7972-11ec-93d9-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Enzyme (Lipoprotein lipase) DrugCentral uuid:2f7658be-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:2f7682bc-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.178']} DrugCentral uuid:2f76ad46-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:2f76d640-7972-11ec-93d9-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.48']} DrugCentral uuid:2f76ff44-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:2f7728e8-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) DrugCentral uuid:2f774d96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:2f777258-7972-11ec-93d9-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:2f77972e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:2f77bc5e-7972-11ec-93d9-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:2f77e116-7972-11ec-93d9-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:2f7805f6-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:2f782f36-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2f785948-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:2f7882b0-7972-11ec-93d9-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:2f78abc8-7972-11ec-93d9-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:2f78d4d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q63449 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:2f78fe84-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifemelane targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:2f79281e-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:2f79512c-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:2f797a6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:2f79a3de-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:2f79cd6e-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bimatoprost targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2f79f690-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bimatoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:2f7a1fda-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biotin targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2f7a4bae-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.32']} DrugCentral uuid:2f7a753e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:2f7a9e42-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:2f7ac8f4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.62']} DrugCentral uuid:2f7af1f8-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.201']} DrugCentral uuid:2f7b1ae8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:2f7b3faa-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:2f7b6930-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.011']} DrugCentral uuid:2f7b93b0-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2f7bbc96-7972-11ec-93d9-0242ac110002 UniProtKB:P15559 biolink:molecularly_interacts_with DrugCentral:376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisantrene targets Enzyme (NAD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:2f7be5b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:2f7c10ec-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:2f7c3a04-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:2f7c6312-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:2f7c8c2a-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:2f7cb5ba-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisulepine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:2f7cda86-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bitolterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:2f7cff48-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bivalirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:2f7d2856-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:2f7d51be-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:2f7d7af4-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.854']} DrugCentral uuid:2f7da42a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.092']} DrugCentral uuid:2f7dcd2e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:2f7dfa1a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.345']} DrugCentral uuid:2f7e2396-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.014']} DrugCentral uuid:2f7e4c9a-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.463']} DrugCentral uuid:2f7e762a-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.262']} DrugCentral uuid:2f7e9ef2-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:2f7ec7f6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:2f7ef212-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.65']} DrugCentral uuid:2f7f1bb6-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:2f7f44d8-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2f7f6dfa-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:2f7f971c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:2f7fc200-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:2f7feb0e-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2f80141c-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:2f803d34-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:2f8066ba-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:2f808fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.745']} DrugCentral uuid:2f80b908-7972-11ec-93d9-0242ac110002 UniProtKB:Q99460 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Cytosolic other (26S proteasome non-ATPase regulatory subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:2f80e306-7972-11ec-93d9-0242ac110002 UniProtKB:P25786 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit alpha type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.208']} DrugCentral uuid:2f810cb4-7972-11ec-93d9-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:2f8135c2-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:2f815eda-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:2f818946-7972-11ec-93d9-0242ac110002 UniProtKB:P08311 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Cathepsin G) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:2f81b394-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:2f81dc98-7972-11ec-93d9-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:2f820592-7972-11ec-93d9-0242ac110002 UniProtKB:P17538 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Chymotrypsinogen B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:2f822f40-7972-11ec-93d9-0242ac110002 UniProtKB:P28062 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:2f82584e-7972-11ec-93d9-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:2f828166-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:2f82aa74-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:2f82d422-7972-11ec-93d9-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:2f82fd44-7972-11ec-93d9-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:2f83276a-7972-11ec-93d9-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:2f83517c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:2f837c9c-7972-11ec-93d9-0242ac110002 UniProtKB:A5PKW4 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Unclassified (PH and SEC7 domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:2f83ad52-7972-11ec-93d9-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:2f83ad52-7972-11ec-93d9-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:2f83ad52-7972-11ec-93d9-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:2f83eef2-7972-11ec-93d9-0242ac110002 UniProtKB:P00766 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Alpha-chymotrypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:2f8417f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IJT1 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:2f8440fa-7972-11ec-93d9-0242ac110002 UniProtKB:P28063 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.78']} DrugCentral uuid:2f846a26-7972-11ec-93d9-0242ac110002 UniProtKB:P28065 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:2f849384-7972-11ec-93d9-0242ac110002 UniProtKB:P40306 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:2f84bc88-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:2f84e12c-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:2f850a44-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:2f8534e2-7972-11ec-93d9-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2f855de6-7972-11ec-93d9-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:2f8586e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q29010 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:2f85afd0-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:2f85d938-7972-11ec-93d9-0242ac110002 UniProtKB:P21451 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:2f860232-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:2f8626cc-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:2f864b84-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:2f8670be-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.387']} DrugCentral uuid:2f8699c2-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:2f86c352-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:2f86ec88-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:2f8718de-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:2f8741ce-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.073']} DrugCentral uuid:2f876af0-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:2f879534-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:2f87bea6-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:2f87e7b4-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:2f881856-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f881856-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f881856-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f8861bc-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:2f8861bc-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:2f8861bc-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:2f88a30c-7972-11ec-93d9-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:2f88cc10-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:2f88f80c-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:2f892124-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2f894a3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:2f8973c2-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:2f899cda-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f89c5e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f89eee2-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:2f8a185e-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:2f8a416c-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:2f8a6a7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:2f8a939c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:2f8abe30-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:2f8ae838-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2f8b1164-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:2f8b3a7c-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:2f8b6448-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:2f8b8d60-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2f8bb66e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:2f8bdff4-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:2f8c090c-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:2f8c329c-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:2f8c5baa-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:2f8c86c0-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:2f8cb01e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:2f8cd936-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:2f8d0226-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2f8d2c1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:2f8d565e-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:2f8d7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:2f8da866-7972-11ec-93d9-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2f8dd1c4-7972-11ec-93d9-0242ac110002 UniProtKB:P06479 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f8dfabe-7972-11ec-93d9-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:2f8e23b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:2f8e4c9e-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:2f8e76a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:2f8e9fa0-7972-11ec-93d9-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:2f8ec8b8-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:2f8ef34c-7972-11ec-93d9-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:2f8f1c46-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:2f8f454a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:2f8f760a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2f8f760a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2f8f760a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2f8fb052-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2f8fd94c-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:2f90062e-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2f90062e-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2f903e00-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:2f906722-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:2f909030-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.708']} DrugCentral uuid:2f90b93e-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:2f90e30a-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.858']} DrugCentral uuid:2f910c18-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:2f913530-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:2f915eb6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:2f9187ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:2f91b0e6-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:2f91d9ea-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:2f92044c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2f922d5a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2f925672-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:2f927f8a-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2f92a942-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:2f92d336-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2f92fd98-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2f9326ba-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2f9350ae-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:2f9379bc-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:2f93a2ca-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:2f93cc8c-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2f93f5e0-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:2f941ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.86']} DrugCentral uuid:2f94481a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:2f9471c8-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.708']} DrugCentral uuid:2f949acc-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:2f94c3d0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:2f94ecb6-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2f951632-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:2f953f36-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:2f95683a-7972-11ec-93d9-0242ac110002 UniProtKB:Q7TSF2 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Transporter (Vesicular glutamate transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:2f959116-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2f95c334-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:2f95c334-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:2f95c334-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:2f9613ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f9613ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f9613ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f9613ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f9613ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f9672ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:2f9672ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:2f96a7b8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:2f96d0bc-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:2f96fa38-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromopride targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:2f972328-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2f974c36-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:2f9775ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:2f979f42-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2f97c850-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2f97f14a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:2f981b0c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.119']} DrugCentral uuid:2f98441a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.745']} DrugCentral uuid:2f986e54-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:2f98974e-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:2f98c0c0-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.319']} DrugCentral uuid:2f98e9ce-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:2f9912d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:2f993bea-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.218']} DrugCentral uuid:2f996ffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:2f996ffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:2f996ffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:2f99b11a-7972-11ec-93d9-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brotizolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:2f99da1e-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:2f9a04bc-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buclizine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:2f9a2960-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:2f9a4e36-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:2f9a7726-7972-11ec-93d9-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:2f9aa070-7972-11ec-93d9-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.5']} DrugCentral uuid:2f9ac974-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:2f9af2f0-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:2f9b1bd6-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.701']} DrugCentral uuid:2f9b4660-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.963']} DrugCentral uuid:2f9b6f8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:2f9b98b8-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:2f9bc270-7972-11ec-93d9-0242ac110002 UniProtKB:P04401 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Unclassified (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:2f9beb56-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:2f9c2b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2f9c2b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2f9c2b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2f9c2b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2f9c2b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2f9c2b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2f9c2b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:2f9c9d12-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:2f9cc1e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2f9ceb96-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:2f9d1580-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:2f9d3a24-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:2f9d5ee6-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1D adrenergic receptor) DrugCentral uuid:2f9d84b6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:2f9dab12-7972-11ec-93d9-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:2f9dcfca-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:2f9df8ba-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:2f9e21d2-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:2f9e4b4e-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:2f9e7006-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ks', 'has_quantitative_value': ['4.59']} DrugCentral uuid:2f9e9928-7972-11ec-93d9-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:2f9ec240-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:2f9eee64-7972-11ec-93d9-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2f9f174a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:2f9f4030-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:2f9f65a6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:2f9f8a72-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:2f9faf2a-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) DrugCentral uuid:2f9fd400-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.399']} DrugCentral uuid:2f9ffd36-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.263']} DrugCentral uuid:2fa026c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:2fa04fca-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.585']} DrugCentral uuid:2fa078ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:2fa0a2f4-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.593']} DrugCentral uuid:2fa0cc0c-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:2fa0f51a-7972-11ec-93d9-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2fa11e32-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2fa147ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:2fa170d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:2fa19a42-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.293']} DrugCentral uuid:2fa1c42c-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2fa1ed94-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.514']} DrugCentral uuid:2fa21698-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:2fa23f7e-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.233']} DrugCentral uuid:2fa2686e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:2fa29348-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2fa2bc6a-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:2fa2e550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z0V1 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:2fa30ed6-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:2fa337c6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:2fa360e8-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2fa38b4a-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2fa3b4da-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.29']} DrugCentral uuid:2fa3ddde-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:2fa406ec-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:2fa42ffa-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:2fa45a20-7972-11ec-93d9-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:2fa4832e-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.89']} DrugCentral uuid:2fa4ac32-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:2fa4d54a-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:2fa4fec6-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:2fa527ca-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:2fa550e2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:2fa579d2-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.796']} DrugCentral uuid:2fa5a42a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:2fa5cdf6-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:2fa5f29a-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:2fa61c8e-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:2fa645c4-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.846']} DrugCentral uuid:2fa66ef0-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:2fa69bc8-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:2fa69bc8-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:2fa6d55c-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2fa6d55c-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2fa70a68-7972-11ec-93d9-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.569']} DrugCentral uuid:2fa73380-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.52']} DrugCentral uuid:2fa75ce8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01776 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:2fa785ba-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:2fa7aeb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:2fa7d7cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2fa8031e-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:2fa82c22-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:2fa85512-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:2fa87e16-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:2fa8a7d8-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:2fa8d0e6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.435']} DrugCentral uuid:2fa8f9fe-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:2fa9230c-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2fa94c9c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.277']} DrugCentral uuid:2fa976e0-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:2fa9a110-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.471']} DrugCentral uuid:2fa9cb54-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:2fa9f480-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:2faa1d98-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:2faa46ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:2faa7068-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2faa9976-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:2faac298-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:2faaeba6-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:2fab150e-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2fab3e12-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:2fab6702-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2fab8ffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:2fabbb12-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:2fabe402-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:2fac0d10-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:2fac421c-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:2fac421c-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:2fac421c-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:2fac421c-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:2fac9726-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2fac9726-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2fac9726-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2face848-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:2face848-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:2face848-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:2face848-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:2face848-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:2fad4a40-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:2fad4a40-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:2fad4a40-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:2fad966c-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:2fad966c-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:2fad966c-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:2fadd7b2-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 busulfan targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.283']} DrugCentral uuid:2fae08ae-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2fae08ae-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2fae08ae-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2fae4c10-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:2fae4c10-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:2fae4c10-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:2fae85e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:2faeaf48-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.779']} DrugCentral uuid:2faed8ec-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.125']} DrugCentral uuid:2faf01f0-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:2faf2aea-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:2faf54b6-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.161']} DrugCentral uuid:2faf7dba-7972-11ec-93d9-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:2fafa27c-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.805']} DrugCentral uuid:2fafcbbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:2faff542-7972-11ec-93d9-0242ac110002 UniProtKB:Q92206 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.347']} DrugCentral uuid:2fb01f54-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butoconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:2fb04434-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:2fb06d6a-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol is partial agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:2fb0970e-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:2fb0c030-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:2fb0e920-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:2fb1122e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.405']} DrugCentral uuid:2fb13d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:2fb16238-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:2fb18704-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:2fb1abbc-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:2fb1d0ec-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2fb1fa2c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:2fb22358-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:2fb24c70-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2fb27600-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:2fb29f18-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:2fb2c826-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:2fb2f2c4-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:2fb31c22-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:2fb34544-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:2fb36e70-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2fb397f6-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2fb3c118-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2fb3eb66-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2fb41488-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2fb43eea-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:2fb467f8-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:2fb490fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cadralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:2fb4b5be-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cadralazine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:2fb4e142-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:2fb50a8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:2fb53390-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:2fb55ca8-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2fb588a4-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:2fb5b1bc-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:2fb5daac-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:2fb6040a-7972-11ec-93d9-0242ac110002 UniProtKB:P00489 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Glycogen phosphorylase, muscle form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:2fb62cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2fb65608-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:2fb67f16-7972-11ec-93d9-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:2fb6aa68-7972-11ec-93d9-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:2fb6d754-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:2fb6d754-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:2fb717b4-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:2fb717b4-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:2fb717b4-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:2fb717b4-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:2fb76548-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2T3 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Guanine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:2fb78e42-7972-11ec-93d9-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:2fb7b732-7972-11ec-93d9-0242ac110002 UniProtKB:Q60614 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2fb7e0ae-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcifediol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:2fb80656-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:465 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcipotriene is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.51']} DrugCentral uuid:2fb82f50-7972-11ec-93d9-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:2fb85426-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2fb87ea6-7972-11ec-93d9-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:2fb8a37c-7972-11ec-93d9-0242ac110002 UniProtKB:P02774 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Secreted (Vitamin D-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:2fb8cc8a-7972-11ec-93d9-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:2fb8f5a2-7972-11ec-93d9-0242ac110002 UniProtKB:O42392 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.6']} DrugCentral uuid:2fb91f1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q28037 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:2fb9480e-7972-11ec-93d9-0242ac110002 UniProtKB:A3RGC1 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.15']} DrugCentral uuid:2fb97248-7972-11ec-93d9-0242ac110002 UniProtKB:Q9PTN2 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Nuclear hormone receptor (Vitamin D3 receptor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:2fb99b42-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camphor targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:2fb9c4be-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camphor is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:2fb9edb8-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:2fba16bc-7972-11ec-93d9-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat is inhibitor of Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2fba40b0-7972-11ec-93d9-0242ac110002 UniProtKB:P06870 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Kallikrein-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:2fba6a2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01177 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:2fba9330-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:2fbabc2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:2fbae588-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:2fbb0e82-7972-11ec-93d9-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:2fbb377c-7972-11ec-93d9-0242ac110002 UniProtKB:Q04756 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Hepatocyte growth factor activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:2fbb610c-7972-11ec-93d9-0242ac110002 UniProtKB:O15393 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat is inhibitor of Enzyme (Transmembrane protease serine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2fbb8a74-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:472 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camylofin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:2fbbb364-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:2fbbdc5e-7972-11ec-93d9-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:2fbc0580-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:2fbc324e-7972-11ec-93d9-0242ac110002 UniProtKB:P34976 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:2fbc5b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBT6 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase kappa) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:2fbc847e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNA4 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase iota) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:2fbcad96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y253 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase eta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:2fbcd71c-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:2fbd0020-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:2fbd2924-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:2fbd52c8-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:2fbd7bea-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:2fbda516-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:2fbdce56-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:2fbdf958-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:2fbe223e-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:2fbe4b4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canrenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:2fbe743c-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capecitabine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:2fbe9958-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:2fbec310-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2fbeec46-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2fbf1572-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:2fbf3eda-7972-11ec-93d9-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:2fbf690a-7972-11ec-93d9-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:2fbf9236-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:2fbfbb4e-7972-11ec-93d9-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2fbfe70e-7972-11ec-93d9-0242ac110002 UniProtKB:P44514 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Succinyl-diaminopimelate desuccinylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:2fc01012-7972-11ec-93d9-0242ac110002 UniProtKB:Q79MP6 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:2fc039f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q93T40 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase II) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:2fc06382-7972-11ec-93d9-0242ac110002 UniProtKB:Q9K2N0 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Unclassified (Beta-lactamase class B VIM-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:2fc08d30-7972-11ec-93d9-0242ac110002 UniProtKB:C7C422 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase NDM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.85']} DrugCentral uuid:2fc0b63e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.81']} DrugCentral uuid:2fc0df74-7972-11ec-93d9-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2fc108e6-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:2fc13212-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:2fc15b34-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:2fc1844c-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.94']} DrugCentral uuid:2fc1b07a-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:2fc1da0a-7972-11ec-93d9-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2fc20322-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2fc22c26-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:2fc255c0-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:2fc27ece-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:2fc2a7a0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:2fc2d108-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:2fc2fa02-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.577']} DrugCentral uuid:2fc322e8-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:2fc34bd8-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:2fc376f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:2fc3a024-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:2fc3c93c-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:2fc3f240-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2fc41bb2-7972-11ec-93d9-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:2fc445d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2fc46ef0-7972-11ec-93d9-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:2fc49808-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.74']} DrugCentral uuid:2fc4c17a-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2fc4ee5c-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:2fc4ee5c-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:2fc52746-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:2fc52746-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:2fc56580-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:2fc56580-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:2fc59e88-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:2fc59e88-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:2fc5d7ea-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2fc5d7ea-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:2fc61106-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:2fc61106-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:2fc65602-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:2fc65602-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:2fc65602-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:2fc65602-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:2fc65602-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:2fc6afe4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:2fc6d49c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.495']} DrugCentral uuid:2fc6fd96-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.125']} DrugCentral uuid:2fc72802-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:2fc7521e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:2fc77b22-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:2fc7a796-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2fc7a796-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2fc7a796-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:2fc7e5a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:2fc7e5a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:2fc81ac8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H461 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is allosteric modulator of GPCR (Frizzled-8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2fc843d6-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:2fc86d48-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2fc89638-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fc8d1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fc8d1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fc8d1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fc8d1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fc8d1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fc8d1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fc8d1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fc9380e-7972-11ec-93d9-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone is inhibitor of Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:2fc96112-7972-11ec-93d9-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:2fc98a7a-7972-11ec-93d9-0242ac110002 UniProtKB:P51661 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:2fc9b4b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.71']} DrugCentral uuid:2fc9ddea-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:2fca070c-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:2fca30ba-7972-11ec-93d9-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:2fca59dc-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:2fca82ea-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:2fcaad42-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:2fcad894-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:2fcb01ac-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.232']} DrugCentral uuid:2fcb2b00-7972-11ec-93d9-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.149']} DrugCentral uuid:2fcb5440-7972-11ec-93d9-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa is inhibitor of Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:2fcb7970-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.168']} DrugCentral uuid:2fcba288-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:2fcbcba0-7972-11ec-93d9-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:2fcbf530-7972-11ec-93d9-0242ac110002 UniProtKB:P22079 biolink:molecularly_interacts_with DrugCentral:497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbimazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:2fcc1e2a-7972-11ec-93d9-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbimazole is inhibitor of Enzyme (Thyroid peroxidase) DrugCentral uuid:2fcc4300-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbinoxamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:2fcc6844-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carboprost is agonist of GPCR (Prostaglandin F2-alpha receptor) DrugCentral uuid:2fcc9256-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:2fcc9256-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:2fccde78-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fccde78-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fccde78-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fccde78-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fccde78-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fccde78-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fccde78-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fcd428c-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:510 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carubicin targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:2fcd6744-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:2fcd9048-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.213']} DrugCentral uuid:2fcdb97e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6P7S1 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Acid ceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:2fcde3ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q13510 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Acid ceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:2fce0cb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6N5 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Unclassified (Sulfide:quinone oxidoreductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:2fce35b6-7972-11ec-93d9-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmustine is inhibitor of Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:2fce5faa-7972-11ec-93d9-0242ac110002 UniProtKB:P50416 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine O-palmitoyltransferase 1, liver isoform) DrugCentral uuid:2fce8674-7972-11ec-93d9-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:2fceafa0-7972-11ec-93d9-0242ac110002 UniProtKB:P18886 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine palmitoyltransferase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:2fceda16-7972-11ec-93d9-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:515 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carperitide targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10']} DrugCentral uuid:2fcf0388-7972-11ec-93d9-0242ac110002 UniProtKB:P18910 biolink:molecularly_interacts_with DrugCentral:515 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carperitide targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:2fcf2c82-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfenazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:2fcf5162-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfenazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:2fcf761a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carpipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:2fcf9fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carpipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:2fcfc91c-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:2fcff22a-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:2fd01b38-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2fd045c2-7972-11ec-93d9-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:2fd06f2a-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:2fd0982e-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:2fd0c13c-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carteolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:2fd0eacc-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carteolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:2fd113d0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carumonam targets Enzyme (Peptidoglycan synthase FtsI) DrugCentral uuid:2fd1389c-7972-11ec-93d9-0242ac110002 UniProtKB:Q92736 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is inhibitor of Ion channel (Ryanodine receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:2fd161aa-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.742']} DrugCentral uuid:2fd18b8a-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:2fd1b4ac-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:2fd1ddce-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.126']} DrugCentral uuid:2fd2070e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:2fd23166-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:2fd25a74-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:2fd28472-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.928']} DrugCentral uuid:2fd2adf8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.273']} DrugCentral uuid:2fd2d724-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.476']} DrugCentral uuid:2fd3005a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:2fd32968-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:2fd3530c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:2fd37c38-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.152']} DrugCentral uuid:2fd3a564-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:2fd3ce7c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:2fd3fa0a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:2fd4234a-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:2fd44c6c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:2fd47598-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:2fd49f0a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.054']} DrugCentral uuid:2fd4c836-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:2fd4f270-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:2fd51c3c-7972-11ec-93d9-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium channel subfamily K member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2fd54540-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.706']} DrugCentral uuid:2fd56e80-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:2fd597c0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:2fd5c1be-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:2fd5eaea-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.09']} DrugCentral uuid:2fd61416-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:2fd63d24-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:2fd6668c-7972-11ec-93d9-0242ac110002 UniProtKB:O00206 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Membrane receptor (Toll-like receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:2fd690a8-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:2fd6b9b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefacetrile targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fd6de82-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fd703ee-7972-11ec-93d9-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:2fd743cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd743cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd743cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd743cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd743cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd743cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd743cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd7a88a-7972-11ec-93d9-0242ac110002 UniProtKB:P46059 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil targets Transporter (Solute carrier family 15 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.14']} DrugCentral uuid:2fd7e868-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd7e868-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd7e868-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd7e868-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd7e868-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd7e868-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd7e868-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd84c86-7972-11ec-93d9-0242ac110002 UniProtKB:P46059 biolink:molecularly_interacts_with DrugCentral:527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole targets Transporter (Solute carrier family 15 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.09']} DrugCentral uuid:2fd88cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd88cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd88cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd88cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd88cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd88cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd88cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd8f15e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fd92e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd92e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd92e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd92e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd92e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd92e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd92e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fd99604-7972-11ec-93d9-0242ac110002 UniProtKB:O54286 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Enzyme (Pencillin binding protein 2a; Penicillin binding protein 2'; Penicillin binding protein, PBP2; Penicillin-binding protein 2; Penicillin-binding protein 2'; Peptidase) DrugCentral uuid:2fd9babc-7972-11ec-93d9-0242ac110002 UniProtKB:Q14TG6 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:2fd9df74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:2fda1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fda1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fda1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fda1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fda1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fda1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fda1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fda82bc-7972-11ec-93d9-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:2fdaac2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14TG6 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:2fdad0e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q54906 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil targets Enzyme (Penicillin-binding protein) DrugCentral uuid:2fdb0c64-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb0c64-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb0c64-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb0c64-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb0c64-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb0c64-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb0c64-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb8c34-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb8c34-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb8c34-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb8c34-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb8c34-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb8c34-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdb8c34-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdbf156-7972-11ec-93d9-0242ac110002 UniProtKB:P42971 biolink:molecularly_interacts_with DrugCentral:536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefetamet pivoxil targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:2fdc1618-7972-11ec-93d9-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefetamet pivoxil targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:2fdc3ac6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:2fdc64f6-7972-11ec-93d9-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:2fdca54c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdca54c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdca54c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdca54c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdca54c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdca54c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdca54c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdd08b6-7972-11ec-93d9-0242ac110002 UniProtKB:P19174 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets Enzyme (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:2fdd4934-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdd4934-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdd4934-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdd4934-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdd4934-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdd4934-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdd4934-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fddad0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fdde880-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdde880-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdde880-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdde880-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdde880-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdde880-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdde880-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fde4ca8-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:2fde75ca-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:2fde9ece-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:2fdec7d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fdeef46-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:2fdf1886-7972-11ec-93d9-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:2fdf586e-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdf586e-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdf586e-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdf586e-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdf586e-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdf586e-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdf586e-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdfbc50-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fdff918-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdff918-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdff918-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdff918-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdff918-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdff918-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fdff918-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe05d4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fe09954-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe09954-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe09954-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe09954-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe09954-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe09954-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe09954-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe102a4-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:2fe12bbc-7972-11ec-93d9-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.512']} DrugCentral uuid:2fe15574-7972-11ec-93d9-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.659']} DrugCentral uuid:2fe17e82-7972-11ec-93d9-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2fe1a786-7972-11ec-93d9-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2fe1d0a8-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.617']} DrugCentral uuid:2fe1fb32-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:2fe2242c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fe248d0-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:2fe271b6-7972-11ec-93d9-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:2fe29cae-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:2fe2c756-7972-11ec-93d9-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2fe30720-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe30720-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe30720-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe30720-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe30720-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe30720-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe30720-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe36b02-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fe38fb0-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:2fe3b8aa-7972-11ec-93d9-0242ac110002 UniProtKB:P32241 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets GPCR (Vasoactive intestinal polypeptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:2fe3f914-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe3f914-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe3f914-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe3f914-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe3f914-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe3f914-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe3f914-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe45ec2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fe483d4-7972-11ec-93d9-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) DrugCentral uuid:2fe4a88c-7972-11ec-93d9-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:2fe4d19a-7972-11ec-93d9-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:2fe4fb16-7972-11ec-93d9-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:2fe52424-7972-11ec-93d9-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:2fe563c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe563c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe563c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe563c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe563c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe563c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe563c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe5dff4-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe5dff4-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe5dff4-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe5dff4-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe5dff4-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe5dff4-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe5dff4-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe64458-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefprozil targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fe66924-7972-11ec-93d9-0242ac110002 UniProtKB:P25098 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:2fe69228-7972-11ec-93d9-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.522']} DrugCentral uuid:2fe6bb2c-7972-11ec-93d9-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:2fe6e480-7972-11ec-93d9-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:2fe70d8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:2fe73674-7972-11ec-93d9-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:2fe75f82-7972-11ec-93d9-0242ac110002 UniProtKB:Q5A7N4 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Unclassified (tRNA 2'-phosphotransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:2fe7893a-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.261']} DrugCentral uuid:2fe7b248-7972-11ec-93d9-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.534']} DrugCentral uuid:2fe7db6a-7972-11ec-93d9-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:2fe80450-7972-11ec-93d9-0242ac110002 UniProtKB:Q1J5W5 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten targets Enzyme (Penicillin-binding protein) DrugCentral uuid:2fe82b7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q60FU1 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:2fe8676a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe8676a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe8676a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe8676a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe8676a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe8676a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe8676a-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe8ccf0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fe8f1b2-7972-11ec-93d9-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime targets Enzyme (Beta-lactamase) DrugCentral uuid:2fe92d26-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe92d26-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe92d26-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe92d26-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe92d26-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe92d26-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe92d26-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2fe991d0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.142']} DrugCentral uuid:2fe9bad4-7972-11ec-93d9-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.513']} DrugCentral uuid:2fe9e540-7972-11ec-93d9-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.744']} DrugCentral uuid:2fea101a-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.213']} DrugCentral uuid:2fea3932-7972-11ec-93d9-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:2fea6236-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2fea8752-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:2feab074-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:2fead98c-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:2feb1a50-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb1a50-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb1a50-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb1a50-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb1a50-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb1a50-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb1a50-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb94f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb94f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb94f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb94f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb94f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb94f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2feb94f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2febfd30-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:2fec263e-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:2fec4fba-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.854']} DrugCentral uuid:2fec78dc-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.477']} DrugCentral uuid:2feca1f4-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:2feccb0c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:2fecf4b0-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.917']} DrugCentral uuid:2fed1de6-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:2fed46e0-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:2fed6fd0-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.856']} DrugCentral uuid:2fed9b18-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:2fedc412-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:2feded16-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:2fee1624-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:2fee3f82-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:2fee687c-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:2fee9176-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:2feeba70-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:2feee450-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:2fef0db8-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.033']} DrugCentral uuid:2fef36d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:2fef622c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:2fef8ba8-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:2fefb4ac-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:2fefddb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:2ff0072c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:2ff03012-7972-11ec-93d9-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:2ff05916-7972-11ec-93d9-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:2ff08210-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.627']} DrugCentral uuid:2ff0abf0-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.29']} DrugCentral uuid:2ff0d4f4-7972-11ec-93d9-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:2ff0fe02-7972-11ec-93d9-0242ac110002 UniProtKB:Q8SPQ9 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:2ff126fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:2ff15104-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:2ff17a08-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:2ff1a442-7972-11ec-93d9-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:2ff1cdbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:2ff1f6e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8HZR1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:2ff21fda-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:2ff248de-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:2ff2728c-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:2ff29b86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:2ff2c4b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:2ff2edca-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:2ff318fe-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:2ff34252-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:2ff36b88-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:2ff3959a-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:2ff3bf0c-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:2ff3e81a-7972-11ec-93d9-0242ac110002 UniProtKB:O78750 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:2ff41128-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:2ff43a36-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:2ff46466-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:2ff48d7e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:2ff4b6a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:2ff4e116-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:2ff50c5e-7972-11ec-93d9-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:2ff53558-7972-11ec-93d9-0242ac110002 UniProtKB:O78749 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:2ff55e48-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:2ff5879c-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:2ff5b096-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:2ff5d99a-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:2ff6029e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:2ff62c60-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:2ff6556e-7972-11ec-93d9-0242ac110002 UniProtKB:P42971 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:2ff67a1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16348 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin targets Transporter (Solute carrier family 15 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:2ff6bbee-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff6bbee-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff6bbee-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff6bbee-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff6bbee-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff6bbee-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff6bbee-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff7390c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff7390c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff7390c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff7390c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff7390c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff7390c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff7390c-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff79e38-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:2ff7c728-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2ff7ec8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:2ff815a2-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:2ff83e92-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Transporter (Solute carrier family 22 member 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:2ff8678c-7972-11ec-93d9-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:2ff891b2-7972-11ec-93d9-0242ac110002 UniProtKB:P35236 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:2ff8d190-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff8d190-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff8d190-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff8d190-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff8d190-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff8d190-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff8d190-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ff9357c-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:2ff95e58-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:2ff9875c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:2ff9b042-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:2ff9da0e-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:2ffa02ea-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:2ffa2bda-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:2ffa54ac-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:2ffa813e-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:2ffaab5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2ffacffe-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:2ffaf966-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:2ffb2256-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:2ffb4b50-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:2ffb745e-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:2ffb9e0c-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:2ffbc6f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:2ffbf172-7972-11ec-93d9-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:2ffc1a6c-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:2ffc44ec-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:2ffc6ddc-7972-11ec-93d9-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:2ffcae14-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffcae14-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffcae14-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffcae14-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffcae14-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffcae14-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffcae14-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffd1214-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:2ffd36b8-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2ffd5f94-7972-11ec-93d9-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:2ffda012-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffda012-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffda012-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffda012-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffda012-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffda012-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffda012-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:2ffe057a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:2ffe2a32-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:2ffe532c-7972-11ec-93d9-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:2ffe7c30-7972-11ec-93d9-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:2ffea552-7972-11ec-93d9-0242ac110002 UniProtKB:P00488 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Coagulation factor XIII A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:2ffece60-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:2ffef75a-7972-11ec-93d9-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceruletide is agonist of GPCR (Cholecystokinin receptor type A) DrugCentral uuid:2fff1c26-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:2fff45b6-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:2fff6ed8-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.05']} DrugCentral uuid:2fff97be-7972-11ec-93d9-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrorelix targets GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:2fffbc8a-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrorelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:2fffe700-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:30000ff0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.983']} DrugCentral uuid:300038ea-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:300061c6-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.883']} DrugCentral uuid:30008b2e-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.201']} DrugCentral uuid:3000b554-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3000de58-7972-11ec-93d9-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.93']} DrugCentral uuid:30010752-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.026']} DrugCentral uuid:3001310a-7972-11ec-93d9-0242ac110002 UniProtKB:P14091 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Cathepsin E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.78']} DrugCentral uuid:30015a04-7972-11ec-93d9-0242ac110002 UniProtKB:Q13443 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Disintegrin and metalloproteinase domain-containing protein 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:30018308-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3001ad06-7972-11ec-93d9-0242ac110002 UniProtKB:P62580 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Chloramphenicol acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:3001d66e-7972-11ec-93d9-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:3001ff68-7972-11ec-93d9-0242ac110002 UniProtKB:Q88N29 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Unclassified (Probable HTH-type transcriptional regulator TtgR) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:3002295c-7972-11ec-93d9-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorcyclizine targets Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.22']} DrugCentral uuid:300252d8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.682']} DrugCentral uuid:30027c04-7972-11ec-93d9-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:3002a530-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3002ce3e-7972-11ec-93d9-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:3002f814-7972-11ec-93d9-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:30032136-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:30034a6c-7972-11ec-93d9-0242ac110002 UniProtKB:P21761 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:30037b40-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:30037b40-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:30037b40-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:3003c564-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:3003c564-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:3003c564-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:30040eac-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:30040eac-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:30040eac-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:3004583a-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:3004583a-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:3004583a-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:3004a146-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3004a146-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3004a146-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30051d2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3006109e-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3006109e-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3006109e-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3006109e-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3006109e-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3006109e-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:300679da-7972-11ec-93d9-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:300679da-7972-11ec-93d9-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3006b378-7972-11ec-93d9-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3006b378-7972-11ec-93d9-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3006e9ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:300712f0-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:30073cc6-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:300765e8-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:30078f1e-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3007b82c-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3007e19e-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:30080a98-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3008337e-7972-11ec-93d9-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:30085c82-7972-11ec-93d9-0242ac110002 UniProtKB:O15056 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Synaptojanin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:30088644-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3008af48-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.764']} DrugCentral uuid:3008d860-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:300902ae-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:30092c34-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.163']} DrugCentral uuid:30095ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:30095ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:30095ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:30099854-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroprocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:3009bd2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloropyramine targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3009e656-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:300a0f96-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:300a3912-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:300a62b6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:300a8bd8-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:300ab5e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:300ae01a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:300b0928-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:300b3268-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:300b5b76-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:300b8556-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:300bae64-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:300bd74a-7972-11ec-93d9-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:300c0062-7972-11ec-93d9-0242ac110002 UniProtKB:P05227 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Cytosolic other (Histidine-rich protein PFHRP-II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:300c29ca-7972-11ec-93d9-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:300c530a-7972-11ec-93d9-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:300c7c2c-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:300ca5c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:300ccf06-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N6S8 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Cysteine proteinase falcipain 2a) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:300cf800-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorothiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:300d1cea-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['5.43']} DrugCentral uuid:300d468e-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorotrianisene targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:300d6b78-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorotrianisene is modulator of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:300d903a-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:300db948-7972-11ec-93d9-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:300de2d8-7972-11ec-93d9-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:300e0bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:300e3508-7972-11ec-93d9-0242ac110002 UniProtKB:O15296 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 15-lipoxygenase, type II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:300e5e02-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:300e87ba-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.818']} DrugCentral uuid:300eb0b4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:300edada-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:300f0406-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:300f2ddc-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.967']} DrugCentral uuid:300f5848-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.06']} DrugCentral uuid:300f8156-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:300fb324-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:300fb324-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:300fb324-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:300ff44c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:30101d5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96JM7 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (Lethal(3)malignant brain tumor-like protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:30104654-7972-11ec-93d9-0242ac110002 UniProtKB:Q05BQ5 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (MBT domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:301070b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:301099b0-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.842']} DrugCentral uuid:3010c2d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.975']} DrugCentral uuid:3010eca8-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphentermine is substrate of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.471']} DrugCentral uuid:301115ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphentermine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.404']} DrugCentral uuid:30113eec-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:3011680e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.987']} DrugCentral uuid:3011918a-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:3011baac-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.233']} DrugCentral uuid:3011e3ce-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:30120cfa-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:30123716-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:30126038-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.724']} DrugCentral uuid:30128946-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:3012b344-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3012dcf2-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:30130600-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:30132f36-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3013586c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:30138238-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3013ab50-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3013d472-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3013fec0-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:301429cc-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.553']} DrugCentral uuid:301452e4-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:30147c24-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:3014a5b4-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:3014cee0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3014f7f8-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.759']} DrugCentral uuid:30152250-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:30154c1c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:3015753e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.746']} DrugCentral uuid:30159e42-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.251']} DrugCentral uuid:3015c750-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:3015f3d8-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:30161ce6-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:301645f4-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.827']} DrugCentral uuid:30166f84-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.345']} DrugCentral uuid:3016989c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3016c2ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:3016ebee-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:301715b0-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:30173f5e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.708']} DrugCentral uuid:30176880-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:301791a2-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.092']} DrugCentral uuid:3017bbd2-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:3017ecba-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:3017ecba-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:3017ecba-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:30182e00-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.133']} DrugCentral uuid:30185772-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.928']} DrugCentral uuid:3018808a-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.463']} DrugCentral uuid:3018a9c0-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3018d2ce-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3018fc90-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.061']} DrugCentral uuid:301925a8-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.713']} DrugCentral uuid:30194ea2-7972-11ec-93d9-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.569']} DrugCentral uuid:30197896-7972-11ec-93d9-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3019a208-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:3019cb02-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.043']} DrugCentral uuid:3019f424-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:301a1daa-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.797']} DrugCentral uuid:301a46d6-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.305']} DrugCentral uuid:301a6ff8-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:301a9a0a-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.835']} DrugCentral uuid:301ac3cc-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:301aee1a-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.673']} DrugCentral uuid:301b1746-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.777']} DrugCentral uuid:301b4068-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:301b6c78-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:301b978e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:301bc0ba-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:301bea54-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:301c1376-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:301c3ca2-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:301c65c4-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:301c8f5e-7972-11ec-93d9-0242ac110002 UniProtKB:O35433 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301cb876-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:301ce198-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:301d0a92-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.854']} DrugCentral uuid:301d35b2-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301d76b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:301d76b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:301d76b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:301d76b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:301d76b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:301d76b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:301d76b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:301dff4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301dff4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301dff4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301dff4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301dff4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301dff4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301dff4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:301e81c4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:301e81c4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:301e81c4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:301e81c4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:301e81c4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:301edf0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:301edf0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:301f249e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:301f249e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:301f249e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:301f249e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:301f249e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:301f8722-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:301f8722-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:301f8722-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:301fd06a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:301fd06a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:301fd06a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:30202c36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:30202c36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:30202c36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:30202c36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:30202c36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:30202c36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:30202c36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:30202c36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:3020ab34-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3020d578-7972-11ec-93d9-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3021014c-7972-11ec-93d9-0242ac110002 UniProtKB:P04925 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Unclassified (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:30212a64-7972-11ec-93d9-0242ac110002 UniProtKB:P17405 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Sphingomyelin phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3021537c-7972-11ec-93d9-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:30218108-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:30218108-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:3021b646-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3021df86-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:30220948-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.367']} DrugCentral uuid:30223260-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:30225b96-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:302284c2-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3022aeca-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:3022d7e2-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:302300f0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:302329fe-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:3023537a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:30237d8c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:3023a7e4-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.194']} DrugCentral uuid:3023d124-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:3023fac8-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:302423e0-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.97']} DrugCentral uuid:30244d8e-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:302477a0-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3024a3d8-7972-11ec-93d9-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Surface antigen (Major prion protein) DrugCentral uuid:3024ca16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM07 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Enzyme (Protein-arginine deiminase type-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3024f324-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.56']} DrugCentral uuid:30251cb4-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:30254180-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30256aac-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:302593d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:3025bdae-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:3025e6e4-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:30260ffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3026391e-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:302663c6-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:30268cfc-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:3026b632-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3026df5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:30270902-7972-11ec-93d9-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is activator of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:30273206-7972-11ec-93d9-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:30275b14-7972-11ec-93d9-0242ac110002 UniProtKB:P29475 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:30278580-7972-11ec-93d9-0242ac110002 UniProtKB:P29474 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, endothelial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3027ae84-7972-11ec-93d9-0242ac110002 UniProtKB:P29476 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.554']} DrugCentral uuid:3027d7b0-7972-11ec-93d9-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is activator of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:302800dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is opener of Ion channel (Calcium-activated potassium channel subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.523']} DrugCentral uuid:30282b7a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:30285744-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:30288066-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3028a992-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3028d368-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3028fc8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:302925ca-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:30294eec-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.31']} DrugCentral uuid:30297890-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3029a2de-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3029cc0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3029f630-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:302a1fa2-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:302a496e-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:302a7286-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:302a9c3e-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:302ac52e-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.39']} DrugCentral uuid:302aee5a-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:302b1786-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:302b4102-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:302b6a24-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:302b9436-7972-11ec-93d9-0242ac110002 UniProtKB:O96394 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Arginase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:302bbd4e-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:302be90e-7972-11ec-93d9-0242ac110002 UniProtKB:Q4QEW7 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:302c1226-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:302c3b5c-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:302c653c-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:302c8e36-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:302cb73a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) DrugCentral uuid:302cdbf2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:302d056e-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:302d2e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:302d578a-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:302d808e-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:302daa64-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:302dd372-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:302dfc80-7972-11ec-93d9-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:302e2584-7972-11ec-93d9-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:302e4f3c-7972-11ec-93d9-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:302e785e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:302eb3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:302eb3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:302eb3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:302eb3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:302eb3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:302eb3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:302eb3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:302f1976-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclesonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:302f43a6-7972-11ec-93d9-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:302f6cb4-7972-11ec-93d9-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox is inhibitor of Unclassified (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:302f96e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:302fbfde-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicloprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:302fe8ec-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicloprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:303012e0-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cidofovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:303037b6-7972-11ec-93d9-0242ac110002 UniProtKB:P16444 biolink:molecularly_interacts_with DrugCentral:640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilastatin is inhibitor of Enzyme (Dipeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:303060e2-7972-11ec-93d9-0242ac110002 UniProtKB:P22412 biolink:molecularly_interacts_with DrugCentral:640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilastatin targets Enzyme (Dipeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:303089dc-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilazapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3030b362-7972-11ec-93d9-0242ac110002 UniProtKB:Q02294 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3030e0d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:3030e0d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:30311014-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30313904-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:303163f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:30318ce2-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:3031b60e-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:3031df12-7972-11ec-93d9-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:303208c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:303231ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is inhibitor of Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:30325ac8-7972-11ec-93d9-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:303284b2-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3032adb6-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:3032d6ce-7972-11ec-93d9-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet is positive allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3032ffc8-7972-11ec-93d9-0242ac110002 UniProtKB:P31424 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet is allosteric modulator of GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:30332aac-7972-11ec-93d9-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinalukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:303354dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinalukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) DrugCentral uuid:303379a8-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.035']} DrugCentral uuid:3033a2ca-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:3033cca0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.777']} DrugCentral uuid:3033f5cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:30341eda-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:303447fc-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.552']} DrugCentral uuid:30347164-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.208']} DrugCentral uuid:30349a90-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.987']} DrugCentral uuid:3034c3b2-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.333']} DrugCentral uuid:3034eee6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:30351a2e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:30354364-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.064']} DrugCentral uuid:30356c72-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.849']} DrugCentral uuid:30359620-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:3035bf42-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:3035e85a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:30361172-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:30363b7a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:303664b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.885']} DrugCentral uuid:30368dc8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.242']} DrugCentral uuid:3036b6ea-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.299']} DrugCentral uuid:3036e368-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.793']} DrugCentral uuid:30370fb4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:30373b6a-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.97']} DrugCentral uuid:30376de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:30376de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:30376de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:3037af14-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:3037dc00-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:3037dc00-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:30380bd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:303834c0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AFI2 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:30385dce-7972-11ec-93d9-0242ac110002 UniProtKB:Q45066 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:30388704-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3038b288-7972-11ec-93d9-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3038dc04-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:303904fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303967f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:303a4c06-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:303a4c06-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:303a820c-7972-11ec-93d9-0242ac110002 UniProtKB:P37340 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Unclassified (Multidrug resistance protein mdtK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:303aab1a-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:303ad43c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:303afd2c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:303b26bc-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:303b4fc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.379']} DrugCentral uuid:303b78ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.19']} DrugCentral uuid:303ba1be-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:303bcb30-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:303bf448-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:303c1d60-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:303c47ae-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:303c7102-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.396']} DrugCentral uuid:303c9a10-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:303cc31e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.281']} DrugCentral uuid:303cecea-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:303d1670-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.947']} DrugCentral uuid:303d3f88-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.155']} DrugCentral uuid:303d686e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:303d92c6-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.472']} DrugCentral uuid:303dbbca-7972-11ec-93d9-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:303de4e2-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.063']} DrugCentral uuid:303e0dfa-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:303e3a32-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:303e63ae-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:303e8c94-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:303eb656-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:303edf64-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:303f0872-7972-11ec-93d9-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:303f32ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:303f602e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:303f602e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:303fa494-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:303fa494-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:303fa494-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:303fa494-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:303fa494-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:30400bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:30400bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:30400bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:30400bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:304060aa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:304060aa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:304060aa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:3040ab32-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:3040ab32-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:3040ab32-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:3040ec5a-7972-11ec-93d9-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:30411d38-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:30411d38-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:30411d38-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:30415ee2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.777']} DrugCentral uuid:304187fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3041b11c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.935']} DrugCentral uuid:3041dbe2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:304204e6-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.191']} DrugCentral uuid:30422e08-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.931']} DrugCentral uuid:30425720-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:304280d8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.456']} DrugCentral uuid:3042a9d2-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:3042d2f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:3042fc84-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:3043259c-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:30434e8c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3043779a-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:3043a22e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3043cbdc-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3043f62a-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:30441f42-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:304449cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:304472e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:30449be8-7972-11ec-93d9-0242ac110002 UniProtKB:Q48255 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid targets Enzyme (3-dehydroquinate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3044c528-7972-11ec-93d9-0242ac110002 UniProtKB:P15474 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid targets Enzyme (3-dehydroquinate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3044eefe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EPK8 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid is activator of Ion channel (Transient receptor potential cation channel subfamily V member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:304517da-7972-11ec-93d9-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:30453ca6-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.441']} DrugCentral uuid:304565a0-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:30458fda-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:3045b8de-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:668 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clarithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:3045e1ec-7972-11ec-93d9-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'MPC', 'has_quantitative_value': ['8.719']} DrugCentral uuid:30460b86-7972-11ec-93d9-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.187']} DrugCentral uuid:3046349e-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:30465da2-7972-11ec-93d9-0242ac110002 UniProtKB:Q59401 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3046869c-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:3046afdc-7972-11ec-93d9-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3046d8ea-7972-11ec-93d9-0242ac110002 UniProtKB:P13661 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase OXA-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:304701f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:30472ae8-7972-11ec-93d9-0242ac110002 UniProtKB:A4KCT8 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:304754b4-7972-11ec-93d9-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:30477dae-7972-11ec-93d9-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3047a6d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:3047cfc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9F663 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Carbepenem-hydrolyzing beta-lactamase KPC) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3047f9a0-7972-11ec-93d9-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:304822ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:30484bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD64 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:30487628-7972-11ec-93d9-0242ac110002 UniProtKB:Q6GWS8 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:30489f2c-7972-11ec-93d9-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3048c844-7972-11ec-93d9-0242ac110002 UniProtKB:A0ZX81 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:3048f134-7972-11ec-93d9-0242ac110002 UniProtKB:Q4TVR4 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:30491b8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:304944a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q2XPY6 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:30496db2-7972-11ec-93d9-0242ac110002 UniProtKB:P0A3M1 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:304996d4-7972-11ec-93d9-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3049c096-7972-11ec-93d9-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3049eb3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q670S6 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:304a1438-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:304a3d50-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:304a66d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:304a8ff8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:304ab91a-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:304ae228-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:304b0db6-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:304b36e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:304b600e-7972-11ec-93d9-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:304b91aa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:304b91aa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:304b91aa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:304bdaa2-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:304bdaa2-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:304bdaa2-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:304c1c06-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.115']} DrugCentral uuid:304c46ae-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:304c6fc6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:304c98e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:304cc386-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:304ced16-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.514']} DrugCentral uuid:304d164c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.036']} DrugCentral uuid:304d3f82-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:304d6958-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:304d928e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:304dbbba-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:304de4dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.604']} DrugCentral uuid:304e0e76-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:304e3798-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:304e60a6-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:304e89c8-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.703']} DrugCentral uuid:304eb506-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.084']} DrugCentral uuid:304ede28-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.558']} DrugCentral uuid:304f0740-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:304f30f8-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:304f5a42-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.269']} DrugCentral uuid:304f8350-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:304fada8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:304fd72e-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:305000d2-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:305029c2-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:305053c0-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:30507f8a-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:3050a99c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3050d2aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3050fbc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.396']} DrugCentral uuid:3051257a-7972-11ec-93d9-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:30514e88-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN4 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:30517764-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3051a0e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13507 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:3051c9c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y210 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3051f2ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:30521bec-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:30524680-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:30527150-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:30529a4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3052c380-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:674 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clevidipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:3052e8ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:674 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clevidipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:30530db8-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:3053328e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:30535bb0-7972-11ec-93d9-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clindamycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:305380d6-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3053a9f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:3053d31a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:3053fc46-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:30542e64-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:30542e64-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:30542e64-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:30546942-7972-11ec-93d9-0242ac110002 UniProtKB:P05141 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (ADP/ATP translocase 2) DrugCentral uuid:30548e0e-7972-11ec-93d9-0242ac110002 UniProtKB:P12235 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Transporter (ADP/ATP translocase 1) DrugCentral uuid:3054b370-7972-11ec-93d9-0242ac110002 UniProtKB:P12236 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (ADP/ATP translocase 3) DrugCentral uuid:3054d828-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) DrugCentral uuid:3054fcfe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT1 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid is inhibitor of Transporter (Solute carrier family 17 member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:30552616-7972-11ec-93d9-0242ac110002 UniProtKB:B1LRJ1 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Unclassified (Type IV secretion-like conjugative transfer relaxase protein TraI) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:30554f9c-7972-11ec-93d9-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:3055758a-7972-11ec-93d9-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:30559eb6-7972-11ec-93d9-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3055c7a6-7972-11ec-93d9-0242ac110002 UniProtKB:P60891 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Ribose-phosphate pyrophosphokinase 1) DrugCentral uuid:3055eda8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HA47 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Uridine-cytidine kinase 1) DrugCentral uuid:30561454-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BZX2 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Uridine-cytidine kinase 2) DrugCentral uuid:3056393e-7972-11ec-93d9-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3056621a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L2G3 biolink:molecularly_interacts_with DrugCentral:692 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofazimine targets Enzyme (Uncharacterized oxidoreductase CzcO-like) DrugCentral uuid:305687ea-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:692 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofazimine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3056b134-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3056da42-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3057031e-7972-11ec-93d9-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Enzyme (Lipoprotein lipase) DrugCentral uuid:3057283a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:30575166-7972-11ec-93d9-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:30577a74-7972-11ec-93d9-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clometacin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3057a396-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.461']} DrugCentral uuid:3057cd94-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.455']} DrugCentral uuid:3057f6b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:30581fb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.745']} DrugCentral uuid:305848be-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:305873de-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:30589ce2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:3058c5f0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.025']} DrugCentral uuid:3058ef08-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.062']} DrugCentral uuid:30591898-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:305941c4-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:30596adc-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.142']} DrugCentral uuid:3059955c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:3059beb0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.187']} DrugCentral uuid:3059e7be-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.407']} DrugCentral uuid:305a10b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.889']} DrugCentral uuid:305a3a84-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.358']} DrugCentral uuid:305a637e-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:305a8c78-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.896']} DrugCentral uuid:305ab586-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.371']} DrugCentral uuid:305adeee-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.668']} DrugCentral uuid:305b07fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.206']} DrugCentral uuid:305b30f6-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:305b5b12-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.519']} DrugCentral uuid:305b851a-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:305baeaa-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.979']} DrugCentral uuid:305bd790-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:305c0152-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.778']} DrugCentral uuid:305c2a2e-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:305c531e-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:305c7d08-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:305ca670-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:305ccf88-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:305cf8aa-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:305d21ae-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:305d4ba2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:305d749c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.243']} DrugCentral uuid:305d9dbe-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.703']} DrugCentral uuid:305dc6ea-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:305df084-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:305e199c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:305e42a0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:305e6bb8-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:305e953e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:305ebe56-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:305ee746-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.412']} DrugCentral uuid:305f119e-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.007']} DrugCentral uuid:305f3d9a-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.696']} DrugCentral uuid:305f66b2-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:305f8fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:305fb978-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:305fe268-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:30600b80-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3060345c-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.319']} DrugCentral uuid:30605da6-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:306087ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:3060b0c6-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:3060d9de-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:30610684-7972-11ec-93d9-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Glutathione S-transferase P) DrugCentral uuid:30612c4a-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:3061553a-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3061803c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:3061a972-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.937']} DrugCentral uuid:3061d320-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:3061fc2e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:306225a0-7972-11ec-93d9-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:30624eb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:306277c6-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3062d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3063a6fa-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3063a6fa-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3063a6fa-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3063a6fa-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3063fc68-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3063fc68-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3063fc68-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3064456a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:3064456a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:3064456a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:306486ce-7972-11ec-93d9-0242ac110002 UniProtKB:P39051 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3064b0d6-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:3064e1be-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:3064e1be-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:3064e1be-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30655c66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:30664ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:30664ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:30664ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:30664ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:30664ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:30664ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3066f42c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3067d3d8-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3067fe3a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3068273e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:30685402-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:30687d9c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3068a6a0-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3068d008-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3068f920-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3069222e-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:30694b28-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:306974ae-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:30699dd0-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:3069c6f2-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3069f000-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:306a1b52-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.41']} DrugCentral uuid:306a4500-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:306a6e04-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:306a971c-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:306ac098-7972-11ec-93d9-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:306ae9ba-7972-11ec-93d9-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:306b12d2-7972-11ec-93d9-0242ac110002 UniProtKB:O88703 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:306b3ce4-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.796']} DrugCentral uuid:306b6656-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:306b9716-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:306b9716-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:306b9716-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:306bd870-7972-11ec-93d9-0242ac110002 UniProtKB:O70507 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:306c0476-7972-11ec-93d9-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:306c2d84-7972-11ec-93d9-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonixin targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:306c5692-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloperastine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:306c8018-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.524']} DrugCentral uuid:306ca930-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel is antagonist of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:306cd266-7972-11ec-93d9-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel targets Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:306d0358-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:306d0358-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:306d0358-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:306d4cd2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:306d4cd2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:306d4cd2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:306d8fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:306d8fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:306d8fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:306dd314-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:306dd314-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:306dd314-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:306e0cee-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.825']} DrugCentral uuid:306e362e-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:306e6090-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:306e89c6-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:306eb2e8-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:306eebd2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:306eebd2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:306eebd2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:306eebd2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:306eebd2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:306f4d34-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:306f4d34-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:306f4d34-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:306f903c-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.186']} DrugCentral uuid:306fbb34-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.379']} DrugCentral uuid:306fe442-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:30700d3c-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.136']} DrugCentral uuid:307036c2-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:30705fee-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.391']} DrugCentral uuid:30708910-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:3070b2aa-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.351']} DrugCentral uuid:3070dc3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3071053e-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:30712e42-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.174']} DrugCentral uuid:30715746-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.514']} DrugCentral uuid:30718338-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.104']} DrugCentral uuid:3071ac50-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.995']} DrugCentral uuid:3071d676-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:30720006-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.132']} DrugCentral uuid:3072293c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3072525e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.235']} DrugCentral uuid:30727b94-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.429']} DrugCentral uuid:3072a646-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.046']} DrugCentral uuid:3072cf86-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.466']} DrugCentral uuid:3072f8bc-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.294']} DrugCentral uuid:307321de-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:30734d30-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.287']} DrugCentral uuid:30737648-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.677']} DrugCentral uuid:30739f60-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.785']} DrugCentral uuid:3073c882-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:3073f21c-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.267']} DrugCentral uuid:30741b3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:30744456-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.106']} DrugCentral uuid:30746dfa-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:30749726-7972-11ec-93d9-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:3074c034-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:3074e4ec-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.156']} DrugCentral uuid:30750f26-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.521']} DrugCentral uuid:30753848-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.132']} DrugCentral uuid:30756174-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.598']} DrugCentral uuid:30758aa0-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:3075afda-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:3075d910-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3076032c-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.712']} DrugCentral uuid:30762c58-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:307655b6-7972-11ec-93d9-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.645']} DrugCentral uuid:30767f46-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3076a854-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:3076d176-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.159']} DrugCentral uuid:3076fd18-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:30772626-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.058']} DrugCentral uuid:30774f34-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.089']} DrugCentral uuid:307778b0-7972-11ec-93d9-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3077a1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:3077caf4-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.497']} DrugCentral uuid:3077f402-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.178']} DrugCentral uuid:30781d56-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.854']} DrugCentral uuid:30784650-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:30786f5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:307899a2-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3078c530-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.471']} DrugCentral uuid:3078ee52-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.112']} DrugCentral uuid:30791774-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.906']} DrugCentral uuid:307940aa-7972-11ec-93d9-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:30796a26-7972-11ec-93d9-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:30799334-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.942']} DrugCentral uuid:3079bc56-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:3079e5b4-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:307a0fd0-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:307a38e8-7972-11ec-93d9-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:307a620a-7972-11ec-93d9-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:307a8be0-7972-11ec-93d9-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.99']} DrugCentral uuid:307ab50c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:307ade1a-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:307b073c-7972-11ec-93d9-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:307b30d6-7972-11ec-93d9-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:307b59e4-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPN5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Putative cytochrome P450 130) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:307b82fc-7972-11ec-93d9-0242ac110002 UniProtKB:P00766 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Alpha-chymotrypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:307bac0a-7972-11ec-93d9-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:307bd66c-7972-11ec-93d9-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:307bff8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:307c2888-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:307c4d40-7972-11ec-93d9-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:307c7720-7972-11ec-93d9-0242ac110002 UniProtKB:A4ZYU9 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:307ca042-7972-11ec-93d9-0242ac110002 UniProtKB:Q3S5C3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Transporter (Efflux transporter; SugE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:307cc946-7972-11ec-93d9-0242ac110002 UniProtKB:Q48435 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:307cf22c-7972-11ec-93d9-0242ac110002 UniProtKB:P62594 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:307d2b52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:307d2b52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:307d2b52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:307d2b52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:307d2b52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:307d7abc-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxazolam targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:307da44c-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:307dcd5a-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.783']} DrugCentral uuid:307df758-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:307e2084-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:307e4c58-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.154']} DrugCentral uuid:307e7570-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:307e9e56-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:307ec7d2-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:307ef0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:307f19ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:307f4324-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:307f6c96-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:307f95ae-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:307fbed0-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:307fe7de-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.78']} DrugCentral uuid:308011d2-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:30803ae0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3080640c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:30808d1a-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.594']} DrugCentral uuid:3080b6f0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:3080dff4-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:308108f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:308131fc-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.181']} DrugCentral uuid:30815b78-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:30818472-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.591']} DrugCentral uuid:3081ad6c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:3081d742-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.792']} DrugCentral uuid:308201ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.356']} DrugCentral uuid:30822abc-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:308253d4-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:30827d82-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:3082a726-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:3082d00c-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3082f924-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:30832296-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:30834b9a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:308374a8-7972-11ec-93d9-0242ac110002 UniProtKB:P22310 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (UDP-glucuronosyltransferase 1-4) {'has_attribute_type': 'IAO:0000004', 'name': 'app Km', 'has_quantitative_value': ['4.208']} DrugCentral uuid:30839da2-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3083c94e-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3083f27a-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:30841b7e-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.445']} DrugCentral uuid:30844662-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:30846f8e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:308498a6-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3084c1aa-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:3084eb12-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:30851416-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:30853d06-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:3085661e-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3085901c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3085b916-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3085e21a-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:30860b32-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:308635e4-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:30865ef2-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:30868800-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3086b104-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3086da80-7972-11ec-93d9-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3087035c-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:30872c74-7972-11ec-93d9-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3087567c-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:30878296-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:3087ac30-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:3087d548-7972-11ec-93d9-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3087fef6-7972-11ec-93d9-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:30882818-7972-11ec-93d9-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:30885112-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:30887a2a-7972-11ec-93d9-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:3088a3c4-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:3088cdb8-7972-11ec-93d9-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3088f6d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:30891fca-7972-11ec-93d9-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:30894c16-7972-11ec-93d9-0242ac110002 UniProtKB:Q91ZY2 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:30897560-7972-11ec-93d9-0242ac110002 UniProtKB:Q91ZY1 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3089a242-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3089a242-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3089e734-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3089e734-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3089e734-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3089e734-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3089e734-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:308a4e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:308a4e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:308a4e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:308a4e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:308aa3ea-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:308aa3ea-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:308aa3ea-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:308ae90e-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:308ae90e-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:308b30ee-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:308b30ee-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:308b30ee-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:308b30ee-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:308b30ee-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:308b91ce-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:308b91ce-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:308b91ce-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:308bee6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:308bee6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:308bee6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:308bee6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:308bee6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:308bee6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:308bee6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:308bee6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:308c754e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:308c754e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:308c754e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:308cb6b2-7972-11ec-93d9-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:308ce092-7972-11ec-93d9-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:308d098c-7972-11ec-93d9-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.21']} DrugCentral uuid:308d32a4-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP23 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Cytosolic other (Calmodulin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:308d5ba8-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:308d80f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:308da9fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:308dd312-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:308dfd60-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:308e26e6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:308e5008-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.67']} DrugCentral uuid:308e7902-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:308ea242-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:308ecee8-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:308ef800-7972-11ec-93d9-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:308f2104-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UI33 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel protein type 11 subunit alpha) DrugCentral uuid:308f467a-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:308f6f7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:308f9454-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:308fbd6c-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:308fe6fc-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:3090101e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:30903a44-7972-11ec-93d9-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3090633e-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:30909138-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:30909138-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3090ceaa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:3090ceaa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:3090ceaa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:30910fbe-7972-11ec-93d9-0242ac110002 UniProtKB:P27922 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:30913994-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GJT6 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:309162c0-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:30918bf6-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:3091b590-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:3091ea38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3091ea38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3091ea38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3091ea38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3092370e-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:30926116-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.801']} DrugCentral uuid:30928a1a-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:3092aedc-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.49']} DrugCentral uuid:3092d7c2-7972-11ec-93d9-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.194']} DrugCentral uuid:30930148-7972-11ec-93d9-0242ac110002 UniProtKB:P07437 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine is inhibitor of Structural (Tubulin beta chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:30932a6a-7972-11ec-93d9-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:30935378-7972-11ec-93d9-0242ac110002 UniProtKB:P02550 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:30937db2-7972-11ec-93d9-0242ac110002 UniProtKB:Q6B856 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin beta-2B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3093a792-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine is inhibitor of Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3093d1a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q27957 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Unclassified (Tubulin polymerization-promoting protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3093fac6-7972-11ec-93d9-0242ac110002 UniProtKB:P68371 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin beta-4B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:30942d02-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:30942d02-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:30942d02-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:30947762-7972-11ec-93d9-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:30947762-7972-11ec-93d9-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3094acaa-7972-11ec-93d9-0242ac110002 UniProtKB:Q08828 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Enzyme (Adenylate cyclase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:3094ddec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:3094ddec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:3094ddec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:30951f3c-7972-11ec-93d9-0242ac110002 UniProtKB:P11166 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Transporter (Solute carrier family 2, facilitated glucose transporter member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3095485e-7972-11ec-93d9-0242ac110002 UniProtKB:P19754 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Enzyme (Adenylate cyclase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3095723e-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:30959b9c-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:3095c4d2-7972-11ec-93d9-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:3095edd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:30961a4a-7972-11ec-93d9-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:3096438a-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:30966cac-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Cytosolic other (Annexin A1) DrugCentral uuid:30969182-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3096bb44-7972-11ec-93d9-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:3096e466-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:30970e14-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:30973baa-7972-11ec-93d9-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:30973baa-7972-11ec-93d9-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:3097721e-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortivazol is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:309796e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cotinine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:3097bbac-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:3097e64a-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:30980f58-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3098385c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:30986174-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:30988ad2-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:3098b3fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3098dd20-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3099080e-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:30993130-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:30995a48-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:30998360-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:3099adc2-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3099d6ee-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:3099fffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:309a291e-7972-11ec-93d9-0242ac110002 UniProtKB:Q33BM1 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G protein-coupled receptor GPR35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:309a5290-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES90 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:309a7b9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:309aa4d4-7972-11ec-93d9-0242ac110002 UniProtKB:P25815 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets Cytosolic other (Protein S100-P) DrugCentral uuid:309ac982-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:309af362-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.237']} DrugCentral uuid:309b1c8e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:309b45ec-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:309b7008-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:309b9a06-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:309bc300-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.602']} DrugCentral uuid:309bec18-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:309c159e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:309c3ec0-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:309c67e2-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:309c90fa-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:309cbabc-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.531']} DrugCentral uuid:309ce3f2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.235']} DrugCentral uuid:309d0d28-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:309d365e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.623']} DrugCentral uuid:309d60de-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:309d8a0a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.993']} DrugCentral uuid:309db3a4-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.353']} DrugCentral uuid:309ddcda-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:309e066a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.385']} DrugCentral uuid:309e2f96-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.799']} DrugCentral uuid:309e58b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.924']} DrugCentral uuid:309e81e4-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.342']} DrugCentral uuid:309eabd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:309ed4fa-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.206']} DrugCentral uuid:309eff2a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:309f2950-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:309f4e26-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:309f7856-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.728']} DrugCentral uuid:309fa150-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:309fcaae-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:309ff3d0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.541']} DrugCentral uuid:30a01ce8-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.812']} DrugCentral uuid:30a04614-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:30a06fcc-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:30a098f8-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:30a0c1fc-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.829']} DrugCentral uuid:30a0eb14-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:30a114cc-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:30a13dc6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.222']} DrugCentral uuid:30a166a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.509']} DrugCentral uuid:30a18fb0-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:30a1b940-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclofenil targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:30a1e258-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclofenil targets Nuclear other (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:30a20b98-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:30a23578-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:30a25eb8-7972-11ec-93d9-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:30a287d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:30a2b0de-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:30a2dac8-7972-11ec-93d9-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:30a303fe-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:30a32d2a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclopentolate is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:30a351e2-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclophosphamide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:30a37c26-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a3a52a-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:30a3ce42-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a3f746-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a420ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:30a44a20-7972-11ec-93d9-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a4732e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WQA8 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Enzyme (Alanine racemase) DrugCentral uuid:30a497d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q05586 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:30a4c1a8-7972-11ec-93d9-0242ac110002 UniProtKB:O60391 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a4ebd8-7972-11ec-93d9-0242ac110002 UniProtKB:P9WP31 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine is inhibitor of Enzyme (D-alanine--D-alanine ligase) DrugCentral uuid:30a510d6-7972-11ec-93d9-0242ac110002 UniProtKB:P9WQA9 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine is inhibitor of Enzyme (Alanine racemase) DrugCentral uuid:30a535a2-7972-11ec-93d9-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:30a55f6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:30a59f74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a59f74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a59f74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a59f74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a59f74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a59f74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a59f74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30a61184-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:30a63aa6-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:30a663aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:30a68e0c-7972-11ec-93d9-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:30a6b706-7972-11ec-93d9-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:30a6e028-7972-11ec-93d9-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is modulator of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:30a70a26-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:30a733f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:30a75d00-7972-11ec-93d9-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:30a785fa-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:30a7af94-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:30a7d8ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q02790 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:30a801c4-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:30a82adc-7972-11ec-93d9-0242ac110002 UniProtKB:P23284 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.01']} DrugCentral uuid:30a85520-7972-11ec-93d9-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:30a87e38-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:30a8a764-7972-11ec-93d9-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:30a8d072-7972-11ec-93d9-0242ac110002 UniProtKB:Q08752 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:30a8fa3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:30a92356-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:30a94c78-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:30a9759a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHG7 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:30a99f2a-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:30a9c400-7972-11ec-93d9-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:30a9ed18-7972-11ec-93d9-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:30aa161c-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is allosteric modulator of Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:30aa41e6-7972-11ec-93d9-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is allosteric modulator of Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:30aa77a6-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:30aa77a6-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:30aa77a6-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:30aa77a6-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:30aac742-7972-11ec-93d9-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:30aaf050-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:30ab19b8-7972-11ec-93d9-0242ac110002 UniProtKB:P05412 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Transcription factor (Transcription factor AP-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:30ab42d0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycrimine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:30ab67e2-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:30ab90fa-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:30abba12-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:30abe334-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.855']} DrugCentral uuid:30ac0e0e-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:30ac32da-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:30ac5be8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:30ac8500-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:30acae72-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.419']} DrugCentral uuid:30acd7bc-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.812']} DrugCentral uuid:30ad00c0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.652']} DrugCentral uuid:30ad29e2-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:30ad535e-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:30ad7c6c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:30ada598-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:30add068-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:30adfb88-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.222']} DrugCentral uuid:30ae24b4-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:30ae4db8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.185']} DrugCentral uuid:30ae7734-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:30aea024-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:30aec93c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:30aef330-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:30af1cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.559']} DrugCentral uuid:30af45ba-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:30af6ee6-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.733']} DrugCentral uuid:30af97f4-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:30afc51c-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:30aff5c8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:30aff5c8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:30aff5c8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:30b030ce-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:30b05a68-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.899']} DrugCentral uuid:30b083b2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:30b0ad4c-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:30b0d6d2-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:30b0ffcc-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:30b128ee-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:30b15206-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:30b17cea-7972-11ec-93d9-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:30b1a602-7972-11ec-93d9-0242ac110002 UniProtKB:P34968 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:30b1cf42-7972-11ec-93d9-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:30b1f86e-7972-11ec-93d9-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:30b221f4-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:30b25a3e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:30b25a3e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:30b25a3e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:30b25a3e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:30b25a3e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:30b2c456-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:30b2c456-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:30b2c456-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:30b2c456-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:30b2c456-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:30b32586-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:30b32586-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:30b32586-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:30b37144-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:30b37144-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:30b37144-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:30b3b262-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTS6 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Enzyme (Histone-lysine N-methyltransferase SETD7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:30b3db7a-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.053']} DrugCentral uuid:30b40582-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:30b42eae-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:30b457a8-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.678']} DrugCentral uuid:30b4823c-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:30b4ab7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.315']} DrugCentral uuid:30b4d49e-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:30b4fdca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:769 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cysteine targets Transporter (Cystine/glutamate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:30b528ae-7972-11ec-93d9-0242ac110002 UniProtKB:P15309 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (Prostatic acid phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'GI50', 'has_quantitative_value': ['7']} DrugCentral uuid:30b5523e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:30b57b24-7972-11ec-93d9-0242ac110002 UniProtKB:P06746 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (DNA polymerase beta) DrugCentral uuid:30b5a798-7972-11ec-93d9-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:30b5a798-7972-11ec-93d9-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:30b5a798-7972-11ec-93d9-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:30b5e316-7972-11ec-93d9-0242ac110002 UniProtKB:Q00987 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Nuclear other (E3 ubiquitin-protein ligase Mdm2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:30b60c1a-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacarbazine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.255']} DrugCentral uuid:30b63528-7972-11ec-93d9-0242ac110002 UniProtKB:Q14181 biolink:molecularly_interacts_with DrugCentral:773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacarbazine targets Enzyme (DNA polymerase alpha subunit B) DrugCentral uuid:30b65a6c-7972-11ec-93d9-0242ac110002 UniProtKB:P62993 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Cytosolic other (Growth factor receptor-bound protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:30b68370-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:30b6ac92-7972-11ec-93d9-0242ac110002 UniProtKB:Q60631 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Cytosolic other (Growth factor receptor-bound protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:30b6d604-7972-11ec-93d9-0242ac110002 UniProtKB:Q96IV0 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Enzyme (Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.05']} DrugCentral uuid:30b7021e-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:30b72b4a-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:30b75494-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:30b77dac-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:30b7a75a-7972-11ec-93d9-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:30b7d086-7972-11ec-93d9-0242ac110002 UniProtKB:P04070 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Vitamin K-dependent protein C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:30b7f9bc-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:30b822f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:30b84ca0-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:30b87d56-7972-11ec-93d9-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:30b87d56-7972-11ec-93d9-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:30b87d56-7972-11ec-93d9-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:30b8be88-7972-11ec-93d9-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:30b8eb7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q28731 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Unclassified (Thrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:30b91518-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.243']} DrugCentral uuid:30b93e26-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:30b96a36-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.163']} DrugCentral uuid:30b9945c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.087']} DrugCentral uuid:30b9bd6a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.248']} DrugCentral uuid:30b9e68c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:30ba11ac-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.976']} DrugCentral uuid:30ba3ac4-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:30ba63d2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.425']} DrugCentral uuid:30ba8cea-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.708']} DrugCentral uuid:30bab972-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.894']} DrugCentral uuid:30bae29e-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.462']} DrugCentral uuid:30bb0bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.265']} DrugCentral uuid:30bb3532-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:30bb5e9a-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.207']} DrugCentral uuid:30bb87c6-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.294']} DrugCentral uuid:30bbb0e8-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:30bbd636-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:30bbfaee-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:30bc23de-7972-11ec-93d9-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Enzyme (Steryl-sulfatase) DrugCentral uuid:30bc4882-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:30bc72bc-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.053']} DrugCentral uuid:30bc9bd4-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:30bcc578-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:30bcee9a-7972-11ec-93d9-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene is antagonist of Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.757']} DrugCentral uuid:30bd182a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15413 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene is antagonist of Ion channel (Ryanodine receptor 3) DrugCentral uuid:30bd3cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:30bd65fa-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.929']} DrugCentral uuid:30bd8f26-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.762']} DrugCentral uuid:30bdb99c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:30bde2be-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.485']} DrugCentral uuid:30be0bea-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole is antagonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:30be30ac-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.279']} DrugCentral uuid:30be5ce4-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.388']} DrugCentral uuid:30be866a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:30beab2c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:30bed44e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:30befdc0-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:30bf26ec-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:30bf4ff0-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:30bf7912-7972-11ec-93d9-0242ac110002 UniProtKB:P0C0X1 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone is inhibitor of Enzyme (Dihydropteroate synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:30bfa252-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:30bfcb60-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:30bff43c-7972-11ec-93d9-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:30c01b88-7972-11ec-93d9-0242ac110002 UniProtKB:Q4Z710 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Unclassified (Dihydropteroate synthetase, putative) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:30c047a2-7972-11ec-93d9-0242ac110002 UniProtKB:A0A113T0T6 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:30c07114-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:30c099fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q57P83 biolink:molecularly_interacts_with DrugCentral:783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daptomycin targets Transporter (Outer membrane porin protein OmpD) DrugCentral uuid:30c0bef8-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:30c0e7fc-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:30c11114-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:30c13a0e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:30c1636c-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:30c18c8e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:30c1b5a6-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:30c1dfa4-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:30c209de-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:30c232f6-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:30c25bfa-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:30c28544-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:30c2aeca-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.6']} DrugCentral uuid:30c2d7e2-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:30c30172-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:30c32b02-7972-11ec-93d9-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:30c353fc-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Breakpoint cluster region protein) DrugCentral uuid:30c378c8-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:30c3a1f4-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:30c3cc56-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:30c3f582-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.1']} DrugCentral uuid:30c41eae-7972-11ec-93d9-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.07']} DrugCentral uuid:30c4479e-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:30c47110-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:30c49a14-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:30c4c318-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:30c4ec1c-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:30c51598-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:30c53e7e-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:30c5678c-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.33']} DrugCentral uuid:30c5907c-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:30c5baf2-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:30c5e4fa-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.46']} DrugCentral uuid:30c60e30-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:30c638f6-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:30c661fa-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:30c68b1c-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:30c6b42a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:30c6dd9c-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:30c706aa-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:30c72fcc-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:30c758da-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:30c78382-7972-11ec-93d9-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:30c7ac9a-7972-11ec-93d9-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:30c7d58a-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:30c7fea2-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:30c8281e-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.77']} DrugCentral uuid:30c85136-7972-11ec-93d9-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:30c87a3a-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:30c8a3c0-7972-11ec-93d9-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:30c8ccba-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:30c8f5c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:30c91ecc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:30c9494c-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:30c972be-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:30c99c4e-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:30c9c552-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:30c9efaa-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.03']} DrugCentral uuid:30ca18ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:30ca41da-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.51']} DrugCentral uuid:30ca6ad4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:30ca9464-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:30cabd72-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.59']} DrugCentral uuid:30cae694-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:30cb0f98-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.35']} DrugCentral uuid:30cb39c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:30cb62cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.25']} DrugCentral uuid:30cb8bd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:30cbb560-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.16']} DrugCentral uuid:30cbde6e-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.47']} DrugCentral uuid:30cc0772-7972-11ec-93d9-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:30cc308a-7972-11ec-93d9-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:30cc5b46-7972-11ec-93d9-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:30cc845e-7972-11ec-93d9-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:30ccad6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:30ccd6ac-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:30cd00be-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:30cd29c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:30cd52d0-7972-11ec-93d9-0242ac110002 UniProtKB:P06240 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase LCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.19']} DrugCentral uuid:30cd7bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:30cda550-7972-11ec-93d9-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:30cdce5e-7972-11ec-93d9-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.41']} DrugCentral uuid:30cdf884-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:30ce21f6-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:30ce4afa-7972-11ec-93d9-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:30ce7408-7972-11ec-93d9-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:30ce9d16-7972-11ec-93d9-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:30cec78c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:30cef090-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.68']} DrugCentral uuid:30cf1980-7972-11ec-93d9-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:30cf4266-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:30cf6bd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:30cf94e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:30cfbdf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:30cfe702-7972-11ec-93d9-0242ac110002 UniProtKB:P27037 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:30d0107e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:30d03996-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:30d06358-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:30d08c5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:30d0b6c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:30d0e102-7972-11ec-93d9-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:30d10a2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:30d133b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99640 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:30d15cb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:30d185bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:30d1aeca-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:30d1d83c-7972-11ec-93d9-0242ac110002 UniProtKB:P36894 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bone morphogenetic protein receptor type-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:30d20230-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:30d22b52-7972-11ec-93d9-0242ac110002 UniProtKB:Q5VT25 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:30d25442-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:30d28142-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:30d2aae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:30d2d412-7972-11ec-93d9-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:30d2fd02-7972-11ec-93d9-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:30d32688-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:30d34fa0-7972-11ec-93d9-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.16']} DrugCentral uuid:30d378b8-7972-11ec-93d9-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:30d3a234-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:30d3cb74-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:30d3f478-7972-11ec-93d9-0242ac110002 UniProtKB:P16277 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:30d41d86-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.41']} DrugCentral uuid:30d4478e-7972-11ec-93d9-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:30d4709c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:30d499a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:30d4c2b8-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:30d4ec0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:30d5152e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:30d53e32-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:30d56740-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:30d590d0-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:30d5b9d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:30d5e2d8-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30d60ce0-7972-11ec-93d9-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:30d63756-7972-11ec-93d9-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:30d6606e-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:30d6899a-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:30d6b32a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:30d6dc2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:30d7055a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:30d72f1c-7972-11ec-93d9-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:30d7640a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:30d7640a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:30d7640a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:30d7640a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:30d7b4f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase; MEK1/2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:30d7b4f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase; MEK1/2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:30d7efce-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:30d7efce-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:30d82a7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01538 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Transcription factor (Myelin transcription factor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:30d8537e-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:30d87868-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:30d89d84-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:30d8c232-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:30d8e6e0-7972-11ec-93d9-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:30d90b98-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:30d934f6-7972-11ec-93d9-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:30d95dd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deanol targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:30d986f4-7972-11ec-93d9-0242ac110002 UniProtKB:P28570 biolink:molecularly_interacts_with DrugCentral:787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deanol targets Transporter (Creatine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:30d9b0de-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:788 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 debrisoquine targets Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:30d9d8d4-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:788 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 debrisoquine targets Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:30d9ffa8-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:30da288e-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:30da5188-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:30da7b04-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:30daa80e-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:30daa80e-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:30daec74-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:30daec74-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:30daec74-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:30daec74-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:30daec74-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:30db3bac-7972-11ec-93d9-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decitabine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:30db64ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decitabine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:30db8990-7972-11ec-93d9-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferoxamine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:30dbb3ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferoxamine targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:30dbdcc4-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:30dc05d2-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.84']} DrugCentral uuid:30dc2f6c-7972-11ec-93d9-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:30dc587a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GRG7 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:30dc8192-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.921']} DrugCentral uuid:30dcaaa0-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.97']} DrugCentral uuid:30dcd412-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.276']} DrugCentral uuid:30dcfd16-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:30dd25fc-7972-11ec-93d9-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:30dd4f32-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:30dd7a52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:30dda482-7972-11ec-93d9-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:30ddd5d8-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:30ddd5d8-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:30ddd5d8-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30de506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:30df2e6a-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demecarium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:30df553e-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:30df7a00-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:30df9f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:30dfc906-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denopamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:30dff26e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denopamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:30e01b86-7972-11ec-93d9-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deptropine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:30e044bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WSF8 biolink:molecularly_interacts_with DrugCentral:808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deptropine targets Unclassified (Soluble acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:30e07608-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:30e07608-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:30e07608-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:30e0b74e-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deserpidine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:30e0dc38-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:30e1010e-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:30e12788-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:30e14c5e-7972-11ec-93d9-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:30e17134-7972-11ec-93d9-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:30e19b14-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:30e19b14-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e20400-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:30e2c7e6-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:30e2f2a2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.631']} DrugCentral uuid:30e31bb0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:30e344c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:30e36de0-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.755']} DrugCentral uuid:30e3977a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.081']} DrugCentral uuid:30e3c0a6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.194']} DrugCentral uuid:30e3e9e6-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:30e4131c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:30e43d10-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:30e46614-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:30e48f2c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:30e4b3ee-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:30e4dfae-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:30e508d0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:30e53260-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:30e55bdc-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:30e584f4-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:30e5adf8-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:30e5d724-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:30e601b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:30e62684-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:30e64f74-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.6']} DrugCentral uuid:30e67882-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:30e6a3c0-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:30e6ccc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:30e6f5f0-7972-11ec-93d9-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:30e71eea-7972-11ec-93d9-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:30e7485c-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:30e7717e-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e7cc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:30e89f0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:30e89f0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:30e89f0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:30e8e07c-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:30e90a02-7972-11ec-93d9-0242ac110002 UniProtKB:P48545 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:30e93400-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:30e977e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:30e977e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:30e977e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:30e977e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:30e977e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:30e977e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:30e977e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:30e977e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:30e9e7ba-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:30ea10aa-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:30ea3b52-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.956']} DrugCentral uuid:30ea64d8-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.025']} DrugCentral uuid:30ea8dfa-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:30eab71c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:30eae0ac-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:30eb09d8-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.009']} DrugCentral uuid:30eb32f0-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.189']} DrugCentral uuid:30eb5c26-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:30eb85a2-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.967']} DrugCentral uuid:30ebaf50-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:30ebd854-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:30ec0158-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:30ec2d9a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:30ec568a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:30ec7f98-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:30eca914-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.511']} DrugCentral uuid:30ecd33a-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:30ecfc5c-7972-11ec-93d9-0242ac110002 UniProtKB:O75899 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets GPCR (Gamma-aminobutyric acid type B receptor subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.027']} DrugCentral uuid:30ed2556-7972-11ec-93d9-0242ac110002 UniProtKB:P28476 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-2) DrugCentral uuid:30ed521a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:30ed521a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:30ed521a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30edc8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:30eea192-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:30eecad2-7972-11ec-93d9-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:30eef412-7972-11ec-93d9-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:30ef1da2-7972-11ec-93d9-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:30ef4796-7972-11ec-93d9-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:30ef70cc-7972-11ec-93d9-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:30ef99f8-7972-11ec-93d9-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:30efc590-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin is agonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:30efeec6-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desogestrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:30f0139c-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desogestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:30f03cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.932']} DrugCentral uuid:30f06680-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone targets Cytosolic other (Annexin A1) DrugCentral uuid:30f08b7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:30f0b48c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:30f0dda4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.498']} DrugCentral uuid:30f1072a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:30f13042-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:30f1596e-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11']} DrugCentral uuid:30f1827c-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:30f1acde-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:30f1d61e-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycorticosterone acetate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) DrugCentral uuid:30f1fafe-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycorticosterone pivalate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:30f2247a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.886']} DrugCentral uuid:30f24dc4-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.88']} DrugCentral uuid:30f276c8-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytosolic other (Annexin A1) DrugCentral uuid:30f29b94-7972-11ec-93d9-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:30f2c524-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:30f2ee28-7972-11ec-93d9-0242ac110002 UniProtKB:P05112 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytokine (Interleukin-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:30f317a4-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:30f340d0-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:30f36c5e-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.786']} DrugCentral uuid:30f39594-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:30f3beac-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.517']} DrugCentral uuid:30f3e7d8-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:30f411a4-7972-11ec-93d9-0242ac110002 UniProtKB:O54915 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:30f43be8-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:30f460d2-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:30f489fe-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:30f4b370-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:30f4dc88-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:30f505a0-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:30f52ea4-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:30f5599c-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:30f582aa-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:30f5abb8-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:30f5d548-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:30f5fe60-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:30f62796-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:30f650c2-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:30f67a2a-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:30f6a34c-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:30f6cc50-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:30f6f572-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexbrompheniramine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:30f71b6a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:30f74590-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:30f77e02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:30f77e02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:30f77e02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:30f77e02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:30f77e02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:30f7d816-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:30f80142-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:30f82a6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:30f853ea-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:30f87d0c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:30f8a642-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.607']} DrugCentral uuid:30f8cf6e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.384']} DrugCentral uuid:30f8fbc4-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:30f924dc-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.042']} DrugCentral uuid:30f94ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.257']} DrugCentral uuid:30f97900-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:30f9a358-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:30f9cc8e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.733']} DrugCentral uuid:30f9f5b0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.577']} DrugCentral uuid:30fa1f2c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.326']} DrugCentral uuid:30fa4830-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.156']} DrugCentral uuid:30fa7152-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:30fa9a88-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.898']} DrugCentral uuid:30fac5d0-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.706']} DrugCentral uuid:30faefd8-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:30fb190e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:30fb424e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:30fb6c06-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:30fb951e-7972-11ec-93d9-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexloxiglumide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:30fbbe5e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:30fbe7c6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:30fc1106-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:30fc3a46-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:30fc6368-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:30fc8de8-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:30fcb8a4-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:30fce1c6-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:30fd127c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:30fd127c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:30fd127c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:30fd5c46-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:30fd5c46-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:30fd5c46-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:30fd9dbe-7972-11ec-93d9-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:30fdc726-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:30fdec10-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:30fe1546-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:30fe3e54-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:30fe789c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:30fe789c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:30fe789c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:30fe789c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:30fe789c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:30fed422-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:30fefde4-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:30ff271a-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:30ff5046-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:30ff7968-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:30ffa316-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:30ffcc4c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:30fff58c-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:31001eae-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.824']} DrugCentral uuid:3100496a-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:310072aa-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:31009be0-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:3100c50c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:3100ef5a-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:31011890-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:3101496e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3101496e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3101496e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:31018fbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:31018fbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:3101bf20-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:3101e40a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:31020f8e-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:310238c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:310261fa-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:310286ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3102b0e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:3102d5c2-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:3102ff02-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:310323ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.87']} DrugCentral uuid:31034d36-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:31037658-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:31039f5c-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:3103c888-7972-11ec-93d9-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3103f290-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:31041b8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:310476ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:31053f06-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is agonist of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'D2', 'has_quantitative_value': ['6.458']} DrugCentral uuid:310567ec-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.842']} DrugCentral uuid:31059104-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ks', 'has_quantitative_value': ['4.48']} DrugCentral uuid:3105bb16-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:3105e424-7972-11ec-93d9-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is blocker of Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:31060d28-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:3106362c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:31065fe4-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:31069fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:31069fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:31069fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:31069fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:31069fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:31069fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:31069fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:310719ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:310719ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:310719ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:31075b38-7972-11ec-93d9-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:31078662-7972-11ec-93d9-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3107b128-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:3107d5fe-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:3107fab6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:310824fa-7972-11ec-93d9-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:3108531c-7972-11ec-93d9-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor) DrugCentral uuid:3108531c-7972-11ec-93d9-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor) DrugCentral uuid:3108994e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3108994e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3108994e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3108994e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3108994e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3108994e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3108994e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:31090b4a-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dezocine is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:31093458-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dezocine is antagonist of GPCR (Kappa-type opioid receptor) DrugCentral uuid:31095a64-7972-11ec-93d9-0242ac110002 UniProtKB:P42574 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (Caspase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:310983e0-7972-11ec-93d9-0242ac110002 UniProtKB:P55210 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (Caspase-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:3109acbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q17339 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Unclassified (Female germline-specific tumor suppressor gld-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3109d5b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q02083 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (N-acylethanolamine-hydrolyzing acid amidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:310a06b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:310a06b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:310a06b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:310a47da-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:310a70de-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:310a9a78-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is allosteric modulator of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:310ac386-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:310aece4-7972-11ec-93d9-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:310b1674-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:310b4374-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:310b6ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:310b97de-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:310bc0ce-7972-11ec-93d9-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.67']} DrugCentral uuid:310bea4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:310c1344-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:310c3c48-7972-11ec-93d9-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:310c6614-7972-11ec-93d9-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:310c8f2c-7972-11ec-93d9-0242ac110002 UniProtKB:P19969 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:310cbff6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:310cbff6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:310cbff6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:310d09ac-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:310d09ac-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:310d09ac-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:310d53da-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:310d53da-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:310d53da-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:310d9d40-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:310d9d40-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:310d9d40-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:310de64c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:310de64c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:310de64c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:310e3084-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:310e3084-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:310e3084-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310eab5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:310f9ece-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:310f9ece-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:310f9ece-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:310f9ece-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:310f9ece-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:310f9ece-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:31100da0-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:31100da0-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:31100da0-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:311057ec-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:311057ec-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:311057ec-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:3110a0ee-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3110a0ee-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3110a0ee-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:31111830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:3111f386-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3111f386-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3111f386-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:31123ca6-7972-11ec-93d9-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:31123ca6-7972-11ec-93d9-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:31123ca6-7972-11ec-93d9-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:31128698-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:31128698-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:31128698-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:3112cf54-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:3112cf54-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:3112cf54-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:31131892-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:31131892-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:31131892-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:31136220-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:31136220-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:31136220-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:3113a4a6-7972-11ec-93d9-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide targets Enzyme (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.64']} DrugCentral uuid:3113d20a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is opener of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:3113d20a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is opener of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:3114072a-7972-11ec-93d9-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is activator of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:3114302e-7972-11ec-93d9-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibekacin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.921']} DrugCentral uuid:31145b08-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:31147fca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:3114ac34-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3114ac34-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3114ac34-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3114edc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3115170a-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazone is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.081']} DrugCentral uuid:31154018-7972-11ec-93d9-0242ac110002 UniProtKB:Q15118 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3']} DrugCentral uuid:3115699e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15119 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.699']} DrugCentral uuid:31159306-7972-11ec-93d9-0242ac110002 UniProtKB:Q15120 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.097']} DrugCentral uuid:3115bc28-7972-11ec-93d9-0242ac110002 UniProtKB:Q16654 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.301']} DrugCentral uuid:3115e540-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:31160e62-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:31163996-7972-11ec-93d9-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:311664b6-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:31168dd8-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:3116b6e6-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:3116e0a8-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:311709b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:311732e2-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:31175bfa-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:31178558-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:3117ae7a-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.577']} DrugCentral uuid:3117d788-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.423']} DrugCentral uuid:311802ee-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:31182c24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:31185550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:31187e5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3118a82a-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3118d142-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:3118fae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:3119253e-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:31194ece-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:31197804-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:3119a126-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3119ca52-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3119f662-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:311a1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:311a489c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:311a727c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:311a9b9e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:311ac4ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:311aedc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:311b1736-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:311b4062-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:311b697a-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:311b9274-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:311bbe02-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:311be760-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is antagonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:311c117c-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:311c3a8a-7972-11ec-93d9-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:311c644c-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:311c8d3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:311cb64a-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:311cdfd0-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:311d08c0-7972-11ec-93d9-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:311d31ce-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:311d5b04-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:311d8516-7972-11ec-93d9-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:311dae1a-7972-11ec-93d9-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:311dd732-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAW7 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:311e0054-7972-11ec-93d9-0242ac110002 UniProtKB:P19224 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:311e2a16-7972-11ec-93d9-0242ac110002 UniProtKB:O60656 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:311e5338-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAW8 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:311e7cdc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:311ea5e0-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:311ecf34-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:311ef838-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:311f211e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:311f4b44-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:311f74fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:311f99b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:311fc290-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:311fec2a-7972-11ec-93d9-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:31201600-7972-11ec-93d9-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:31204e2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:31204e2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:31204e2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:31204e2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:31204e2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:31209d64-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.971']} DrugCentral uuid:3120c668-7972-11ec-93d9-0242ac110002 UniProtKB:P15559 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (NAD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3120ef9e-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.388']} DrugCentral uuid:3121188e-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.354']} DrugCentral uuid:31214372-7972-11ec-93d9-0242ac110002 UniProtKB:Q16549 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Proprotein convertase subtilisin/kexin type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:31216c8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:312195ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:3121bf14-7972-11ec-93d9-0242ac110002 UniProtKB:P07374 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Urease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3121e818-7972-11ec-93d9-0242ac110002 UniProtKB:P9WMN1 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (ATP phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:3122111c-7972-11ec-93d9-0242ac110002 UniProtKB:P05982 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (NULLD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:31223a3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.509']} DrugCentral uuid:312263a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.686']} DrugCentral uuid:31228cbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.773']} DrugCentral uuid:3122b5cc-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:3122dee4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.082']} DrugCentral uuid:31230a0e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:312334f2-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:31235e00-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.386']} DrugCentral uuid:3123870e-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:3123b0f8-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.079']} DrugCentral uuid:3123db00-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3124042c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.033']} DrugCentral uuid:31242d44-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.386']} DrugCentral uuid:312456c0-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.767']} DrugCentral uuid:3124806e-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.327']} DrugCentral uuid:3124a972-7972-11ec-93d9-0242ac110002 UniProtKB:P70676 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Unclassified (SMR1-alpha2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:3124d46a-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:3124fd82-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.61']} DrugCentral uuid:31252e56-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:31252e56-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:31252e56-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:31257046-7972-11ec-93d9-0242ac110002 UniProtKB:Q72549 biolink:molecularly_interacts_with DrugCentral:869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 didanosine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:31259972-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dienestrol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:3125c294-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dienogest is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:3125e760-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:312610a0-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:31263558-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:31265e02-7972-11ec-93d9-0242ac110002 UniProtKB:E1G1C3 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine is positive modulator of Ion channel (Nematode GABA-A receptor) DrugCentral uuid:31265e02-7972-11ec-93d9-0242ac110002 UniProtKB:E1G1C3 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine is positive modulator of Ion channel (Nematode GABA-A receptor) DrugCentral uuid:31268d78-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylpropion is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:3126b35c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylpropion is inhibitor of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:3126d828-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.316']} DrugCentral uuid:31270140-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.894']} DrugCentral uuid:31272a62-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.252']} DrugCentral uuid:312753de-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:31277cf6-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:3127a73a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:3127d048-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:3127fa28-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.276']} DrugCentral uuid:3128235e-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.178']} DrugCentral uuid:31284c58-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.439']} DrugCentral uuid:3128761a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:3128a11c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:3128ca48-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.575']} DrugCentral uuid:3128f356-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.223']} DrugCentral uuid:31291cc8-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.272']} DrugCentral uuid:312945cc-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:31296eee-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.437']} DrugCentral uuid:312997e8-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.408']} DrugCentral uuid:3129c222-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.317']} DrugCentral uuid:3129eb3a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.657']} DrugCentral uuid:312a1452-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:312a3d56-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.778']} DrugCentral uuid:312a6862-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:312a917a-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:312aba74-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.274']} DrugCentral uuid:312ae396-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.739']} DrugCentral uuid:312b0d4e-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:312b367a-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.019']} DrugCentral uuid:312b5fb0-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.593']} DrugCentral uuid:312b8990-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:312bb3ac-7972-11ec-93d9-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Estrogen-related receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:312bdcc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:312c05d2-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.983']} DrugCentral uuid:312c30e8-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.847']} DrugCentral uuid:312c5a5a-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.361']} DrugCentral uuid:312c8368-7972-11ec-93d9-0242ac110002 UniProtKB:O95718 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Steroid hormone receptor ERR2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:312cac6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.483']} DrugCentral uuid:312cd5ca-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:312cfeec-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:312d27e6-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.528']} DrugCentral uuid:312d50cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.052']} DrugCentral uuid:312d7aac-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.214']} DrugCentral uuid:312da3b0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:312dccbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:312df6c6-7972-11ec-93d9-0242ac110002 UniProtKB:O08580 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:312e2042-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 difenoxin is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:312e450e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:312e6e30-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:312e9798-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:312ec0b0-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd1', 'has_quantitative_value': ['7.125']} DrugCentral uuid:312ee9be-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:312f12e0-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:312f3cac-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:312f65e2-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.648']} DrugCentral uuid:312f8ed2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.857']} DrugCentral uuid:312fb966-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:312fdf2c-7972-11ec-93d9-0242ac110002 UniProtKB:P50997 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31300844-7972-11ec-93d9-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:31304c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31304c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31304c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31304c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31304c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31304c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31304c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31304c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3130cb08-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.783']} DrugCentral uuid:3130f402-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.136']} DrugCentral uuid:31311dce-7972-11ec-93d9-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:313146be-7972-11ec-93d9-0242ac110002 UniProtKB:P50997 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:31316fb8-7972-11ec-93d9-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:3131b540-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3131b540-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3131b540-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3131b540-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3131b540-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3131b540-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3131b540-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3131b540-7972-11ec-93d9-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:313232cc-7972-11ec-93d9-0242ac110002 UniProtKB:P51450 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:31325c3e-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.007']} DrugCentral uuid:31328560-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:3132ae82-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.187']} DrugCentral uuid:3132d83a-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.526']} DrugCentral uuid:31330152-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:31332a88-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:313353aa-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:31337d4e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.085']} DrugCentral uuid:3133a666-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.114']} DrugCentral uuid:3133cf74-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.121']} DrugCentral uuid:3133f896-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:31342212-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:31344b20-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.728']} DrugCentral uuid:3134744c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.261']} DrugCentral uuid:31349d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.369']} DrugCentral uuid:3134c730-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:3134f03e-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31351aa0-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.299']} DrugCentral uuid:31354444-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:313570cc-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:313599f8-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydrocodeine is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:3135beba-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.087']} DrugCentral uuid:3135e840-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.462']} DrugCentral uuid:31361176-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:31363bb0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.309']} DrugCentral uuid:313664c8-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.127']} DrugCentral uuid:31368ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:3136b7b6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.385']} DrugCentral uuid:3136e0ec-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.373']} DrugCentral uuid:31370a18-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.377']} DrugCentral uuid:3137347a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.903']} DrugCentral uuid:31375da6-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:313786be-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:3137ab94-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.442']} DrugCentral uuid:3137d510-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:3137fe46-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.605']} DrugCentral uuid:3138275e-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1D) DrugCentral uuid:31384c2a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:31387600-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.183']} DrugCentral uuid:31389f22-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:3138c3da-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:3138ecfc-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:313916fa-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.896']} DrugCentral uuid:3139401c-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:31396934-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.79']} DrugCentral uuid:31399292-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.14']} DrugCentral uuid:3139bb96-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3139e4b8-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.804']} DrugCentral uuid:313a0e02-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.922']} DrugCentral uuid:313a37ce-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.529']} DrugCentral uuid:313a61f4-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.412']} DrugCentral uuid:313a8b20-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:313ab438-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.424']} DrugCentral uuid:313ae0b6-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.644']} DrugCentral uuid:313b09d8-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.364']} DrugCentral uuid:313b3386-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:313b5cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.83']} DrugCentral uuid:313b864c-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:313baf64-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:313bd430-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.752']} DrugCentral uuid:313bfde8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.742']} DrugCentral uuid:313c2714-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:313c504a-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:313c796c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.821']} DrugCentral uuid:313ca3ce-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.69']} DrugCentral uuid:313ccd68-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:313cf234-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 5A) DrugCentral uuid:313d16f6-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:313d4072-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:313d69a8-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.349']} DrugCentral uuid:313d92d4-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.416']} DrugCentral uuid:313dbbd8-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:313de568-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.18']} DrugCentral uuid:313e0e6c-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:313e3784-7972-11ec-93d9-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:313e607e-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:313e8b44-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:313eb466-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:313edd88-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:313f0e8e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:313f0e8e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:313f0e8e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:313f4fca-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:313f7464-7972-11ec-93d9-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:313f9912-7972-11ec-93d9-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:313fbe2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:313fe2d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:3140078a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:31402c42-7972-11ec-93d9-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:31405ed8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:31405ed8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:31405ed8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3140a172-7972-11ec-93d9-0242ac110002 UniProtKB:O54699 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Transporter (Equilibrative nucleoside transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3140ca4e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:3140efd8-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:3141149a-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:3141393e-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:31415df6-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:3141877c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:3141b094-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.736']} DrugCentral uuid:3141d984-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:31420300-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:31422cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:314256f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3142800a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:3142a904-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.017']} DrugCentral uuid:3142d2e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3142fbfc-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:31432500-7972-11ec-93d9-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:31434e18-7972-11ec-93d9-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:3143778a-7972-11ec-93d9-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:3143a084-7972-11ec-93d9-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3143d158-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:3143d158-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:3143d158-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:31441d16-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:31441d16-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:31441d16-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:31445e48-7972-11ec-93d9-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3144876a-7972-11ec-93d9-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:3144b12c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JIS7 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3144da44-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimemorfan is inhibitor of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:31450352-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.791']} DrugCentral uuid:31452cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.312']} DrugCentral uuid:314555dc-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.695']} DrugCentral uuid:31457ef4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.703']} DrugCentral uuid:3145a816-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3145d2e6-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.479']} DrugCentral uuid:3145fd5c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:3146269c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:31464fd2-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:31467980-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.785']} DrugCentral uuid:3146a2a2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:3146cbc4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:3146f4e6-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.644']} DrugCentral uuid:31471e6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.749']} DrugCentral uuid:3147477a-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.821']} DrugCentral uuid:3147707e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:31479a9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q7KQK5 biolink:molecularly_interacts_with DrugCentral:902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetacrine targets Unclassified (Apical membrane antigen 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:3147c402-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:3147ed9c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:314816d2-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:31484080-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3148698e-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:314892a6-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3148c384-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:3148c384-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:3148c384-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:31490902-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:31490902-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:31493850-7972-11ec-93d9-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxyline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:31496168-7972-11ec-93d9-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxyline targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:31498d28-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3149b618-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3149df26-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:314a08ca-7972-11ec-93d9-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:314a31d8-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:314a5ad2-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:314a83e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:314aada2-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:314ad6b0-7972-11ec-93d9-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:314affc8-7972-11ec-93d9-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:314b28d6-7972-11ec-93d9-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:314b53f6-7972-11ec-93d9-0242ac110002 UniProtKB:P43117 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:314b7d0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:314ba784-7972-11ec-93d9-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:314bd088-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:314bfa54-7972-11ec-93d9-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:314c2330-7972-11ec-93d9-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:314c4c52-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:314c7560-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:314c9efa-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:314cc808-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:314cf102-7972-11ec-93d9-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:314d1b00-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:314d4422-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:314d6d3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:314d9742-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:314dc0f0-7972-11ec-93d9-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:314de9e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:314e12ee-7972-11ec-93d9-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:314e3be8-7972-11ec-93d9-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:314e6564-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:314e8e68-7972-11ec-93d9-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:314eb7f8-7972-11ec-93d9-0242ac110002 UniProtKB:P43117 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:314ee0f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:314f0abe-7972-11ec-93d9-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:314f33f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:314f5d02-7972-11ec-93d9-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:314f86a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:314faf96-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:314fd890-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:315001b2-7972-11ec-93d9-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:31502ade-7972-11ec-93d9-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:315053ec-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphemanil is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:315078ae-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphemanil is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:31509d5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3150c7aa-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.018']} DrugCentral uuid:3150f0b8-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:315119da-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:315142e8-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:31516caa-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.81']} DrugCentral uuid:315196c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:3151c100-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3151ea0e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:31521380-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:31523c98-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:315265ba-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.585']} DrugCentral uuid:31528edc-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.932']} DrugCentral uuid:3152ba88-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3152e396-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.678']} DrugCentral uuid:3153144c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3153144c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3153144c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3153565a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:31537f72-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.658']} DrugCentral uuid:3153a89e-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:918 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenoxylate is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.167']} DrugCentral uuid:3153d22e-7972-11ec-93d9-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:918 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenoxylate targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3153fb46-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.076']} DrugCentral uuid:3154244a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:31544d62-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.377']} DrugCentral uuid:3154774c-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:31549c22-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3154c530-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:3154e9fc-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:31550fea-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:315534b6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:31555978-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:31557f20-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:3155a478-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:3155cda4-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3155f6da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:31562006-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:31564a2c-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.802']} DrugCentral uuid:3156734e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:31569c8e-7972-11ec-93d9-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3156c5b0-7972-11ec-93d9-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3156ef4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 7B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3157186c-7972-11ec-93d9-0242ac110002 UniProtKB:O60658 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:31574170-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.158']} DrugCentral uuid:31576bbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:31579558-7972-11ec-93d9-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3157c276-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:3157c276-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:3157fb9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3157fb9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3158461a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3158461a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3158461a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3158461a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3158461a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3158461a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3158b4b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:3158b4b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:3158b4b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:3158f600-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:31591f2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q86TP1 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Protein prune homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3159483a-7972-11ec-93d9-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:315971d4-7972-11ec-93d9-0242ac110002 UniProtKB:P0DTD1 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:31599b00-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:3159bfc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.036']} DrugCentral uuid:3159e9e8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:315a131e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:315a37ea-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:315a5c98-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:315a818c-7972-11ec-93d9-0242ac110002 UniProtKB:P48544 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:315aaaae-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:315ad39e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.604']} DrugCentral uuid:315afd1a-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 distigmine is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:315b229a-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:315b4bb2-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.846']} DrugCentral uuid:315b74ca-7972-11ec-93d9-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Translocator protein) DrugCentral uuid:315b9996-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.967']} DrugCentral uuid:315bc402-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.115']} DrugCentral uuid:315bed10-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.735']} DrugCentral uuid:315c1632-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.156']} DrugCentral uuid:315c3f54-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.658']} DrugCentral uuid:315c69fc-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.129']} DrugCentral uuid:315c9404-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.833']} DrugCentral uuid:315cbd30-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.434']} DrugCentral uuid:315ce648-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.434']} DrugCentral uuid:315d1014-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:315d3936-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.957']} DrugCentral uuid:315d6280-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:315d8bac-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:315db5a0-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.862']} DrugCentral uuid:315ddec2-7972-11ec-93d9-0242ac110002 UniProtKB:P05091 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram is inhibitor of Enzyme (Aldehyde dehydrogenase, mitochondrial) DrugCentral uuid:315e03a2-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.319']} DrugCentral uuid:315e2d0a-7972-11ec-93d9-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.738']} DrugCentral uuid:315e5636-7972-11ec-93d9-0242ac110002 UniProtKB:P25025 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-X-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:315e7f6c-7972-11ec-93d9-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:315ea8a2-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.821']} DrugCentral uuid:315ed1f6-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.794']} DrugCentral uuid:315efb18-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.669']} DrugCentral uuid:315f2444-7972-11ec-93d9-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.357']} DrugCentral uuid:315f4d70-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.333']} DrugCentral uuid:315f789a-7972-11ec-93d9-0242ac110002 UniProtKB:P11884 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Aldehyde dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:315fa428-7972-11ec-93d9-0242ac110002 UniProtKB:Q99685 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:315fcd40-7972-11ec-93d9-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:315ff662-7972-11ec-93d9-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:31602024-7972-11ec-93d9-0242ac110002 UniProtKB:P29375 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysine-specific demethylase 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:31604946-7972-11ec-93d9-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:31607272-7972-11ec-93d9-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:31609c84-7972-11ec-93d9-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3160c6b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3160efd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:316118ee-7972-11ec-93d9-0242ac110002 UniProtKB:P57764 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Unclassified (Gasdermin-D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:316142ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9VTU8 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 2, isoform A; LD26647p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:31616c0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9V396 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 1; GH09688p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:31619530-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3161be20-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3161e7d8-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:316210d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:316239ea-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:31626366-7972-11ec-93d9-0242ac110002 UniProtKB:P05181 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Cytochrome P450 2E1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:31628e22-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3162b758-7972-11ec-93d9-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:3162e05c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:3163094c-7972-11ec-93d9-0242ac110002 UniProtKB:P57764 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Unclassified (Gasdermin-D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3163349e-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:31635d8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R4D5 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:31638692-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R455 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:3163b040-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:3163d94e-7972-11ec-93d9-0242ac110002 UniProtKB:Q7Z2W7 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:31640234-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:31642b38-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:31645496-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.976']} DrugCentral uuid:31647da4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:3164a6a8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3164d092-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:3164fcb6-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.771']} DrugCentral uuid:316525d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:31654ec8-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:316577ea-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:3165a1a2-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3165caba-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3165f3d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:31661d4e-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:31664666-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.256']} DrugCentral uuid:31666f60-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:31669864-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3166c2da-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3166ec38-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.258']} DrugCentral uuid:3167153c-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.401']} DrugCentral uuid:31673e36-7972-11ec-93d9-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.301']} DrugCentral uuid:3167680c-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3167912e-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:3167ba64-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3167e390-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:31680d02-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.223']} DrugCentral uuid:31683606-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:31685f28-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:31688836-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3168b360-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:3168dd86-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:316906a8-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:31693042-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:316954fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:316979b2-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.086']} DrugCentral uuid:3169a2c0-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.283']} DrugCentral uuid:3169cc32-7972-11ec-93d9-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets GPCR (Growth hormone-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a13ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:316a9e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316af198-7972-11ec-93d9-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:316b8aea-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:316bb47a-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide targets Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:316bd932-7972-11ec-93d9-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:316c024a-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.766']} DrugCentral uuid:316c2b9e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:316c57ea-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.988']} DrugCentral uuid:316c80f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:316caa06-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:316cd04e-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:316cfa06-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.586']} DrugCentral uuid:316d231e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:316d4c54-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:316d75f8-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:316d9f06-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:316dc828-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.013']} DrugCentral uuid:316df14a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:316e1b34-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:316e444c-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:316e6d50-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:316e965e-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:316ec034-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:316ee960-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:316f128c-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.553']} DrugCentral uuid:316f43a6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:316f43a6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:316f43a6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:316f7e84-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:316fa7b0-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:316fd0e6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:316ffaee-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:31702424-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.93']} DrugCentral uuid:31704d46-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3170764a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3170a020-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:3170c91a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:3170f228-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:31711b90-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3171448a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.046']} DrugCentral uuid:31716e10-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3171971e-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3171c14e-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3171ea48-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:31721338-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:31723c28-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:317265b8-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:31728e94-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:3172b8c4-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:3172e1c8-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:31730b3a-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:31733466-7972-11ec-93d9-0242ac110002 UniProtKB:P32738 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Choline O-acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:31735d56-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3173874a-7972-11ec-93d9-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3173b120-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3173da38-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:31740382-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:31742d26-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:31745620-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.19']} DrugCentral uuid:31747f42-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3174a864-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3174d1e0-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.18']} DrugCentral uuid:3174fac6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.084']} DrugCentral uuid:317523e8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:31754d00-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:31757834-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3175a142-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3175ca50-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.375']} DrugCentral uuid:3175f354-7972-11ec-93d9-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:31761d20-7972-11ec-93d9-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:3176462e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:31766f3c-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:317698cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3176c1da-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:3176eade-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:317713e2-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:31773e44-7972-11ec-93d9-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3177677a-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:31779074-7972-11ec-93d9-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:3177ba54-7972-11ec-93d9-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3177e470-7972-11ec-93d9-0242ac110002 UniProtKB:P09172 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Dopamine beta-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3']} DrugCentral uuid:317818f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:317818f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:317818f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:317818f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:31786df0-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:31786df0-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:31786df0-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3178b45e-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:3178b45e-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:3178f888-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3178f888-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3178f888-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3178f888-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3178f888-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:31795b0c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:31795b0c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:31795b0c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:3179b796-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3179b796-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3179b796-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3179b796-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3179b796-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3179b796-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3179b796-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3179b796-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:317a35c2-7972-11ec-93d9-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:317a5f34-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:317a881a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8I2J3 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (M18 aspartyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:317ab100-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopexamine targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:317ad5c2-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopexamine targets GPCR (D(1A) dopamine receptor) DrugCentral uuid:317afdae-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:317b2734-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:317b5056-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:317b7a2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:317ba344-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:317bcc52-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:317bf560-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:317c1ec8-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:317c47cc-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:317c70b2-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:317c99c0-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:317cc382-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:317cedc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:317d16f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:317d4028-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:317d69e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:317d92f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:317dbc24-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:317de53c-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:317e0ee0-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:317e38fc-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:317e6232-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:317e8d20-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:317eb6ec-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:317ee004-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:317f0930-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:317f3310-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:317f5c3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:317f8568-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:317fae80-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:317fd7f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:31800128-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31802a54-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.066']} DrugCentral uuid:31805376-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.337']} DrugCentral uuid:3180801c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.588']} DrugCentral uuid:3180ac72-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.378']} DrugCentral uuid:3180d5ee-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:3180ff9c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:318128a0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.744']} DrugCentral uuid:318151b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:31817ac6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3181a44c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:3181cd64-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:3181f672-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.275']} DrugCentral uuid:31821f80-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:31824aaa-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram is blocker of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:31826f80-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram is blocker of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:3182942e-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:3182bd3c-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:3182e708-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:31831160-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:31833a78-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:318363ae-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.845']} DrugCentral uuid:31838d20-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.631']} DrugCentral uuid:3183b638-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:3183df5a-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:318409bc-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:31843310-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.827']} DrugCentral uuid:31845c32-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:3184854a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3184afac-7972-11ec-93d9-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3184d8a6-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.381']} DrugCentral uuid:318501be-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.81']} DrugCentral uuid:31852ac2-7972-11ec-93d9-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3185542a-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:31857d06-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3185a628-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3185cf36-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:3185fa56-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:31862364-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.53']} DrugCentral uuid:31864d58-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:3186771a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:31869ff6-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3186c8e6-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3186f1e0-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:31871b3e-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 7) DrugCentral uuid:31873ff6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.629']} DrugCentral uuid:3187690e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3187921c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.325']} DrugCentral uuid:3187bcec-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:3187e8c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:31881192-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:31883aaa-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:31886444-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:31888d48-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:3188b642-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:3188df50-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:318908d6-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:31893342-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:31895c3c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:3189866c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11']} DrugCentral uuid:3189affc-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.886']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318a0a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:318ad2f6-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:318afc0e-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:957 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxercalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:318b20c6-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxifluridine targets Enzyme (Thymidylate synthase) DrugCentral uuid:318b4592-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:318b703a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:318b9952-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.433']} DrugCentral uuid:318bc260-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:318be74a-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:318c1184-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:318c3632-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:318c5ad6-7972-11ec-93d9-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:318c7f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.914']} DrugCentral uuid:318ca8d8-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.496']} DrugCentral uuid:318cd1fa-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.288']} DrugCentral uuid:318cfaf4-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.605']} DrugCentral uuid:318d240c-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:318d4e00-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:318d77f4-7972-11ec-93d9-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:318da0ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:318dcaba-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:318df508-7972-11ec-93d9-0242ac110002 UniProtKB:P61823 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Ribonuclease pancreatic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:318e1e0c-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.867']} DrugCentral uuid:318e4724-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.805']} DrugCentral uuid:318e70a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:318e999a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:318ec2b2-7972-11ec-93d9-0242ac110002 UniProtKB:P43870 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (Type-2 restriction enzyme HindIII) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:318eebb6-7972-11ec-93d9-0242ac110002 UniProtKB:O52691 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (Type-2 restriction enzyme ScaI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:318f1726-7972-11ec-93d9-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:318f407a-7972-11ec-93d9-0242ac110002 UniProtKB:P9WIQ1 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (UDP-galactopyranose mutase) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:318f697e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:318f9282-7972-11ec-93d9-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:318fb7ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:318fe0fc-7972-11ec-93d9-0242ac110002 UniProtKB:P08254 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Enzyme (Stromelysin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:31900a00-7972-11ec-93d9-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:31903322-7972-11ec-93d9-0242ac110002 UniProtKB:P45452 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Collagenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:31905c9e-7972-11ec-93d9-0242ac110002 UniProtKB:P02980 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Transporter (Tetracycline resistance protein, class B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:319085a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:31910414-7972-11ec-93d9-0242ac110002 UniProtKB:P09237 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Matrilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.14']} DrugCentral uuid:319133ee-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxylamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:319158d8-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drostanolone propionate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:31917e30-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.199']} DrugCentral uuid:3191a75c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:3191d088-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.602']} DrugCentral uuid:3191fb08-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:31922506-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:31924e14-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:319277fe-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.132']} DrugCentral uuid:3192a12a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.069']} DrugCentral uuid:3192cc72-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.623']} DrugCentral uuid:3192f59e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.996']} DrugCentral uuid:31931eca-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.027']} DrugCentral uuid:3193485a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3193717c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:31939a94-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.782']} DrugCentral uuid:3193c3a2-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.592']} DrugCentral uuid:3193ed14-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.076']} DrugCentral uuid:3194162c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.175']} DrugCentral uuid:31943f4e-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:31946992-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.695']} DrugCentral uuid:319493e0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.78']} DrugCentral uuid:3194bcda-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3194eda4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:3194eda4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:3194eda4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:31952fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.5']} DrugCentral uuid:319558b6-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:319581ce-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.5']} DrugCentral uuid:3195aac8-7972-11ec-93d9-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drotaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:3195d0ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drotaverine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:3195f55a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:31963cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:3196bdd2-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3196e6f4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:319710e8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:319739ec-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:3197630e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:31978c6c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:3197b58e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3197de9c-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3198078c-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:319831e4-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:31985b38-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.402']} DrugCentral uuid:31988428-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:3198ad36-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3198d7d4-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.352']} DrugCentral uuid:319900ec-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.428']} DrugCentral uuid:31992a7c-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.09']} DrugCentral uuid:319954f2-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:31997f4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3199a86c-7972-11ec-93d9-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3199d170-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3199fa74-7972-11ec-93d9-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:319a24cc-7972-11ec-93d9-0242ac110002 UniProtKB:P18405 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:319a4dc6-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dyclonine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:319a76ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dyclonine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:319a9c4a-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dydrogesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:319ac56c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dydrogesterone targets Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.561']} DrugCentral uuid:319aee7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprophylline is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) DrugCentral uuid:319b1346-7972-11ec-93d9-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprophylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:319b3858-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:319b6148-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:319b8a4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.506']} DrugCentral uuid:319bb350-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:319bddc6-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:319c0706-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:319c3014-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:319c5922-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:319c82e4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.588']} DrugCentral uuid:319cabf2-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.701']} DrugCentral uuid:319cd50a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.905']} DrugCentral uuid:319cfe2c-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:319d27bc-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.472']} DrugCentral uuid:319d50d4-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.384']} DrugCentral uuid:319d79c4-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.543']} DrugCentral uuid:319da3c2-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:319dcdc0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.554']} DrugCentral uuid:319df6d8-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:319e1fdc-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.937']} DrugCentral uuid:319e49a8-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.615']} DrugCentral uuid:319e72ac-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.719']} DrugCentral uuid:319e9bba-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.397']} DrugCentral uuid:319ec554-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.106']} DrugCentral uuid:319eeed0-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.743']} DrugCentral uuid:319f17d4-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:319f40d8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:319f6b30-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.126']} DrugCentral uuid:319f96b4-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.253']} DrugCentral uuid:319fbfc2-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:319fe8d0-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.976']} DrugCentral uuid:31a011b6-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.191']} DrugCentral uuid:31a03b6e-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.633']} DrugCentral uuid:31a06472-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.849']} DrugCentral uuid:31a08d76-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.871']} DrugCentral uuid:31a0b6e8-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:31a0dfe2-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:31a108dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:31a131ea-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:979 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebrotidine is antagonist of GPCR (Histamine H2 receptor) DrugCentral uuid:31a157f6-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 echothiophate is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:31a17f42-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.131']} DrugCentral uuid:31a1a85a-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.543']} DrugCentral uuid:31a1d258-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.636']} DrugCentral uuid:31a1fc06-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.336']} DrugCentral uuid:31a22528-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:31a24e22-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.086']} DrugCentral uuid:31a2773a-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:31a2a0c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.052']} DrugCentral uuid:31a2c9c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:31a2f2b4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.648']} DrugCentral uuid:31a31bc2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.617']} DrugCentral uuid:31a346ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.034']} DrugCentral uuid:31a36ff0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.939']} DrugCentral uuid:31a39912-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.362']} DrugCentral uuid:31a3c2e8-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.202']} DrugCentral uuid:31a3ec00-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:31a41522-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.572']} DrugCentral uuid:31a43e44-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.792']} DrugCentral uuid:31a467ac-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.805']} DrugCentral uuid:31a4911e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.197']} DrugCentral uuid:31a4ba22-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.936']} DrugCentral uuid:31a4e33a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.421']} DrugCentral uuid:31a50dd8-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.529']} DrugCentral uuid:31a536fa-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.336']} DrugCentral uuid:31a56008-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.178']} DrugCentral uuid:31a58a42-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:31a5b3dc-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.006']} DrugCentral uuid:31a5dde4-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:31a606e8-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.485']} DrugCentral uuid:31a63000-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.359']} DrugCentral uuid:31a65972-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.463']} DrugCentral uuid:31a682a8-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:31a6a76a-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.294']} DrugCentral uuid:31a6d172-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:31a6fb0c-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.864']} DrugCentral uuid:31a723fc-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:31a74cec-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:31a77672-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.489']} DrugCentral uuid:31a79f6c-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.189']} DrugCentral uuid:31a7c85c-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:31a7f156-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:31a81aa0-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.916']} DrugCentral uuid:31a843ae-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.857']} DrugCentral uuid:31a86c8a-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:31a8958e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:31a8c04a-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:31a8e944-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:31a91248-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:31a93b4c-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:31a96522-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.999']} DrugCentral uuid:31a98e3a-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.431']} DrugCentral uuid:31a9b75c-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.503']} DrugCentral uuid:31a9e0e2-7972-11ec-93d9-0242ac110002 UniProtKB:P49146 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Neuropeptide Y receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.959']} DrugCentral uuid:31aa0aea-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.498']} DrugCentral uuid:31aa340c-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:31aa5d06-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:31aa8740-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:31aab058-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:31aad948-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:31ab024c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:31ab2c04-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:31ab54f4-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:31ab7e0c-7972-11ec-93d9-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:31aba85a-7972-11ec-93d9-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:31abd1ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:31abfb02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:31ac2410-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:31ac4df0-7972-11ec-93d9-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:31ac74ba-7972-11ec-93d9-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:31ac9dbe-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:31acc6d6-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:31acf034-7972-11ec-93d9-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Ceramide glucosyltransferase) DrugCentral uuid:31ad14ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q79MP6 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:31ad3ddc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XAY4 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Unclassified (Beta-lactamase VIM-1; Class B carbapenemase VIM-1; Metallo-beta-lactamase; Metallo-beta-lactamase VIM-1; Metallobeta-lactamase; VIM-1; VIM-1 metallo-beta lactamase; VIM-1 metallo-beta-lactamase; VIM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:31ad66e0-7972-11ec-93d9-0242ac110002 UniProtKB:J3SE37 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:31ad9016-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:31adb91a-7972-11ec-93d9-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:31ade232-7972-11ec-93d9-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:31ae0c26-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edrophonium is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.79']} DrugCentral uuid:31ae37be-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edrophonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:31ae60cc-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:31ae89c6-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:31aeae6a-7972-11ec-93d9-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:31aed7e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:31af00fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:31af2a16-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:31af53ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:31af7d4a-7972-11ec-93d9-0242ac110002 UniProtKB:P11926 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine is inhibitor of Enzyme (Ornithine decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:31afa66c-7972-11ec-93d9-0242ac110002 UniProtKB:P09057 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine targets Enzyme (Ornithine decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:31afcf8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9TZZ6 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine is inhibitor of Enzyme (Ornithine decarboxylase) DrugCentral uuid:31aff536-7972-11ec-93d9-0242ac110002 UniProtKB:O54898 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:31b01e80-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.621']} DrugCentral uuid:31b04b76-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:31b04b76-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:31b07aa6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:31b0a42c-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:31b0cd3a-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.05']} DrugCentral uuid:31b0f652-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:31b11f74-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:31b148f0-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:31b171ea-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:31b19c38-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:31b1ce42-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:31b1ce42-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:31b1ce42-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b24a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:31b328aa-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emedastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:31b351e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:31b37af8-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:31b3a58c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.578']} DrugCentral uuid:31b3cea4-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:31b3f7bc-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:31b420ca-7972-11ec-93d9-0242ac110002 UniProtKB:O75884 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets Enzyme (Putative hydrolase RBBP9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:31b44a32-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emtricitabine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:31b46fd0-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:31b498ac-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:31b4c192-7972-11ec-93d9-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:31b4eafa-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:31b513f4-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:31b53d02-7972-11ec-93d9-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:31b56610-7972-11ec-93d9-0242ac110002 UniProtKB:Q5EGZ1 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:31b5911c-7972-11ec-93d9-0242ac110002 UniProtKB:P09470 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.94']} DrugCentral uuid:31b5ba02-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:31b5de9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:31b60476-7972-11ec-93d9-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:31b629ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:31b64ef4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:31b67398-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 endralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:31b69864-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is positive modulator of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:31b6bda8-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:31b6e292-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:31b70754-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:31b72c2a-7972-11ec-93d9-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:31b7524a-7972-11ec-93d9-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:31b7770c-7972-11ec-93d9-0242ac110002 UniProtKB:Q53I07 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide targets Viral envelope protein (Envelope glycoprotein) DrugCentral uuid:31b79bce-7972-11ec-93d9-0242ac110002 UniProtKB:O40239 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide is inhibitor of Membrane other (Transmembrane glycoprotein gp41) DrugCentral uuid:31b7c086-7972-11ec-93d9-0242ac110002 UniProtKB:Q76270 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide targets Unclassified (GP41) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:31b7e9da-7972-11ec-93d9-0242ac110002 UniProtKB:P43700 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin targets Enzyme (DNA gyrase subunit A) DrugCentral uuid:31b80e88-7972-11ec-93d9-0242ac110002 UniProtKB:P21281 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin targets Enzyme (V-type proton ATPase subunit B, brain isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:31b83b6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5EP76 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:31b83b6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5EP76 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:31b86e8c-7972-11ec-93d9-0242ac110002 UniProtKB:P48371 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:31b86e8c-7972-11ec-93d9-0242ac110002 UniProtKB:P48371 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:31b89e0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.345']} DrugCentral uuid:31b8d35e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:31b8d35e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:31b8d35e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:31b8d35e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:31b921c4-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:31b94b90-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:31b9749e-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:31b99db6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.03']} DrugCentral uuid:31b9c714-7972-11ec-93d9-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:31b9ebb8-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:31ba14c6-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:31ba3dc0-7972-11ec-93d9-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:31ba673c-7972-11ec-93d9-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:31ba9068-7972-11ec-93d9-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:31bab980-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:31bae25c-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:31bb0e4e-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostacyclin receptor) DrugCentral uuid:31bb343c-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:31bb5e62-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:31bb878e-7972-11ec-93d9-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:31bbb10a-7972-11ec-93d9-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:31bbda22-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:31bc031c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:31bc2ca2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:31bc55b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:31bc7f54-7972-11ec-93d9-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.523']} DrugCentral uuid:31bca948-7972-11ec-93d9-0242ac110002 UniProtKB:P17394 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir targets Polyprotein (Protein P) DrugCentral uuid:31bccf40-7972-11ec-93d9-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir is inhibitor of Polyprotein (Protein P) DrugCentral uuid:31bcf40c-7972-11ec-93d9-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:31bd1d06-7972-11ec-93d9-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:31bd4600-7972-11ec-93d9-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:31bd6f5e-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:31bd9862-7972-11ec-93d9-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:31bdc15c-7972-11ec-93d9-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:31bdea60-7972-11ec-93d9-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:31be13c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q00796 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Sorbitol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:31be3cd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q02928 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat is inhibitor of Enzyme (Cytochrome P450 4A11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:31be65ee-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat is inhibitor of Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.678']} DrugCentral uuid:31be8efc-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:31bebb48-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.859']} DrugCentral uuid:31bee46a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:31bf0d8c-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:31bf36e0-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1024 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ephedrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:31bf600c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:31bf84ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:31bfaddc-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:31bfd29e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:31bff7a6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:31c01c86-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:31c04594-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Histamine H2 receptor) DrugCentral uuid:31c06a4c-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:31c09468-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:31c0bd62-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:31c0e76a-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:31c110d2-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.401']} DrugCentral uuid:31c13b20-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:31c16456-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.26']} DrugCentral uuid:31c18d82-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:31c1b820-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:31c1e138-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.434']} DrugCentral uuid:31c20a82-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:31c233b8-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.401']} DrugCentral uuid:31c25eec-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.449']} DrugCentral uuid:31c2880e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:31c2b144-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:31c2da52-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.484']} DrugCentral uuid:31c303d8-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:31c32cfa-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:31c35612-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:31c37fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:31c3a8d8-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:31c3d204-7972-11ec-93d9-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:31c3fb26-7972-11ec-93d9-0242ac110002 UniProtKB:P10608 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:31c425a6-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:31c45670-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:31c45670-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:31c45670-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:31c49f54-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:31c49f54-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:31c49f54-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:31c4e23e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8I2J3 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Enzyme (M18 aspartyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:31c50b6a-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.878']} DrugCentral uuid:31c5348c-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.286']} DrugCentral uuid:31c55dea-7972-11ec-93d9-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:31c586f8-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:31c5b01a-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:31c5d946-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:31c604fc-7972-11ec-93d9-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:31c62edc-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:31c65808-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear other (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:31c68134-7972-11ec-93d9-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:31c6aa9c-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:31c6d3a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol targets GPCR (P2Y purinoceptor 12) DrugCentral uuid:31c6f984-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:31c722b0-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:31c74c4a-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:31c77558-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:31c79e7a-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:31c7ccce-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:31c7ccce-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:31c809a0-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:31c809a0-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:31c809a0-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:31c85054-7972-11ec-93d9-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:1040 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptifibatide is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:31c85054-7972-11ec-93d9-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:1040 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptifibatide is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:31c885c4-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:31c8aee6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:31c8d7ea-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:31c9017a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.333']} DrugCentral uuid:31c92a9c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:31c953b4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.58']} DrugCentral uuid:31c97cd6-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:31c9a81e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:31c9d17c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:31c9fab2-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.714']} DrugCentral uuid:31ca23c0-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:31ca4d32-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.367']} DrugCentral uuid:31ca765e-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:31ca9f58-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.889']} DrugCentral uuid:31cac884-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:31caf200-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:31cb1b36-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:31cb4462-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.621']} DrugCentral uuid:31cb6e9c-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.722']} DrugCentral uuid:31cb97be-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:31cbc0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:31cbea0c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.099']} DrugCentral uuid:31cc1388-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:31cc3d7c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.354']} DrugCentral uuid:31cc66a8-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:31cc9100-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:31ccba9a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:31cce3b2-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:31cd0cde-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:31cd31b4-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.754']} DrugCentral uuid:31cd5cac-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.836']} DrugCentral uuid:31cd85b0-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:31cdaebe-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.064']} DrugCentral uuid:31cdd7c2-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:31ce015c-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:31ce2a92-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:31ce53b4-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.742']} DrugCentral uuid:31ce7d3a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.487']} DrugCentral uuid:31cea666-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:31cecf92-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:31cef940-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:31cf237a-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:31cf4c88-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:31cf7596-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.514']} DrugCentral uuid:31cf9ea4-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.342']} DrugCentral uuid:31cfc834-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.041']} DrugCentral uuid:31cff156-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:31d01a5a-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.11']} DrugCentral uuid:31d0437c-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:31d06e1a-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:31d09746-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:31d0c072-7972-11ec-93d9-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:31d0e98a-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:31d113a6-7972-11ec-93d9-0242ac110002 UniProtKB:O08786 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Cholecystokinin A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:31d13cbe-7972-11ec-93d9-0242ac110002 UniProtKB:O32393 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Unclassified (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:31d165cc-7972-11ec-93d9-0242ac110002 UniProtKB:P35364 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:31d18f48-7972-11ec-93d9-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:31d1b86a-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:31d1e178-7972-11ec-93d9-0242ac110002 UniProtKB:O00206 biolink:molecularly_interacts_with DrugCentral:1044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eritoran targets Membrane receptor (Toll-like receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:31d20a7c-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:31d2340c-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:31d25d10-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:31d286b4-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:31d2b0e4-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:31d2dc90-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:31d3059e-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:31d32ec0-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:31d357ec-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:31d38172-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:31d3aa80-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:31d3d398-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:31d3fd14-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:31d42636-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:31d44f44-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:31d47938-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:31d4a458-7972-11ec-93d9-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:31d4cdf2-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:31d4f6f6-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:31d52018-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:31d5499e-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:31d572b6-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:31d59c64-7972-11ec-93d9-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:31d5c572-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:31d5eef8-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:31d61824-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:31d6415a-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:31d66bb2-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:31d6951a-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:31d6be28-7972-11ec-93d9-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:31d6e754-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:31d710b2-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:31d739c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:31d762ba-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:31d78be6-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:31d7b562-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:31d7de84-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:31d80788-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:31d830aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:31d85bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:31d885dc-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:31d8b020-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:31d8d988-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:31d902aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:31d92bc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:31d954da-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:31d97e60-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:31d9a76e-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:31d9d07c-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:31d9f994-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:31da23e2-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:31da4ce6-7972-11ec-93d9-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:31da75f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:31da9f0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:31dac892-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:31daf1a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:31db1acc-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:31db43bc-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:31db6d42-7972-11ec-93d9-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:31db9646-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:31dbbf68-7972-11ec-93d9-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:31dbe98e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:31dc12b0-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:31dc3bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:31dc64ea-7972-11ec-93d9-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:31dc8fd8-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:31dcb8fa-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:31dce212-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:31dd0b3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:31dd34e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:31dd5dfa-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:31dd8708-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:31ddb020-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:31ddda96-7972-11ec-93d9-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:31de039a-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:31de2cbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:31de55c0-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:31de7f3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:31dea840-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:31ded284-7972-11ec-93d9-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:31defc00-7972-11ec-93d9-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:31df250e-7972-11ec-93d9-0242ac110002 UniProtKB:P31152 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:31df4e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:31df7734-7972-11ec-93d9-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:31dfa146-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:31dfca68-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:31dff376-7972-11ec-93d9-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:31e01c98-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:31e045f6-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:31e06f0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:31e09934-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:31e0c256-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:31e0ec18-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:31e11526-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:31e13e34-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:31e16864-7972-11ec-93d9-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:31e191ae-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:31e1bac6-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:31e1e3d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:31e20d3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:31e23654-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:31e25f80-7972-11ec-93d9-0242ac110002 UniProtKB:O94956 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib is inhibitor of Transporter (Solute carrier organic anion transporter family member 2B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:31e288b6-7972-11ec-93d9-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:31e2b278-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:31e2d73a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:31e2fc10-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:31e32172-7972-11ec-93d9-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:31e3471a-7972-11ec-93d9-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:31e36bdc-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (D-alanyl-D-alanine carboxypeptidase DacB) DrugCentral uuid:31e390a8-7972-11ec-93d9-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:31e3b588-7972-11ec-93d9-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (Penicillin-binding protein 1B) DrugCentral uuid:31e3dab8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:31e403a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:31e42c98-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:31e4559c-7972-11ec-93d9-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:31e47f54-7972-11ec-93d9-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:31e4a948-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:31e4d378-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:31e4fc9a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:31e52742-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.186']} DrugCentral uuid:31e5505a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:31e57968-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.412']} DrugCentral uuid:31e5a26c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.706']} DrugCentral uuid:31e5cbde-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:31e5f4ec-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:31e61e0e-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:31e64794-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:31e670c0-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:31e699e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:31e6c2f0-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:31e6f0f4-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esomeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:31e6f0f4-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esomeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:31e727fe-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:31e727fe-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:31e727fe-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:31e7694e-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:31e7694e-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:31e7694e-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:31e7ab20-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:31e7ab20-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:31e7ab20-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:31e7ec98-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:31e7ec98-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:31e7ec98-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:31e82816-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.243']} DrugCentral uuid:31e8511a-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.538']} DrugCentral uuid:31e879e2-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.725']} DrugCentral uuid:31e8a2e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.926']} DrugCentral uuid:31e8cdd4-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:31e8f930-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:31e9223e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol is activator of Ion channel (Calcium-activated potassium channel subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:31e94b1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:31e97464-7972-11ec-93d9-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:31e99d36-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:31e9c7f2-7972-11ec-93d9-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:31e9f178-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.83']} DrugCentral uuid:31ea1a86-7972-11ec-93d9-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:31ea4394-7972-11ec-93d9-0242ac110002 UniProtKB:O95718 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Steroid hormone receptor ERR2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:31ea6cac-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:31ea970e-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.947']} DrugCentral uuid:31eac062-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.372']} DrugCentral uuid:31eae984-7972-11ec-93d9-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:31eb129c-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:31eb3c04-7972-11ec-93d9-0242ac110002 UniProtKB:O08537 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:31eb6526-7972-11ec-93d9-0242ac110002 UniProtKB:P19785 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:31eb8e2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:31ebbaf8-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:31ebbaf8-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:31ebf194-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:31ec1ab6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.767']} DrugCentral uuid:31ec43ec-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.133']} DrugCentral uuid:31ec6e80-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.637']} DrugCentral uuid:31ec97a2-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.446']} DrugCentral uuid:31ecc0ba-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:31ece9e6-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:31ed136c-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.94']} DrugCentral uuid:31ed3c7a-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.638']} DrugCentral uuid:31ed6592-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.156']} DrugCentral uuid:31ed8ebe-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.902']} DrugCentral uuid:31edb88a-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol cypionate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:31eddd42-7972-11ec-93d9-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol mustard targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:31ee066e-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol valerate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:31ee2b4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate is modulator of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:31ee5308-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:31ee7ebe-7972-11ec-93d9-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:31eea7d6-7972-11ec-93d9-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:31eed0ee-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:31eefa56-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:31ef2378-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:31ef4d26-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:31ef76b6-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:31efa0e6-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.63']} DrugCentral uuid:31efc9f4-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:31eff41a-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:31f01ee0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:31f047da-7972-11ec-93d9-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:31f07124-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:31f09a46-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:31f0c3d6-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:31f0f4aa-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:31f0f4aa-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:31f0f4aa-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:31f13622-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:31f13622-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:31f13622-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:31f17844-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:31f17844-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:31f17844-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:31f1b9a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:31f1b9a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:31f1b9a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:31f1fbd4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:31f1fbd4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:31f1fbd4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:31f23d42-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:31f23d42-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:31f23d42-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:31f2771c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid is inhibitor of Transporter (Solute carrier family 12 member 1) DrugCentral uuid:31f29c38-7972-11ec-93d9-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Glutathione S-transferase P) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:31f2c550-7972-11ec-93d9-0242ac110002 UniProtKB:P08263 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Glutathione S-transferase A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:31f2ef3a-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.939']} DrugCentral uuid:31f3187a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:31f34188-7972-11ec-93d9-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:31f36a96-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:31f39390-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:31f3bdd4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:31f3e73c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:31f41036-7972-11ec-93d9-0242ac110002 UniProtKB:P9WNL8 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase A) DrugCentral uuid:31f43610-7972-11ec-93d9-0242ac110002 UniProtKB:P9WNL6 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase B) DrugCentral uuid:31f45b68-7972-11ec-93d9-0242ac110002 UniProtKB:P9WNL5 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase C) DrugCentral uuid:31f4800c-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:31f4a91a-7972-11ec-93d9-0242ac110002 UniProtKB:P9WNL9 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol is inhibitor of Enzyme (Probable arabinosyltransferase A) DrugCentral uuid:31f4cddc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:31f4f2da-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:31f51792-7972-11ec-93d9-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glycine receptor subunit alpha-2) DrugCentral uuid:31f543d4-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:31f543d4-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:31f543d4-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:31f585ce-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:31f585ce-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:31f585ce-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:31f5c066-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:31f5e988-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:31f61264-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.964']} DrugCentral uuid:31f63c26-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:31f66534-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:31f68e38-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.022']} DrugCentral uuid:31f6b732-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:31f6e176-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:31f70a70-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.353']} DrugCentral uuid:31f73388-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:31f75caa-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.985']} DrugCentral uuid:31f78694-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.83']} DrugCentral uuid:31f7af8e-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:31f7d874-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:31f8020e-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.81']} DrugCentral uuid:31f82b12-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:31f8540c-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.246']} DrugCentral uuid:31f87d10-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.857']} DrugCentral uuid:31f8a68c-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:31f8cf7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:31f8f86c-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:31f92148-7972-11ec-93d9-0242ac110002 UniProtKB:P9WIE4 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide targets Enzyme (Catalase-peroxidase) DrugCentral uuid:31f946b4-7972-11ec-93d9-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) DrugCentral uuid:31f96b62-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:31f9959c-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:31f9bec8-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.78']} DrugCentral uuid:31f9e894-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:31fa11a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.111']} DrugCentral uuid:31fa3ac4-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:31fa63e6-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:31fa8902-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:31faadce-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.61']} DrugCentral uuid:31fad6e6-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:31fb00e4-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:31fb2e20-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:31fb57c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:31fb80d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:31fbaaa8-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:31fbd3b6-7972-11ec-93d9-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethosuximide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc1aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:31fc9e18-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:31fcc758-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:31fcf142-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:31fd1a82-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:31fd43b8-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:31fd6cee-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:31fd96ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:31fdc00e-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:31fde91c-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:31fe1248-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:31fe3bd8-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:31fe650e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:31fe8f16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:31febaae-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:31fee420-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:31ff0d38-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:31ff365a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:31ff6008-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:31ff8920-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:31ffb242-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:31ffdb5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:320004d6-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:32002dee-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:32005706-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:320080a0-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3200aa94-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3200d3a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3200fcb0-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:32012a6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32012a6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32015f98-7972-11ec-93d9-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:32018892-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:3201b1aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:3201db12-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:32020420-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:1091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl biscoumacetate targets Enzyme (Vitamin K epoxide reductase complex subunit 1) DrugCentral uuid:320228c4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:320251e6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:32027cd4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.983']} DrugCentral uuid:3202a6d2-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:3202cfcc-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:3202f47a-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:32031e32-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.889']} DrugCentral uuid:3203472c-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:3203703a-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:320399ac-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:3203be64-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:3203e31c-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.368']} DrugCentral uuid:32040c0c-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:3204360a-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:32045f0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:320485d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:3204aac2-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:3204d02e-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:3204f91e-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:32052218-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:32054b26-7972-11ec-93d9-0242ac110002 UniProtKB:B1LRJ1 biolink:molecularly_interacts_with DrugCentral:1098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidronic acid targets Unclassified (Type IV secretion-like conjugative transfer relaxase protein TraI) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32057498-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilamfetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:32059db0-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilefrine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:3205ca92-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3205ca92-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3205ca92-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3206151a-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:3206151a-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:3206151a-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:3206566a-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:3206566a-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:3206566a-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:320698fa-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:320698fa-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:320698fa-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:3206d392-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etodolac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3206fc82-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etodolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.577']} DrugCentral uuid:32072586-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:1107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etofylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:32074f16-7972-11ec-93d9-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:32077824-7972-11ec-93d9-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3207a11e-7972-11ec-93d9-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:3207ca36-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3207fe5c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:3207fe5c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:3207fe5c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:32084bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:32084bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:32084bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:32088d54-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:3208b220-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:3208d6d8-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:3208ffc8-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:32092a7a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.051']} DrugCentral uuid:3209537e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.071']} DrugCentral uuid:32097ca0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:3209a5a4-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.282']} DrugCentral uuid:3209d326-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.21']} DrugCentral uuid:3209ff72-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:320a2722-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:320a5120-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:320a75a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:320a9a4a-7972-11ec-93d9-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:320abeee-7972-11ec-93d9-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Canalicular multispecific organic anion transporter 2) DrugCentral uuid:320ae3a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:320b0d18-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.497']} DrugCentral uuid:320b3626-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:320b5f2a-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:320b895a-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.102']} DrugCentral uuid:320bb268-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:320bdb76-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:320c0484-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:320c2eaa-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:320c57ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:320c80bc-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:320ca9c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:320cd33c-7972-11ec-93d9-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Canalicular multispecific organic anion transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:320cfc2c-7972-11ec-93d9-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:320d253a-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:320d49e8-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:320d74b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:320d9dc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:320dc6de-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:1116 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etretinate is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) DrugCentral uuid:320decae-7972-11ec-93d9-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:1116 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etretinate is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) DrugCentral uuid:320e1206-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.63']} DrugCentral uuid:320e3aec-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:320e63c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:320e8c9a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:320eb1c0-7972-11ec-93d9-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:320edaba-7972-11ec-93d9-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:320f03b4-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exemestane targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:320f2998-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exemestane is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.692']} DrugCentral uuid:320f551c-7972-11ec-93d9-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:1123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exenatide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.18']} DrugCentral uuid:320f7e20-7972-11ec-93d9-0242ac110002 UniProtKB:P32301 biolink:molecularly_interacts_with DrugCentral:1123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exenatide targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:320fa742-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHC9 biolink:molecularly_interacts_with DrugCentral:1125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ezetimibe is antagonist of Membrane other (Niemann-Pick C1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:320fd0f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6T3U3 biolink:molecularly_interacts_with DrugCentral:1125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ezetimibe targets Unclassified (Niemann-Pick C1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:320ffa12-7972-11ec-93d9-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:32102302-7972-11ec-93d9-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:32104bfc-7972-11ec-93d9-0242ac110002 UniProtKB:P15539 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3210758c-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:32109e9a-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:3210c33e-7972-11ec-93d9-0242ac110002 UniProtKB:P09252 biolink:molecularly_interacts_with DrugCentral:1128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famciclovir targets Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:3210e7ec-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.93']} DrugCentral uuid:32111316-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:32113d32-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:32116654-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:32118f80-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3211b9e2-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:3211e2fa-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:32120d02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3212361a-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32125fa0-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:321288c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3212b1d0-7972-11ec-93d9-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3212db92-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:321304be-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:32132dae-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3213569e-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:32138024-7972-11ec-93d9-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.304']} DrugCentral uuid:3213a914-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:3213d1fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:1130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famprofazone targets Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3213fb08-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:32142470-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.44']} DrugCentral uuid:32144d7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:32147678-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:32149f5e-7972-11ec-93d9-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3214cbaa-7972-11ec-93d9-0242ac110002 UniProtKB:P13500 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Cytokine (C-C motif chemokine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3214f670-7972-11ec-93d9-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:321520aa-7972-11ec-93d9-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:32154a3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q62868 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3215733e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:32159c60-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3215c55a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3215eea4-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:321618ac-7972-11ec-93d9-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:321641b0-7972-11ec-93d9-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:32166abe-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbamate is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 2A) DrugCentral uuid:32169188-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbamate is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.284']} DrugCentral uuid:3216bb0e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbinac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:3216dfee-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbinac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.049']} DrugCentral uuid:321708fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:3217332c-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:32175c6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:32178138-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:3217a604-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.339']} DrugCentral uuid:3217d142-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.168']} DrugCentral uuid:3217fa5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:32182372-7972-11ec-93d9-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is activator of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:32185522-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:32185522-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:32185522-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:32189b0e-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3218c426-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3218ed34-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:321912b4-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:3219376c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:32196098-7972-11ec-93d9-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:32198988-7972-11ec-93d9-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3219b2e6-7972-11ec-93d9-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3219dbea-7972-11ec-93d9-0242ac110002 UniProtKB:P35384 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline is positive allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:321a05ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.004']} DrugCentral uuid:321a3018-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:321a5976-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.428']} DrugCentral uuid:321a8284-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:321aab88-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.172']} DrugCentral uuid:321ad540-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.845']} DrugCentral uuid:321affb6-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:321b28ba-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:321b51d2-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.042']} DrugCentral uuid:321b7b4e-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:321ba466-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:321bcd6a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.717']} DrugCentral uuid:321bf66e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.016']} DrugCentral uuid:321c2026-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.726']} DrugCentral uuid:321c4934-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.489']} DrugCentral uuid:321c722e-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:321c9be6-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:321cc4ea-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.195']} DrugCentral uuid:321cedf8-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.735']} DrugCentral uuid:321d16fc-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:321d4078-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:321d6954-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.673']} DrugCentral uuid:321d9262-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:321dbb8e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:321de5aa-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.331']} DrugCentral uuid:321e1048-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.032']} DrugCentral uuid:321e396a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.164']} DrugCentral uuid:321e6264-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:321e8bfe-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.808']} DrugCentral uuid:321eb52a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:321ede42-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:321f073c-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:321f30e0-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:321f59da-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:321f82e8-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:321faca0-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:321fd5ae-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:321ffee4-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:322027f2-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3220515a-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:32207a7c-7972-11ec-93d9-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3220ab50-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3220ab50-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3220ab50-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3220ee76-7972-11ec-93d9-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:322117a2-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:32214092-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:322169be-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:322194a2-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:3221c170-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:3221c170-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:3221f794-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N695 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Transporter (Sodium-coupled monocarboxylate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:322220fc-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:32224a0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3222730e-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.001']} DrugCentral uuid:32229c12-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:3222c5c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3222eece-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:322317e6-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3223411c-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:32236c3c-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:32239536-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:3223be3a-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:3223e752-7972-11ec-93d9-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:32241132-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:32243a54-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:32246376-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:32248d24-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3224c190-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:3224c190-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:3224c190-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:3224c190-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:3225126c-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3225126c-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:32254b60-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:322574d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:32259ec6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:3225c842-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentiazac targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:3225f150-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:32261a4a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.699']} DrugCentral uuid:32264376-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:32266e78-7972-11ec-93d9-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.699']} DrugCentral uuid:322697ae-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:3226c0da-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3226e9f2-7972-11ec-93d9-0242ac110002 UniProtKB:P14060 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:322715da-7972-11ec-93d9-0242ac110002 UniProtKB:P24008 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:32273f56-7972-11ec-93d9-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:32276c42-7972-11ec-93d9-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:32276c42-7972-11ec-93d9-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:3227a1ee-7972-11ec-93d9-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:3227cafc-7972-11ec-93d9-0242ac110002 UniProtKB:P18405 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:3227f414-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.704']} DrugCentral uuid:322828c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:322828c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:322828c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:322828c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:322871b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 7) DrugCentral uuid:322871b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 7) DrugCentral uuid:3228a4ea-7972-11ec-93d9-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 8) DrugCentral uuid:3228a4ea-7972-11ec-93d9-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 8) DrugCentral uuid:3228d596-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3228feae-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:322927b2-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.745']} DrugCentral uuid:322951c4-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:32297b4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.77']} DrugCentral uuid:3229a458-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3229cd84-7972-11ec-93d9-0242ac110002 UniProtKB:Q63881 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3229f69c-7972-11ec-93d9-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:322a20d6-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fleroxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:322a4a02-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floctafenine is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:322a7324-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floctafenine is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.268']} DrugCentral uuid:322a9c46-7972-11ec-93d9-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:1180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flopropione is inhibitor of Enzyme (Catechol O-methyltransferase) DrugCentral uuid:322ac20c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:322ae6ba-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:322b0fbe-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:322b38ea-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxuridine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:322b5e2e-7972-11ec-93d9-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:1184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxuridine targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:322b873c-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:322bb05e-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:322bda98-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:322c043c-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:322c2d4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:322c5680-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:322c80ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:322caad6-7972-11ec-93d9-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:322cd3ee-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:322cfd1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q7Z1V1 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Sterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:322d2678-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:322d5080-7972-11ec-93d9-0242ac110002 UniProtKB:P0CS13 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:322d7556-7972-11ec-93d9-0242ac110002 UniProtKB:P12461 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:322d9a2c-7972-11ec-93d9-0242ac110002 UniProtKB:P02829 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine targets Cytosolic other (ATP-dependent molecular chaperone HSP82) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:322dc3d0-7972-11ec-93d9-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:322ded06-7972-11ec-93d9-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:322e160a-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:322e3f22-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:322e6b3c-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:322e9620-7972-11ec-93d9-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:322ebf56-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:322ee8b4-7972-11ec-93d9-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:322f0d6c-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:322f3666-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate targets Cytosolic other (Annexin A1) DrugCentral uuid:322f5b46-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:322f8468-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:322faea2-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:322fd7a6-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:323000c8-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:32302b52-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:323054d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:32307dd2-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3230a6cc-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3230d03e-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3230f988-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:323122a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6UVM3 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is activator of Ion channel (Potassium channel subfamily T member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:32314c9e-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:32317638-7972-11ec-93d9-0242ac110002 UniProtKB:O94759 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:3231a068-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3231c976-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:3231f298-7972-11ec-93d9-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:32321cbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZQ8 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:323245d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q7TN37 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:32326f0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:32329888-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3232c182-7972-11ec-93d9-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:3232ea86-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:323313bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is agonist of GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.863']} DrugCentral uuid:32333d60-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:3233666e-7972-11ec-93d9-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32338fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:3233b8d0-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:3233e31e-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:32340c7c-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32343d5a-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:32343d5a-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:32343d5a-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:323486c0-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:323486c0-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:323486c0-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:3234d102-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:3234d102-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:3234d102-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:32351aae-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:32351aae-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:32351aae-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3235957e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:32368db2-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:32368db2-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:32368db2-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:32368db2-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:32368db2-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:32368db2-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:3236fcac-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3236fcac-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3236fcac-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:323745ae-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:323745ae-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:323745ae-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:32379112-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:32379112-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:32379112-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3237da6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:3237da6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:3237da6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32385570-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32393652-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumetasone pivalate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:32395d44-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.621']} DrugCentral uuid:32398684-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3239af92-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.713']} DrugCentral uuid:3239d8b4-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:323a0244-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.662']} DrugCentral uuid:323a2b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:323a5488-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.304']} DrugCentral uuid:323a7db4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:323aa762-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:323ad07a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:323af99c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:323b237c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:323b4cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.455']} DrugCentral uuid:323b75d4-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:323b9f0a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:323bc962-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:323bf284-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.151']} DrugCentral uuid:323c1b9c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.504']} DrugCentral uuid:323c44be-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.103']} DrugCentral uuid:323c6e8a-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:323c97b6-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:323cc0e2-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:323cea68-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.333']} DrugCentral uuid:323d1434-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.532']} DrugCentral uuid:323d3d56-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.357']} DrugCentral uuid:323d6678-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:323d8fea-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:323db902-7972-11ec-93d9-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:323de210-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:323e0b32-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:323e34f4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:323e5df8-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:323e86fc-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:323eb014-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:323ee372-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:323ee372-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:323ee372-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:323f24d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y256 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:323f4dbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:323f7706-7972-11ec-93d9-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:323fa10e-7972-11ec-93d9-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:323fca4e-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:323ff366-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:32401d5a-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunisolide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:32404654-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunisolide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:32406f8a-7972-11ec-93d9-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:324098c0-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:3240c48a-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3240edd4-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:32411e94-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:32411e94-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:32411e94-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:324167c8-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:324167c8-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:324167c8-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:3241b0ca-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:3241b0ca-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:3241b0ca-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:3241fa8a-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:3241fa8a-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:3241fa8a-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:32424382-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:32424382-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:32424382-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:32428f4a-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:32428f4a-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:32428f4a-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324309fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3243f1fa-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:3243f1fa-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:3243f1fa-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:32443b06-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:32443b06-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:32443b06-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:32448732-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:32448732-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:32448732-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3244d02a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3244d02a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3244d02a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:324519a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:324519a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:324519a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:32455b08-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1204 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinolone acetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.848']} DrugCentral uuid:324584de-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1204 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinolone acetonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.475']} DrugCentral uuid:3245ae14-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1205 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.622']} DrugCentral uuid:3245d736-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1205 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.538']} DrugCentral uuid:3246004e-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.042']} DrugCentral uuid:32462a06-7972-11ec-93d9-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:3246530a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:32467c2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:3246a562-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.801']} DrugCentral uuid:3246cede-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.067']} DrugCentral uuid:3246f94a-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:3247224e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:32474b7a-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:32477546-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:32479f26-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:3247c848-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.091']} DrugCentral uuid:3247f25a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:32481b86-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:324844b2-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:32486dca-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3248973c-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3248c054-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:3248e980-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:324912ac-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:32493c64-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.959']} DrugCentral uuid:3249657c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.047']} DrugCentral uuid:32498e8a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:3249b7ac-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3249e27c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.538']} DrugCentral uuid:324a0b9e-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:324a34ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.444']} DrugCentral uuid:324a5dce-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:324a872c-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:324ab0c6-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:324ad9c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:324b0396-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:324b2cb8-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:324b55d0-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:324b7ee8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:324baabc-7972-11ec-93d9-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:324bd6ae-7972-11ec-93d9-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:324bffd0-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:324c2906-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:324c5278-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:324c8702-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:324c8702-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:324c8702-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:324c8702-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:324cde00-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:324cde00-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:324cde00-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:324d26f8-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:324d26f8-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:324d26f8-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:324d6852-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:324d93d6-7972-11ec-93d9-0242ac110002 UniProtKB:P25122 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:324dbcee-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:324de610-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxymesterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:324e0fd2-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:324e3912-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:324e6234-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.65']} DrugCentral uuid:324e8b2e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:324eb4dc-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.058']} DrugCentral uuid:324eddfe-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:324f03b0-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:324f2cc8-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:324f5720-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.066']} DrugCentral uuid:324f8042-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:324fa978-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:324fd27c-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:324ffbe4-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:325024fc-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:32505d50-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32505d50-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32505d50-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32505d50-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32505d50-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3250b70a-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.075']} DrugCentral uuid:3250e02c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.649']} DrugCentral uuid:3251094e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.269']} DrugCentral uuid:32513586-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.503']} DrugCentral uuid:32515e9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.067']} DrugCentral uuid:325187c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3251b0ec-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:3251da72-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.711']} DrugCentral uuid:325204b6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.838']} DrugCentral uuid:32522dce-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.044']} DrugCentral uuid:325257ae-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:325280da-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:3252aaf6-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.464']} DrugCentral uuid:3252d40e-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:3252ff38-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.191']} DrugCentral uuid:32532a6c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.087']} DrugCentral uuid:3253537a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:32537c9c-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.887']} DrugCentral uuid:3253a618-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.793']} DrugCentral uuid:3253cf3a-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:3253f852-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:32542160-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.575']} DrugCentral uuid:32544b2c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.999']} DrugCentral uuid:3254743a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.315']} DrugCentral uuid:32549d48-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.447']} DrugCentral uuid:3254c796-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.655']} DrugCentral uuid:3254f0c2-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:325519ee-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:325542fc-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.539']} DrugCentral uuid:32556c78-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.788']} DrugCentral uuid:325595ae-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:3255beb2-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.535']} DrugCentral uuid:3255e7e8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.019']} DrugCentral uuid:325611b4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:32563ae0-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.005']} DrugCentral uuid:3256642a-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.072']} DrugCentral uuid:32568d56-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:3256b826-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:3256e148-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.397']} DrugCentral uuid:32570a56-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:325733c8-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.097']} DrugCentral uuid:32575cd6-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.708']} DrugCentral uuid:325785ee-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.125']} DrugCentral uuid:3257af10-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3257d8be-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.67']} DrugCentral uuid:325803a2-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:32582cce-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.061']} DrugCentral uuid:325855fa-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.049']} DrugCentral uuid:3258808e-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:3258a9a6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:3258d2be-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:3258fbea-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3259255c-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:32594e92-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:32597f48-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:32597f48-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:32597f48-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3259db8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3259db8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3259db8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3259db8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3259db8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3259db8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3259db8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3259db8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:325a5c92-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine decanoate is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:325a8154-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:325aaa9e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.268']} DrugCentral uuid:325ad3d4-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.503']} DrugCentral uuid:325afd64-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.225']} DrugCentral uuid:325b2672-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.837']} DrugCentral uuid:325b4f80-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:325b794c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.048']} DrugCentral uuid:325ba264-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:325bcb86-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:325bf4a8-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:325c1e9c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.087']} DrugCentral uuid:325c47b4-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.611']} DrugCentral uuid:325c70ea-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.887']} DrugCentral uuid:325c9a16-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:325cc39c-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:325cedf4-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.961']} DrugCentral uuid:325d1716-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.145']} DrugCentral uuid:325d4042-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.841']} DrugCentral uuid:325d6a04-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.274']} DrugCentral uuid:325d931c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.447']} DrugCentral uuid:325dbc48-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:325de650-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:325e1350-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.539']} DrugCentral uuid:325e3cfe-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:325e6634-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:325e8fa6-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:325eb8be-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:325ee1ea-7972-11ec-93d9-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:325f0af8-7972-11ec-93d9-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine targets Ion channel (Potassium voltage-gated channel subfamily KQT member 3) DrugCentral uuid:325f3078-7972-11ec-93d9-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:325f5990-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1216 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluprednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:325f7f06-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludroxycortide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.695']} DrugCentral uuid:325fa83c-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludroxycortide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:325fd398-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.222']} DrugCentral uuid:32600480-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:32600480-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:32600480-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:326045d0-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:32606f4c-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:32609878-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:3260c19a-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:3260eaa8-7972-11ec-93d9-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:32611474-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:32613d78-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:32616690-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:32618fb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3261bc94-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:3261e5c0-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:32620ece-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.436']} DrugCentral uuid:32623840-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.244']} DrugCentral uuid:32626162-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32628a84-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3262b4f0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3262deb2-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:326307d4-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:3263310a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:32635a2c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:32638524-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3263ae46-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.951']} DrugCentral uuid:3263d77c-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3264008a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.208']} DrugCentral uuid:326429fc-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.056']} DrugCentral uuid:3264531e-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32647c18-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3264a5f8-7972-11ec-93d9-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3264cf10-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:3264f850-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.082']} DrugCentral uuid:326521a4-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:32654b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:326574a6-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.049']} DrugCentral uuid:32659daa-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:3265c7ee-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.74']} DrugCentral uuid:3265f17e-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:32661b0e-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.77']} DrugCentral uuid:32664408-7972-11ec-93d9-0242ac110002 UniProtKB:P47712 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate targets Enzyme (Cytosolic phospholipase A2) DrugCentral uuid:326668f2-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.12']} DrugCentral uuid:326692be-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutrimazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3266bbcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutrimazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:3266e4e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:3267099c-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:32673386-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.96']} DrugCentral uuid:32675cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:326785ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:3267af64-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:3267d8ae-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:326801a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:32682af2-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:326854a0-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.951']} DrugCentral uuid:32687dc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:3268a7de-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3268d100-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:3268fb44-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3269247a-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 folic acid targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:32694d9c-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 folic acid targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:326976aa-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucovorin targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.071']} DrugCentral uuid:3269a04e-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:1232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucovorin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:3269d226-7972-11ec-93d9-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:3269d226-7972-11ec-93d9-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:3269d226-7972-11ec-93d9-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:326a0fd4-7972-11ec-93d9-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:326a0fd4-7972-11ec-93d9-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:326a45e4-7972-11ec-93d9-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:1236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fondaparinux is activator of Secreted (Antithrombin-III) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:326a6f10-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formestane targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:326a983c-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:326ac2da-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:326aec4c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:326b156e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:326b3e90-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:326b6802-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:326b9106-7972-11ec-93d9-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:326bba96-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosamprenavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:326bdf62-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosamprenavir is inhibitor of Enzyme (Pol polyprotein) DrugCentral uuid:326c04ec-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet is inhibitor of Enzyme (DNA polymerase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:326c2e0e-7972-11ec-93d9-0242ac110002 UniProtKB:P08546 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (DNA polymerase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:326c5708-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:326c8020-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:326cabe0-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfluconazole targets Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:326cd098-7972-11ec-93d9-0242ac110002 UniProtKB:Q836E5 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1) DrugCentral uuid:326cf55a-7972-11ec-93d9-0242ac110002 UniProtKB:Q831A8 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2) DrugCentral uuid:326d1a4e-7972-11ec-93d9-0242ac110002 UniProtKB:P0A749 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin is inhibitor of Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:326d43d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HVW7 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:326d6cf6-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosinopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:326d9604-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosinopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:326dc034-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosphenytoin is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:326de5b4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:326e0ef4-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:326e383e-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:326e6336-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fructose targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:326e8cd0-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ftivazide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:326eb5de-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:326eded8-7972-11ec-93d9-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:326f0840-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:326f313a-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.68']} DrugCentral uuid:326f5a5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant is antagonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:326f836a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:326fad0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:326fd612-7972-11ec-93d9-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:326fff16-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:3270282e-7972-11ec-93d9-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:327053b2-7972-11ec-93d9-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:32707ca2-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furaltadone targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:3270a5c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3270ceaa-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:3270f45c-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:32711d74-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:327146aa-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:32717058-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3271997a-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:3271c378-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3271ec90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:327216e8-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:32724208-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:32726b2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:32729474-7972-11ec-93d9-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3272bddc-7972-11ec-93d9-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3272e6fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:32731016-7972-11ec-93d9-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:32733910-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:327362dc-7972-11ec-93d9-0242ac110002 UniProtKB:P96618 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Holo-[acyl-carrieir-protein] synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:32738bfe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3273b502-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fusidic acid targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:3273de10-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fusidic acid targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:32740976-7972-11ec-93d9-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:32743284-7972-11ec-93d9-0242ac110002 UniProtKB:P23978 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:32745cbe-7972-11ec-93d9-0242ac110002 UniProtKB:P31648 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:32748626-7972-11ec-93d9-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3274af3e-7972-11ec-93d9-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3274d86a-7972-11ec-93d9-0242ac110002 UniProtKB:P24046 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:32750182-7972-11ec-93d9-0242ac110002 UniProtKB:P48066 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:32752b62-7972-11ec-93d9-0242ac110002 UniProtKB:P48065 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent betaine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:32755470-7972-11ec-93d9-0242ac110002 UniProtKB:P31650 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:32757d88-7972-11ec-93d9-0242ac110002 UniProtKB:P31646 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3275a790-7972-11ec-93d9-0242ac110002 UniProtKB:P31649 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:3275d382-7972-11ec-93d9-0242ac110002 UniProtKB:P23574 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3275fd94-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid is agonist of GPCR (Gamma-aminobutyric acid type B receptor subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:327626ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSD5 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:32764fce-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:327674e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:32769998-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Adenosine receptor A1) DrugCentral uuid:3276be46-7972-11ec-93d9-0242ac110002 UniProtKB:O75899 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Gamma-aminobutyric acid type B receptor subunit 2) DrugCentral uuid:3276e2ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:32770842-7972-11ec-93d9-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.523']} DrugCentral uuid:327731f0-7972-11ec-93d9-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:32775afe-7972-11ec-93d9-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:32778416-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3277adec-7972-11ec-93d9-0242ac110002 UniProtKB:O08532 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3277d70e-7972-11ec-93d9-0242ac110002 UniProtKB:O77773 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:32780044-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.928']} DrugCentral uuid:327829de-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3278530a-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:32787c2c-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3278a53a-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3278ceca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3278f7ce-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:327920e6-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:327949fe-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:327974d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:32799efe-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:3279c816-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3279f14c-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:327a1abe-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:327a4502-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:327a6e2e-7972-11ec-93d9-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:327a973c-7972-11ec-93d9-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is blocker of Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:327ac0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is negative allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:327af1b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:327af1b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:327af1b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:327b32dc-7972-11ec-93d9-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:327b5cda-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:327b85de-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:327baee2-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:327bd84a-7972-11ec-93d9-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:327c0144-7972-11ec-93d9-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:327c2a48-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:327c4eec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Kinase (Thymidine kinase) DrugCentral uuid:327c7458-7972-11ec-93d9-0242ac110002 UniProtKB:Q13255 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:327c9d7a-7972-11ec-93d9-0242ac110002 UniProtKB:P41594 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:327cc67e-7972-11ec-93d9-0242ac110002 UniProtKB:P10210 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Enzyme (Capsid scaffolding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:327cef82-7972-11ec-93d9-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:327d1a98-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganirelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:327d3f50-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:327d694e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:327d9658-7972-11ec-93d9-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:327d9658-7972-11ec-93d9-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:327dca24-7972-11ec-93d9-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:327dca24-7972-11ec-93d9-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:327dfd5a-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:327dfd5a-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:327e3284-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:327e5c8c-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:327e85b8-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:327eaeda-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:327ed806-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:327f0434-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:327f2d24-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:327f5632-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:327f7fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:327fa89e-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:327fd2ec-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:327ffbfa-7972-11ec-93d9-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:328025c6-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:32804ede-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:328077f6-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3280a10e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3280cb5c-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3280f46a-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:32811d82-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:32814780-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:328170f2-7972-11ec-93d9-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:32819a0a-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3281c336-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3281ecf8-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:32821610-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:32823f32-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3282684a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3282925c-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3282bb6a-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3282e482-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:32830db8-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3283370c-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3283601a-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:32838a22-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3283b34e-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3283dd06-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:328406c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32842fd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:328458f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:32848328-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3284ac54-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3284d580-7972-11ec-93d9-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3284ff92-7972-11ec-93d9-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:328528a0-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:328552a8-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:32857bd4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3285a58c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3285cfe4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3285f906-7972-11ec-93d9-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:32862232-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:32864e38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:328679f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3286a306-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3286cc32-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3286f59a-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:32871ec6-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:328747e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:328771aa-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32879acc-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3287c3e4-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3287ecf2-7972-11ec-93d9-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3288181c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:328841f2-7972-11ec-93d9-0242ac110002 UniProtKB:P31152 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:32886b14-7972-11ec-93d9-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32889436-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:3288bd8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3288e71a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:32891032-7972-11ec-93d9-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3289395e-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:32896424-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:32898d50-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:3289b668-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3289e0d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:328a0abe-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:328a33d6-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:328a5cf8-7972-11ec-93d9-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:328a8656-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:328aaf78-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:328ad8ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:328b01bc-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:328b2b7e-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Enzyme (Thymidylate synthase) DrugCentral uuid:328b504a-7972-11ec-93d9-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:328b7516-7972-11ec-93d9-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:328b99d8-7972-11ec-93d9-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:328bbfa8-7972-11ec-93d9-0242ac110002 UniProtKB:P30085 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Kinase (UMP-CMP kinase) DrugCentral uuid:328bed66-7972-11ec-93d9-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:328bed66-7972-11ec-93d9-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:328bed66-7972-11ec-93d9-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:328c2a60-7972-11ec-93d9-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Lipoprotein lipase) DrugCentral uuid:328c4f7c-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:328c788a-7972-11ec-93d9-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:328ca1a2-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.523']} DrugCentral uuid:328ccae2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:328cf4ae-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:328d1dd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:328d46de-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:328d70d2-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:328d9710-7972-11ec-93d9-0242ac110002 UniProtKB:P72525 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) DrugCentral uuid:328dbbdc-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestodene targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:328de080-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestodene targets Enzyme (Cytochrome P450 3A5) DrugCentral uuid:328e0542-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1292 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestrinone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:328e2ed2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12882 biolink:molecularly_interacts_with DrugCentral:1293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gimeracil is inhibitor of Enzyme (Dihydropyrimidine dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:328e57e0-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glafenine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:328e80e4-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glafenine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:328eade4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:328eade4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:328ee7c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.046']} DrugCentral uuid:328ee7c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.046']} DrugCentral uuid:328f20ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:328f20ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:328f5bcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.222']} DrugCentral uuid:328f5bcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.222']} DrugCentral uuid:328f95ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:328f95ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:328fcf12-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:328fcf12-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:329008ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glipizide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.097']} DrugCentral uuid:329008ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glipizide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.097']} DrugCentral uuid:329041f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliquidone is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:329041f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliquidone is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:32907b38-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glisoxepide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.959']} DrugCentral uuid:32907b38-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glisoxepide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.959']} DrugCentral uuid:3290b206-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3290dc54-7972-11ec-93d9-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:3291058a-7972-11ec-93d9-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:32912fb0-7972-11ec-93d9-0242ac110002 UniProtKB:P39086 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:32915abc-7972-11ec-93d9-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:329183ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q13255 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3291acd8-7972-11ec-93d9-0242ac110002 UniProtKB:P00367 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate dehydrogenase 1, mitochondrial) DrugCentral uuid:3291d1f4-7972-11ec-93d9-0242ac110002 UniProtKB:P49448 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate dehydrogenase 2, mitochondrial) DrugCentral uuid:3291f6a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:32921fc4-7972-11ec-93d9-0242ac110002 UniProtKB:P41594 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:329248d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14833 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:32927276-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:32929b98-7972-11ec-93d9-0242ac110002 UniProtKB:Q13002 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3292c492-7972-11ec-93d9-0242ac110002 UniProtKB:Q13003 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3292edbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q14831 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:3293179e-7972-11ec-93d9-0242ac110002 UniProtKB:O15303 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:329340b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q14416 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:329369b0-7972-11ec-93d9-0242ac110002 UniProtKB:P43003 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:329392d2-7972-11ec-93d9-0242ac110002 UniProtKB:P43004 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:3293bc94-7972-11ec-93d9-0242ac110002 UniProtKB:P43005 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3293e5ac-7972-11ec-93d9-0242ac110002 UniProtKB:P19491 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:32940ec4-7972-11ec-93d9-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.595']} DrugCentral uuid:329437dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q16099 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.738']} DrugCentral uuid:3294616c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14832 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid is agonist of GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:32948a98-7972-11ec-93d9-0242ac110002 UniProtKB:O00222 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid is agonist of GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3294b482-7972-11ec-93d9-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3294ded0-7972-11ec-93d9-0242ac110002 UniProtKB:P42260 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:32950856-7972-11ec-93d9-0242ac110002 UniProtKB:P22756 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:32953182-7972-11ec-93d9-0242ac110002 UniProtKB:P31423 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:32955a72-7972-11ec-93d9-0242ac110002 UniProtKB:P35349 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:32958420-7972-11ec-93d9-0242ac110002 UniProtKB:P19490 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3295ad2e-7972-11ec-93d9-0242ac110002 UniProtKB:P19492 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3295d6b4-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:3295ffb8-7972-11ec-93d9-0242ac110002 UniProtKB:P42264 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.31']} DrugCentral uuid:32962916-7972-11ec-93d9-0242ac110002 UniProtKB:Q03469 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate racemase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:32965242-7972-11ec-93d9-0242ac110002 UniProtKB:P70579 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:32967b5a-7972-11ec-93d9-0242ac110002 UniProtKB:P47743 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3296a454-7972-11ec-93d9-0242ac110002 UniProtKB:P31424 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3296d0d2-7972-11ec-93d9-0242ac110002 UniProtKB:P23385 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3296f9d6-7972-11ec-93d9-0242ac110002 UniProtKB:P31421 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:329722d0-7972-11ec-93d9-0242ac110002 UniProtKB:P31422 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:32974c7e-7972-11ec-93d9-0242ac110002 UniProtKB:P56068 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate racemase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:329775aa-7972-11ec-93d9-0242ac110002 UniProtKB:O35921 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:32979eae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:1311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:3297c7d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2Q3 biolink:molecularly_interacts_with DrugCentral:1312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutathione targets Enzyme (Glutathione S-transferase kappa 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3297f8cc-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:3297f8cc-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:3297f8cc-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:32983292-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:32985b8c-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:329886de-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.795']} DrugCentral uuid:3298b1cc-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3298db0c-7972-11ec-93d9-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:32990816-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:32990816-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:32993df4-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:329966f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:32999010-7972-11ec-93d9-0242ac110002 UniProtKB:Q96P20 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Unclassified (NACHT, LRR and PYD domains-containing protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3299b978-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:3299e29a-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Nuclear other (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:329a0fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ESQ5 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Ion channel (Sur1-Trpm4; Sulfonylurea receptor 1 - Transient receptor potential melastatin 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:329a0fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ESQ5 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Ion channel (Sur1-Trpm4; Sulfonylurea receptor 1 - Transient receptor potential melastatin 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:329a4906-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.523']} DrugCentral uuid:329a4906-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.523']} DrugCentral uuid:329a7ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:329aa7d4-7972-11ec-93d9-0242ac110002 UniProtKB:P48067 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Transporter (Sodium- and chloride-dependent glycine transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:329ae7b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:329ae7b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:329ae7b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:329ae7b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:329ae7b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:329ae7b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:329ae7b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:329b5972-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:329b832a-7972-11ec-93d9-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:329badd2-7972-11ec-93d9-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:329bd6e0-7972-11ec-93d9-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:329c0070-7972-11ec-93d9-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:329c2a0a-7972-11ec-93d9-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:1327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 goserelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:329c4f12-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 goserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:329c73fc-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:329c9d00-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:329cc62c-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:329cef58-7972-11ec-93d9-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:329d185c-7972-11ec-93d9-0242ac110002 UniProtKB:Q07820 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Induced myeloid leukemia cell differentiation protein Mcl-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:329d416a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:329d6ac8-7972-11ec-93d9-0242ac110002 UniProtKB:P00346 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:329d93c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q0PJ46 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Lactate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:329dbc9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6VVP7 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:329de58e-7972-11ec-93d9-0242ac110002 UniProtKB:P11708 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:329e1022-7972-11ec-93d9-0242ac110002 UniProtKB:P00338 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (L-lactate dehydrogenase A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:329e393a-7972-11ec-93d9-0242ac110002 UniProtKB:Q92843 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Apoptosis regulator Bcl-W) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:329e6248-7972-11ec-93d9-0242ac110002 UniProtKB:P52732 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Kinesin-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:329e8b56-7972-11ec-93d9-0242ac110002 UniProtKB:P11166 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Transporter (Solute carrier family 2, facilitated glucose transporter member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:329eb4be-7972-11ec-93d9-0242ac110002 UniProtKB:P29372 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (DNA-3-methyladenine glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:329eddc2-7972-11ec-93d9-0242ac110002 UniProtKB:P07195 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (L-lactate dehydrogenase B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:329f06c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:329f2fca-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:329f5950-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:329f8326-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:329faff4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:329faff4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:329feb22-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:329feb22-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:32a0202e-7972-11ec-93d9-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:32a04928-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:32a072ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:32a09f7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:32a09f7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:32a0d2a8-7972-11ec-93d9-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:32a0d2a8-7972-11ec-93d9-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:32a101ce-7972-11ec-93d9-0242ac110002 UniProtKB:P10875 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Structural (Tubulin beta chain) DrugCentral uuid:32a126f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:32a1512e-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:32a181ee-7972-11ec-93d9-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:32a181ee-7972-11ec-93d9-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:32a181ee-7972-11ec-93d9-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:32a1be0c-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guaiacol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:32a1e7f6-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guaiacol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:32a21118-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanadrel is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:32a235a8-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanadrel targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:32a25ac4-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:32a27f7c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:32a2a420-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:32a2c8ce-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:32a2edae-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:32a3125c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1D adrenergic receptor) DrugCentral uuid:32a3370a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:32a35cc6-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.065']} DrugCentral uuid:32a38778-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:32a3b27a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:32a3db88-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.926']} DrugCentral uuid:32a40464-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:32a42dc2-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:32a456d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:32a47fc0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:32a4a8e2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.164']} DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a56944-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a76334-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32a8280a-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ulobetasol propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:32a84cc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halofantrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:32a87620-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:32a89f2e-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.003']} DrugCentral uuid:32a8c83c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:32a8f15e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:32a91ce2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.947']} DrugCentral uuid:32a945f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:32a96ecc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:32a99834-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:32a9c142-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:32a9ea50-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:32aa135e-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:32aa3cc6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:32aa6674-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:32aa8f78-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:32aab890-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:32aae2a2-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:32ab0bba-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:32ab34dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:32ab5df4-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:32ab8766-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32abb07e-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:32abda7c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:32ac0380-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.999']} DrugCentral uuid:32ac2d06-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:32ac560a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:32ac7f22-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.182']} DrugCentral uuid:32aca984-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.569']} DrugCentral uuid:32acd5e4-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:32acff60-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:32ad2878-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:32ad51f4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:32ad83d6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:32ad83d6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:32ad83d6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:32adc4e0-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.648']} DrugCentral uuid:32adee5c-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:32ae1760-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:32ae4082-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:32ae6972-7972-11ec-93d9-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:32ae9406-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.305']} DrugCentral uuid:32aebd28-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:32aee62c-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:32af0f3a-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.76']} DrugCentral uuid:32af3974-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:32af6296-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:32af8b90-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:32afb61a-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:32afdf3c-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:32b0085e-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:32b03176-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:32b05c6e-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:32b085ae-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:32b0aeb2-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:32b0d7c0-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:32b10146-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:32b12a54-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:32b1536c-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32b17d4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:32b1a6b4-7972-11ec-93d9-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:32b1cfea-7972-11ec-93d9-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:32b1f902-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:32b22300-7972-11ec-93d9-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:32b24c2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:32b2753a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:32b29e3e-7972-11ec-93d9-0242ac110002 UniProtKB:P50129 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:32b2c7b0-7972-11ec-93d9-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:32b2f0c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:32b319b8-7972-11ec-93d9-0242ac110002 UniProtKB:P62744 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (AP-2 complex subunit sigma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:32b35342-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:32b35342-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:32b35342-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:32b35342-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:32b35342-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:32b3b972-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32b3b972-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32b3b972-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32b3b972-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32b413e0-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:32b413e0-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:32b413e0-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:32b413e0-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:32b46962-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:32b46962-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:32b46962-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:32b4afc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:32b4afc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:32b4f436-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32b4f436-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32b4f436-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32b4f436-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32b4f436-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32b555e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32b555e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32b555e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32b59e9a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:32b59e9a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:32b59e9a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:32b5fd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32b5fd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32b5fd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32b5fd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32b5fd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32b5fd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32b5fd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32b5fd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:32b6829c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:32b6829c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:32b6829c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:32b6c540-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:32b6ee30-7972-11ec-93d9-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:32b717a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:32b740ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32b769d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q60493 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (Zinc finger protein 664) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:32b79308-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:32b7bdce-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halopredone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:32b7e2ae-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:32b80bc6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.339']} DrugCentral uuid:32b834e8-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.366']} DrugCentral uuid:32b85ea0-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.561']} DrugCentral uuid:32b88844-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:32b8b148-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:32b8dace-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:32b9045e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:32b92e70-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:32b9576a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.231']} DrugCentral uuid:32b98136-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.805']} DrugCentral uuid:32b9aa3a-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:32b9d334-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.338']} DrugCentral uuid:32b9fc56-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:32ba2654-7972-11ec-93d9-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:32ba4f62-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:32ba7424-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:32ba98fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:32babe2a-7972-11ec-93d9-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:32bae2f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:32bb0b96-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:32bb0b96-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bb75fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:32bc3b60-7972-11ec-93d9-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin is activator of Secreted (Antithrombin-III) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:32bc6478-7972-11ec-93d9-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.14']} DrugCentral uuid:32bc8dfe-7972-11ec-93d9-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin targets Unclassified (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.14']} DrugCentral uuid:32bcb6ee-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:32bce006-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:32bd0914-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:32bd3448-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:32bd5d74-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:32bd865a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:32bdaf40-7972-11ec-93d9-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:32bdd89e-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:32be0198-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:32be3da2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:32be3da2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:32be3da2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:32be3da2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:32be3da2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:32be3da2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:32be970c-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.212']} DrugCentral uuid:32bec07e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.191']} DrugCentral uuid:32bee982-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.043']} DrugCentral uuid:32bf1510-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.686']} DrugCentral uuid:32bf3e28-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.636']} DrugCentral uuid:32bf672c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.441']} DrugCentral uuid:32bf90b2-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.618']} DrugCentral uuid:32bfb9ca-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.994']} DrugCentral uuid:32bfe3c8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.442']} DrugCentral uuid:32c00cea-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:32c03774-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.521']} DrugCentral uuid:32c06096-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:32c0899a-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.882']} DrugCentral uuid:32c0b2bc-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.126']} DrugCentral uuid:32c0dca6-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.911']} DrugCentral uuid:32c105a0-7972-11ec-93d9-0242ac110002 UniProtKB:P06149 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (D-lactate dehydrogenase) DrugCentral uuid:32c12a62-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.614']} DrugCentral uuid:32c1537a-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.459']} DrugCentral uuid:32c17d1e-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.479']} DrugCentral uuid:32c1a60e-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:32c1cf08-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.605']} DrugCentral uuid:32c1f802-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.057']} DrugCentral uuid:32c22174-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:32c24aaa-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.479']} DrugCentral uuid:32c273c2-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.708']} DrugCentral uuid:32c29d98-7972-11ec-93d9-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) DrugCentral uuid:32c2c2a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:32c2ebae-7972-11ec-93d9-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:32c314b2-7972-11ec-93d9-0242ac110002 UniProtKB:P11142 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Heat shock cognate 71 kDa protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:32c33e24-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMV8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Heat shock 70 kDa protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:32c36728-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:32c39018-7972-11ec-93d9-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:32c3b908-7972-11ec-93d9-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:32c3e37e-7972-11ec-93d9-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:32c40d22-7972-11ec-93d9-0242ac110002 UniProtKB:Q6IQ20 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene is inhibitor of Unclassified (N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:32c4363a-7972-11ec-93d9-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:32c45f48-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:32c4852c-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:32c4ae4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:32c4db4e-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:32c4db4e-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:32c514d8-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:32c514d8-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:32c54db8-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:32c54db8-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:32c58e40-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:32c58e40-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:32c58e40-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:32c58e40-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:32c5dd6e-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:32c60668-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:32c62f6c-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexestrol is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:32c6619e-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:32c6619e-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:32c6619e-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:32c6a2f8-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:32c6a2f8-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:32c6a2f8-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:32c6e4c0-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:32c6e4c0-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:32c6e4c0-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:32c72750-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:32c72750-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:32c72750-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:32c768d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:32c768d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:32c768d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:32c7ab26-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:32c7d006-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:32c7f93c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:32c823c6-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:32c84d1a-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:32c87628-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:32c8a706-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:32c8a706-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:32c8a706-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:32c8e8b0-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:32c911b4-7972-11ec-93d9-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:32c93ab8-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:32c96484-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine is agonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:32c98d9c-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:32c9b696-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:32c9df86-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.508']} DrugCentral uuid:32ca0c72-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:32ca3896-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:32ca650a-7972-11ec-93d9-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:32ca8e40-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:32cab71c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:32cae02a-7972-11ec-93d9-0242ac110002 UniProtKB:P58406 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:32cb0956-7972-11ec-93d9-0242ac110002 UniProtKB:Q91ZY2 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:32cb32d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q91ZY1 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:32cb5bcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.84']} DrugCentral uuid:32cb84d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q91ZY3 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:32cbadfc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histidine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:32cbd91c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:32cc0248-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:32cc2b7e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:32cc5482-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:32cc7e9e-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:32cca7b6-7972-11ec-93d9-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hycanthone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:32ccd0ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:32ccf9aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:32cd1ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 1) DrugCentral uuid:32cd436a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:32cd680e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBC3 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 3B) DrugCentral uuid:32cd8cda-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:32cdb7dc-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.438']} DrugCentral uuid:32cde0ea-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:32ce0a0c-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:32ce3324-7972-11ec-93d9-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32ce5cdc-7972-11ec-93d9-0242ac110002 UniProtKB:B0LPN4 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Ion channel (Ryanodine receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.152']} DrugCentral uuid:32ce86da-7972-11ec-93d9-0242ac110002 UniProtKB:Q92736 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine is blocker of Ion channel (Ryanodine receptor 2) DrugCentral uuid:32ceab92-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:32ced536-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.01']} DrugCentral uuid:32cefe26-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:32cf273e-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:32cf4c0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:32cf71f8-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:32cf9e1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:32cfc798-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:32cff204-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:32d01bda-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:32d045b0-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocodone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:32d06ec8-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocodone is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:32d097fe-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortamate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:32d0bd42-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:32d0e664-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Cytosolic other (Annexin A1) DrugCentral uuid:32d10b3a-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.95']} DrugCentral uuid:32d13448-7972-11ec-93d9-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:32d15dec-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.881']} DrugCentral uuid:32d1872c-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:32d1b04e-7972-11ec-93d9-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.37']} DrugCentral uuid:32d1d98e-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone cypionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:32d1fefa-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroflumethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.37']} DrugCentral uuid:32d22808-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:32d25134-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:32d27a56-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:32d2b02a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:32d2b02a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:32d2b02a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:32d2b02a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:32d2fd1e-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.1']} DrugCentral uuid:32d326ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:32d3500c-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.529']} DrugCentral uuid:32d3791a-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:32d3a232-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:32d3ccbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:32d3f19c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:32d41aa0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.81']} DrugCentral uuid:32d443c2-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:32d46d48-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:32d4966a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:32d4bf8c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:32d4e89a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:32d51388-7972-11ec-93d9-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:32d5384a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:32d5618a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYK1 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine is antagonist of Membrane receptor (Toll-like receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:32d58c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine is antagonist of Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:32d5b608-7972-11ec-93d9-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:32d5df2a-7972-11ec-93d9-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:1398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxystilbamidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:32d60806-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:32d6316e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:32d65b76-7972-11ec-93d9-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:32d6804c-7972-11ec-93d9-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:32d6a504-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:32d6cec6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:32d6f7d4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:32d7210a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:32d74a22-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.409']} DrugCentral uuid:32d77402-7972-11ec-93d9-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:32d79d06-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:32d7c600-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:32d7eee6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:32d81862-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:32d8418e-7972-11ec-93d9-0242ac110002 UniProtKB:P37058 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:32d86a92-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:32d89382-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:32d8bd76-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:32d8e698-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:32d90fc4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:32d93986-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:32d962c6-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:32d98be8-7972-11ec-93d9-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:32d9b4f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q02769 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:32d9de5e-7972-11ec-93d9-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:32da0758-7972-11ec-93d9-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:32da3052-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:32da5a32-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:32da8598-7972-11ec-93d9-0242ac110002 UniProtKB:Q08493 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:32daaea6-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:32dad7b4-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:32db00c2-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:32db2a8e-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:32db5392-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:32db7dcc-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:32dba2a2-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:32dbcc00-7972-11ec-93d9-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:32dbf572-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:32dc1e62-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:32dc48c4-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:32dc7448-7972-11ec-93d9-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:32dc9d4c-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:32dcc65a-7972-11ec-93d9-0242ac110002 UniProtKB:P02769 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:32dceff4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:32dd18ee-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:32dd41e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:32dd6ede-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:32dd6ede-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:32dda444-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N695 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Transporter (Sodium-coupled monocarboxylate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:32ddcd52-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VD48 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:32ddf656-7972-11ec-93d9-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is blocker of Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.53']} DrugCentral uuid:32de20c2-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:32de506a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:32de506a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:32de858a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibutilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:32deaeac-7972-11ec-93d9-0242ac110002 UniProtKB:O75907 biolink:molecularly_interacts_with DrugCentral:1413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icosapent ethyl is inhibitor of Enzyme (Diacylglycerol O-acyltransferase 1) DrugCentral uuid:32ded404-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:32def8da-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:32df1d9c-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:32df4254-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:32df6bb2-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:32df94ac-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:32dfbdb0-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:32dfe6be-7972-11ec-93d9-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:1417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idoxuridine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:32e010f8-7972-11ec-93d9-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:1417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idoxuridine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:32e03a06-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:32e06300-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.41']} DrugCentral uuid:32e08c5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:32e0b56c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:32e0de5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:32e10774-7972-11ec-93d9-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:32e13212-7972-11ec-93d9-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:32e15b16-7972-11ec-93d9-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:32e18406-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32e1adaa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:32e1d9ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:32e202e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:32e22be0-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.99']} DrugCentral uuid:32e259b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:32e259b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:32e296f2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:32e296f2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:32e296f2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:32e2d81a-7972-11ec-93d9-0242ac110002 UniProtKB:Q00960 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate [NMDA] receptor subunit epsilon 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:32e30196-7972-11ec-93d9-0242ac110002 UniProtKB:Q60490 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Unclassified (3-beta-hydroxysteroid-delta(8),delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.57']} DrugCentral uuid:32e32ac2-7972-11ec-93d9-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:32e353c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:32e37cde-7972-11ec-93d9-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:32e3a722-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:32e3d012-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:32e3f902-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:32e421fc-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:32e44b5a-7972-11ec-93d9-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:32e47472-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:32e49d76-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:32e4c670-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:32e4f000-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:32e51918-7972-11ec-93d9-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:32e5421c-7972-11ec-93d9-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:32e56c24-7972-11ec-93d9-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:32e59514-7972-11ec-93d9-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:32e5be18-7972-11ec-93d9-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:32e5e708-7972-11ec-93d9-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:32e61160-7972-11ec-93d9-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:32e63a46-7972-11ec-93d9-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:32e6632c-7972-11ec-93d9-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:32e68c12-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:32e6b570-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:32e6de6a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:32e708a4-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:32e731bc-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:32e75cdc-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:32e7818a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:32e7aa70-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:32e7d36a-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:32e7fd68-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:32e82680-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:32e84f70-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:32e87914-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:32e8a218-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:32e8cb30-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:32e8f416-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:32e91ee6-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:32e947f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:32e9710c-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:32e999fc-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:32e9c364-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:32e9ec54-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:32ea1684-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:32ea3f74-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:32ea68dc-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:32ea91e0-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:32eabae4-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:32eae3de-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:32eb0e54-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:32eb3758-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:32eb6066-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:32eb89d8-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:32ebb2dc-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:32ebdbd6-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:32ec04c6-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:32ec2e38-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:32ec5728-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:32ec8018-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:32eca912-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:32ecd4e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:32ecfdfe-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:32ed2856-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:32ed515a-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:32ed7ac2-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:32eda3c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:32edccca-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:32edf6aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:32ee2080-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:32ee497a-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:32ee7288-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:32ee9df8-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:32eec968-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:32eef26c-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:32ef1b70-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:32ef44ba-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:32ef6dbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q15046 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Lysine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:32ef96b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:32efbfb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:32efe906-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:32f01228-7972-11ec-93d9-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:32f03b0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:32f064ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:32f09130-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:32f0baa2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:32f0e388-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:32f10ce6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:32f135ea-7972-11ec-93d9-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.97']} DrugCentral uuid:32f15ee4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:32f187ca-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:32f1b132-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:32f1da2c-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:32f20326-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:32f22cf2-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:32f2595c-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:32f28616-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:32f28616-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:32f2bf00-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:32f2bf00-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:32f2f844-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:32f2f844-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:32f32eb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q05030 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:32f357b2-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:32f38106-7972-11ec-93d9-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Penicillin-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:32f3aa00-7972-11ec-93d9-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Penicillin-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:32f3d304-7972-11ec-93d9-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:32f3fbfe-7972-11ec-93d9-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:32f43f92-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:32f43f92-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:32f43f92-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:32f43f92-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:32f43f92-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:32f43f92-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:32f43f92-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:32f4a2fc-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:32f4cc82-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.284']} DrugCentral uuid:32f4f568-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:32f51ef8-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.854']} DrugCentral uuid:32f54874-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.432']} DrugCentral uuid:32f57178-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:32f59b76-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.825']} DrugCentral uuid:32f5c47a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:32f5ef40-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.495']} DrugCentral uuid:32f6186c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:32f64170-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.412']} DrugCentral uuid:32f66a92-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.614']} DrugCentral uuid:32f693f0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:32f6bd12-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:32f6e616-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:32f70f2e-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:32f73896-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.081']} DrugCentral uuid:32f761b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.071']} DrugCentral uuid:32f78abc-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:32f7b3b6-7972-11ec-93d9-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:32f7de04-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:32f806fe-7972-11ec-93d9-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:32f8300c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:32f85988-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:32f883cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:32f8acd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:32f8d5de-7972-11ec-93d9-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:32f8ff50-7972-11ec-93d9-0242ac110002 UniProtKB:P34968 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:32f92872-7972-11ec-93d9-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:32f9519e-7972-11ec-93d9-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:32f97aa2-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:32f9a626-7972-11ec-93d9-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:32f9cf3e-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:32f9f838-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:32fa3870-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:32fa3870-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:32fa3870-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:32fa3870-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:32fa3870-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:32fa3870-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:32fa3870-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:32fab8fe-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:32fab8fe-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:32fab8fe-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:32fab8fe-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:32fab8fe-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fb4440-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:32fc1aaa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:32fc1aaa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:32fc1aaa-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:32fc6c80-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:32fc6c80-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:32fc6c80-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:32fc6c80-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:32fc6c80-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:32fcce82-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:32fcce82-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:32fcce82-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:32fd1798-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:32fd1798-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:32fd1798-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:32fd63e2-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:32fd63e2-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:32fd63e2-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:32fda532-7972-11ec-93d9-0242ac110002 UniProtKB:P48545 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:32fdce2c-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:32fdf7bc-7972-11ec-93d9-0242ac110002 UniProtKB:P17405 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Enzyme (Sphingomyelin phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:32fe20c0-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:32fe4aaa-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:32fe7430-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:32fe9d66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYK1 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod is agonist of Membrane receptor (Toll-like receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:32fec674-7972-11ec-93d9-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:32feef8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8MTZ4 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid targets Unclassified (Vacuolar-type proton translocating pyrophosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:32ff1a52-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:32ff436a-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indalpine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:32ff6c82-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:32ff95ae-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.54']} DrugCentral uuid:32ffbf0c-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:32ffe824-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:33001146-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:33003a72-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:330063e4-7972-11ec-93d9-0242ac110002 UniProtKB:P51787 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Ion channel (Potassium voltage-gated channel subfamily KQT member 1) DrugCentral uuid:330088b0-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3300b1aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:3300dab8-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:33010506-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:33012f36-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:33015858-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.535']} DrugCentral uuid:330181de-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:3301ab00-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3301d418-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indecainide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:3301f8c6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indenolol targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:33021e0a-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indenolol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:330242d6-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:33026c98-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.222']} DrugCentral uuid:330295b0-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.733']} DrugCentral uuid:3302bfe0-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3302e98e-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:3303129c-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:33033bb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:33036526-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:33038df8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.27']} DrugCentral uuid:3303b6f2-7972-11ec-93d9-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:3303e00a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:3304097c-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3304328a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indobufen targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:33045738-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indobufen targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:33047c04-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3304a7ec-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3304d0fa-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:3304f9fe-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:33052316-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:33054c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:33057578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BPW9 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:33059e72-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3305c7ee-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:3305f0fc-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:330619f6-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:330642fa-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.691']} DrugCentral uuid:33066d3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:33069746-7972-11ec-93d9-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3306c04a-7972-11ec-93d9-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3306e930-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:330712ac-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:33073cbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.19']} DrugCentral uuid:330765c2-7972-11ec-93d9-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:33078ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3307b82e-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3307e15a-7972-11ec-93d9-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:33080a5e-7972-11ec-93d9-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3308348e-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:33085dc4-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:330886d2-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:3308b3be-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3308b3be-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3308eda2-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3308eda2-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:330926a0-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase (cyclooxygenase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:330926a0-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase (cyclooxygenase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:33095bca-7972-11ec-93d9-0242ac110002 UniProtKB:P29477 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3309853c-7972-11ec-93d9-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:3309ae4a-7972-11ec-93d9-0242ac110002 UniProtKB:P17516 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:3309d744-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:330a0052-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:330a2cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:330a56d8-7972-11ec-93d9-0242ac110002 UniProtKB:P08659 biolink:molecularly_interacts_with DrugCentral:1442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoprofen targets Unclassified (Luciferin 4-monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:330a7fdc-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:330aa98a-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:330ad2b6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:330afbf6-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:330b250e-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:330b4ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:330b77c0-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:330ba0ec-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:330bca04-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:330bfc2c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:330bfc2c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:330bfc2c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:330c4524-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:330c4524-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:330c4524-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:330c8804-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:330cb112-7972-11ec-93d9-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase I, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:330cda0c-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:330d02fc-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.278']} DrugCentral uuid:330d2cbe-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.724']} DrugCentral uuid:330d55ae-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.609']} DrugCentral uuid:330d7eb2-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.804']} DrugCentral uuid:330da7ac-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.067']} DrugCentral uuid:330dd330-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.279']} DrugCentral uuid:330dfd1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.439']} DrugCentral uuid:330e261e-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.043']} DrugCentral uuid:330e4f9a-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.532']} DrugCentral uuid:330e789e-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:330ea18e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:330eca9c-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:330ef44a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.292']} DrugCentral uuid:330f1dbc-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.181']} DrugCentral uuid:330f46ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:330f6fec-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:330f9a26-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:330fc33e-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.74']} DrugCentral uuid:330fec60-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:33101564-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipriflavone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.531']} DrugCentral uuid:33103ee0-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipriflavone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:331067ee-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:33109106-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.899']} DrugCentral uuid:3310ba14-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:3310e3c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.185']} DrugCentral uuid:33110cda-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:331135e8-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:33115fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:331188f4-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3311b220-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3311db38-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:33120586-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3312327c-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:3312327c-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:331270a2-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:331270a2-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:331270a2-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:3312b288-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3312dba0-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:33130062-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:33132966-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:33135008-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.336']} DrugCentral uuid:3313792a-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:33139dd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:3313c286-7972-11ec-93d9-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:3313e798-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:331410ce-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan is inhibitor of Enzyme (DNA topoisomerase 1) DrugCentral uuid:3314359a-7972-11ec-93d9-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.218']} DrugCentral uuid:33145eb2-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:33148842-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:3314b16e-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3314da72-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:33150420-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:33152d92-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:33155682-7972-11ec-93d9-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:1483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irofulven targets Kinase (Serine/threonine-protein kinase Chk2) DrugCentral uuid:33157bd0-7972-11ec-93d9-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:1486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isepamicin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.87']} DrugCentral uuid:3315a574-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1490 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isocarboxazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:3315ca4a-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1490 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isocarboxazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:3315f010-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoetarine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:33161928-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.109']} DrugCentral uuid:3316438a-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:33166860-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:33168d36-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:3316b202-7972-11ec-93d9-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:3316d6e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:33170298-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:33170298-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33176b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33182f56-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3318586e-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:33188190-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.15']} DrugCentral uuid:3318aa8a-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:3318d578-7972-11ec-93d9-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3318fe86-7972-11ec-93d9-0242ac110002 UniProtKB:Q29550 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Liver carboxylesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:33192776-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:331950b6-7972-11ec-93d9-0242ac110002 UniProtKB:P9WIE4 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Catalase-peroxidase) DrugCentral uuid:3319758c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:33199e90-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3319c76c-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3319f0ca-7972-11ec-93d9-0242ac110002 UniProtKB:P9WNX1 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:331a19ec-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:331a4304-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:331a6bfe-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:331a9700-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:331ac086-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:331ae980-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:331b128e-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.752']} DrugCentral uuid:331b3c46-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:331b6540-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:331b8e3a-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:331bb73e-7972-11ec-93d9-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:331be3e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331c0cf2-7972-11ec-93d9-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331c360a-7972-11ec-93d9-0242ac110002 UniProtKB:P04274 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:331c617a-7972-11ec-93d9-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:331c8a92-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:331cb3a0-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:331cdcd6-7972-11ec-93d9-0242ac110002 UniProtKB:P59533 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 38) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331d076a-7972-11ec-93d9-0242ac110002 UniProtKB:P59534 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 39) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331d306e-7972-11ec-93d9-0242ac110002 UniProtKB:P59535 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 40) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331d597c-7972-11ec-93d9-0242ac110002 UniProtKB:P59536 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 41) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331d8294-7972-11ec-93d9-0242ac110002 UniProtKB:P59537 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 43) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331dac92-7972-11ec-93d9-0242ac110002 UniProtKB:P59538 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 31) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331dd5a0-7972-11ec-93d9-0242ac110002 UniProtKB:P59539 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 45) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331dfea4-7972-11ec-93d9-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331e279e-7972-11ec-93d9-0242ac110002 UniProtKB:P59541 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 30) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331e517e-7972-11ec-93d9-0242ac110002 UniProtKB:P59542 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 19) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331e7a82-7972-11ec-93d9-0242ac110002 UniProtKB:P59543 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331ea386-7972-11ec-93d9-0242ac110002 UniProtKB:P59544 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 50) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331ecd34-7972-11ec-93d9-0242ac110002 UniProtKB:P59551 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 60) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331ef642-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTR8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 42) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331f1f50-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYV7 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 16) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331f485e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331f71d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYV9 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 13) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331f9ad4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW0 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331fc3ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW1 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:331fecf0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW2 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:33201892-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW3 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:332042a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW4 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:33206bb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW5 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:332094c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW6 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3320be6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW7 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3320e77c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isopropamide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:33210d38-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isopropamide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:332131e6-7972-11ec-93d9-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:3321629c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3321629c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3321629c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3321629c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3321a6da-7972-11ec-93d9-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:3321d830-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3321d830-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3321d830-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3321d830-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:33221e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:3322473e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:332270d8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.628']} DrugCentral uuid:33229a04-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['8.229']} DrugCentral uuid:3322c2fe-7972-11ec-93d9-0242ac110002 UniProtKB:P08319 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (Alcohol dehydrogenase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:3322ec16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BPW9 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.523']} DrugCentral uuid:3323157e-7972-11ec-93d9-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (11-cis retinol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:33233e8c-7972-11ec-93d9-0242ac110002 UniProtKB:O14756 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (17-beta-hydroxysteroid dehydrogenase type 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:332367ae-7972-11ec-93d9-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin is inhibitor of Nuclear hormone receptor (Retinoic acid receptor beta) DrugCentral uuid:33238c8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.597']} DrugCentral uuid:3323b72c-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.335']} DrugCentral uuid:3323e21a-7972-11ec-93d9-0242ac110002 UniProtKB:P40220 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:33240b0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:332433fa-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1509 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:33245db2-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1509 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:332486a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:3324ab3c-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:3324d0e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3324fa6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3325236e-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:33254c90-7972-11ec-93d9-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:3325759e-7972-11ec-93d9-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3325a154-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JIS7 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3325ca4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01815 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:3325f3ca-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:33261d96-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.046']} DrugCentral uuid:33264686-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['9.246']} DrugCentral uuid:33266fa8-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:332698ac-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3326c20a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3326eb04-7972-11ec-93d9-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:33271412-7972-11ec-93d9-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:33273d02-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:33276804-7972-11ec-93d9-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:33279298-7972-11ec-93d9-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:3327bbb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33280458-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:33287e10-7972-11ec-93d9-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.678']} DrugCentral uuid:3328a78c-7972-11ec-93d9-0242ac110002 UniProtKB:P0A6R0 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Unclassified (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3328d086-7972-11ec-93d9-0242ac110002 UniProtKB:P29033 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Unclassified (Gap junction beta-2 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:3328f976-7972-11ec-93d9-0242ac110002 UniProtKB:C3TDZ2 biolink:molecularly_interacts_with DrugCentral:1520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bekanamycin targets Enzyme (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:33292270-7972-11ec-93d9-0242ac110002 UniProtKB:P0A6R0 biolink:molecularly_interacts_with DrugCentral:1520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bekanamycin targets Unclassified (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:33294c5a-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:33298c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:33298c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:33298c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:33298c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:33298c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:33298c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:33298c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:332a1554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:332a1554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:332a1554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:332a1554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:332a1554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:332a1554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:332a1554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:332a927c-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:332a927c-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:332a927c-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:332a927c-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:332ad782-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:332b01b2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:332b2ca0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki'} DrugCentral uuid:332b5798-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:332b8092-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:332baa54-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:332bd36c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:332bfc7a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:332c2592-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:332c4f22-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:332c7844-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:332ca166-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:332cca7e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.701']} DrugCentral uuid:332cf706-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:332d2064-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.747']} DrugCentral uuid:332d4968-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:332d7316-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:332d9c24-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:332dc51e-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:332dee40-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:332e17c6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:332e40de-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:332e69f6-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.903']} DrugCentral uuid:332e9304-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:332ebd84-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:332ee796-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:332f10cc-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:332f39ee-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.33']} DrugCentral uuid:332f63ba-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:332f8ce6-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:332fb5f4-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:332fdf7a-7972-11ec-93d9-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:33301026-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:33301026-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:33301026-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3330591e-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3330591e-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3330591e-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:33309cd0-7972-11ec-93d9-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3330c5f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BRU6 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3330eee2-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:333119b2-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:333142ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.585']} DrugCentral uuid:33316bd8-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:3331a06c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3331a06c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3331a06c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3331a06c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3331f972-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3331f972-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3331f972-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3331f972-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:333247b0-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.821']} DrugCentral uuid:333272e4-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:33329ca6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3332c5a0-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3332ef62-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:33331898-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:333341b0-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:33336abe-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.084']} DrugCentral uuid:3333943a-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.667']} DrugCentral uuid:3333bd5c-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.028']} DrugCentral uuid:3333e660-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:33340f5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.729']} DrugCentral uuid:33343a5c-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:33345f14-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:33348854-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3334b158-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:3334db24-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:333504aa-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:33352dae-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:333556c6-7972-11ec-93d9-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:33358056-7972-11ec-93d9-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3335a9c8-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:3335d2cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.665']} DrugCentral uuid:3335fdec-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'app Ki', 'has_quantitative_value': ['7.197']} DrugCentral uuid:33362a2e-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:333653b4-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:33367dc6-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3336a8a0-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3336d1ae-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.266']} DrugCentral uuid:3336fad0-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.897']} DrugCentral uuid:333723f2-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.211']} DrugCentral uuid:33374d82-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:33377690-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:33379f9e-7972-11ec-93d9-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.66']} DrugCentral uuid:3337c88e-7972-11ec-93d9-0242ac110002 UniProtKB:Q07973 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.506']} DrugCentral uuid:3337f53e-7972-11ec-93d9-0242ac110002 UniProtKB:P08686 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 21) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:33381eb0-7972-11ec-93d9-0242ac110002 UniProtKB:P15150 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 11B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:333847be-7972-11ec-93d9-0242ac110002 UniProtKB:P14137 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:3338720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q09128 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 24A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:33389b24-7972-11ec-93d9-0242ac110002 UniProtKB:P18125 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 7A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:3338c428-7972-11ec-93d9-0242ac110002 UniProtKB:Q64654 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 51) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:3338ed40-7972-11ec-93d9-0242ac110002 UniProtKB:P11715 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 17A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:333916c6-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:33393fde-7972-11ec-93d9-0242ac110002 UniProtKB:O35084 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:333968e2-7972-11ec-93d9-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:333991f0-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3339bc5c-7972-11ec-93d9-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.896']} DrugCentral uuid:3339e57e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:333a0f86-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:333a388a-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:333a622e-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:333a8f1a-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:333a8f1a-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:333ac43a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:333aedac-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.72']} DrugCentral uuid:333b16ba-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:333b3fd2-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.214']} DrugCentral uuid:333b68d6-7972-11ec-93d9-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:333b94aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:333bbdae-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.361']} DrugCentral uuid:333be6c6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:333c0fde-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:333c3554-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.839']} DrugCentral uuid:333c6056-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.047']} DrugCentral uuid:333c8982-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:333cb31c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.076']} DrugCentral uuid:333cdc3e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:333d0560-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.489']} DrugCentral uuid:333d2e78-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:333d58b2-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.509']} DrugCentral uuid:333d81d4-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.391']} DrugCentral uuid:333daae2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:333dd3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.016']} DrugCentral uuid:333dfdb2-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.359']} DrugCentral uuid:333e27a6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:333e50b4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.075']} DrugCentral uuid:333e79cc-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:333ea352-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.737']} DrugCentral uuid:333ecc74-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:333ef56e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:333f1e90-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.234']} DrugCentral uuid:333f4afa-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:333f741c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.117']} DrugCentral uuid:333f9d20-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.478']} DrugCentral uuid:333fc6ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.648']} DrugCentral uuid:333fefe6-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:33401908-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.894']} DrugCentral uuid:3340422a-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:33406b9c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:334094be-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.491']} DrugCentral uuid:3340bdd6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3340e6d0-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:33411222-7972-11ec-93d9-0242ac110002 UniProtKB:P47154 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (CAAX prenyl protease 1) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:33413b12-7972-11ec-93d9-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:33416402-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.046']} DrugCentral uuid:33418cf2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.245']} DrugCentral uuid:3341b6c8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:3341dfe0-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.642']} DrugCentral uuid:334208ee-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:33423350-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:33425c5e-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.771']} DrugCentral uuid:3342871a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:3342b42e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:3342b42e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:3342e4f8-7972-11ec-93d9-0242ac110002 UniProtKB:O00214 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.21']} DrugCentral uuid:33430dfc-7972-11ec-93d9-0242ac110002 UniProtKB:O00182 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.64']} DrugCentral uuid:33433700-7972-11ec-93d9-0242ac110002 UniProtKB:P17931 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.03']} DrugCentral uuid:33435fd2-7972-11ec-93d9-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:33438534-7972-11ec-93d9-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine is inhibitor of Polyprotein (Protein P) DrugCentral uuid:3343aa1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:3343d322-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:3343fc1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.839']} DrugCentral uuid:33442570-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:33444a46-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3344735e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:33449c76-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:3344c642-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:3344eb18-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:33451412-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.744']} DrugCentral uuid:33453de8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:334566d8-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:33458fd2-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3345c074-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3345c074-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3345c074-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3346032c-7972-11ec-93d9-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:33462c08-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1545 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 landiolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:334650d4-7972-11ec-93d9-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:33467b54-7972-11ec-93d9-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3346a480-7972-11ec-93d9-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3346cd84-7972-11ec-93d9-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3346f688-7972-11ec-93d9-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:33472022-7972-11ec-93d9-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:33474926-7972-11ec-93d9-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3347722a-7972-11ec-93d9-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide targets GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:33479b38-7972-11ec-93d9-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3347c4aa-7972-11ec-93d9-0242ac110002 UniProtKB:P30936 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3347edc2-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.275']} DrugCentral uuid:334816a8-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.473']} DrugCentral uuid:334840ce-7972-11ec-93d9-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:33486c8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCT1 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Phosphoethanolamine/phosphocholine phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:33489588-7972-11ec-93d9-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3348beb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3348ec7c-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:3348ec7c-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:33491bca-7972-11ec-93d9-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:33494500-7972-11ec-93d9-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:33496e2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:33499776-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:3349bc2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:3349e0dc-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:334a0ac6-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:334a358c-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:334a5eae-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:334a87c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (Solute carrier organic anion transporter family member 1B1) DrugCentral uuid:334aac7e-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:334ad64a-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:334aff58-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:334b285c-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:334b5174-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:334b7af0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:334ba41c-7972-11ec-93d9-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:334bcd16-7972-11ec-93d9-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:334bf746-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:334c228e-7972-11ec-93d9-0242ac110002 UniProtKB:O00750 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:334c4ba6-7972-11ec-93d9-0242ac110002 UniProtKB:O75747 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:334c74a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:334c9ea8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:334cc7b6-7972-11ec-93d9-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:1549 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine hydrochloride targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:334cf0ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q5T6X5 biolink:molecularly_interacts_with DrugCentral:1549 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine hydrochloride is agonist of GPCR (G-protein coupled receptor family C group 6 member A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:334d19d2-7972-11ec-93d9-0242ac110002 UniProtKB:O75746 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Calcium-binding mitochondrial carrier protein Aralar1) DrugCentral uuid:334d3ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P17174 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate aminotransferase, cytoplasmic) DrugCentral uuid:334d6374-7972-11ec-93d9-0242ac110002 UniProtKB:P45381 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartoacylase) DrugCentral uuid:334d8818-7972-11ec-93d9-0242ac110002 UniProtKB:P08243 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Asparagine synthetase [glutamine-hydrolyzing]) DrugCentral uuid:334dacc6-7972-11ec-93d9-0242ac110002 UniProtKB:P00966 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Argininosuccinate synthase) DrugCentral uuid:334dd2f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q03154 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aminoacylase-1) DrugCentral uuid:334df8fc-7972-11ec-93d9-0242ac110002 UniProtKB:P00505 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate aminotransferase, mitochondrial) DrugCentral uuid:334e1eb8-7972-11ec-93d9-0242ac110002 UniProtKB:P14868 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate--tRNA ligase, cytoplasmic) DrugCentral uuid:334e435c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12797 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartyl/asparaginyl beta-hydroxylase) DrugCentral uuid:334e68dc-7972-11ec-93d9-0242ac110002 UniProtKB:P43003 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:334e926c-7972-11ec-93d9-0242ac110002 UniProtKB:P43004 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:334ebb70-7972-11ec-93d9-0242ac110002 UniProtKB:P43005 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:334ee474-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UJS0 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Calcium-binding mitochondrial carrier protein Aralar2) DrugCentral uuid:334f207e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:334f207e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:334f207e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:334f207e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:334f207e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:334f207e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:334f207e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:334f91e4-7972-11ec-93d9-0242ac110002 UniProtKB:O35921 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:334fbe44-7972-11ec-93d9-0242ac110002 UniProtKB:O59010 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Glutamate transporter homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:334fe7ac-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.757']} DrugCentral uuid:3350109c-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.187']} DrugCentral uuid:33503aa4-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:335063bc-7972-11ec-93d9-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:33508cf2-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.287']} DrugCentral uuid:3350b60a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.338']} DrugCentral uuid:3350df90-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:335108bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide is inhibitor of Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:335131de-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:33515ad8-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.684']} DrugCentral uuid:335186de-7972-11ec-93d9-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3351b03c-7972-11ec-93d9-0242ac110002 UniProtKB:O35435 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3351d95e-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:33520262-7972-11ec-93d9-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:33522c06-7972-11ec-93d9-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3352551e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:33527e40-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leuprorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:3352a758-7972-11ec-93d9-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:1559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leuprorelin targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3352d0ac-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:3352f9c4-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:335322be-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:335359f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:335359f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:335359f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:335359f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:3353a716-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N587 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Ion channel (Acetylcholine receptor subunit alpha-type unc-63) DrugCentral uuid:3353cbd8-7972-11ec-93d9-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3353f5a4-7972-11ec-93d9-0242ac110002 UniProtKB:O96760 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole is agonist of Ion channel (Nicotinic acetylcholine receptor alpha subunit) DrugCentral uuid:33541a66-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.568']} DrugCentral uuid:33544400-7972-11ec-93d9-0242ac110002 UniProtKB:P09487 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:33546d0e-7972-11ec-93d9-0242ac110002 UniProtKB:P09923 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Intestinal-type alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:33549680-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:3354bfac-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3354e8ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:335511b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:33553f04-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33559990-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33566032-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:335684c2-7972-11ec-93d9-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:3356a98e-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:3356ce64-7972-11ec-93d9-0242ac110002 UniProtKB:Q02563 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam is inhibitor of Unclassified (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3356f8c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L0J3 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam is modulator of Transporter (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:33572206-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:335746dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.279']} DrugCentral uuid:33576ffe-7972-11ec-93d9-0242ac110002 UniProtKB:O95665 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is agonist of GPCR (Neurotensin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:33579af6-7972-11ec-93d9-0242ac110002 UniProtKB:Q63384 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine targets GPCR (Neurotensin receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3357c40e-7972-11ec-93d9-0242ac110002 UniProtKB:P70310 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is agonist of GPCR (Neurotensin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3357ed44-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocetirizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:33581760-7972-11ec-93d9-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:335840c8-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.541']} DrugCentral uuid:335869a4-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:33589294-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:3358bb8e-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.646']} DrugCentral uuid:3358e7f8-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa is agonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:33590e18-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa is agonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:335932d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.04']} DrugCentral uuid:33595bde-7972-11ec-93d9-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:33598596-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:3359b282-7972-11ec-93d9-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:3359b282-7972-11ec-93d9-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:3359e5b8-7972-11ec-93d9-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:3359e5b8-7972-11ec-93d9-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:335a157e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y256 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:335a3e64-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadyl acetate is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:335a631c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadyl acetate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:335a8cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.225']} DrugCentral uuid:335ab8c6-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:335ae242-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:335b072c-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['12.796']} DrugCentral uuid:335b3030-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.91']} DrugCentral uuid:335b5a1a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:335b833c-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.339']} DrugCentral uuid:335bac72-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:335bd5ee-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:335bfefc-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:335c2904-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:335c51d6-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:335c7bd4-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:335ca4e2-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:335ccdfa-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:335cf712-7972-11ec-93d9-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:335d20ca-7972-11ec-93d9-0242ac110002 UniProtKB:O55242 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:335d6206-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:335d6206-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:335d6206-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:335d6206-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:335d6206-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:335d6206-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:335d6206-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:335deae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:335deae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:335deae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:335deae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:335deae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:335deae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:335deae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:335e696c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:335e696c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:335e696c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:335e696c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:335ebf20-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:335ebf20-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:335ebf20-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:335f011a-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:335f2a14-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosalbutamol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:335f5322-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) DrugCentral uuid:335f77d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) DrugCentral uuid:335f9cf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q15842 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Ion channel (ATP-sensitive inward rectifier potassium channel 8) DrugCentral uuid:335fc1d6-7972-11ec-93d9-0242ac110002 UniProtKB:P63316 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan is opener of Cytosolic other (Troponin C, slow skeletal and cardiac muscles) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.155']} DrugCentral uuid:335feae4-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:33601406-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:33603e2c-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:336067e4-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:336090e8-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:3360baa0-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3360f312-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3360f312-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3360f312-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3360f312-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3360f312-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:336155be-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:336155be-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:336155be-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:33619eca-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:33619eca-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:33619eca-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:3361e10a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:33620bf8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:336230e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:336259fa-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:33628330-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3362acd4-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.296']} DrugCentral uuid:3362d5e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:3362faa4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.559']} DrugCentral uuid:33632baa-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:33632baa-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:33632baa-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:33637484-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:33637484-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:33637484-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3363b5ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3363e02c-7972-11ec-93d9-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:33640944-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:33643252-7972-11ec-93d9-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:33646380-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:33646380-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:33646380-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3364a4d0-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 limaprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) DrugCentral uuid:3364c988-7972-11ec-93d9-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:1582 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lincomycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:3364ee40-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:3365179e-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:336541a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q75NA5 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:33656aa0-7972-11ec-93d9-0242ac110002 UniProtKB:P24046 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:33659ce6-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:33659ce6-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:33659ce6-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3365e598-7972-11ec-93d9-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:3365e598-7972-11ec-93d9-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:3365e598-7972-11ec-93d9-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:33662850-7972-11ec-93d9-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:33662850-7972-11ec-93d9-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:33662850-7972-11ec-93d9-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:336669fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:336669fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:336669fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3366b32e-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:3366b32e-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:3366b32e-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:3366f4ce-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:33671dbe-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:336746c2-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:33677106-7972-11ec-93d9-0242ac110002 UniProtKB:P31040 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:33679a0a-7972-11ec-93d9-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine is agonist of Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.24']} DrugCentral uuid:3367c32c-7972-11ec-93d9-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine is agonist of Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:3367ec26-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3368158e-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:33683e7e-7972-11ec-93d9-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:33686868-7972-11ec-93d9-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:33689144-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3368f3aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336a1578-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:336af52e-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1587 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisinopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:336b1ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1587 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisinopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:336b498e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.491']} DrugCentral uuid:336b7292-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:336b9b8c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:336bc4f4-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:336bedda-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.936']} DrugCentral uuid:336c16de-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:336c3fec-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.061']} DrugCentral uuid:336c6968-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:336c9280-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.259']} DrugCentral uuid:336cbb8e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:336ce488-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.625']} DrugCentral uuid:336d11ce-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:336d3de8-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:336d6764-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:336d919e-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:336dba8e-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:336de388-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:336e0c8c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.203']} DrugCentral uuid:336e35fe-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:336e609c-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:336e89a0-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.037']} DrugCentral uuid:336eb29a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.78']} DrugCentral uuid:336edd92-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:336f06a0-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.338']} DrugCentral uuid:336f2f86-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:336f58d0-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:336f81b6-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.33']} DrugCentral uuid:336faaa6-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:336fd3aa-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:336ffd30-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.489']} DrugCentral uuid:33702616-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:33704f24-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:33707828-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.268']} DrugCentral uuid:3370a262-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:3370cb48-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3370f44c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:33711d32-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.444']} DrugCentral uuid:33714686-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:33716f80-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.481']} DrugCentral uuid:33719974-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.886']} DrugCentral uuid:3371c25a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.468']} DrugCentral uuid:3371eba4-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:33721494-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:33723dc0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:33726804-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:33729144-7972-11ec-93d9-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:3372c1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3372c1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3372c1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:33730b10-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:33730b10-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:33730b10-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:33734c2e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:3373751e-7972-11ec-93d9-0242ac110002 UniProtKB:P43700 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3373a246-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:3373a246-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:3373d2c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomerizine targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:3373fbba-7972-11ec-93d9-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:1597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonazolac targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:337424dc-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:33745056-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:337479aa-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:3374a2ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) DrugCentral uuid:3374c766-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:3374f164-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.932']} DrugCentral uuid:33751a68-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:33754466-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.343']} DrugCentral uuid:33756d6a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:337596d2-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.519']} DrugCentral uuid:3375bfd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3375e8bc-7972-11ec-93d9-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) DrugCentral uuid:33760d74-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:337638b2-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.599']} DrugCentral uuid:337661ac-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:33769244-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:33769244-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:33769244-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:3376cc5a-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:3376f55e-7972-11ec-93d9-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.345']} DrugCentral uuid:33771e62-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) DrugCentral uuid:3377431a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) DrugCentral uuid:33776868-7972-11ec-93d9-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) DrugCentral uuid:33778d16-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3377b61a-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:3377def6-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:33780912-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:33783220-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:33785b24-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:33788496-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3378adc2-7972-11ec-93d9-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3378de64-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3378de64-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3378de64-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:33792112-7972-11ec-93d9-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:33794a0c-7972-11ec-93d9-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:33797446-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:33799d4a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:3379c75c-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:3379ec32-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:337a1540-7972-11ec-93d9-0242ac110002 UniProtKB:Q80W54 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Enzyme (CAAX prenyl protease 1 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:337a3e4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:337a6798-7972-11ec-93d9-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.59']} DrugCentral uuid:337a90a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.54']} DrugCentral uuid:337ac148-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:337ac148-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:337ac148-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:337b034c-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:337b034c-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:337b034c-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:337b451e-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:337b451e-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:337b451e-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:337b866e-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:337b866e-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:337b866e-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:337bc0d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:337bfc52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:337bfc52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:337bfc52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:337bfc52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:337bfc52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:337bfc52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:337bfc52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:337c6174-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:337c8a6e-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:337cb39a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:337cdd84-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:337d069c-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:337d2f82-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:337d5886-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:337d837e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:337dac6e-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:337dd6bc-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:337e001a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2J7 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Transporter (Sodium-dependent neutral amino acid transporter B(0)AT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:337e291e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:337e5222-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:337e82ec-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:337e82ec-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:337e82ec-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:337ec4a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:337ee94e-7972-11ec-93d9-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:337f0e06-7972-11ec-93d9-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:337f32c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:337f58b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:337f7d64-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.498']} DrugCentral uuid:337fa686-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:337fcf94-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:337ff8f2-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:338021e2-7972-11ec-93d9-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:33804bd6-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:33807598-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:33809e7e-7972-11ec-93d9-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:3380c76e-7972-11ec-93d9-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:3380f07c-7972-11ec-93d9-0242ac110002 UniProtKB:P34976 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:33811aca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WV26 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:338147a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:338147a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:33818802-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:33818802-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:33818802-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:33818802-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:3381d9c4-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3381d9c4-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:33821696-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:33821696-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:33821696-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:33825bce-7972-11ec-93d9-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:33825bce-7972-11ec-93d9-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:338290e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCN6 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Unclassified (Platelet glycoprotein VI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:3382b9e8-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loteprednol etabonate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3382e076-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.061']} DrugCentral uuid:338309ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:338332ba-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.807']} DrugCentral uuid:33835bd2-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:33838530-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.67']} DrugCentral uuid:3383aefc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3383d7ec-7972-11ec-93d9-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Hydroxycarboxylic acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:338400dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:33842a94-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3384538e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:33847c88-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:3384a596-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.697']} DrugCentral uuid:3384cf76-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3384f884-7972-11ec-93d9-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:33852160-7972-11ec-93d9-0242ac110002 UniProtKB:Q01237 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:33854a78-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:338573e0-7972-11ec-93d9-0242ac110002 UniProtKB:P20701 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Adhesion (Leukocyte adhesion glycoprotein LFA-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:33859cc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q95214 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Acyl-CoA:cholesterol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:3385c5ac-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.268']} DrugCentral uuid:3385ef78-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:33861886-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:3386418a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.244']} DrugCentral uuid:33866a52-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:338694f0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:3386bf02-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3386e810-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3387111e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:33873a9a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:338763b2-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:33878cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:3387b696-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3387e058-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.682']} DrugCentral uuid:3388093e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.297']} DrugCentral uuid:33883238-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:33885b14-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.376']} DrugCentral uuid:33888580-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:3388ae70-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.087']} DrugCentral uuid:3388d76a-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.829']} DrugCentral uuid:33890208-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.411']} DrugCentral uuid:33892b0c-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:33895410-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:33897d32-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3389a6cc-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:3389cfc6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.276']} DrugCentral uuid:3389f8d4-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:338a21ce-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.854']} DrugCentral uuid:338a4d66-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:338a7804-7972-11ec-93d9-0242ac110002 UniProtKB:Q5JUK3 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:338aa0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:338ac9d0-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:338af338-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:338b1c5a-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:338b455e-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:338b6ef8-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:338b9fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:338b9fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:338b9fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:338be22a-7972-11ec-93d9-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:1614 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxiglumide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:338c0c32-7972-11ec-93d9-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:1614 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxiglumide is antagonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:338c357c-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:338c5e80-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:338c8770-7972-11ec-93d9-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lucanthone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:338cb09c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumefantrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:338cd98c-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:338d0290-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:338d2b94-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:338d5524-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:338d7e28-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:338da72c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.979']} DrugCentral uuid:338dcffe-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.856']} DrugCentral uuid:338dfaba-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.12']} DrugCentral uuid:338e23c8-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:338e4ccc-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:338e75d0-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:338e9f56-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:338ec850-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:338ef28a-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:338f1c24-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.81']} DrugCentral uuid:338f4546-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:338f6ee0-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:338f98c0-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:338fc35e-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:338fec76-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:33901584-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:33903eb0-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3390687c-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:33909194-7972-11ec-93d9-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3390baa2-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3390ebee-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3390ebee-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3390ebee-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:33912d52-7972-11ec-93d9-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysine targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:33915660-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:33917f50-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3391aa02-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3391d2f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:3391fbe2-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:339225a4-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:33924a52-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:3392736a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:33929c6e-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3392c5ea-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3392eeda-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:339317d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:339340ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:33936b12-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:339394de-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3393bdd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:3393e6c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:3394106c-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:33943970-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:33946292-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:33948bb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:3394b508-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:3394df56-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:33950864-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:33953302-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:33955c2e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:33958546-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3395ae54-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3395d7d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:339600d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:339629d8-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:339652be-7972-11ec-93d9-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:1626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 malathion targets GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.538']} DrugCentral uuid:33967c3a-7972-11ec-93d9-0242ac110002 UniProtKB:A2PZ98 biolink:molecularly_interacts_with DrugCentral:1626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 malathion is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:3396a0d4-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3396cda2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:3396cda2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:3396fcb4-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.308']} DrugCentral uuid:33972658-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:33974f66-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.165']} DrugCentral uuid:3397786a-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.364']} DrugCentral uuid:3397a2f4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:3397cbf8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.27']} DrugCentral uuid:3397f4e8-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:33981df6-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:3398475e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:3398708a-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:3398998e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.854']} DrugCentral uuid:3398c288-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.876']} DrugCentral uuid:3398ed94-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.298']} DrugCentral uuid:339918c8-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.367']} DrugCentral uuid:339941cc-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.777']} DrugCentral uuid:33996ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.406']} DrugCentral uuid:33999492-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:3399bd96-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:3399e69a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:339a0f80-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:339a38e8-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.939']} DrugCentral uuid:339a61d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:339a8aa0-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.355']} DrugCentral uuid:339ab4e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:339adf46-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:339b0854-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:339b2cf8-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:339b569c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:339b8022-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:339baa16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:339bd338-7972-11ec-93d9-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc is antagonist of GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:339bfcaa-7972-11ec-93d9-0242ac110002 UniProtKB:P51682 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:339c25b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:339c4eb2-7972-11ec-93d9-0242ac110002 UniProtKB:P61813 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:339c77c0-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:339ca344-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:339ccc5c-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:339cf54c-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:339d1ebe-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:339d47cc-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:339d70b2-7972-11ec-93d9-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:339d99c0-7972-11ec-93d9-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:339dc314-7972-11ec-93d9-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:339dec04-7972-11ec-93d9-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:339e14f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:339e3e02-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:339e67ba-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:339e90b4-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:339eb9b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:339ee2b2-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:339f0c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:339f3564-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BEG3 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:339f5e4a-7972-11ec-93d9-0242ac110002 UniProtKB:P48999 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:339f8b2c-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:339f8b2c-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:339fc1c8-7972-11ec-93d9-0242ac110002 UniProtKB:O15296 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase, type II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:339feab8-7972-11ec-93d9-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:33a01394-7972-11ec-93d9-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:33a03e8c-7972-11ec-93d9-0242ac110002 UniProtKB:K4CF70 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Fatty acid hydroperoxide lyase, chloroplastic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:33a067cc-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:33a090c6-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:1638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maxacalcitol targets Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:33a0baf6-7972-11ec-93d9-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:1638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maxacalcitol is agonist of Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:33a0e486-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:33a10e0c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:33a1372e-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:33a1600a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:33a18972-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:33a1b26c-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:33a1db70-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:33a2056e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:33a22e9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:33a25776-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:33a28066-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:33a2a9ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BJF5 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Calmodulin-domain protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:33a2da84-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a2da84-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a2da84-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a32afc-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a32afc-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a32afc-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a32afc-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a32afc-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a32afc-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a32afc-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:33a3900a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.119']} DrugCentral uuid:33a3b8fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (Histamine H4 receptor) DrugCentral uuid:33a3dee8-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:33a409fe-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:33a4330c-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.161']} DrugCentral uuid:33a45c06-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:33a48956-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:33a48956-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:33a4c218-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.602']} DrugCentral uuid:33a4c218-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.602']} DrugCentral uuid:33a4fb16-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is negative allosteric modulator of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:33a4fb16-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is negative allosteric modulator of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:33a53482-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:33a53482-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:33a56d58-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:33a56d58-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:33a5afe8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:33a5afe8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:33a5afe8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:33a5afe8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:33a5fd0e-7972-11ec-93d9-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:33a626ee-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:33a6507e-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:33a67978-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:33a6a290-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:1648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecillinam is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.035']} DrugCentral uuid:33a6cb9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:33a6f524-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:33a719e6-7972-11ec-93d9-0242ac110002 UniProtKB:O35627 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is agonist of Nuclear hormone receptor (Constitutive androstane receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:33a74326-7972-11ec-93d9-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:33a76cc0-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:33a796dc-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:33a7bfd6-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:33a7e8d0-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:33a811de-7972-11ec-93d9-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:33a83b8c-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:33a8649a-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:33a88d80-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:33a8b698-7972-11ec-93d9-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:33a8e014-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:33a90936-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.503']} DrugCentral uuid:33a93226-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:33a95c7e-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:33a98884-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:33a9b5c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:33a9b5c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33aa24e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:33ab0d30-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:33ab0d30-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:33ab0d30-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:33ab59a2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:33ab59a2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:33ab59a2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:33aba290-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:33aba290-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:33aba290-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:33abec00-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:33abec00-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:33abec00-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:33ac2e54-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxalol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'pA2', 'has_quantitative_value': ['7.82']} DrugCentral uuid:33ac576c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxalol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'pA2', 'has_quantitative_value': ['6.08']} DrugCentral uuid:33ac80f2-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.561']} DrugCentral uuid:33acaa1e-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:33acd336-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:33acfc3a-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:33ad25f2-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.59']} DrugCentral uuid:33ad4eec-7972-11ec-93d9-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:33ad77e6-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:33ada14e-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:33adcaca-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:33adf3e2-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:33ae1d04-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:33ae4658-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.032']} DrugCentral uuid:33ae6f66-7972-11ec-93d9-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:33ae9d7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:33ae9d7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:33aed398-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1662 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medrysone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:33aef968-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:33af2280-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:33af4b70-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:33af74e2-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:33af9de6-7972-11ec-93d9-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:33afc7ee-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:33aff110-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:33b01a82-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:33b0437c-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:33b06c94-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:33b0957a-7972-11ec-93d9-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:33b0bffa-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:33b0e8d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:33b111d0-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:33b13ad4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:33b16450-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:33b18912-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:33b1b20c-7972-11ec-93d9-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:33b1d6ce-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:33b20036-7972-11ec-93d9-0242ac110002 UniProtKB:P90584 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Unclassified (Protein kinase Pfmrk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:33b22930-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:33b24dfc-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.057']} DrugCentral uuid:33b27732-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:33b29eb0-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:33b2c7b4-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:33b2f0c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.842']} DrugCentral uuid:33b31a48-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meglutol targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:33b34356-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:33b36c8c-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.56']} DrugCentral uuid:33b395a4-7972-11ec-93d9-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:33b3bf98-7972-11ec-93d9-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:33b3e96e-7972-11ec-93d9-0242ac110002 UniProtKB:P35398 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Nuclear hormone receptor (Nuclear receptor ROR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:33b41272-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:33b43b6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:33b466fa-7972-11ec-93d9-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:33b49026-7972-11ec-93d9-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:33b4c0d2-7972-11ec-93d9-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:33b4c0d2-7972-11ec-93d9-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:33b4c0d2-7972-11ec-93d9-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:33b50272-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:33b52b76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:33b554ac-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:33b57d92-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:33b5a6fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:33b5d01c-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:33b5f90c-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:33b621fc-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:33b64e02-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:33b6771a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:33b69bc8-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:33b6c54e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.717']} DrugCentral uuid:33b6ee66-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:33b7177e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:33b74096-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.063']} DrugCentral uuid:33b769e0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:33b792e4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:33b7bbf2-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.357']} DrugCentral uuid:33b7e618-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.469']} DrugCentral uuid:33b810f2-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:33b83596-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:33b85eae-7972-11ec-93d9-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:1678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melphalan targets Transporter (L-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:33b887c6-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Ion channel (5-hydroxytryptamine receptor 3A) DrugCentral uuid:33b8ad0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:33b8d1f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q05586 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:33b8fb02-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:33b923de-7972-11ec-93d9-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:33b95142-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:33b95142-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:33b98a72-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:33b98a72-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:33b9c014-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:33b9eaa8-7972-11ec-93d9-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:33ba1500-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:33ba3e0e-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:33ba671c-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:33ba908e-7972-11ec-93d9-0242ac110002 UniProtKB:P30305 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (M-phase inducer phosphatase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:33bab9a6-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:33bae296-7972-11ec-93d9-0242ac110002 UniProtKB:P30307 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity phosphatase Cdc25C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:33bb0bea-7972-11ec-93d9-0242ac110002 UniProtKB:P15374 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Ubiquitin carboxyl-terminal hydrolase isozyme L3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:33bb34ee-7972-11ec-93d9-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33bb5dd4-7972-11ec-93d9-0242ac110002 UniProtKB:Q64346 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity protein phosphatase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:33bb86ce-7972-11ec-93d9-0242ac110002 UniProtKB:P28563 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:33bbb284-7972-11ec-93d9-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (M-phase inducer phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:33bbdb92-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:33bc0482-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione sodium bisulfite targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:33bc2d9a-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1685 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menatetrenone targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:33bc56ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:33bc8006-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.119']} DrugCentral uuid:33bca90a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:33bcd20e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:33bcfb8a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.485']} DrugCentral uuid:33bd24ac-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:33bd4dba-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.069']} DrugCentral uuid:33bd76c8-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.742']} DrugCentral uuid:33bda116-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.167']} DrugCentral uuid:33bdca10-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.504']} DrugCentral uuid:33bdf314-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:33be1c72-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:33be4580-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:33be6e8e-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:33be979c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:33bec104-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:33beea1c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:33bf13a2-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.411']} DrugCentral uuid:33bf3c9c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:33bf68c0-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:33bf9200-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UDY8 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Enzyme (Mucosa-associated lymphoid tissue lymphoma translocation protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:33bfbbea-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:33bfe098-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:33c00a1e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:33c03462-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:33c05d70-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:33c086e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:33c0afc8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:33c0d46c-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.625']} DrugCentral uuid:33c0fd98-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:33c12354-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:33c14cbc-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:33c175b6-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:33c19ece-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:33c1d3bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:33c1d3bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:33c1d3bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:33c1d3bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:33c22c54-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:33c22c54-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:33c22c54-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:33c22c54-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:33c279de-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:33c2a2ce-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephentermine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c2e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:33c37b68-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33c37b68-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33c37b68-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33c3b5ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:33c3da86-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:33c3ff48-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:33c4240a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:33c4493a-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:33c46f28-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:33c493ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:33c4b8c0-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprednisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:33c4dfda-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.821']} DrugCentral uuid:33c513e2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:33c513e2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:33c513e2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:33c55578-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:33c55578-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:33c55578-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:33c59786-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:33c59786-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:33c59786-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:33c5d8e0-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33c5d8e0-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33c5d8e0-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33c612e2-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meproscillarin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:33c6389e-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:33c66166-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:33c68a56-7972-11ec-93d9-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:33c6b440-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:33c6dd30-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.06']} DrugCentral uuid:33c705f8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.237']} DrugCentral uuid:33c72efc-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:33c7586e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:33c7817c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.276']} DrugCentral uuid:33c7aa76-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.955']} DrugCentral uuid:33c7d37a-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:33c7fcf6-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:33c825dc-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:33c84eea-7972-11ec-93d9-0242ac110002 UniProtKB:Q389T8 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:33c87942-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.789']} DrugCentral uuid:33c8a2c8-7972-11ec-93d9-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:33c8c76c-7972-11ec-93d9-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:33c8ec10-7972-11ec-93d9-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Purine nucleoside phosphorylase) DrugCentral uuid:33c9110e-7972-11ec-93d9-0242ac110002 UniProtKB:Q06203 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine is inhibitor of Enzyme (Amidophosphoribosyltransferase) DrugCentral uuid:33c935c6-7972-11ec-93d9-0242ac110002 UniProtKB:P51580 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Thiopurine S-methyltransferase) DrugCentral uuid:33c95bb4-7972-11ec-93d9-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.1']} DrugCentral uuid:33c984c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:33c9a97a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:33c9cea0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:33c9f344-7972-11ec-93d9-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:33ca17f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:33ca3ca0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem is inhibitor of Enzyme (D-alanyl-D-alanine carboxypeptidase DacB) DrugCentral uuid:33ca6504-7972-11ec-93d9-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:33ca8dd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9K2N0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Unclassified (Beta-lactamase class B VIM-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:33cab6e4-7972-11ec-93d9-0242ac110002 UniProtKB:C7C422 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Beta-lactamase NDM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.96']} DrugCentral uuid:33cadfe8-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XEC0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:33cb0982-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:33cb3290-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:33cb5770-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:33cb7cb4-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:33cba1e4-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:33cbcaf2-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:33cbf400-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:33cc1d04-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WU19 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Hydroxyacid oxidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:33cc4734-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:33cc704c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.724']} DrugCentral uuid:33cc996e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:33ccc2d6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:33ccebf8-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.125']} DrugCentral uuid:33cd1506-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.804']} DrugCentral uuid:33cd3e14-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:33cd6786-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:33cd9080-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.744']} DrugCentral uuid:33cdb97a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:33cde274-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:33ce0e7a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:33ce3954-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:33ce6258-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:33ce8c56-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.041']} DrugCentral uuid:33ceb5e6-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.647']} DrugCentral uuid:33cedef4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:33cf0802-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:33cf3188-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.282']} DrugCentral uuid:33cf5be0-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:33cf84ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.958']} DrugCentral uuid:33cfae1a-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orciprenaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:33cfd962-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orciprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:33d002d4-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metaraminol is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:33d0278c-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:33d050a4-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:33d07a34-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:33d0a342-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:33d0cc64-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.504']} DrugCentral uuid:33d0f568-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:33d11ec6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:33d147de-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:33d170ec-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:33d19a90-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:33d1c4e8-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:33d1edd8-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:33d216f0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.124']} DrugCentral uuid:33d2406c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.583']} DrugCentral uuid:33d26970-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:33d29378-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:33d2bc86-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:33d2e602-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:33d30f1a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:33d3383c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:33d36136-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:33d38c2e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:33d3b53c-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.872']} DrugCentral uuid:33d3de40-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:33d40762-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:33d430f2-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:33d45a0a-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.867']} DrugCentral uuid:33d482fa-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:33d4ac76-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:33d4d57a-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:33d4fe7e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:33d52796-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:33d553a6-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:33d57d4a-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:33d5b1ca-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33d5b1ca-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33d5b1ca-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33d5b1ca-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33d60710-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:33d60710-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:33d60710-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:33d64946-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y478 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Kinase (5'-AMP-activated protein kinase subunit beta-1) DrugCentral uuid:33d66dea-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:33d6973e-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.697']} DrugCentral uuid:33d6c01a-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.401']} DrugCentral uuid:33d6e90a-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['2.499']} DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33d7d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:33da009a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:33da2ab6-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:33da53ec-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:33da78ae-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:33daa1d0-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:33dacd0e-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:33daf612-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:33db1f0c-7972-11ec-93d9-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:33db4824-7972-11ec-93d9-0242ac110002 UniProtKB:P43351 biolink:molecularly_interacts_with DrugCentral:1727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metacycline targets Nuclear other (DNA repair protein RAD52 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:33db7196-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.78']} DrugCentral uuid:33db9aae-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:33dbc4de-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:33dbedc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:33dc12d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:33dc3798-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:33dc6c2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:33dc6c2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:33dc6c2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:33dc6c2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:33dcbc36-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylmethadol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:33dce544-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylmethadol is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:33dd09e8-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.383']} DrugCentral uuid:33dd3314-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:33dd5c90-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.133']} DrugCentral uuid:33dd85bc-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:33ddaeca-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:33ddd85a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:33de0172-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:33de2a94-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.611']} DrugCentral uuid:33de53ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:33de7ef4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:33dea7f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:33ded0e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.88']} DrugCentral uuid:33def9d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:33df32a4-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:33df32a4-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:33df32a4-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:33df32a4-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:33df32a4-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:33df815a-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:33dfaaea-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:33dfd3f8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:33dffd24-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:33e026d2-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:33e05152-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.409']} DrugCentral uuid:33e07a74-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.843']} DrugCentral uuid:33e0a38c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:33e0cca4-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:33e0f760-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.939']} DrugCentral uuid:33e12082-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.228']} DrugCentral uuid:33e14990-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:33e172a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:33e19c1a-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:33e1ccda-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:33e1ccda-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:33e1ccda-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:33e21780-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:33e21780-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:33e21780-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:33e26096-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:33e26096-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:33e26096-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:33e2a970-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:33e2a970-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:33e2a970-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:33e2f380-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:33e2f380-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:33e2f380-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:33e33c64-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:33e33c64-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:33e33c64-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:33e385d4-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:33e385d4-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:33e385d4-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:33e3cae4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:33e3cae4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:33e4093c-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:33e4093c-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:33e4093c-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:33e45338-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:33e45338-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:33e45338-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e4cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33e59158-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:33e5ba98-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:33e5e7ca-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:33e61150-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:33e63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:33e66402-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:33e68d06-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:33e6b6b4-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:33e6e0bc-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:33e70a4c-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:33e73378-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:33e75cae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:33e785d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:33e7b1cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:33e7db02-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:33e8042e-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:33e82d46-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:33e856e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:33e8800c-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:33e8a92e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:33e8d2dc-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:33e8fc08-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:33e92534-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:33e94e60-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:33e97ad4-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:33e9a41e-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:33e9cd2c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:33e9f64e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:33ea1fd4-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33ea72c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:33eb2596-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:33eb2596-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:33eb5ce6-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:33eb85fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:33ebaf0c-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:33ebd838-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methdilazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:33ebfd72-7972-11ec-93d9-0242ac110002 UniProtKB:P07944 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin targets Enzyme (Beta-lactam-inducible penicillin-binding protein) DrugCentral uuid:33ec223e-7972-11ec-93d9-0242ac110002 UniProtKB:P18843 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin targets Enzyme (NH(3)-dependent NAD(+) synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:33ec5aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:33ec5aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:33ec5aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:33ec5aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:33ec5aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:33ecab50-7972-11ec-93d9-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole is inhibitor of Enzyme (Thyroid peroxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:33ecd472-7972-11ec-93d9-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:33ecfd76-7972-11ec-93d9-0242ac110002 UniProtKB:P22079 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:33ed271a-7972-11ec-93d9-0242ac110002 UniProtKB:P15101 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Dopamine beta-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:33ed5046-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1747 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methocarbamol is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:33ed795e-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:33eda5d2-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33eda5d2-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33eda5d2-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:33ee3e3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:33ee3e3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:33eea1b2-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:33eeebea-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:33ef3550-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:33ef7e98-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:33efac92-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:33efdbf4-7972-11ec-93d9-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:33f004d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:33f033f6-7972-11ec-93d9-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:33f05de0-7972-11ec-93d9-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:33f08b58-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:33f0b8d0-7972-11ec-93d9-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:33f0e6c0-7972-11ec-93d9-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:33f11438-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:33f141ce-7972-11ec-93d9-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:33f1714e-7972-11ec-93d9-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.14']} DrugCentral uuid:33f1a01a-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:33f1cda6-7972-11ec-93d9-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:33f1fbaa-7972-11ec-93d9-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.89']} DrugCentral uuid:33f22936-7972-11ec-93d9-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:33f256c2-7972-11ec-93d9-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:33f28444-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.68']} DrugCentral uuid:33f2b25c-7972-11ec-93d9-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:33f2dffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:33f30eaa-7972-11ec-93d9-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:33f33d9e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WNX1 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.08']} DrugCentral uuid:33f36b02-7972-11ec-93d9-0242ac110002 UniProtKB:Q81R22 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.91']} DrugCentral uuid:33f3987a-7972-11ec-93d9-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:33f3c5e8-7972-11ec-93d9-0242ac110002 UniProtKB:P00380 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:33f3f3f6-7972-11ec-93d9-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:33f42182-7972-11ec-93d9-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:33f44f22-7972-11ec-93d9-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:33f47df8-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:33f4abac-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomepromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.237']} DrugCentral uuid:33f4dabe-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomepromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:33f509e4-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:33f53b12-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:33f568d0-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:33f59670-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:33f5cd0c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:33f5cd0c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:33f5cd0c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:33f61604-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is agonist of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f67e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:33f75d98-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:33f78ba6-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:33f7b95a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:33f7e6f0-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.01']} DrugCentral uuid:33f81512-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:33f84294-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:33f87890-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:33f87890-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:33f87890-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:33f8bb16-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylclothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:33f8e406-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metildigoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:33f90cce-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa is agonist of GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:33f936d6-7972-11ec-93d9-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:33f96020-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.282']} DrugCentral uuid:33f98dac-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.286']} DrugCentral uuid:33f9bb38-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.672']} DrugCentral uuid:33f9e946-7972-11ec-93d9-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:33fa16b4-7972-11ec-93d9-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:33fa4418-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:33fa717c-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:33faa0f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Thioredoxin reductase 1, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:33face74-7972-11ec-93d9-0242ac110002 UniProtKB:O15770 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Glutathione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:33fafbec-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:33fb2a5e-7972-11ec-93d9-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:33fb57c2-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:33fb85f8-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:33fbb398-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:33fbe200-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.225']} DrugCentral uuid:33fc0fb4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.633']} DrugCentral uuid:33fc3d68-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:33fc6d74-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is partial agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:33fc9b6e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:33fcc90e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.928']} DrugCentral uuid:33fcf744-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.678']} DrugCentral uuid:33fd24ee-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:33fd52a2-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:33fd802e-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:33fdaec8-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:33fddc54-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.033']} DrugCentral uuid:33fe0a08-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:33fe3938-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:33fe6728-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:33fe94dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:33fec290-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:33fef080-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.93']} DrugCentral uuid:33ff200a-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:33ff4db4-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:33ff7bf4-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:33ffa9a8-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.58']} DrugCentral uuid:33ffd89c-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:34000718-7972-11ec-93d9-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:340034c2-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:34006262-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:34009002-7972-11ec-93d9-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3400bdde-7972-11ec-93d9-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.97']} DrugCentral uuid:3400eb60-7972-11ec-93d9-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:340125a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:340125a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:340125a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:340125a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:34018124-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:34018124-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:3401bc70-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3401eb82-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:34021918-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:340246ae-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:34027548-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3402a2e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3402d07e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.252']} DrugCentral uuid:3402fe1e-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:34032c86-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:34035b20-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.615']} DrugCentral uuid:340388b6-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:3403b7b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3403e540-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:340412cc-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:34044026-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone targets Cytosolic other (Annexin A1) DrugCentral uuid:3404697a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:3404971a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3404c492-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3404ee18-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1771 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone succinate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:34051f78-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:34051f78-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:34051f78-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:34055ff6-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.326']} DrugCentral uuid:34058ec2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3405bd98-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.214']} DrugCentral uuid:3405eb1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:340618a6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:340646a0-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:34067440-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3406a1e0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.663']} DrugCentral uuid:3406d048-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:3406fdde-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:34072b7e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:34075a40-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.213']} DrugCentral uuid:340787cc-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.334']} DrugCentral uuid:3407b648-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3407e3f2-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:340811f6-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.054']} DrugCentral uuid:34083f96-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:34086d40-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:34089b76-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3408c948-7972-11ec-93d9-0242ac110002 UniProtKB:Q07820 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Induced myeloid leukemia cell differentiation protein Mcl-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:3408f7a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:34092532-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:340953e0-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:34098176-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3409af0c-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3409dd1a-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:340a0ab0-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:340a3846-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:340a6f28-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:340a6f28-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:340a6f28-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:340ab802-7972-11ec-93d9-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:340ae58e-7972-11ec-93d9-0242ac110002 UniProtKB:P35364 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:340b150e-7972-11ec-93d9-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:340b42ae-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:340b7044-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.45']} DrugCentral uuid:340b9e48-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:340bcc10-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:340bfac8-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metiazinic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:340c29b2-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metipranolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:340c532e-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metipranolol is antagonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:340c7c0a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene is antagonist of GPCR (5-hydroxytryptamine receptor 2C) DrugCentral uuid:340ca4dc-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:340ccd9a-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:340cfd56-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metochalcone targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:340d2ac4-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:340d585a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:340d865e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:340db3ea-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:340de176-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.397']} DrugCentral uuid:340e0fac-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:340e3d38-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:340e6b46-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:340e93f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.509']} DrugCentral uuid:340ec488-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:340ef232-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:340f1fdc-7972-11ec-93d9-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:340f4da4-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:340f7bb2-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:340fa90c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:340fd6a2-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:34100500-7972-11ec-93d9-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3410328c-7972-11ec-93d9-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:34106018-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3410943e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3410943e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3410e04c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3410e04c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3410e04c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3410e04c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3410e04c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3411514e-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3411514e-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3411514e-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3411514e-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3411affe-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3411affe-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3411affe-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:34120346-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:34120346-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:34120346-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:341255c6-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:341255c6-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:341255c6-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:3412a800-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3412a800-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3412e32e-7972-11ec-93d9-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3413111e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone targets Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.45']} DrugCentral uuid:34133ed2-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:341368a8-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:34139710-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:3413c4ec-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:3413f2d2-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:34142072-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:34144ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34147c84-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:3414aa2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.79']} DrugCentral uuid:3414d85a-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.83']} DrugCentral uuid:34150e60-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34150e60-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34150e60-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3415571c-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:3415855c-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:3415b2f2-7972-11ec-93d9-0242ac110002 UniProtKB:C4LW95 biolink:molecularly_interacts_with DrugCentral:1790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metronidazole targets Enzyme (Thioredoxin reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3415e13c-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:341610bc-7972-11ec-93d9-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:34163e52-7972-11ec-93d9-0242ac110002 UniProtKB:P15150 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:34166be8-7972-11ec-93d9-0242ac110002 UniProtKB:P15393 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:341699f6-7972-11ec-93d9-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.84']} DrugCentral uuid:3416c78c-7972-11ec-93d9-0242ac110002 UniProtKB:P07101 biolink:molecularly_interacts_with DrugCentral:1792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metirosine is inhibitor of Enzyme (Tyrosine 3-monooxygenase) DrugCentral uuid:3416f05e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:34171dcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:3417473e-7972-11ec-93d9-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:34177146-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:34179a18-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:3417c2f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3417f580-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:34182348-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:341850f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:34187ef6-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:3418ac8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:3418da40-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:34190876-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:34193602-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.51']} DrugCentral uuid:34196370-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:341990f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3419c180-7972-11ec-93d9-0242ac110002 UniProtKB:Q62205 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3419ef5c-7972-11ec-93d9-0242ac110002 UniProtKB:A2APX8 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:341a1cca-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:341a4ab0-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:341a781e-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:341aa5b4-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:341ad340-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:341afcb2-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:341b2a3e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:341b57c0-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:341b8600-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:341bb36e-7972-11ec-93d9-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:341be0d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:341c0e54-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:341c3c4e-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:341c6ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:341c9856-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:341cc682-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:341cf40e-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:341d2212-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:341d507a-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:341d7e06-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:341dac6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:341dda04-7972-11ec-93d9-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:341e0948-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:341e36ca-7972-11ec-93d9-0242ac110002 UniProtKB:P02768 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:341e6438-7972-11ec-93d9-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:341e925a-7972-11ec-93d9-0242ac110002 UniProtKB:P14778 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Membrane receptor (Interleukin-1 receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:341ebfc8-7972-11ec-93d9-0242ac110002 UniProtKB:P41222 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:341f0690-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:341f0690-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:341f0690-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:341f0690-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:341f0690-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:341f0690-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:341f0690-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:341f77d8-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:341fa564-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:341fd35e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.319']} DrugCentral uuid:342000f4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:34202e76-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.149']} DrugCentral uuid:34205c84-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:34208b5a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:3420b90e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:3420e6cc-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:34211610-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.175']} DrugCentral uuid:342143ba-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:34217178-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:34219fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:3421cd4e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3421fac6-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.245']} DrugCentral uuid:34222870-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.003']} DrugCentral uuid:3422566a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.125']} DrugCentral uuid:34228400-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.465']} DrugCentral uuid:3422b1a0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:3422e076-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.526']} DrugCentral uuid:34230e2a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.541']} DrugCentral uuid:34233bca-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:34236a1e-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:342397c8-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:3423c572-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3423f31c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:3424227e-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:34245000-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:34247db4-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3424acda-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3424da84-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:34250932-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:342536d2-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3425654e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:342592d0-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3425c106-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3425ef14-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:34261c96-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:34264a36-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:342678da-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3426a9fe-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3426d7da-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:34270566-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:3427336a-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:342760f6-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:34278e8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3427bcb8-7972-11ec-93d9-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3427ea26-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:34281c1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:34281c1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:3428650a-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3428650a-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3428650a-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3428650a-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3428c3ba-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3428c3ba-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3428c3ba-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:34291716-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:34291716-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:34291716-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3429641e-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3429641e-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3429a852-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3429a852-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3429a852-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3429f6f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3429f6f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:342a3484-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NG02 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (G-protein coupled receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:342a6242-7972-11ec-93d9-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:342a8fe2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:342abe2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:342aebc2-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:342b1930-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:342b46bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:342b74c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:342ba256-7972-11ec-93d9-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:342bd00a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:342bff12-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:342c2c8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:342c5a16-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:342c87c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:342cb7cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:342ce562-7972-11ec-93d9-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:342d13ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:342d41e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07652 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is gating inhibitor of Ion channel (Voltage-dependent R-type calcium channel subunit alpha-1E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:342d6f6e-7972-11ec-93d9-0242ac110002 UniProtKB:P54282 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is gating inhibitor of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:342d9d9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:342dcc7a-7972-11ec-93d9-0242ac110002 UniProtKB:P15390 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:342dfa74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:342e281e-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.602']} DrugCentral uuid:342e55aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AIC4 biolink:molecularly_interacts_with DrugCentral:1798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 micafungin targets Unclassified (Beta-1,3-glucan synthase) DrugCentral uuid:342e7f4e-7972-11ec-93d9-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:1798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 micafungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) DrugCentral uuid:342ea82a-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.715']} DrugCentral uuid:342ed5b6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.137']} DrugCentral uuid:342f03ec-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.588']} DrugCentral uuid:342f31a0-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:342f5f4a-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:342f8cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.505']} DrugCentral uuid:342fbce2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:342fea82-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:34301836-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:343047ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:343070ba-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:34309e50-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:3430cbd2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.535']} DrugCentral uuid:3430f9ea-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.183']} DrugCentral uuid:343128b6-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.952']} DrugCentral uuid:3431566a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.452']} DrugCentral uuid:34318518-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.555']} DrugCentral uuid:3431b2cc-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:3431e08a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.785']} DrugCentral uuid:34320ede-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.964']} DrugCentral uuid:34323ca6-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.178']} DrugCentral uuid:34326a32-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:343297e6-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:3432c5fe-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.175']} DrugCentral uuid:3432f43e-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.351']} DrugCentral uuid:343321e8-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.386']} DrugCentral uuid:3433515e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.869']} DrugCentral uuid:34337f08-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3433ac80-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.136']} DrugCentral uuid:3433da2a-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.799']} DrugCentral uuid:34340874-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.271']} DrugCentral uuid:3434361e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.825']} DrugCentral uuid:343463c8-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:34349212-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:3434bae4-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.923']} DrugCentral uuid:3434e898-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:34351610-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.729']} DrugCentral uuid:343544a0-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:34357222-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:34359fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.534']} DrugCentral uuid:3435cefc-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3435fc9c-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:34362a46-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:34365868-7972-11ec-93d9-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:343685f4-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.381']} DrugCentral uuid:3436b38a-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.562']} DrugCentral uuid:3436e242-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:343710f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:34373e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:34376c12-7972-11ec-93d9-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.109']} DrugCentral uuid:34379a52-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.792']} DrugCentral uuid:3437c7d4-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.326']} DrugCentral uuid:3437f574-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.029']} DrugCentral uuid:34382332-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.922']} DrugCentral uuid:34385154-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.674']} DrugCentral uuid:34387efe-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.792']} DrugCentral uuid:3438ac9e-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.692']} DrugCentral uuid:3438dc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.711']} DrugCentral uuid:343909c8-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:3439377c-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:3439665c-7972-11ec-93d9-0242ac110002 UniProtKB:P22443 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:343993c0-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3439c11a-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3439eeba-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:343a1cc8-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:343a4b6c-7972-11ec-93d9-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:343a78f8-7972-11ec-93d9-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:343aa7c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:343ad55a-7972-11ec-93d9-0242ac110002 UniProtKB:K4CF70 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Fatty acid hydroperoxide lyase, chloroplastic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:343b02e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:343b3068-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['6']} DrugCentral uuid:343b5ec6-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.353']} DrugCentral uuid:343b8c7a-7972-11ec-93d9-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343bba1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:343bf0d4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:343bf0d4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:343bf0d4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:343c42dc-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:343c42dc-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:343c42dc-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:343c97fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:343c97fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:343c97fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343d20d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:343e257a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:343e257a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:343e257a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:343e7a02-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:343e7a02-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:343e7a02-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:343ecb7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:343ecb7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:343ecb7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:343f1dcc-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:343f1dcc-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:343f1dcc-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:343f6f16-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:343f6f16-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:343f6f16-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:343fb9bc-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midodrine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:343fe284-7972-11ec-93d9-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midodrine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:34401024-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.001']} DrugCentral uuid:34403f86-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.957']} DrugCentral uuid:34406d1c-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:34409ac6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.918']} DrugCentral uuid:3440c9c4-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is antagonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3440f89a-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34412612-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:34415434-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:344181ca-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3441af4c-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:3441dd0a-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is antagonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:34420e24-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:34423c32-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:344269c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.081']} DrugCentral uuid:344297d6-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.255']} DrugCentral uuid:3442c576-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.256']} DrugCentral uuid:3442f302-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.374']} DrugCentral uuid:344320b6-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:34434eb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q63449 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.46']} DrugCentral uuid:34437c32-7972-11ec-93d9-0242ac110002 UniProtKB:P21447 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transporter (P-glycoprotein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3443a9be-7972-11ec-93d9-0242ac110002 UniProtKB:F1Q298 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3443d998-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1U3 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:34440882-7972-11ec-93d9-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol is inhibitor of Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3444360e-7972-11ec-93d9-0242ac110002 UniProtKB:P04746 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Pancreatic alpha-amylase) DrugCentral uuid:34445f8a-7972-11ec-93d9-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:34448d02-7972-11ec-93d9-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol is inhibitor of Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3444ba7a-7972-11ec-93d9-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3444e7e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:344515f6-7972-11ec-93d9-0242ac110002 UniProtKB:P35574 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:34454378-7972-11ec-93d9-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34457118-7972-11ec-93d9-0242ac110002 UniProtKB:P09848 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:34459fee-7972-11ec-93d9-0242ac110002 UniProtKB:Q58D55 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:3445cdfc-7972-11ec-93d9-0242ac110002 UniProtKB:C0HJB3 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Alpha-mannosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:3445fb74-7972-11ec-93d9-0242ac110002 UniProtKB:P56526 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:344628ba-7972-11ec-93d9-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:34465704-7972-11ec-93d9-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat is inhibitor of Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3446847c-7972-11ec-93d9-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3446b1f4-7972-11ec-93d9-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3446dfda-7972-11ec-93d9-0242ac110002 UniProtKB:Q69ZF3 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:34470d3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:34473ab6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCG7 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:34476946-7972-11ec-93d9-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:344799d4-7972-11ec-93d9-0242ac110002 UniProtKB:P35573 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3447c8aa-7972-11ec-93d9-0242ac110002 UniProtKB:P70699 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3447f636-7972-11ec-93d9-0242ac110002 UniProtKB:B5THE3 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3448246c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9LGC6 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Putative alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:344851f8-7972-11ec-93d9-0242ac110002 UniProtKB:O70282 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Trehalase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:34487f7a-7972-11ec-93d9-0242ac110002 UniProtKB:I3LIR5 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:3448ae64-7972-11ec-93d9-0242ac110002 UniProtKB:O88693 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:3448dbd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3449097c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3449373a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:34496728-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:344994b4-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:3449c24a-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:3449f062-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:344a1dda-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:344a4b66-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:344a796a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:344aa700-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:344ad478-7972-11ec-93d9-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:344b01fa-7972-11ec-93d9-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:344b3044-7972-11ec-93d9-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:344b5de4-7972-11ec-93d9-0242ac110002 UniProtKB:O89085 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:344b9098-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:344b9098-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:344bd968-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:344bd968-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:344bd968-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:344bd968-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:344c2fd0-7972-11ec-93d9-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:1810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miltefosine targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:344c5db6-7972-11ec-93d9-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miltefosine targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:344c8b2e-7972-11ec-93d9-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Serine hydroxymethyltransferase, cytosolic) DrugCentral uuid:344cb4e6-7972-11ec-93d9-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:344ce25e-7972-11ec-93d9-0242ac110002 UniProtKB:P08543 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:344d1260-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:344d3fc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:344d6d28-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:344d9b54-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:344dc8b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:344df798-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:344e257e-7972-11ec-93d9-0242ac110002 UniProtKB:P02980 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Transporter (Tetracycline resistance protein, class B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.638']} DrugCentral uuid:344e52f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z7H2 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Unclassified (30S ribosomal protein S4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ka', 'has_quantitative_value': ['6']} DrugCentral uuid:344e8118-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z8T8 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Unclassified (30S ribosomal protein S9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ka', 'has_quantitative_value': ['5.756']} DrugCentral uuid:344eaea4-7972-11ec-93d9-0242ac110002 UniProtKB:P48048 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil targets Ion channel (ATP-sensitive inward rectifier potassium channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:344ee2a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) DrugCentral uuid:344ee2a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) DrugCentral uuid:344f174a-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:344f44e0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:344f7366-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:344fa0f2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:344fce92-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:344ffcd2-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:34502aa4-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:34505862-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:34508602-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3450b6b8-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:3450e44e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:345111ee-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:3451415a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:34516a0e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:345192ea-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3451c0a8-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3451eec0-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:34521c6a-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:34524a1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:3452787c-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3452a612-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:3452dc36-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3452dc36-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3452dc36-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3453260a-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:345353aa-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:3453814a-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3453af44-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.028']} DrugCentral uuid:3453e144-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitiglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3453e144-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitiglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:34541c68-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitomycin targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:34544d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:34547b90-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:3454a912-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:3454d73e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.512']} DrugCentral uuid:345504f2-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.186']} DrugCentral uuid:34553292-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:34555ff6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:34558fbc-7972-11ec-93d9-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) DrugCentral uuid:3455b88e-7972-11ec-93d9-0242ac110002 UniProtKB:P10109 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Unclassified (Adrenodoxin, mitochondrial) DrugCentral uuid:3455e16a-7972-11ec-93d9-0242ac110002 UniProtKB:P05108 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane is inhibitor of Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) DrugCentral uuid:34560a28-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.532']} DrugCentral uuid:345638e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.841']} DrugCentral uuid:3456664e-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.306']} DrugCentral uuid:345693d0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.729']} DrugCentral uuid:3456c224-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.744']} DrugCentral uuid:3456efba-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:34571d46-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.047']} DrugCentral uuid:34574b36-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:3457741c-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC90', 'has_quantitative_value': ['5.959']} DrugCentral uuid:3457a19e-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.287']} DrugCentral uuid:3457cf34-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kact', 'has_quantitative_value': ['5.155']} DrugCentral uuid:3457fe82-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.269']} DrugCentral uuid:34582c04-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3458599a-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.691']} DrugCentral uuid:345887ee-7972-11ec-93d9-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3458b566-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:3458e2d4-7972-11ec-93d9-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3459104c-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.748']} DrugCentral uuid:34593e32-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:34596b96-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3459990e-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3459c820-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:3459f692-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:345a23ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:345a5164-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:345a7f4a-7972-11ec-93d9-0242ac110002 UniProtKB:P29372 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (DNA-3-methyladenine glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:345aaccc-7972-11ec-93d9-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:345adc2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:345b0e56-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:345b0e56-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:345b0e56-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:345b4f10-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.456']} DrugCentral uuid:345b7c9c-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:345ba852-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:345bd638-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:345c03ba-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:345c3272-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:345c6030-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:345c8dc6-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:345cbb66-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:345ce9ba-7972-11ec-93d9-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:345d173c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:345d44c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:345d73da-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:345d9cac-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.396']} DrugCentral uuid:345dca24-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:345df300-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:345e20f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:345e4f8a-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moexipril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:345e7d16-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:345eab60-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:345ed900-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:345f0682-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:345f3422-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.157']} DrugCentral uuid:345f6596-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:345f937c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:345fc108-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.421']} DrugCentral uuid:345fef2a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:34601cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:34604a4c-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:346078a0-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:3460a62c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:3460d3c2-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.254']} DrugCentral uuid:3461014e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:346132ae-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3461622e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:34618fba-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.763']} DrugCentral uuid:3461bdbe-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3461eb40-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:346218cc-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3462472a-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:346274fc-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molsidomine targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:3462a274-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:3462d118-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:3462ff94-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:34632d16-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.429']} DrugCentral uuid:34635aa2-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.992']} DrugCentral uuid:34638888-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.414']} DrugCentral uuid:3463b632-7972-11ec-93d9-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:3463dfae-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.311']} DrugCentral uuid:34640d4e-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:34643bac-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.833']} DrugCentral uuid:34646960-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.574']} DrugCentral uuid:346496f6-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3464c69e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:3464f4c0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.713']} DrugCentral uuid:34652260-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.853']} DrugCentral uuid:34655000-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.495']} DrugCentral uuid:34657dfa-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.115']} DrugCentral uuid:3465ab9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:3465d93a-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:3466078e-7972-11ec-93d9-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.958']} DrugCentral uuid:34663538-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.772']} DrugCentral uuid:346662e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:346691ea-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.328']} DrugCentral uuid:3466bf94-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.495']} DrugCentral uuid:3466ed34-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:34671aac-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.817']} DrugCentral uuid:346749aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:34677740-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.068']} DrugCentral uuid:3467a4cc-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.895']} DrugCentral uuid:3467d2f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:346801ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:34682f78-7972-11ec-93d9-0242ac110002 UniProtKB:Q6NS65 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast is antagonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:34685d36-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:34688cac-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:3468ba38-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.134']} DrugCentral uuid:3468e7b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moracizine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:346910f0-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.86']} DrugCentral uuid:34693e5e-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:34696be0-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:34699a48-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:3469c7ca-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:3469f54c-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:346a23be-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:346a546a-7972-11ec-93d9-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:346a826e-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:346ab09a-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:346ade94-7972-11ec-93d9-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:346b0c20-7972-11ec-93d9-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:346b39c0-7972-11ec-93d9-0242ac110002 UniProtKB:P79350 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:346b6742-7972-11ec-93d9-0242ac110002 UniProtKB:P47748 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:346ba22a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:346ba22a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:346ba22a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:346ba22a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:346c0b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:346c0b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:346c0b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:346c0b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:346c0b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:346c7baa-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:346c7baa-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:346c7baa-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:346c7baa-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:346cd258-7972-11ec-93d9-0242ac110002 UniProtKB:Q98UH1 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu opioid receptor-like OR2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:346cfff8-7972-11ec-93d9-0242ac110002 UniProtKB:B3DH72 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor, delta 1b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:346d2d8e-7972-11ec-93d9-0242ac110002 UniProtKB:O57585 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor homologue) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:346d5bce-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapramine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:346d8964-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapramine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:346db84e-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:346de6e8-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:346e1492-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.891']} DrugCentral uuid:346e423c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:346e6fdc-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:346e9db8-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.694']} DrugCentral uuid:346ecb62-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.725']} DrugCentral uuid:346ef90c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.683']} DrugCentral uuid:346f276a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:346f5500-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:346f83c2-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:346fb1da-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:346fdff2-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:347011a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:347011a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:34704d48-7972-11ec-93d9-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:34707afc-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.938']} DrugCentral uuid:3470a8b0-7972-11ec-93d9-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.716']} DrugCentral uuid:3470d646-7972-11ec-93d9-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.637']} DrugCentral uuid:3471045e-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:34712d26-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:34715ab2-7972-11ec-93d9-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:34718e10-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:34718e10-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:3471c84e-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3471c84e-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3472037c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:347231a8-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.397']} DrugCentral uuid:34725f3e-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:34728ce8-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3472ba88-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3472e88c-7972-11ec-93d9-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:34731640-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine is agonist of Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:347343ea-7972-11ec-93d9-0242ac110002 UniProtKB:P00956 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:34737234-7972-11ec-93d9-0242ac110002 UniProtKB:P41252 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:34739fc0-7972-11ec-93d9-0242ac110002 UniProtKB:P41972 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin is inhibitor of Enzyme (Isoleucine--tRNA ligase) DrugCentral uuid:3473c8a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99YW3 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin is inhibitor of Enzyme (Isoleucine--tRNA ligase) DrugCentral uuid:3473f286-7972-11ec-93d9-0242ac110002 UniProtKB:P56690 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:34742242-7972-11ec-93d9-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolate mofetil is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:34744ff6-7972-11ec-93d9-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:1859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolate mofetil is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:34747d96-7972-11ec-93d9-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3474abae-7972-11ec-93d9-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3474ddb8-7972-11ec-93d9-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase (IMPDH)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3474ddb8-7972-11ec-93d9-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase (IMPDH)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:347518f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q5KP44 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Unclassified (Inosine-5'-monophosphate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:347548b6-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone is agonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:3475764c-7972-11ec-93d9-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3475a3a6-7972-11ec-93d9-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:3475d1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3475ff54-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:34762812-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.34']} DrugCentral uuid:34765594-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.732']} DrugCentral uuid:3476838e-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:3476b0f2-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.001']} DrugCentral uuid:3476de92-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:34770d90-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:34773b6c-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34776902-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3477967a-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3477c4c4-7972-11ec-93d9-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3477f246-7972-11ec-93d9-0242ac110002 UniProtKB:P06870 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Kallikrein-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:34781fd2-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:34784eda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:34787cfc-7972-11ec-93d9-0242ac110002 UniProtKB:P00736 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Complement C1r subcomponent) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3478aa88-7972-11ec-93d9-0242ac110002 UniProtKB:P09871 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Complement C1s subcomponent) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3478d81e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16515 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:3479064a-7972-11ec-93d9-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:347933d6-7972-11ec-93d9-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3479620c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3479904c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15661 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Tryptase alpha/beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:3479bdd8-7972-11ec-93d9-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:3479eb64-7972-11ec-93d9-0242ac110002 UniProtKB:Q04756 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Hepatocyte growth factor activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:347a1990-7972-11ec-93d9-0242ac110002 UniProtKB:O15393 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Transmembrane protease serine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:347a4726-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafarelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.699']} DrugCentral uuid:347a74a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:347ab076-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:347ab076-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:347ab076-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:347ab076-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:347ab076-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:347b0c74-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftidrofuryl targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:347b3a28-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:347b689a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:347b9630-7972-11ec-93d9-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (Squalene monooxygenase) DrugCentral uuid:347bbf0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:347be84c-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:347c1600-7972-11ec-93d9-0242ac110002 UniProtKB:O07855 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (Dehydrosqualene desaturase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:347c438c-7972-11ec-93d9-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:347c79a6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:347c79a6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:347c79a6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:347cd0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:347cd0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:347cd0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:347d1a00-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:347d487c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:347d763a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:347da3e4-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:347dd210-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:347dffce-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:347e2d82-7972-11ec-93d9-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:347e5c44-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:347e8ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:347e8ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:347ec378-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.53']} DrugCentral uuid:347ef14a-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:347f203e-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:347f4de8-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:347f7b88-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:347fa9a0-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:347fd74a-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:348004fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:348033de-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:34806304-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3480909a-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3480bf20-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3480fa08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3480fa08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3480fa08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3480fa08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:34815cdc-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:34815cdc-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:34815cdc-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:34815cdc-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:3481b394-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:3481e12a-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:3482106e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:34823df0-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:34826b90-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:34829912-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3482c734-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3482f63c-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:348323c8-7972-11ec-93d9-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:348351cc-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:34837f44-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:3483acc6-7972-11ec-93d9-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:3483db6a-7972-11ec-93d9-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3484091e-7972-11ec-93d9-0242ac110002 UniProtKB:P79350 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3484368c-7972-11ec-93d9-0242ac110002 UniProtKB:P51682 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.98']} DrugCentral uuid:348470d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:348470d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:348470d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:348470d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:3484c912-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:3484f1d0-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:34851fca-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34854d56-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:34857aba-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.678']} DrugCentral uuid:3485a850-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:3485d96a-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:34860354-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:348630ea-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34866024-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:34868d7e-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:3486bb1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:3486e922-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone phenpropionate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:348716c2-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone phenpropionate is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.5']} DrugCentral uuid:34874458-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3487720c-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3487a326-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:3487d080-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:3487fdee-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:34882bd4-7972-11ec-93d9-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:34885960-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:34888782-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3488b504-7972-11ec-93d9-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3488e83a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3488e83a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3489234a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:34895108-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:34898038-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.796']} DrugCentral uuid:3489adba-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3489db5a-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:348a09b8-7972-11ec-93d9-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:348a3ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:348a3ba4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:348a7b3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:348a7b3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:348ab6ec-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:348ae496-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:348b122c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:348b426a-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:348b7046-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:348b9ddc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:1889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nedocromil targets GPCR (Cysteinyl leukotriene receptor 1) DrugCentral uuid:348bc76c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nedocromil is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.013']} DrugCentral uuid:348bf4da-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:348c2266-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:348c5164-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.699']} DrugCentral uuid:348c7f90-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.444']} DrugCentral uuid:348cad1c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:348cdad0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:348d0bc2-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.143']} DrugCentral uuid:348d399e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.789']} DrugCentral uuid:348d6734-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.635']} DrugCentral uuid:348d956a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:348dc378-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.444']} DrugCentral uuid:348df104-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:348e1e86-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:348e4c80-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:348e7a16-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:348ea7ca-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:348ed6e6-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:348f04b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:348f3230-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:348f5fa8-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:348f8d98-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:348fbb24-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:348fe3e2-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:349011dc-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:34903f68-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:34906cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.481']} DrugCentral uuid:34909a8a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.252']} DrugCentral uuid:3490ca64-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:3490f7dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.232']} DrugCentral uuid:3491257c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.189']} DrugCentral uuid:34915380-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:349181f2-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3491af74-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.057']} DrugCentral uuid:3491dd0a-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.209']} DrugCentral uuid:34920b04-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.592']} DrugCentral uuid:349238ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.909']} DrugCentral uuid:34926630-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.078']} DrugCentral uuid:34929510-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.842']} DrugCentral uuid:3492c2f6-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.632']} DrugCentral uuid:3492f08c-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.255']} DrugCentral uuid:34931fd0-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:349348ca-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.101']} DrugCentral uuid:34937656-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.098']} DrugCentral uuid:3493a3ec-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.676']} DrugCentral uuid:3493d1e6-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.648']} DrugCentral uuid:3493ff68-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.739']} DrugCentral uuid:34942cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:34945b98-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.615']} DrugCentral uuid:34948938-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:3494b6a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.236']} DrugCentral uuid:3494e504-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:34951330-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:349540b2-7972-11ec-93d9-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:34956e52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:34959c38-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3495c9e2-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:3495f76e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:3496273e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:34965510-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.31']} DrugCentral uuid:34968292-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:3496b03c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3496de2c-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:349706fe-7972-11ec-93d9-0242ac110002 UniProtKB:P08312 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Phenylalanine--tRNA ligase alpha subunit) DrugCentral uuid:34972fc6-7972-11ec-93d9-0242ac110002 UniProtKB:P07395 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Phenylalanine--tRNA ligase beta subunit) DrugCentral uuid:34975898-7972-11ec-93d9-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3497871e-7972-11ec-93d9-0242ac110002 UniProtKB:O95237 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Lecithin retinol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:3497b4a0-7972-11ec-93d9-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.81']} DrugCentral uuid:3497e2ea-7972-11ec-93d9-0242ac110002 UniProtKB:P48442 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:34981364-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:34984474-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:34987296-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:3498a086-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:3498cdea-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3498fb8a-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:349928f8-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:349956fc-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:349988d4-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:349988d4-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3499c9a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3499c9a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:349a085e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepinalone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:349a361c-7972-11ec-93d9-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nesiritide is agonist of Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:349a5eee-7972-11ec-93d9-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:349a8df6-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:349abb82-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:349ae940-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:349b1744-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:349b44bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets GPCR (Hydroxycarboxylic acid receptor 2) DrugCentral uuid:349b6e24-7972-11ec-93d9-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets GPCR (Hydroxycarboxylic acid receptor 3) DrugCentral uuid:349b96ec-7972-11ec-93d9-0242ac110002 UniProtKB:P40261 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Nicotinamide N-methyltransferase) DrugCentral uuid:349bc1f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15274 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Nicotinate-nucleotide pyrophosphorylase [carboxylating]) DrugCentral uuid:349beaca-7972-11ec-93d9-0242ac110002 UniProtKB:Q96EB6 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacetylase sirtuin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:349c1838-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IXJ6 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacetylase sirtuin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:349c4628-7972-11ec-93d9-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:349c7382-7972-11ec-93d9-0242ac110002 UniProtKB:P53686 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent deacetylase HST2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:349ca10e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NTG7 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent deacetylase sirtuin 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:349cce90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:349cfc94-7972-11ec-93d9-0242ac110002 UniProtKB:Q8I6E4 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Unclassified (Putative silent information regulator 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:349d2a16-7972-11ec-93d9-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:349d578e-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.377']} DrugCentral uuid:349d8696-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:349db42c-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:349de1c2-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:349e0a80-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:349e3866-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:349e65de-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.553']} DrugCentral uuid:349e9360-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.553']} DrugCentral uuid:349ec16e-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:349eef0e-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:349f1da8-7972-11ec-93d9-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:349f4b48-7972-11ec-93d9-0242ac110002 UniProtKB:O54698 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:349f79c4-7972-11ec-93d9-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:349fafb6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:349fafb6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:349fafb6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:34a00344-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:34a00344-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:34a00344-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:34a05498-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:34a05498-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:34a05498-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:34a0a236-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:34a0a236-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:34a0d6de-7972-11ec-93d9-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:34a10460-7972-11ec-93d9-0242ac110002 UniProtKB:P15385 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:34a1332c-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.046']} DrugCentral uuid:34a160a4-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:34a18e12-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:34a1bbbc-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34a1e9e8-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:34a21760-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34a244d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:34a272d2-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:34a2a0fe-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:34a2cf84-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:34a2fe64-7972-11ec-93d9-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:34a32f42-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:34a35cce-7972-11ec-93d9-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:34a38a5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5JUK3 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:34a3b8a4-7972-11ec-93d9-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:34a3e630-7972-11ec-93d9-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:34a413a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:34a441ac-7972-11ec-93d9-0242ac110002 UniProtKB:P48048 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Ion channel (ATP-sensitive inward rectifier potassium channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:34a46f2e-7972-11ec-93d9-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:34a49c88-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:34a4ca1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:34a4fa5c-7972-11ec-93d9-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.356']} DrugCentral uuid:34a527ac-7972-11ec-93d9-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:34a55538-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:34a58350-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:34a5b0be-7972-11ec-93d9-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.03']} DrugCentral uuid:34a5de4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:34a60d98-7972-11ec-93d9-0242ac110002 UniProtKB:P49582 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:34a63b42-7972-11ec-93d9-0242ac110002 UniProtKB:P43144 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:34a668b0-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit beta-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:34a69650-7972-11ec-93d9-0242ac110002 UniProtKB:P04757 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:34a6c580-7972-11ec-93d9-0242ac110002 UniProtKB:P12389 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:34a6f30c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WSF8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Unclassified (Soluble acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:34a72278-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:34a7505e-7972-11ec-93d9-0242ac110002 UniProtKB:P21687 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Enzyme (Lycopene cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:34a77de0-7972-11ec-93d9-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:34a7ab76-7972-11ec-93d9-0242ac110002 UniProtKB:P25162 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit beta-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:34a7d95c-7972-11ec-93d9-0242ac110002 UniProtKB:P09482 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:34a806e8-7972-11ec-93d9-0242ac110002 UniProtKB:O70174 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:34a838c0-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:34a838c0-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:34a879e8-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:34a879e8-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:34a8b930-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:34a8b930-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:34a8f936-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:34a8f936-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:34a9390a-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:34a9390a-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:34a97898-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:34a97898-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34a9e698-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:34aac54a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:34aac54a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:34ab06ae-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:34ab06ae-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:34ab461e-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:34ab461e-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:34ab85f2-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:34ab85f2-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:34abc562-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:34abc562-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:34ac118e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:34ac118e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:34ac118e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:34ac118e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:34ac118e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:34ac85c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:34ac85c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:34ac85c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:34ac85c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:34aceaa0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:34aceaa0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:34aceaa0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:34aceaa0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:34ad4518-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:34ad4518-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:34ad8d7a-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:34ad8d7a-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:34ad8d7a-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:34ad8d7a-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:34adf5f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:34adf5f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:34adf5f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:34adf5f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:34adf5f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:34ae59a8-7972-11ec-93d9-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:34ae8734-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:34aeb510-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34aee274-7972-11ec-93d9-0242ac110002 UniProtKB:Q62897 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:34af0ff6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34af3f30-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.089']} DrugCentral uuid:34af6cc6-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.65']} DrugCentral uuid:34af9b4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:34afc9be-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:34aff754-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:34b024fe-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.019']} DrugCentral uuid:34b05294-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.348']} DrugCentral uuid:34b080c0-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:34b0aef6-7972-11ec-93d9-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:34b0dc82-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:34b10a72-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:34b13808-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34b1658a-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:34b1930c-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.672']} DrugCentral uuid:34b1c2d2-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:34b1f02c-7972-11ec-93d9-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:34b21dae-7972-11ec-93d9-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34b24c02-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:34b2798e-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.355']} DrugCentral uuid:34b2a706-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is antagonist of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:34b2d4e2-7972-11ec-93d9-0242ac110002 UniProtKB:P16389 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:34b30282-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:34b32ffa-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.731']} DrugCentral uuid:34b35d90-7972-11ec-93d9-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:34b38cac-7972-11ec-93d9-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34b3ba42-7972-11ec-93d9-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is antagonist of Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:34b3e8be-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.821']} DrugCentral uuid:34b416ea-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:34b44480-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:34b47220-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:34b49fc0-7972-11ec-93d9-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:34b4cdce-7972-11ec-93d9-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:34b4fb8c-7972-11ec-93d9-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:34b52936-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:34b55848-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:34b585ca-7972-11ec-93d9-0242ac110002 UniProtKB:O35505 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:34b5bc02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:34b5bc02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:34b5bc02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:34b60f68-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:34b60f68-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:34b60f68-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:34b6591e-7972-11ec-93d9-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:34b6870e-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:34b6b4a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:34b6e226-7972-11ec-93d9-0242ac110002 UniProtKB:P16388 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:34b70fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P63142 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:34b74004-7972-11ec-93d9-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:34b76d90-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:34b79b12-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34b7ca60-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:34b7f7ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:34b82582-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:34b8534a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.037']} DrugCentral uuid:34b880cc-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.973']} DrugCentral uuid:34b8ae44-7972-11ec-93d9-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:34b8db94-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:34b90a10-7972-11ec-93d9-0242ac110002 UniProtKB:P51800 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Chloride channel protein ClC-Ka) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34b9377e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6UVM3 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Potassium channel subfamily T member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:34b964ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:34b99368-7972-11ec-93d9-0242ac110002 UniProtKB:P51801 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Chloride channel protein ClC-Kb) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34b9c0e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.55']} DrugCentral uuid:34b9ee6c-7972-11ec-93d9-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:1928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifuroxazide targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:34ba1bda-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:34ba49ca-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:34ba7756-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:34baa50a-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:34bad34a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:34bb00c2-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:34bb2e4e-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:34bb5bee-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:34bb8a42-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:34bbb7b0-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:34bbe546-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.83']} DrugCentral uuid:34bc1336-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:34bc42e8-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:34bc7074-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.33']} DrugCentral uuid:34bc9f36-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:34bcccfe-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:34bcfa80-7972-11ec-93d9-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:34bd280c-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:34bd5638-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:34bd83ce-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:34bdb150-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:34bddfd6-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:34be0d44-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.13']} DrugCentral uuid:34be3ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.387']} DrugCentral uuid:34be683e-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:34be99f8-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:34bec78e-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:34bef506-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:34bf2346-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:34bf50be-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.069']} DrugCentral uuid:34bf7e54-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:34bfac58-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:34bfd9e4-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:34c00752-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:34c034ca-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.318']} DrugCentral uuid:34c065d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:34c093fc-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.096']} DrugCentral uuid:34c0c296-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:34c0f0d6-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:34c11e58-7972-11ec-93d9-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:34c14be4-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:34c1795c-7972-11ec-93d9-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:34c1a74c-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.141']} DrugCentral uuid:34c1d4c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:34c20264-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:34c230cc-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:34c25e4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:34c28bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:34c2ba38-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:34c2e7a6-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:34c3167c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:34c343fe-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:34c37202-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:34c39f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:34c3cd1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:34c3fbc8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:34c42954-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:34c456cc-7972-11ec-93d9-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:34c4844e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:34c4b2b6-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:34c4e042-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:34c50dc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:34c53ce0-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:34c56a58-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:34c597ee-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34c5c746-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:34c5f568-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:34c622ea-7972-11ec-93d9-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:34c6506c-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:34c67eb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:34c6ac38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:34c6d9b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:34c707a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:34c73540-7972-11ec-93d9-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:34c76722-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:34c76722-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:34c7a3e0-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:34c7d176-7972-11ec-93d9-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:34c7fa52-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:34c82310-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:34c850e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:34c850e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:34c8856c-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:34c8b30c-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:34c8e106-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.927']} DrugCentral uuid:34c90e7e-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:34c93bd8-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:34c969dc-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:34c999a2-7972-11ec-93d9-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.632']} DrugCentral uuid:34c9c738-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:34c9f4ba-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:34ca22d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q2A865 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:34ca505e-7972-11ec-93d9-0242ac110002 UniProtKB:L8I2E6 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Dipeptidyl peptidase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.16']} DrugCentral uuid:34ca7df4-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.364']} DrugCentral uuid:34caac2a-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:34cad9a2-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:34cb0706-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.072']} DrugCentral uuid:34cb34a6-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:34cb65b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:34cb9018-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:34cbbda4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:34cbe6e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:34cc0fac-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34cc3d10-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.252']} DrugCentral uuid:34cc6aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34cc98dc-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:34ccc654-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:34ccf462-7972-11ec-93d9-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34cd22de-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:34cd5056-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:34cd7dec-7972-11ec-93d9-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:34cdab78-7972-11ec-93d9-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:34cdd990-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.642']} DrugCentral uuid:34ce0820-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.638']} DrugCentral uuid:34ce35a2-7972-11ec-93d9-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) DrugCentral uuid:34ce5f28-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.395']} DrugCentral uuid:34ce8cd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:34ceba72-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:34cee330-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:34cf1382-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34cf49b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:34cf49b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:34cf49b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:34cf92bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01815 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:34cfc066-7972-11ec-93d9-0242ac110002 UniProtKB:Q99246 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:34cfef32-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:34d01cc8-7972-11ec-93d9-0242ac110002 UniProtKB:Q968X7 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide is inhibitor of Enzyme (Pyruvate dehydrogenase [NADP(+)]) DrugCentral uuid:34d04662-7972-11ec-93d9-0242ac110002 UniProtKB:Q24982 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide is inhibitor of Enzyme (Pyruvate:ferredoxin oxidoreductase) DrugCentral uuid:34d06f2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q0P8E1 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide targets Enzyme (Pyruvate-flavodoxin oxidoreductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:34d09cca-7972-11ec-93d9-0242ac110002 UniProtKB:P32754 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone is inhibitor of Enzyme (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:34d0caf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q02110 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone targets Enzyme (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:34d0f88c-7972-11ec-93d9-0242ac110002 UniProtKB:P32755 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone targets Unclassified (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:34d12e88-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:34d12e88-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:34d12e88-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:34d18cde-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:34d18cde-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:34d18cde-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:34d18cde-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:34d18cde-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:34d18cde-7972-11ec-93d9-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:34d20024-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:34d22d92-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.081']} DrugCentral uuid:34d25b46-7972-11ec-93d9-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is blocker of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:34d288be-7972-11ec-93d9-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:34d2b3e8-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.921']} DrugCentral uuid:34d2e174-7972-11ec-93d9-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:34d30f14-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:34d33cf0-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.056']} DrugCentral uuid:34d36a90-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:34d39830-7972-11ec-93d9-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34d3c5a8-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:34d3f47e-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:34d4221e-7972-11ec-93d9-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34d44fc8-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34d47fde-7972-11ec-93d9-0242ac110002 UniProtKB:P21556 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:34d4b634-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:34d4b634-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:34d4b634-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:34d5001c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:34d53ac8-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:34d53ac8-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:34d53ac8-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:34d53ac8-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:34d5894c-7972-11ec-93d9-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:1949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurantoin targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:34d5b2c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurantoin targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:34d5e054-7972-11ec-93d9-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:1950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurazone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:34d6093a-7972-11ec-93d9-0242ac110002 UniProtKB:P83512 biolink:molecularly_interacts_with DrugCentral:1950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurazone targets Enzyme (Snake venom metalloproteinase Bap1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:34d636b2-7972-11ec-93d9-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:34d66d30-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:34d66d30-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:34d66d30-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:34d66d30-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:34d6b984-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:34d6e788-7972-11ec-93d9-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:34d71514-7972-11ec-93d9-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:34d742b4-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:34d77054-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:34d79e8a-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:34d7cc34-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nizatidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:34d7f9ca-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nizatidine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.251']} DrugCentral uuid:34d828c8-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:34d8567c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:34d88408-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:34d8b20c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:34d8dfb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:34d90d38-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['2.947']} DrugCentral uuid:34d93ac4-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.963']} DrugCentral uuid:34d9690e-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:34d996ae-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:34d9c552-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:34d9f4aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:34da26be-7972-11ec-93d9-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Hemoglobin HbA) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.678']} DrugCentral uuid:34da26be-7972-11ec-93d9-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Hemoglobin HbA) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.678']} DrugCentral uuid:34da620a-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norelgestromin is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:34da8bd6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:34dab994-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:34dae734-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.3']} DrugCentral uuid:34db14ca-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:34db4328-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:34db7230-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:34db9fc6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:34dbce74-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.367']} DrugCentral uuid:34dbfc28-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:34dc29aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.071']} DrugCentral uuid:34dc57b8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:34dc8576-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:34dcb30c-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:34dce0c0-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:34dd0f14-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:34dd3caa-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:34dd6a36-7972-11ec-93d9-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:34dd9920-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:34ddc6de-7972-11ec-93d9-0242ac110002 UniProtKB:P10608 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:34ddf474-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:34de2214-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:34de598c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:34de598c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:34de598c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:34deaae0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:34deaae0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:34deaae0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:34df09a4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:34df09a4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:34df09a4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:34df09a4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:34df09a4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:34df09a4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:34df851e-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34df851e-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34df851e-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:34dfce0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01337 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:34dffbb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:34e029c4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.618']} DrugCentral uuid:34e05750-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.706']} DrugCentral uuid:34e084e6-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.636']} DrugCentral uuid:34e0b452-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:34e0e1fc-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['11.26']} DrugCentral uuid:34e10f74-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.97']} DrugCentral uuid:34e13e54-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:34e16c8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.914']} DrugCentral uuid:34e19f5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:34e19f5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:34e1db02-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:34e20884-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.533']} DrugCentral uuid:34e2361a-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:34e263a6-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:34e291f0-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['11.26']} DrugCentral uuid:34e2bf72-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:34e2ed12-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.97']} DrugCentral uuid:34e31c92-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.149']} DrugCentral uuid:34e34a28-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.441']} DrugCentral uuid:34e377e6-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethynodrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:34e3a0b8-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethynodrel targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:34e3ce94-7972-11ec-93d9-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:34e3fc16-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:34e42a88-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:34e458d2-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:34e48668-7972-11ec-93d9-0242ac110002 UniProtKB:P0AFI2 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:34e4b3fe-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:34e4e266-7972-11ec-93d9-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:34e51060-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:34e53de2-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:34e56b6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:34e59954-7972-11ec-93d9-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:34e5c7ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e6354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34e73278-7972-11ec-93d9-0242ac110002 UniProtKB:P37340 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Unclassified (Multidrug resistance protein mdtK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.01']} DrugCentral uuid:34e76072-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:34e78958-7972-11ec-93d9-0242ac110002 UniProtKB:Q13507 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is blocker of Ion channel (Short transient receptor potential channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:34e7b702-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y210 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is blocker of Ion channel (Short transient receptor potential channel 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:34e7e498-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:34e812e2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:34e84096-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:34e86e40-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:34e89ef6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.36']} DrugCentral uuid:34e8cc8c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.509']} DrugCentral uuid:34e8fa40-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.356']} DrugCentral uuid:34e92876-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:34e95620-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:34e983e8-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:34e9b17e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:34e9dfdc-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:34ea0d9a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:34ea3b3a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.033']} DrugCentral uuid:34ea6a60-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.639']} DrugCentral uuid:34ea9bc0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:34eac97e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:34eaf714-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:34eb252c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.076']} DrugCentral uuid:34eb52cc-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:34eb8044-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.071']} DrugCentral uuid:34ebae7a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:34ebdc1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.921']} DrugCentral uuid:34ec09ba-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['6.225']} DrugCentral uuid:34ec3a0c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:34ec6810-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:34ec9592-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:34ecc332-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.943']} DrugCentral uuid:34ecf15e-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:34ed2020-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:34ed4db6-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:34ed7bec-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:34eda98c-7972-11ec-93d9-0242ac110002 UniProtKB:P78508 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.796']} DrugCentral uuid:34edd70e-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.087']} DrugCentral uuid:34ee0490-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:34ee333e-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:34ee60ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:34ee8e4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:34eebc46-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:34eee9dc-7972-11ec-93d9-0242ac110002 UniProtKB:P0A4L9 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:34ef1772-7972-11ec-93d9-0242ac110002 UniProtKB:Q7X1P7 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (ParE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:34ef45a8-7972-11ec-93d9-0242ac110002 UniProtKB:C3SLN2 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:34ef779e-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:34ef779e-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:34efb718-7972-11ec-93d9-0242ac110002 UniProtKB:Q5HK04 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:34efb718-7972-11ec-93d9-0242ac110002 UniProtKB:Q5HK04 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:34efed8c-7972-11ec-93d9-0242ac110002 UniProtKB:P0C559 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:34f01b0e-7972-11ec-93d9-0242ac110002 UniProtKB:P0A0K8 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:34f048b8-7972-11ec-93d9-0242ac110002 UniProtKB:A0QNE0 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNULL gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:34f07658-7972-11ec-93d9-0242ac110002 UniProtKB:C3SLN3 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNULL gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:34f0ad08-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:34f0ad08-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:34f0ad08-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:34f0f5d8-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:34f12436-7972-11ec-93d9-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.699']} DrugCentral uuid:34f152da-7972-11ec-93d9-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:34f1808e-7972-11ec-93d9-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:34f1ae24-7972-11ec-93d9-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:34f1df20-7972-11ec-93d9-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:34f20cca-7972-11ec-93d9-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:34f23a7e-7972-11ec-93d9-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.98']} DrugCentral uuid:34f268a0-7972-11ec-93d9-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:34f2978a-7972-11ec-93d9-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:34f2c53e-7972-11ec-93d9-0242ac110002 UniProtKB:P30936 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:34f2f3a6-7972-11ec-93d9-0242ac110002 UniProtKB:O08858 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:34f32150-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:34f34ef0-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:34f37d12-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:34f3ac06-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:34f3d97e-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:34f40232-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:34f4302c-7972-11ec-93d9-0242ac110002 UniProtKB:P03362 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Polyprotein (Gag-Pro-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f49d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:34f59a70-7972-11ec-93d9-0242ac110002 UniProtKB:P47154 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (CAAX prenyl protease 1) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:34f5c7c0-7972-11ec-93d9-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:34f5f4fc-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:34f6235a-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:34f650e6-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:34f67ea4-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.523']} DrugCentral uuid:34f6acb2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.492']} DrugCentral uuid:34f6da48-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:34f707c0-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:34f73614-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.9']} DrugCentral uuid:34f763aa-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.319']} DrugCentral uuid:34f79280-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:34f7c016-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:34f7ee60-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:34f81bec-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:34f84a4a-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:34f87844-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:34f8a6e8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:34f8d488-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:34f9021e-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:34f930e0-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.356']} DrugCentral uuid:34f95e62-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.506']} DrugCentral uuid:34f98bda-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.102']} DrugCentral uuid:34f9ba24-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.136']} DrugCentral uuid:34f9e7a6-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.682']} DrugCentral uuid:34fa1546-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:34fa4340-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:34fa70a4-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.233']} DrugCentral uuid:34fa9e12-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.121']} DrugCentral uuid:34facb9e-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:34fafa2e-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:34fb27d8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:34fb5564-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:34fb839a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:34fbb126-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.916']} DrugCentral uuid:34fbdeb2-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.509']} DrugCentral uuid:34fc0c48-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:34fc3a56-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.558']} DrugCentral uuid:34fc67e2-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:34fc9578-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.364']} DrugCentral uuid:34fcc53e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:34fcf342-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:34fd21dc-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:34fd5044-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:34fd7dee-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:34fdaba2-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:34fdd924-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:34fe0714-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:34fe34aa-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:34fe639e-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:34fe9224-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:34febfba-7972-11ec-93d9-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:34feed64-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:34ff1ae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:34ff51c8-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:34ff51c8-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:34ff51c8-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:34ffa33a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:34ffa33a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:34ffa33a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:34ffecd2-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:35001a4a-7972-11ec-93d9-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:35004880-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmesartan medoxomil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:350077d8-7972-11ec-93d9-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:1985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmesartan medoxomil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:3500a564-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olopatadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.284']} DrugCentral uuid:3500d304-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olopatadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:35010590-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olprinone is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:35010590-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olprinone is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:35013b64-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:35016454-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:350191d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:350191d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:3501c688-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3501f41e-7972-11ec-93d9-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:350221a0-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:350250d0-7972-11ec-93d9-0242ac110002 UniProtKB:P07861 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:35027e34-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3502abca-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3502da50-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.31']} DrugCentral uuid:350307d2-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.051']} DrugCentral uuid:35033554-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.347']} DrugCentral uuid:35036344-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:35039116-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:3503beb6-7972-11ec-93d9-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3503f098-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3503f098-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:350434cc-7972-11ec-93d9-0242ac110002 UniProtKB:P19156 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:350434cc-7972-11ec-93d9-0242ac110002 UniProtKB:P19156 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:35047022-7972-11ec-93d9-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:35049dfe-7972-11ec-93d9-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3504cba8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3504fd80-7972-11ec-93d9-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:3504fd80-7972-11ec-93d9-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:3505389a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:350567a2-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:3505954c-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.678']} DrugCentral uuid:3505c2ce-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3505f208-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:35061f76-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:35064d0c-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:35067b38-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:3506a8c4-7972-11ec-93d9-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3506d650-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:35070486-7972-11ec-93d9-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3507328a-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3507603e-7972-11ec-93d9-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:35078dd4-7972-11ec-93d9-0242ac110002 UniProtKB:P35563 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:3507bdcc-7972-11ec-93d9-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3507eba8-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35081934-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:350846b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:35087492-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:3508a660-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:3508a660-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:3508e666-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:3508e666-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:35092a18-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:35092a18-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:35092a18-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:35097856-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:35097856-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3509b4b0-7972-11ec-93d9-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3509e246-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:350a0ff0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:350a3f3e-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:350a6cc0-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:350a9a60-7972-11ec-93d9-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Lipoprotein lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.18']} DrugCentral uuid:350ac828-7972-11ec-93d9-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:350af58c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4D2 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:350b22d2-7972-11ec-93d9-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:350b502c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NCG7 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:350b7f20-7972-11ec-93d9-0242ac110002 UniProtKB:O95870 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Abhydrolase domain-containing protein 16A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:350bac7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N2K0 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Monoacylglycerol lipase ABHD12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:350bd9f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13093 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Platelet-activating factor acetylhydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:350c07e2-7972-11ec-93d9-0242ac110002 UniProtKB:P00591 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:350c3550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BV23 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Monoacylglycerol lipase ABHD6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:350c62be-7972-11ec-93d9-0242ac110002 UniProtKB:Q6WQJ1 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:350c9086-7972-11ec-93d9-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Lipoprotein lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.18']} DrugCentral uuid:350cbe8a-7972-11ec-93d9-0242ac110002 UniProtKB:P11150 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Hepatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:350cec0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5X9 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Endothelial lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:350d1970-7972-11ec-93d9-0242ac110002 UniProtKB:P16233 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat is inhibitor of Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.9']} DrugCentral uuid:350d4936-7972-11ec-93d9-0242ac110002 UniProtKB:P07098 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat is inhibitor of Enzyme (Gastric triacylglycerol lipase) DrugCentral uuid:350d71f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.886']} DrugCentral uuid:350d9f6c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.092']} DrugCentral uuid:350dce88-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.174']} DrugCentral uuid:350dfc00-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.614']} DrugCentral uuid:350e298c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.578']} DrugCentral uuid:350e5718-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.903']} DrugCentral uuid:350e8526-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.666']} DrugCentral uuid:350eb2a8-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.553']} DrugCentral uuid:350ee034-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.283']} DrugCentral uuid:350f0fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:350f3d90-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:350f6b1c-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.165']} DrugCentral uuid:350f9894-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:350fc666-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.873']} DrugCentral uuid:350ff3f2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:35102174-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:35104f64-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:35107cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.889']} DrugCentral uuid:3510aa7c-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:3510da9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.764']} DrugCentral uuid:35110814-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:35113596-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.201']} DrugCentral uuid:3511630e-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:351190ea-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:3511d7f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3511d7f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3511d7f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3511d7f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3511d7f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3511d7f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3511d7f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:35125994-7972-11ec-93d9-0242ac110002 UniProtKB:P06818 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.83']} DrugCentral uuid:35128702-7972-11ec-93d9-0242ac110002 UniProtKB:P16207 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3512b754-7972-11ec-93d9-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3512e4fe-7972-11ec-93d9-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3513128a-7972-11ec-93d9-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:35134002-7972-11ec-93d9-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:35136df2-7972-11ec-93d9-0242ac110002 UniProtKB:Q75VQ4 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.81']} DrugCentral uuid:35139b74-7972-11ec-93d9-0242ac110002 UniProtKB:Q6Q793 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:3513c8f6-7972-11ec-93d9-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3513f6f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q2LFS1 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3514247c-7972-11ec-93d9-0242ac110002 UniProtKB:C4LRQ6 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:351451fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q20MD3 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:351480c0-7972-11ec-93d9-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:3514ae38-7972-11ec-93d9-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3514dbb0-7972-11ec-93d9-0242ac110002 UniProtKB:P03469 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.86']} DrugCentral uuid:35150928-7972-11ec-93d9-0242ac110002 UniProtKB:Q07599 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3515372c-7972-11ec-93d9-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.96']} DrugCentral uuid:351564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XV28 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:35159244-7972-11ec-93d9-0242ac110002 UniProtKB:P11172 biolink:molecularly_interacts_with DrugCentral:2002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oteracil is inhibitor of Enzyme (Uridine 5'-monophosphate synthase) DrugCentral uuid:3515bb70-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.169']} DrugCentral uuid:3515e8f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.009']} DrugCentral uuid:3516164c-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:35164018-7972-11ec-93d9-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:35166e9e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:35169c16-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:3516c984-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:3516f418-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:35173284-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:35173284-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:35173284-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:35173284-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:35173284-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:35178b26-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3517b8c6-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3517ea9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3517ea9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:351826a8-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxandrolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:35185218-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:35187fb8-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.068']} DrugCentral uuid:3518ad44-7972-11ec-93d9-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets GPCR (fMet-Leu-Phe receptor) DrugCentral uuid:3518d68e-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3519049c-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3519320a-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:35196004-7972-11ec-93d9-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:35198d5e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.056']} DrugCentral uuid:3519baea-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.148']} DrugCentral uuid:3519e86c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:351a1828-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:351a45d2-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:351a7462-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:351aaafe-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:351aaafe-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:351aaafe-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:351af3ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxcarbazepine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:351b1ca0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphencyclimine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:351b45d6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphencyclimine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:351b6ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:351b9c70-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:351bca1a-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:351bf9ea-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:351c279e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.991']} DrugCentral uuid:351c5520-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.589']} DrugCentral uuid:351c8324-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.298']} DrugCentral uuid:351cb20e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.837']} DrugCentral uuid:351cdfb8-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:351d0df8-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:351d3b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:351d6924-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.168']} DrugCentral uuid:351d96ce-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:351dc5ae-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:351df344-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:351e20da-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:351e4eca-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:351e7c74-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:351eab2c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:351ed8e0-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:351f07de-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:351f354c-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:351f62b0-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:351f9168-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:351fbec2-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:351fec62-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:35201a5c-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:352047e8-7972-11ec-93d9-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:3520757e-7972-11ec-93d9-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3520a2f6-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:3520d15e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:3520ff12-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.493']} DrugCentral uuid:35212ca8-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:35215c8c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:35218a36-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3521b420-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.111']} DrugCentral uuid:3521dd42-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.342']} DrugCentral uuid:352206be-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.019']} DrugCentral uuid:35222fea-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:35225920-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:35228256-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3522ac36-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:3522d53a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3522ff4c-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:352329a4-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.379']} DrugCentral uuid:35235636-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:35237f58-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.162']} DrugCentral uuid:3523a88e-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.041']} DrugCentral uuid:3523d1f6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:3523fafa-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3524241c-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:35244d0c-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:352476e2-7972-11ec-93d9-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3524a018-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3524c93a-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:3524fb3a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3524fb3a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3524fb3a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3525445a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3525445a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3525445a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:352585b4-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3525afc6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3525d8de-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:3525fdb4-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:3526228a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:35264c7e-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:352675a0-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:35269ee0-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3526c910-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:3526f322-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:35271c58-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.27']} DrugCentral uuid:3527457a-7972-11ec-93d9-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:35276f28-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:35279854-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3527c176-7972-11ec-93d9-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:3527f614-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:3527f614-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:3527f614-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:3527f614-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:35284786-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:35284786-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:35287de6-7972-11ec-93d9-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets GPCR (fMet-Leu-Phe receptor) DrugCentral uuid:3528a370-7972-11ec-93d9-0242ac110002 UniProtKB:Q16647 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets Enzyme (Prostacyclin synthase) DrugCentral uuid:3528cc2e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:3528cc2e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:3528fb72-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3529248a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:352949c4-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:35296e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.84']} DrugCentral uuid:3529978a-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:2041 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytetracycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:3529bc42-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:2041 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytetracycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:3529e1a4-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:352a0a9e-7972-11ec-93d9-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:352a3384-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:352a5c6a-7972-11ec-93d9-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:352a8762-7972-11ec-93d9-0242ac110002 UniProtKB:P01178 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets Secreted (Oxytocin-neurophysin 1) DrugCentral uuid:352aafee-7972-11ec-93d9-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:352ad91a-7972-11ec-93d9-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:352b023c-7972-11ec-93d9-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin is agonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:352b2bae-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozagrel targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:352b549e-7972-11ec-93d9-0242ac110002 UniProtKB:P49430 biolink:molecularly_interacts_with DrugCentral:2043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozagrel targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:352b7da2-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:352ba6b0-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:352bd054-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:352bf962-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Bile salt export pump) DrugCentral uuid:352c1e1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:352c42d2-7972-11ec-93d9-0242ac110002 UniProtKB:P07437 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Structural (Tubulin beta chain) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352c6d02-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.621']} DrugCentral uuid:352c961a-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.954']} DrugCentral uuid:352cbf00-7972-11ec-93d9-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.643']} DrugCentral uuid:352ce87c-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:352d1180-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.794']} DrugCentral uuid:352d3a98-7972-11ec-93d9-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:352d63a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:352d8d4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13509 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Structural (Tubulin beta-3 chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:352db662-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352dfe38-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:352e8cd6-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:352eb5c6-7972-11ec-93d9-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:352ee35c-7972-11ec-93d9-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:352f0c60-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol is agonist of GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:352f356e-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.5']} DrugCentral uuid:352f62e6-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:352f62e6-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:352f97fc-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:2047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamabrom targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:352fc114-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:352fea36-7972-11ec-93d9-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3530151a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07010 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:35303e14-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:35306754-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:353091de-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:3530bae2-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3530e3f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q81VW8 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:35310d1c-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:353136ac-7972-11ec-93d9-0242ac110002 UniProtKB:P9WNC6 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid targets Kinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) DrugCentral uuid:35315b5a-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['2.92']} DrugCentral uuid:3531885a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:3531885a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:3531bf5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:3531bf5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:3531bf5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:35320a50-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:35320a50-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:35324ad8-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:35324ad8-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:35324ad8-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:35324ad8-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:35329a1a-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:3532bed2-7972-11ec-93d9-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3532e7f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:35331184-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:35333a7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:35336396-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:35339082-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:35339082-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:3533c232-7972-11ec-93d9-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:3533ef1e-7972-11ec-93d9-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3533ef1e-7972-11ec-93d9-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:35342452-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:35344e00-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:35347704-7972-11ec-93d9-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:35349ba8-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:3534c4b6-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3534ee28-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:35351740-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.118']} DrugCentral uuid:3535415c-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.088']} DrugCentral uuid:35356a60-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3535954e-7972-11ec-93d9-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3535be48-7972-11ec-93d9-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3535e77e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM07 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Protein-arginine deiminase type-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:35361136-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:35363a4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:35366348-7972-11ec-93d9-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35368c56-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QYJ6 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3536bd70-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3536bd70-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3536bd70-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:35370280-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:35370280-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:35373f2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:35373f2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:35373f2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3537811a-7972-11ec-93d9-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3537aa8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3537db4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:3537db4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:3537db4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:3538172e-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.854']} DrugCentral uuid:3538405a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:35386968-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:353893f2-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3538bcf6-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3538e618-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:35390f30-7972-11ec-93d9-0242ac110002 UniProtKB:P11884 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Aldehyde dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:35393910-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paricalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3539620a-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:35398b2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.647']} DrugCentral uuid:3539b43a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.068']} DrugCentral uuid:3539de42-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:353a0750-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.398']} DrugCentral uuid:353a305e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.52']} DrugCentral uuid:353a59c6-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:353a82fc-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:353aac14-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.724']} DrugCentral uuid:353ad54a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:353b0006-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:353b295a-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:353b5268-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:353b7b94-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:353ba52e-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:353bce3c-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:353bf754-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:353c204e-7972-11ec-93d9-0242ac110002 UniProtKB:P25098 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:353c49c0-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:353c72d8-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:353c9cc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:353cc6a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.36']} DrugCentral uuid:353cf03c-7972-11ec-93d9-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:353d1954-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:353d4258-7972-11ec-93d9-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:353d6c7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:353d9d48-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:353d9d48-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:353d9d48-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:353de794-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:353de794-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:353de794-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:353e2984-7972-11ec-93d9-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:353e52ba-7972-11ec-93d9-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:353e7bc8-7972-11ec-93d9-0242ac110002 UniProtKB:P21146 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:353ea62a-7972-11ec-93d9-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:353ecf88-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.785']} DrugCentral uuid:353ef882-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.097']} DrugCentral uuid:353f2190-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.785']} DrugCentral uuid:353f4b48-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.468']} DrugCentral uuid:353f7460-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.181']} DrugCentral uuid:353f9d64-7972-11ec-93d9-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:353fc2ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:353fec74-7972-11ec-93d9-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Serine hydroxymethyltransferase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:35401578-7972-11ec-93d9-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:35403e9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:354068a2-7972-11ec-93d9-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:354092b4-7972-11ec-93d9-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3540bbae-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3540e4a8-7972-11ec-93d9-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:35410e7e-7972-11ec-93d9-0242ac110002 UniProtKB:P45352 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3541378c-7972-11ec-93d9-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:354160ae-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:354189bc-7972-11ec-93d9-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3541b32e-7972-11ec-93d9-0242ac110002 UniProtKB:E2QDN0 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:3541dc00-7972-11ec-93d9-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.86']} DrugCentral uuid:354204e6-7972-11ec-93d9-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:35422dfe-7972-11ec-93d9-0242ac110002 UniProtKB:Q64737 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Trifunctional purine biosynthetic protein adenosine-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:35425838-7972-11ec-93d9-0242ac110002 UniProtKB:P22102 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Trifunctional purine biosynthetic protein adenosine-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3542815a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemoline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:3542aa68-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3542d39e-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3542fd60-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:35432682-7972-11ec-93d9-0242ac110002 UniProtKB:P02763 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets Secreted (Alpha-1-acid glycoprotein 1) DrugCentral uuid:35434b1c-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:3543756a-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:35439b12-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3543c402-7972-11ec-93d9-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:3543ecfc-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:35441628-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:35444062-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:35446970-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:354493aa-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3544bd76-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3544e68e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:35450fa6-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:354538c8-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3545626c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:35458b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3545b4b0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3545ddd2-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:35460866-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:35463192-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:35465ab4-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:354683c2-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3546ad84-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3546d69c-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3546ffbe-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3547294e-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:354761ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:354761ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:354761ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:354761ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:354761ca-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3547bb0c-7972-11ec-93d9-0242ac110002 UniProtKB:P44514 biolink:molecularly_interacts_with DrugCentral:2081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penicillamine targets Enzyme (Succinyl-diaminopimelate desuccinylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3547e654-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:35480b16-7972-11ec-93d9-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:35483442-7972-11ec-93d9-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:354875e2-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:354875e2-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:354875e2-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:354875e2-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:354875e2-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:354875e2-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:354875e2-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:3548daf0-7972-11ec-93d9-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:35490458-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:35493ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:35493ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:35493ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:35493ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:35493ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:35493ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:35493ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:3549a606-7972-11ec-93d9-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:3549cf14-7972-11ec-93d9-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3549f818-7972-11ec-93d9-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:354a211c-7972-11ec-93d9-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:354a4a98-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.287']} DrugCentral uuid:354a73ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:354a9ce6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:354ac612-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:354aefb6-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.765']} DrugCentral uuid:354b18ec-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.867']} DrugCentral uuid:354b4222-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.295']} DrugCentral uuid:354b6bda-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:354b9628-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.683']} DrugCentral uuid:354bbf54-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:354be880-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:354c11fc-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.101']} DrugCentral uuid:354c3af6-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:354c63d2-7972-11ec-93d9-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:354c8cd6-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:354cb68e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:354cdf9c-7972-11ec-93d9-0242ac110002 UniProtKB:P04271 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Cytosolic other (Protein S100-B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:354d08d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:354d31d6-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:354d5d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P19801 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Amiloride-sensitive amine oxidase [copper-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:354d87b2-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:354db0ca-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:354dd9d8-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:354e0354-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:354e2c62-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:354e555c-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:354e960c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:354e960c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:354e960c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:354e960c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:354e960c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:354e960c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:354e960c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:354f0ce0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:354f0ce0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:354f434a-7972-11ec-93d9-0242ac110002 UniProtKB:P21673 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Spermidine/spermine N(1)-acetyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:354f6c62-7972-11ec-93d9-0242ac110002 UniProtKB:O75365 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein-tyrosine phosphatase 4A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:354f9570-7972-11ec-93d9-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:354fbece-7972-11ec-93d9-0242ac110002 UniProtKB:P04631 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Unclassified (Protein S100-B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.36']} DrugCentral uuid:354fe7e6-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:355010ea-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:355039d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12974 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein tyrosine phosphatase type IVA 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:35506374-7972-11ec-93d9-0242ac110002 UniProtKB:Q93096 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein tyrosine phosphatase type IVA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:35508c8c-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:3550b590-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.553']} DrugCentral uuid:3550e650-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:3550e650-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:3550e650-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35516350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35524cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:35524cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:35524cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:35528db6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:3552b674-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:3552b674-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:3552e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:2098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentostatin is inhibitor of Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.8']} DrugCentral uuid:35531344-7972-11ec-93d9-0242ac110002 UniProtKB:P56658 biolink:molecularly_interacts_with DrugCentral:2098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentostatin targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:35533cde-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:35536650-7972-11ec-93d9-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:35538b1c-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3553b42a-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) DrugCentral uuid:3553d8f6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:355402a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:35542ba8-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:355454ca-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:35547dc4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3554a862-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3554d18e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:3554fbd2-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:355524f4-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:35554e70-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:35557774-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:3555a0a0-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3555c99a-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3555f35c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:35561c92-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:35564582-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:35567084-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:35569a00-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3556c318-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.838']} DrugCentral uuid:3556ed7a-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:355716e2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:35573fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:355768d6-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:355791e4-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3557bbb0-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3557e4aa-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:35580db8-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:35583f90-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:35583f90-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:35583f90-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:355884c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:355884c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3558c906-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:3558c906-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:3558c906-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:3558c906-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:3558c906-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:355927a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:355927a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:35595cc2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:35598698-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3559afa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.962']} DrugCentral uuid:3559d8dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:355a01f4-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.486']} DrugCentral uuid:355a2ddc-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:355a5870-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:355a8174-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:355aaa8c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.105']} DrugCentral uuid:355ad426-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.027']} DrugCentral uuid:355afd20-7972-11ec-93d9-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:355b21f6-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:355b4bcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) DrugCentral uuid:355b7098-7972-11ec-93d9-0242ac110002 UniProtKB:P50416 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 1, liver isoform) DrugCentral uuid:355b955a-7972-11ec-93d9-0242ac110002 UniProtKB:P23786 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:355bbe7c-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.828']} DrugCentral uuid:355be848-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.391']} DrugCentral uuid:355c1296-7972-11ec-93d9-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:355c434c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:355c434c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:355c434c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:355c8636-7972-11ec-93d9-0242ac110002 UniProtKB:P18886 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine palmitoyltransferase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:355cafc6-7972-11ec-93d9-0242ac110002 UniProtKB:P32198 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine palmitoyltransferase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:355cd8de-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:355d01e2-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:355d2b90-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:355d549e-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:355d7db6-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2108 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perindopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:355da6ba-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:355dd22a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.704']} DrugCentral uuid:355dfb6a-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.824']} DrugCentral uuid:355e248c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:355e4e4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:355e77b6-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:355ea0ba-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:355ec9d2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:355ef362-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:355f1c98-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:355f45c4-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:355f6ef0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:355f993e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:355fc26a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.462']} DrugCentral uuid:355feb82-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:356014a4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:35603efc-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:35606814-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:35609136-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:3560ba58-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3560e438-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:35610d46-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.521']} DrugCentral uuid:35613668-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.088']} DrugCentral uuid:35615f80-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.733']} DrugCentral uuid:3561896a-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.481']} DrugCentral uuid:3561b25a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3561db72-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.588']} DrugCentral uuid:3562062e-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:35622f5a-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:35625890-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:356281b2-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacemide is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:3562a6ec-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacetin targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:3562cba4-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3562f4d0-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:35631df2-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3563487c-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:35637194-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3563bcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3564420e-7972-11ec-93d9-0242ac110002 UniProtKB:P83512 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine targets Enzyme (Snake venom metalloproteinase Bap1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:35646b9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:356495f6-7972-11ec-93d9-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:3564bf18-7972-11ec-93d9-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3564e830-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:35651238-7972-11ec-93d9-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:35653bb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:35656544-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3565a554-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3565a554-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3565a554-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3565a554-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3565a554-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3565a554-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3565a554-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:35662e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:35662e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:35662e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:35662e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:35662e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:35662e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:35662e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3566a6f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3566a6f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3566dff0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3566dff0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:35672550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:35672550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:35672550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:35672550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:35672550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:35677f00-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:3567a3e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3567cd0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine is inhibitor of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:3567f1ec-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:35681b5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.076']} DrugCentral uuid:3568448a-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:35686d84-7972-11ec-93d9-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:356896b0-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:3568c0fe-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3568ea66-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.836']} DrugCentral uuid:3569136a-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:35693c96-7972-11ec-93d9-0242ac110002 UniProtKB:Q16853 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3569669e-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35698fc0-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3569b8ce-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3569e1e6-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:356a1026-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:356a3920-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y478 biolink:molecularly_interacts_with DrugCentral:2126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenformin targets Kinase (5'-AMP-activated protein kinase subunit beta-1) DrugCentral uuid:356a5e6e-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:356a879a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) DrugCentral uuid:356aad42-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione targets Enzyme (Prothrombin) DrugCentral uuid:356ad1f0-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:356afb12-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2131 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniprazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:356b2128-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2131 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniprazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:356b46bc-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:356b6b74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:356b9c5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:356b9c5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:356b9c5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:356bde56-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.298']} DrugCentral uuid:356c076e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.883']} DrugCentral uuid:356c305e-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine targets Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:356c5516-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:356c7c62-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:356caad4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:356caad4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:356caad4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:356cec4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:356cec4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:356cec4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:356d2e00-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:356d570e-7972-11ec-93d9-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:356d803a-7972-11ec-93d9-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:356daba0-7972-11ec-93d9-0242ac110002 UniProtKB:Q834R3 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:356dd4d6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:356dfde4-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:356e271a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.456']} DrugCentral uuid:356e5334-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:356e8e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:356e8e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:356e8e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:356e8e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:356e8e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:356eef88-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:356eef88-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:356eef88-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:356f38b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:356f38b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:356f38b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:356f7b9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:356fa4be-7972-11ec-93d9-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:356fcdd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:356ff6ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.745']} DrugCentral uuid:357029c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:357029c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:357029c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:3570641c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentermine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:357088c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentermine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.801']} DrugCentral uuid:3570b32c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:3570dc44-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:35710552-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.784']} DrugCentral uuid:35712e60-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.667']} DrugCentral uuid:3571582c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:35718158-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.616']} DrugCentral uuid:3571aa7a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.684']} DrugCentral uuid:3571d3a6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:3571fe9e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:357227a2-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:357250d8-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:357279f0-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3572a36c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.71']} DrugCentral uuid:3572cca2-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3572f5ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.94']} DrugCentral uuid:35731fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:357348b2-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:357371b6-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:35739ae2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:3573c530-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:3573ee48-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:35741756-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.03']} DrugCentral uuid:35744064-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:357471b0-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:357471b0-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:357471b0-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:3574bc24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:3574bc24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:3574bc24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:3574ff68-7972-11ec-93d9-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:35752880-7972-11ec-93d9-0242ac110002 UniProtKB:O08532 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:35755184-7972-11ec-93d9-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Transporter (L-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:35757a92-7972-11ec-93d9-0242ac110002 UniProtKB:P19111 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Enzyme (Intestinal alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:3575a698-7972-11ec-93d9-0242ac110002 UniProtKB:Q6DWJ6 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine is agonist of GPCR (Probable G-protein coupled receptor 139) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3575d028-7972-11ec-93d9-0242ac110002 UniProtKB:P09923 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Enzyme (Intestinal-type alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3575f9b8-7972-11ec-93d9-0242ac110002 UniProtKB:P98170 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Unclassified (E3 ubiquitin-protein ligase XIAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:357622da-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:35764c38-7972-11ec-93d9-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:3576753c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16647 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Prostacyclin synthase) DrugCentral uuid:35769a12-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:3576c3e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8SPQ9 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3576f0e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3576f0e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:35772608-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:35774f34-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:35777b76-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3577a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3577cde2-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:3577f6f0-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3578206c-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3578521c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3578521c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3578521c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:35789bfa-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:35789bfa-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:35789bfa-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3578e506-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3578e506-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3578e506-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:35792660-7972-11ec-93d9-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:357952ac-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:35797c46-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:3579a0f4-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3579c9f8-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:3579f39c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:357a1980-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:357a4298-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:357a6c00-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:357a9522-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.166']} DrugCentral uuid:357abe30-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:357ae748-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:357b1132-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:357b3a5e-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:357b639e-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:357b8cc0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:357bb7d6-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:357be0f8-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:357c0a2e-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:357c2efa-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:357c54a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:357c7a0e-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:357c9ee4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:357cc7fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:357cee4e-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:357d1784-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:357d3c64-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:357d6130-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:357d9308-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:357d9308-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:357d9308-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:357dd46c-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phloroglucinol targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:357e0158-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:357e0158-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:357e3eca-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:357e3eca-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:357e3eca-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:357e8010-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:357ea946-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.37']} DrugCentral uuid:357ed5ba-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:357efee6-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:357f27ea-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.17']} DrugCentral uuid:357f524c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:357f7c9a-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.17']} DrugCentral uuid:357fa5a8-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:357fced4-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:357ff846-7972-11ec-93d9-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:35802140-7972-11ec-93d9-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:35804a30-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:35807348-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:35809df0-7972-11ec-93d9-0242ac110002 UniProtKB:P36196 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3580c6fe-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3580efe4-7972-11ec-93d9-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:358118f2-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:35814278-7972-11ec-93d9-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3581a4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:35828606-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3582af0a-7972-11ec-93d9-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin is blocker of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3582d822-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin is blocker of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:35830216-7972-11ec-93d9-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin targets Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:35832b10-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:35834fc8-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:3583748a-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:35839e10-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3583c728-7972-11ec-93d9-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3583f018-7972-11ec-93d9-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:358429a2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:358429a2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:358429a2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:358429a2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:358429a2-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:3584842e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:3584ad46-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:3584d6c2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:3584ffbc-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:358528b6-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:358551ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilsicainide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:35857c44-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilsicainide is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.377']} DrugCentral uuid:3585a520-7972-11ec-93d9-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interleukin-5) DrugCentral uuid:3585c9c4-7972-11ec-93d9-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interferon gamma) DrugCentral uuid:3585ee9a-7972-11ec-93d9-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:35861a28-7972-11ec-93d9-0242ac110002 UniProtKB:P60568 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interleukin-2) DrugCentral uuid:35863ef4-7972-11ec-93d9-0242ac110002 UniProtKB:P48454 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform) DrugCentral uuid:358663ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q62658 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:35868cc4-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3586b65e-7972-11ec-93d9-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3586df4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTS6 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets Enzyme (Histone-lysine N-methyltransferase SETD7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3587085c-7972-11ec-93d9-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:35873552-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:35873552-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:35876ae0-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:35879402-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.862']} DrugCentral uuid:3587bd1a-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.798']} DrugCentral uuid:3587e830-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.842']} DrugCentral uuid:35881170-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:35883a6a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:3588635a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.63']} DrugCentral uuid:35888cea-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.559']} DrugCentral uuid:3588b5f8-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.058']} DrugCentral uuid:3588df06-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.149']} DrugCentral uuid:35890828-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.301']} DrugCentral uuid:35893186-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.704']} DrugCentral uuid:35895b2a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:35898636-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:3589b0d4-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:3589da32-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:358a0336-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.709']} DrugCentral uuid:358a2c3a-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:358a55b6-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.424']} DrugCentral uuid:358a7eba-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:358aa7dc-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:358ad0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:358afa34-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:358b231a-7972-11ec-93d9-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:358b53bc-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:358b53bc-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:358b53bc-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:358b95b6-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:358bbee2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:358be7dc-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:358c10ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:358c3b06-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:358c6446-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:358c8d4a-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:358cb644-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:358cdfe8-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:358d181e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:358d181e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:358d181e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:358d181e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:358d181e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:358d74a8-7972-11ec-93d9-0242ac110002 UniProtKB:O94782 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Enzyme (Ubiquitin carboxyl-terminal hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:358d9db6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EQ60 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:358dc6ce-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:358defdc-7972-11ec-93d9-0242ac110002 UniProtKB:O54898 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:358e1958-7972-11ec-93d9-0242ac110002 UniProtKB:O60706 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil targets Ion channel (ATP-binding cassette sub-family C member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:358e422a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:358e6af2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:358e6af2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:358ea0a8-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is partial agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:358ec9d4-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is partial agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:358ef42c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:358f1d58-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:358f486e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:358f719a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:358f9aa8-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.78']} DrugCentral uuid:358fc3b6-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:358fed8c-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.209']} DrugCentral uuid:359016a4-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:35903fd0-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:35907568-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:35907568-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:35907568-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:35907568-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3590cb6c-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:3590cb6c-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:3590cb6c-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:35910e4c-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.943']} DrugCentral uuid:35913750-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:35916054-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:35918962-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.455']} DrugCentral uuid:3591b2fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3591dc14-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3592050e-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.879']} DrugCentral uuid:35922e08-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:359257d4-7972-11ec-93d9-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:359280d8-7972-11ec-93d9-0242ac110002 UniProtKB:P37238 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3592a9e6-7972-11ec-93d9-0242ac110002 UniProtKB:O88275 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3592d308-7972-11ec-93d9-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:3592fe50-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:35932768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3593506c-7972-11ec-93d9-0242ac110002 UniProtKB:B0K020 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:359379ca-7972-11ec-93d9-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:3593a2ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5K1 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3593cbd2-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:3593f4fe-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.87']} DrugCentral uuid:35941ec0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:35944904-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:35947208-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.461']} DrugCentral uuid:35949c74-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.351']} DrugCentral uuid:3594c654-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.992']} DrugCentral uuid:3594ef80-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.256']} DrugCentral uuid:359518ac-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:359541e2-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:35956b7c-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:359594b2-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.105']} DrugCentral uuid:3595bdde-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.799']} DrugCentral uuid:3595e7aa-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.939']} DrugCentral uuid:35961144-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:35963a70-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.189']} DrugCentral uuid:359663a6-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:35968e4e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:3596ba90-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.848']} DrugCentral uuid:3596e592-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:35970eb4-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.429']} DrugCentral uuid:35973830-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:3597612a-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:35978a2e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:3597b350-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:3597dd1c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:3598063e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:35982f60-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:35985ada-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3598846a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.324']} DrugCentral uuid:3598ad8c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.644']} DrugCentral uuid:3598d6ae-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:35990034-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.602']} DrugCentral uuid:35992956-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:35995282-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:35997bae-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3599a52a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:3599ce56-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:3599f76e-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:359a2464-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:359a2464-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:359a5eca-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:359a5eca-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:359a5eca-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:359a9dc2-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:359a9dc2-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:359ad170-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:359ad170-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:359b00a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:359b2544-7972-11ec-93d9-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:359b4e3e-7972-11ec-93d9-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:359b8f52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:359b8f52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:359b8f52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:359b8f52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:359b8f52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:359b8f52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:359b8f52-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:359bf438-7972-11ec-93d9-0242ac110002 UniProtKB:O18276 biolink:molecularly_interacts_with DrugCentral:2188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperazine targets Ion channel (Gamma-aminobutyric acid receptor subunit beta) DrugCentral uuid:359c19d6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipotiazine palmitate is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:359c42e4-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipotiazine palmitate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.553']} DrugCentral uuid:359c6c10-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2199 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirbuterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:359c90d2-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:359cba9e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:359ce3ac-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:359d0cba-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:359d362c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:359d5f4e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:359d887a-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:359db214-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:359ddbcc-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:359e04d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:359e2de8-7972-11ec-93d9-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:359e570a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:359e80c2-7972-11ec-93d9-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:359eb916-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:359eb916-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:359eb916-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:359eb916-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:359eb916-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:359f2374-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:359f2374-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:359f2374-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:359f2374-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:359f2374-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:359f7dd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piretanide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:359fa7d6-7972-11ec-93d9-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:2201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piretanide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:359fd148-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:359ffa60-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:35a02382-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:35a04cfe-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:35a07616-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:35a09f38-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:35a0c850-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:35a0f1c2-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:35a11ada-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:35a143de-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:35a16d14-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:35a198ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:35a1c19c-7972-11ec-93d9-0242ac110002 UniProtKB:P28347 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:35a1eab4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:35a213cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q15562 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:35a23d52-7972-11ec-93d9-0242ac110002 UniProtKB:Q99594 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:35a26674-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:35a28f64-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirmenol targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:35a2b494-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:35a2dda2-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:35a306a6-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:35a33478-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:35a33478-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:35a370dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:35a370dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:35a3a62e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirprofen targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:35a3cadc-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirprofen targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:35a3f016-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.168']} DrugCentral uuid:35a41a0a-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:35a44318-7972-11ec-93d9-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:35a46d2a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:35a4969c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:35a4bfa0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:35a4e8cc-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:35a511d0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:35a53c82-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:35a565a4-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:35a58eb2-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polythiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['9.09']} DrugCentral uuid:35a5b7ca-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralidoxime is activator of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.59']} DrugCentral uuid:35a5e13c-7972-11ec-93d9-0242ac110002 UniProtKB:O08725 biolink:molecularly_interacts_with DrugCentral:2232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralmorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:35a60a4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q92847 biolink:molecularly_interacts_with DrugCentral:2232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralmorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) DrugCentral uuid:35a62f16-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:35a6582e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:35a6818c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.121']} DrugCentral uuid:35a6aaa4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:35a6d3bc-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:35a6fe0a-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.925']} DrugCentral uuid:35a7283a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:35a75152-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.668']} DrugCentral uuid:35a77a38-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:35a7a3b4-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.455']} DrugCentral uuid:35a7cccc-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:35a7f5da-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.282']} DrugCentral uuid:35a81f10-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:35a848a0-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:35a871cc-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:35a89aee-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:35a8c802-7972-11ec-93d9-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:35a8c802-7972-11ec-93d9-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:35a90240-7972-11ec-93d9-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:35a90240-7972-11ec-93d9-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:35a93b52-7972-11ec-93d9-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:35a93b52-7972-11ec-93d9-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:35a970f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:35a999f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:35a9c2e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:35a9ec0a-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:35aa1694-7972-11ec-93d9-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:35aa4042-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Nuclear other (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:35aa693c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:35aa9236-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:35aabd60-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:35aae772-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:35ab1076-7972-11ec-93d9-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:35ab3966-7972-11ec-93d9-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:35ab6ae4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:35ab6ae4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:35ab6ae4-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:35aba496-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:35abcd9a-7972-11ec-93d9-0242ac110002 UniProtKB:P08515 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel targets Enzyme (Glutathione S-transferase class-mu 26 kDa isozyme) DrugCentral uuid:35abf2d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q95US7 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel is blocker of Ion channel (High voltage-activated calcium channel beta subunit CavB1) DrugCentral uuid:35ac17aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q962H3 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel is blocker of Ion channel (High voltage-activated calcium channel beta subunit CavB2) DrugCentral uuid:35ac3c76-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednicarbate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:35ac6156-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:35ac8c44-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Cytosolic other (Annexin A1) DrugCentral uuid:35acb12e-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:35acda46-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:35ad035e-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:35ad2d02-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:35ad5610-7972-11ec-93d9-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:35ad7f00-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:35ada822-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:35add194-7972-11ec-93d9-0242ac110002 UniProtKB:P15104 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Enzyme (Glutamine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:35adfaa2-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:35ae2392-7972-11ec-93d9-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:35ae4d68-7972-11ec-93d9-0242ac110002 UniProtKB:P78536 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Unclassified (Disintegrin and metalloproteinase domain-containing protein 17) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:35ae76da-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:35ae9fe8-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:35aec626-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.28']} DrugCentral uuid:35aeeffc-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:35af1914-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:35af4240-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:35af6bda-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:35af959c-7972-11ec-93d9-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:35afbfd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:35afe8ee-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:35b01206-7972-11ec-93d9-0242ac110002 UniProtKB:P15104 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Enzyme (Glutamine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:35b03c9a-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:35b065b2-7972-11ec-93d9-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:35b08efc-7972-11ec-93d9-0242ac110002 UniProtKB:P78536 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Unclassified (Disintegrin and metalloproteinase domain-containing protein 17) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:35b0b800-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:35b0e1c2-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.772']} DrugCentral uuid:35b10ada-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:35b133ca-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone targets Cytosolic other (Annexin A1) DrugCentral uuid:35b158d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.801']} DrugCentral uuid:35b18208-7972-11ec-93d9-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:35b1ab34-7972-11ec-93d9-0242ac110002 UniProtKB:O77773 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin targets Ion channel (Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:35b1d456-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:35b1fe90-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:35b229f6-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:35b25318-7972-11ec-93d9-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:35b27c08-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenalterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:35b2a6a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenalterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.97']} DrugCentral uuid:35b2d784-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:35b2d784-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:35b2d784-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:35b32054-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:35b32054-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:35b32054-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:35b36212-7972-11ec-93d9-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:35b38b16-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:35b3b424-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:35b3de54-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.194']} DrugCentral uuid:35b40744-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:35b43048-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.799']} DrugCentral uuid:35b46108-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:35b46108-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:35b46108-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:35b4a366-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.668']} DrugCentral uuid:35b4cc56-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.075']} DrugCentral uuid:35b4f546-7972-11ec-93d9-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:35b51ba2-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:35b54488-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:35b56d82-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.739']} DrugCentral uuid:35b59686-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:35b5c250-7972-11ec-93d9-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:35b5e6fe-7972-11ec-93d9-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:35b61124-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:35b63a32-7972-11ec-93d9-0242ac110002 UniProtKB:P35869 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transcription factor (Aryl hydrocarbon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:35b663d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:35b68cda-7972-11ec-93d9-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:35b6b5e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Unclassified (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:35b6e72a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:35b6e72a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:35b6e72a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:35b720f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:35b749ea-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:35b7738e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:35b79cba-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:35b7c5e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:35b7eeea-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 8) DrugCentral uuid:35b8142e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 11) DrugCentral uuid:35b838fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:35b86212-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:35b88b20-7972-11ec-93d9-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:35b8b4e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAW7 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (UDP-glucuronosyltransferase 1-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.02']} DrugCentral uuid:35b8de04-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:35b906fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.686']} DrugCentral uuid:35b9300c-7972-11ec-93d9-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35b95b22-7972-11ec-93d9-0242ac110002 UniProtKB:O95477 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol is inhibitor of Transporter (ATP-binding cassette sub-family A member 1) DrugCentral uuid:35b98214-7972-11ec-93d9-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:35b9abe0-7972-11ec-93d9-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:35b9d4bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.86']} DrugCentral uuid:35b9ffaa-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.812']} DrugCentral uuid:35ba28ae-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:35ba51bc-7972-11ec-93d9-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 1) DrugCentral uuid:35ba7656-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:35ba9bb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBC3 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 3B) DrugCentral uuid:35bac070-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb0cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:35bb92e8-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.569']} DrugCentral uuid:35bbbc64-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.529']} DrugCentral uuid:35bbe568-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:35bc0a16-7972-11ec-93d9-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.222']} DrugCentral uuid:35bc3ac2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:35bc3ac2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:35bc3ac2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:35bc7cbc-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:35bca5c0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:35bccef6-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.712']} DrugCentral uuid:35bcf976-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:35bd22c0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.764']} DrugCentral uuid:35bd4cdc-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.201']} DrugCentral uuid:35bd7608-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:35bd9f8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:35bdc8ce-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.207']} DrugCentral uuid:35bdf1e6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.402']} DrugCentral uuid:35be1afe-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.229']} DrugCentral uuid:35be44ca-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:35be6dec-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:35be970e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:35bec044-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:35beea2e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.622']} DrugCentral uuid:35bf135a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.324']} DrugCentral uuid:35bf3c86-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.611']} DrugCentral uuid:35bf6620-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.723']} DrugCentral uuid:35bf8f42-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.613']} DrugCentral uuid:35bfb9a4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.956']} DrugCentral uuid:35bfe2bc-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.493']} DrugCentral uuid:35c00c60-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:35c03582-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.801']} DrugCentral uuid:35c05f30-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:35c08852-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:35c0b21e-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:35c0db2c-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:35c10444-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:35c12d70-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:35c15804-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.245']} DrugCentral uuid:35c18112-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:35c1a9f8-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:35c1d374-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.919']} DrugCentral uuid:35c1fcb4-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.381']} DrugCentral uuid:35c225d6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:35c24eda-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:35c27964-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35c2a29a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.337']} DrugCentral uuid:35c2cba8-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:35c2f4b6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.907']} DrugCentral uuid:35c31e64-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:35c3477c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:35c370a8-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:35c3b126-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35c3b126-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35c3b126-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35c3b126-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35c3b126-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35c3b126-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35c3b126-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35c42a7a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:35c42a7a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:35c42a7a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c4a68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c5c128-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35c6a890-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.174']} DrugCentral uuid:35c6d216-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:35c6fb4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:35c72464-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:35c74d90-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:35c77702-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:35c79bce-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:35c7c590-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['9.876']} DrugCentral uuid:35c7f114-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:35c81a86-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.94']} DrugCentral uuid:35c843b2-7972-11ec-93d9-0242ac110002 UniProtKB:P35610 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Sterol O-acyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:35c86cca-7972-11ec-93d9-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:35c89646-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:35c8bf40-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:35c8e844-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.441']} DrugCentral uuid:35c91170-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:35c93b78-7972-11ec-93d9-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:35c9647c-7972-11ec-93d9-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:35c98db2-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:35c9b7ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:35c9e6ea-7972-11ec-93d9-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:35c9e6ea-7972-11ec-93d9-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:35ca2010-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:35ca2010-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:35ca556c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:35ca7ede-7972-11ec-93d9-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:35caa800-7972-11ec-93d9-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:35cad118-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:35cafa26-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is blocker of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:35cb23a2-7972-11ec-93d9-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:35cb4cba-7972-11ec-93d9-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:2281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proglumide targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.6']} DrugCentral uuid:35cb75d2-7972-11ec-93d9-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:2281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proglumide is antagonist of GPCR (Gastrin/cholecystokinin type B receptor) DrugCentral uuid:35cb9bd4-7972-11ec-93d9-0242ac110002 UniProtKB:Q0IJY2 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:35cbc096-7972-11ec-93d9-0242ac110002 UniProtKB:O02604 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:35cbe576-7972-11ec-93d9-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:35cc0a4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:35cc33a0-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.909']} DrugCentral uuid:35cc5ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.704']} DrugCentral uuid:35cc860c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:35ccaf38-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.943']} DrugCentral uuid:35ccd8b4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:35cd01d6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:35cd2b02-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.529']} DrugCentral uuid:35cd54c4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:35cd812e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.656']} DrugCentral uuid:35cdabc2-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:35cdd4ee-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:35cdfe1a-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.226']} DrugCentral uuid:35ce27be-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:35ce50e0-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.799']} DrugCentral uuid:35ce79ee-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:35cea306-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.551']} DrugCentral uuid:35cecc6e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.825']} DrugCentral uuid:35cef590-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.412']} DrugCentral uuid:35cf1ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.056']} DrugCentral uuid:35cf4982-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:35cf72b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:35cf9bd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.796']} DrugCentral uuid:35cfc4ca-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:35cfee50-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:35d01754-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.427']} DrugCentral uuid:35d0408a-7972-11ec-93d9-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:35d06998-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:35d092ec-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:35d0bc04-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.344']} DrugCentral uuid:35d0e526-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.806']} DrugCentral uuid:35d10e3e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:35d13ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:35d163e8-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:35d18de6-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:35d1bb4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:35d1bb4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:35d1ff9c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:35d1ff9c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:35d1ff9c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:35d1ff9c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:35d1ff9c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:35d26130-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:35d26130-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:35d26130-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:35d2a294-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:35d2cb8e-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promegestone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:35d2f64a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promegestone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:35d320c0-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:35d349ce-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.609']} DrugCentral uuid:35d372f0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.592']} DrugCentral uuid:35d39d20-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:35d3c638-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:35d3ef50-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:35d41868-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:35d441ee-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:35d46b1a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:35d49446-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.188']} DrugCentral uuid:35d4bd5e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.948']} DrugCentral uuid:35d4e8a6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:35d50d5e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:35d5368a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:35d5602e-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:35d58964-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.941']} DrugCentral uuid:35d5b286-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.823']} DrugCentral uuid:35d5db9e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.479']} DrugCentral uuid:35d6051a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:35d62e32-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.382']} DrugCentral uuid:35d6574a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.975']} DrugCentral uuid:35d6806c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:35d6abd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.292']} DrugCentral uuid:35d6d4ea-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.452']} DrugCentral uuid:35d6fdf8-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:35d72724-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:35d750f0-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:35d77a08-7972-11ec-93d9-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:35d7a316-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:35d7cc56-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:35d7f578-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:35d81e9a-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:35d847b2-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:35d87a8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:35d87a8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:35d87a8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:35d8bcb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:35d8e6e0-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:35d910e8-7972-11ec-93d9-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.3']} DrugCentral uuid:35d93a14-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP23 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Cytosolic other (Calmodulin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:35d963b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pronetalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:35d98d02-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:35d9b6a6-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:35d9dfdc-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:35da08cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:35da2d7a-7972-11ec-93d9-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:35da5322-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:35da77e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:35da9c9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:35dac5be-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:35daef80-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['7.056']} DrugCentral uuid:35db1884-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.524']} DrugCentral uuid:35db4188-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.029']} DrugCentral uuid:35db6aaa-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.728']} DrugCentral uuid:35db944e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:35dbbd70-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:35dbe6a6-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:35dc0fb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:35dc39d0-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.498']} DrugCentral uuid:35dc62fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:35dc8c1e-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.337']} DrugCentral uuid:35dcb5ea-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:35dce006-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.483']} DrugCentral uuid:35dd0928-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:35dd3236-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:35dd5bb2-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:35dd84b6-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:35ddadb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:35ddd6b4-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.849']} DrugCentral uuid:35de0170-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:35de2a7e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:35de53dc-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.602']} DrugCentral uuid:35de80b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:35de80b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:35deb660-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:35dee0ae-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:35df09e4-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:35df334c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.2']} DrugCentral uuid:35df5d04-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:35df8626-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:35dfaf3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:35dfde00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:35dfde00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:35dfde00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:35e01f78-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propentofylline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:35e04872-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(1A) dopamine receptor) DrugCentral uuid:35e06d98-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(2) dopamine receptor) DrugCentral uuid:35e0934a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:35e0b80c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (5-hydroxytryptamine receptor 2C) DrugCentral uuid:35e0dce2-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:35e101f4-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:35e126a2-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:35e14b50-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:35e16fea-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:35e195f6-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:35e1bacc-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(4) dopamine receptor) DrugCentral uuid:35e1df7a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:35e20446-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiram is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:35e228ea-7972-11ec-93d9-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.284']} DrugCentral uuid:35e25266-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.417']} DrugCentral uuid:35e27b92-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.031']} DrugCentral uuid:35e2a4a0-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:35e2ce26-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.218']} DrugCentral uuid:35e2f73e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.005']} DrugCentral uuid:35e32024-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:35e34928-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:35e3734e-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.119']} DrugCentral uuid:35e39c3e-7972-11ec-93d9-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:35e3c556-7972-11ec-93d9-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:35e3f620-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:35e3f620-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:35e3f620-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:35e440a8-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:35e440a8-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:35e440a8-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e4bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:35e5a34e-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:35e5a34e-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:35e5a34e-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:35e5e502-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.919']} DrugCentral uuid:35e60e10-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:35e637be-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:35e660a4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.913']} DrugCentral uuid:35e68b42-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:35e6b45a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.662']} DrugCentral uuid:35e6dd7c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:35e7069e-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:35e731c8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.699']} DrugCentral uuid:35e75ae0-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:35e78402-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.197']} DrugCentral uuid:35e7ad7e-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:35e7d768-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:35e8006c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.319']} DrugCentral uuid:35e82984-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:35e852e2-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:35e87d08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.297']} DrugCentral uuid:35e8a62a-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:35e8cf60-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.671']} DrugCentral uuid:35e8fa9e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:35e923c0-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:35e94cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.01']} DrugCentral uuid:35e9760e-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.05']} DrugCentral uuid:35e99fbc-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:35e9c8ca-7972-11ec-93d9-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:35e9f1d8-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.76']} DrugCentral uuid:35ea2324-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:35ea2324-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:35ea2324-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:35ea655a-7972-11ec-93d9-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:35ea8e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:35eab794-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:35eae1f6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:35eb0b22-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:35eb3430-7972-11ec-93d9-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil is inhibitor of Enzyme (Thyroid peroxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:35eb5db6-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:35eb86d8-7972-11ec-93d9-0242ac110002 UniProtKB:P49895 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil is inhibitor of Enzyme (Type I iodothyronine deiodinase) DrugCentral uuid:35ebaba4-7972-11ec-93d9-0242ac110002 UniProtKB:P59533 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil targets GPCR (Taste receptor type 2 member 38) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:35ebd4b2-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:2309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propyphenazone is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.481']} DrugCentral uuid:35ebfde8-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:35ec22b4-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:35ec4bcc-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:35ec4bcc-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:35ec80e2-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proscillaridin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.056']} DrugCentral uuid:35ecabc6-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proscillaridin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:35ecd07e-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protionamide targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:35ecf9aa-7972-11ec-93d9-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin is agonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:35ed22cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:35ed4cb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R297 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Protein Trhr2; Thyrotropin releasing hormone receptor 2; Thyrotropin-releasing hormone receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:35ed75c4-7972-11ec-93d9-0242ac110002 UniProtKB:P21761 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:35ed9eb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERT1 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:35edc858-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protokylol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:35eded10-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.928']} DrugCentral uuid:35ee175e-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:35ee408a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:35ee6bf0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:35ee94fe-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:35eebe16-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:35eee724-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:35ef10f0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:35ef39f4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:35ef630c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:35ef8c10-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:35efb58c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:35efde7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:35f007a8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:35f030b6-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:35f05758-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:35f07c2e-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:35f0a0dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:35f0c58a-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:35f0ef4c-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:35f11846-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPB6 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cyclopropane mycolic acid synthase 1) DrugCentral uuid:35f13d08-7972-11ec-93d9-0242ac110002 UniProtKB:Q50575 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Amidase; Nicotinamidase; Nicotinamidase/pyrazinamidase; Pyrazinamidase; Pyrazinamidase/nicotinamidase; Pyrazinamidase/nicotinamidase PncA) DrugCentral uuid:35f161a2-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:35f18b28-7972-11ec-93d9-0242ac110002 UniProtKB:P95029 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide is inhibitor of Enzyme (3-oxoacyl-ACP synthase; Fatty acid synthase Fas; Probable fatty acid synthase Fas (Fatty acid synthetase)) DrugCentral uuid:35f1aff4-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:35f1d916-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:35f20242-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:35f22d30-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:35f2563e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.952']} DrugCentral uuid:35f28032-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:35f2aaa8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:35f2d3b6-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:35f2fcb0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:35f325dc-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.751']} DrugCentral uuid:35f34f4e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.228']} DrugCentral uuid:35f3787a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:35f3a188-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:35f3cab4-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:35f3f656-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:35f41f6e-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:35f4485e-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:35f47162-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.721']} DrugCentral uuid:35f49b10-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:35f4c428-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.288']} DrugCentral uuid:35f4ed40-7972-11ec-93d9-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.409']} DrugCentral uuid:35f5164e-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:35f53fd4-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:35f568d8-7972-11ec-93d9-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:35f591f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:35f5bbbc-7972-11ec-93d9-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.602']} DrugCentral uuid:35f5e4d4-7972-11ec-93d9-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:35f60de2-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:35f63704-7972-11ec-93d9-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:35f660b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.009']} DrugCentral uuid:35f68aec-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:35f6b3f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q27783 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:35f6dd08-7972-11ec-93d9-0242ac110002 UniProtKB:O08966 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:35f7071a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K0H1 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Unclassified (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:35f7301e-7972-11ec-93d9-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:35f7592c-7972-11ec-93d9-0242ac110002 UniProtKB:P06865 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Beta-hexosaminidase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:35f7821c-7972-11ec-93d9-0242ac110002 UniProtKB:P07686 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Beta-hexosaminidase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:35f7abfc-7972-11ec-93d9-0242ac110002 UniProtKB:Q3V050 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Unclassified (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:35f7d514-7972-11ec-93d9-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:35f7fe4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8I1R6 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:35f82820-7972-11ec-93d9-0242ac110002 UniProtKB:F1KRD8 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Unclassified (Fumarate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:35f851d8-7972-11ec-93d9-0242ac110002 UniProtKB:O15056 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Synaptojanin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:35f87adc-7972-11ec-93d9-0242ac110002 UniProtKB:O43426 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Synaptojanin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:35f8a3f4-7972-11ec-93d9-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:35f8d4fa-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:35f8d4fa-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:35f8d4fa-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:35f91de8-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:35f91de8-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:35f91de8-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:35f967ee-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:35f967ee-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:35f967ee-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:35f9aa92-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:35f9d49a-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:35f9fe5c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:35fa2760-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.483']} DrugCentral uuid:35fa5046-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:35fa7954-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.016']} DrugCentral uuid:35faa2c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:35facbb6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:35faf49c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:35fb1d96-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.131']} DrugCentral uuid:35fb4834-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:35fb712e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:35fb9a14-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:35fbc32c-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.512']} DrugCentral uuid:35fbecd0-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.027']} DrugCentral uuid:35fc15d4-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.127']} DrugCentral uuid:35fc3ee2-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:35fc67e6-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:35fc9176-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:35fcba5c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:35fce360-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.037']} DrugCentral uuid:35fd0d72-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.795']} DrugCentral uuid:35fd36d0-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.266']} DrugCentral uuid:35fd5fca-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.524']} DrugCentral uuid:35fd88ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:35fdb1fa-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:35fddbe4-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:35fe04f2-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.241']} DrugCentral uuid:35fe2df6-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:35fe5768-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:35fe8080-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:35fea97a-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.506']} DrugCentral uuid:35fed29c-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:35fefd4e-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:35ff2670-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.866']} DrugCentral uuid:35ff4f88-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.936']} DrugCentral uuid:35ff7a12-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.06']} DrugCentral uuid:35ffa41a-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:35ffcd32-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:35fff65e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:36001ff8-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3600491a-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3600720a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:36009b0e-7972-11ec-93d9-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3600c688-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:3600f180-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.542']} DrugCentral uuid:36011a98-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:360143b0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.079']} DrugCentral uuid:36016d40-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:36019662-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.459']} DrugCentral uuid:3601bf7a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.445']} DrugCentral uuid:3601e9b4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.465']} DrugCentral uuid:360212ea-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.575']} DrugCentral uuid:36023c0c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.558']} DrugCentral uuid:36026542-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:36028f0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.481']} DrugCentral uuid:3602b7fe-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:3602e12a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.994']} DrugCentral uuid:36030a60-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.574']} DrugCentral uuid:36033404-7972-11ec-93d9-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:36035d12-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:36038634-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:3603af6a-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:3603d8dc-7972-11ec-93d9-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:360405dc-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:360405dc-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:360442a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:360442a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:360442a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:360491f0-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:360491f0-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:360491f0-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:360491f0-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3604df20-7972-11ec-93d9-0242ac110002 UniProtKB:P00592 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Phospholipase A2 group 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:36050a2c-7972-11ec-93d9-0242ac110002 UniProtKB:P04055 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Phospholipase A2 group 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:360564cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:36063578-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:36063578-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:36063578-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:36067b50-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:36067b50-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3606b818-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3606b818-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3606b818-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3606fa4e-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.08']} DrugCentral uuid:36072384-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.397']} DrugCentral uuid:36074cb0-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:360771d6-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinethazone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:36079698-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quingestanol acetate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:3607bc72-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3607e558-7972-11ec-93d9-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:36080b50-7972-11ec-93d9-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:360831ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:3608566e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:36087b30-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:3608a4d4-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3608cdec-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.125']} DrugCentral uuid:3608f6fa-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:36091fea-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:36094a88-7972-11ec-93d9-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3609738c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.106']} DrugCentral uuid:36099cae-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3609c5bc-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3609f082-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.061']} DrugCentral uuid:360a199a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:360a4a5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:360a4a5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:360a4a5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:360a8c4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:360ab562-7972-11ec-93d9-0242ac110002 UniProtKB:Q63881 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:360ade5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:360b0756-7972-11ec-93d9-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:360b30e6-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is inhibitor of Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:360b59fe-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:360b8406-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.102']} DrugCentral uuid:360bad1e-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.119']} DrugCentral uuid:360bd74e-7972-11ec-93d9-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:360bfc24-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:360c2532-7972-11ec-93d9-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:360c52f0-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:360c52f0-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:360c8306-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:360cac1e-7972-11ec-93d9-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:360cd54a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:360cfeb2-7972-11ec-93d9-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:360d27de-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:360d510a-7972-11ec-93d9-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:360d7a18-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.321']} DrugCentral uuid:360da3e4-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:360dcd10-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.408']} DrugCentral uuid:360df63c-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.926']} DrugCentral uuid:360e1ff4-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.205']} DrugCentral uuid:360e4916-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:360e7224-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:360e9b32-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:360ec4b8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.553']} DrugCentral uuid:360eef1a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:360f185a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:360f417c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:360f6c56-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:360f9690-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:360fbfb2-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:360fe8c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.538']} DrugCentral uuid:3610121e-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.523']} DrugCentral uuid:36103b40-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.971']} DrugCentral uuid:36106458-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:36108d7a-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:3610b700-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.321']} DrugCentral uuid:3610e018-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.193']} DrugCentral uuid:3611094e-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:36113414-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:36115da4-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:361186a8-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:3611afc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3611d928-7972-11ec-93d9-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3612022c-7972-11ec-93d9-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:36122bbc-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.436']} DrugCentral uuid:361254ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:36127e50-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.876']} DrugCentral uuid:3612a75e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13393 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Phospholipase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3612d076-7972-11ec-93d9-0242ac110002 UniProtKB:O14939 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Phospholipase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3612f970-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.827']} DrugCentral uuid:361323be-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.073']} DrugCentral uuid:36134cd6-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.625']} DrugCentral uuid:361375da-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3613a046-7972-11ec-93d9-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:3613c968-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:3613f294-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:36141bc0-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:361448c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.73']} DrugCentral uuid:361448c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.73']} DrugCentral uuid:36147e3a-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3614a766-7972-11ec-93d9-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.66']} DrugCentral uuid:3614d07e-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3614fc16-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir is inhibitor of Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:3615254c-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:36154e46-7972-11ec-93d9-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:361577d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3615a184-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3615ca92-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.678']} DrugCentral uuid:3615f396-7972-11ec-93d9-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:36161ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:361645e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:36166ed4-7972-11ec-93d9-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.244']} DrugCentral uuid:361697ec-7972-11ec-93d9-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3616c230-7972-11ec-93d9-0242ac110002 UniProtKB:P45352 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3616eb48-7972-11ec-93d9-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3617144c-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:36173d50-7972-11ec-93d9-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:361766cc-7972-11ec-93d9-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:361790ca-7972-11ec-93d9-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3617b9f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:3617e386-7972-11ec-93d9-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is inverse agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:36180cb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:361835de-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XKD3 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is antagonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:36185f78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is antagonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:36188a66-7972-11ec-93d9-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:2355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramelteon is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.9']} DrugCentral uuid:3618b3e2-7972-11ec-93d9-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:2355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramelteon is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.39']} DrugCentral uuid:3618dd18-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramipril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.342']} DrugCentral uuid:36190658-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramipril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:36192fd4-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:3619590a-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.86']} DrugCentral uuid:36198218-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3619ab26-7972-11ec-93d9-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:3619d4a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:3619fdb0-7972-11ec-93d9-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:361a26f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:361a4ff4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:361a7bbe-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:361aa094-7972-11ec-93d9-0242ac110002 UniProtKB:Q5YLN7 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Unclassified (Voltage-gated sodium channel Nav1.5 cardiac isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:361ac98e-7972-11ec-93d9-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rebamipide is agonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:361af44a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:361b1d76-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:361b468e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:361b6fb0-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:361b9a26-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:361bc32a-7972-11ec-93d9-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.194']} DrugCentral uuid:361bec2e-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:361c153c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:361c3fb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:361c6ca8-7972-11ec-93d9-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:361c6ca8-7972-11ec-93d9-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:361ca5b0-7972-11ec-93d9-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.387']} DrugCentral uuid:361ca5b0-7972-11ec-93d9-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.387']} DrugCentral uuid:361cdb52-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson is agonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:361d044c-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.398']} DrugCentral uuid:361d2d64-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:361d565e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:361d7fda-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:361da910-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:361dcddc-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:361df6f4-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:361e2156-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:361e4af0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:361e73fe-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:361e9d8e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:361ec6ba-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:361eefe6-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:361f18fe-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:361f423e-7972-11ec-93d9-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:361f6b60-7972-11ec-93d9-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:361fa4ae-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:361fa4ae-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:361fa4ae-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:361fa4ae-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:361fa4ae-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3620014c-7972-11ec-93d9-0242ac110002 UniProtKB:Q09428 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Ion channel (ATP-binding cassette sub-family C member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:36202a64-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Transporter (Solute carrier organic anion transporter family member 1B1) DrugCentral uuid:36204f30-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:36207d8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:36207d8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:3620b6a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:3620b6a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:3620ebe8-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reproterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:36211122-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rescinnamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:362135e4-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:36215ef2-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.415']} DrugCentral uuid:3621880a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.232']} DrugCentral uuid:3621b23a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3621db52-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.737']} DrugCentral uuid:3622047e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:36222da0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:362256fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:36228002-7972-11ec-93d9-0242ac110002 UniProtKB:Q27963 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3622a910-7972-11ec-93d9-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3622d1f6-7972-11ec-93d9-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:3623032e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3623032e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3623032e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:362345dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BRU6 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:36236ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.836']} DrugCentral uuid:36239b7c-7972-11ec-93d9-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:2372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol acetate targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3623c4a8-7972-11ec-93d9-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:2372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol acetate targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3623edd4-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:362416ce-7972-11ec-93d9-0242ac110002 UniProtKB:P55263 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Kinase (Adenosine kinase) DrugCentral uuid:36243bf4-7972-11ec-93d9-0242ac110002 UniProtKB:P22413 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (Ectonucleotide pyrophosphatase/phosphodiesterase family member 1) DrugCentral uuid:362460ac-7972-11ec-93d9-0242ac110002 UniProtKB:P49902 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (Cytosolic purine 5'-nucleotidase) DrugCentral uuid:36248578-7972-11ec-93d9-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3624af26-7972-11ec-93d9-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3624d974-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:36250278-7972-11ec-93d9-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (NS5B protein) DrugCentral uuid:36252744-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:36255138-7972-11ec-93d9-0242ac110002 UniProtKB:P9WGY9 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin targets Enzyme (DNA-directed RNA polymerase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:362587ca-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:362587ca-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:362587ca-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:362587ca-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:3625cd5c-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3625f6ba-7972-11ec-93d9-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:36261fbe-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:362648e0-7972-11ec-93d9-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:362671d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:36269b56-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3626c46e-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Enzyme (DNA-directed RNA polymerase subunit beta) DrugCentral uuid:3626ea20-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:36271324-7972-11ec-93d9-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.29']} DrugCentral uuid:36273d9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:362766a8-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:36278fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:3627c4c2-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:3627c4c2-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:3627c4c2-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:3627c4c2-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:36280914-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:36283d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:36283d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:36283d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:36283d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:36288286-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3628ab9e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3628d4d4-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:3628ff4a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:362928d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:362951fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:36297b14-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:3629a04e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3629c948-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.765']} DrugCentral uuid:3629f26a-7972-11ec-93d9-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:362a1b50-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:362a404e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:362a693e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:362a9332-7972-11ec-93d9-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:362abcc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:362ae738-7972-11ec-93d9-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:362b115e-7972-11ec-93d9-0242ac110002 UniProtKB:P21430 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Ion channel (Matrix protein 2) DrugCentral uuid:362b362a-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:362b5f1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:362b888c-7972-11ec-93d9-0242ac110002 UniProtKB:P63231 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine is inhibitor of Ion channel (Matrix protein 2) DrugCentral uuid:362bad62-7972-11ec-93d9-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:362bd684-7972-11ec-93d9-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:362bff9c-7972-11ec-93d9-0242ac110002 UniProtKB:P05778 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:362c2918-7972-11ec-93d9-0242ac110002 UniProtKB:P0DOF8 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:362c524e-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimexolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362cb1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:362d9258-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:362dbb84-7972-11ec-93d9-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:362de50a-7972-11ec-93d9-0242ac110002 UniProtKB:Q197X6 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:362e0e22-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WS26 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:362e3758-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:362e60ac-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:362e8b36-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:362eb430-7972-11ec-93d9-0242ac110002 UniProtKB:P04274 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:362edd70-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:362f069c-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:362f3036-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:362f5958-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:362f83b0-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:362facdc-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:362fd680-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:362fffb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:363028c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.788']} DrugCentral uuid:36305358-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:36307d6a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.443']} DrugCentral uuid:3630a68c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.364']} DrugCentral uuid:3630cfae-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3630f948-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:36312378-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:36314c86-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:363175b2-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:36319f24-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3631c864-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:3631f190-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.023']} DrugCentral uuid:36321aa8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:363244e2-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:36326e18-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:36329726-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.432']} DrugCentral uuid:3632c0b6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:3632e9c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.538']} DrugCentral uuid:36331304-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:36333c3a-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:363365c0-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:36338ef6-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.278']} DrugCentral uuid:3633b804-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3633e14e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:36340bb0-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:36343522-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:36345e12-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.687']} DrugCentral uuid:36348752-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3634b0d8-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3634da04-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.967']} DrugCentral uuid:363503c6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:36352dec-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3635575e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:36358080-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3635aad8-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:3635d530-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:3635fe5c-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:36362788-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:363650be-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:36367a3a-7972-11ec-93d9-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:3636a33e-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:3636cc60-7972-11ec-93d9-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3636f582-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:36371f44-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:36374866-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:36377188-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:36379b7c-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3637c660-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3637fae0-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3637fae0-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3637fae0-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3637fae0-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:36385058-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:36385058-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:36385058-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:36389946-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:36389946-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:36389946-7972-11ec-93d9-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3638dc80-7972-11ec-93d9-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:363905b6-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritodrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:36392f1e-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritodrine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:36395840-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.575']} DrugCentral uuid:363982f2-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:3639ad9a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:3639d6bc-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:3639ffac-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:363a24d2-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:363a4df4-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:363a76f8-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.303']} DrugCentral uuid:363aa024-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:363ac9e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.119']} DrugCentral uuid:363af48e-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:363b1dba-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.058']} DrugCentral uuid:363b46be-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:363b7292-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:363b9bbe-7972-11ec-93d9-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:363bc4d6-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:363bee48-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:363c174c-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:363c403c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.47']} DrugCentral uuid:363c6968-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:363c935c-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:363cbd5a-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:363ce6cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:363d0fda-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:363d3a8c-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:363d63a4-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:363d8cbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:363db5ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:363ddf5a-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:363e08e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:363e320c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:363e5be2-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:363e84fa-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:363eae44-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:363ed766-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.854']} DrugCentral uuid:363f024a-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:363f2ba8-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:363f54ca-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:363f7df6-7972-11ec-93d9-0242ac110002 UniProtKB:P79400 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:363fab46-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:363fab46-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:363fe840-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:363fe840-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:363fe840-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:364035ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:364035ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:364035ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:364035ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:36408584-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:3640ae92-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3640d890-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.466']} DrugCentral uuid:364101c6-7972-11ec-93d9-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:36412ad4-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:364153f6-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:36417d5e-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3641a680-7972-11ec-93d9-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3641cf8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:3641f892-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:36422272-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:36424b8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:364274ac-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:36429ec8-7972-11ec-93d9-0242ac110002 UniProtKB:P43351 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Nuclear other (DNA repair protein RAD52 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3642c9a2-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:3642f2d8-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:36431bfa-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:36434580-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:36436f88-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3643988c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3643c1a4-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3643eb84-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:364414ba-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:36443ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:364467f8-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:3644952a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3644be92-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3644e7b4-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:36451158-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:36453a70-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3645639c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:36458cbe-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:3645b252-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:3645d71e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:3645fbfe-7972-11ec-93d9-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:364620ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:3646464a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:36466d1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:364691f4-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:3646bb02-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:3646e488-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:36470d8c-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.391']} DrugCentral uuid:364736a4-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:36475fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3647897e-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:3647b2be-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:3647dbea-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:364804f8-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.82']} DrugCentral uuid:36483022-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:36485a48-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.449']} DrugCentral uuid:3648836a-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3648ac82-7972-11ec-93d9-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3648d5f4-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3648ff2a-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:36492856-7972-11ec-93d9-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:36495164-7972-11ec-93d9-0242ac110002 UniProtKB:P37238 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:36497b26-7972-11ec-93d9-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:3649a452-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3649cd56-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:3649f7cc-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:364a24ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:364a50fa-7972-11ec-93d9-0242ac110002 UniProtKB:B0K020 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:364a7a44-7972-11ec-93d9-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:364aa3c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:364accec-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:364af5f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5K1 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:364b1ef4-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:364b48e8-7972-11ec-93d9-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:364b7200-7972-11ec-93d9-0242ac110002 UniProtKB:O43924 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin targets Enzyme (Phosphodiesterase 6D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.9']} DrugCentral uuid:364b9b2c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:364bc516-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:364beeec-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:364c180e-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:364c4234-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:364c6cdc-7972-11ec-93d9-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:364c95fe-7972-11ec-93d9-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:364cbf48-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxatidine acetate is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:364ce86a-7972-11ec-93d9-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:364d0dea-7972-11ec-93d9-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin is agonist of GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:364d3716-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.261']} DrugCentral uuid:364d606a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rupatadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.41']} DrugCentral uuid:364d8982-7972-11ec-93d9-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:2413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rupatadine targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:364db56a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:364de1f2-7972-11ec-93d9-0242ac110002 UniProtKB:P17708 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (S-adenosylmethionine decarboxylase proenzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:364e0b28-7972-11ec-93d9-0242ac110002 UniProtKB:C3SIU2 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Unclassified (Met repressor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:364e3440-7972-11ec-93d9-0242ac110002 UniProtKB:P11086 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Phenylethanolamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:364e5dc6-7972-11ec-93d9-0242ac110002 UniProtKB:P22061 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Protein-beta-aspartate methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:364e86f2-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:364eb028-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:364edb02-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.95']} DrugCentral uuid:364f05aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q6RYA0 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Salicylic acid-binding protein 2) DrugCentral uuid:364f2a76-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:364f53b6-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:364f7e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:364fa7a8-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:364fd0d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:364ffa00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:36502412-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:36504d34-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:36507764-7972-11ec-93d9-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.36']} DrugCentral uuid:3650a07c-7972-11ec-93d9-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3650ca5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:3650f37e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:36511cbe-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.41']} DrugCentral uuid:36514702-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:3651704c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:36519978-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.004']} DrugCentral uuid:3651c27c-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3651ebe4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:365214de-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:36523e14-7972-11ec-93d9-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:36526894-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.408']} DrugCentral uuid:3652926a-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:3652bc2c-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:3652e54e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:36530e7a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.282']} DrugCentral uuid:3653390e-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.699']} DrugCentral uuid:36536230-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.555']} DrugCentral uuid:36538b52-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.556']} DrugCentral uuid:3653b4d8-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:3653d9a4-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.003']} DrugCentral uuid:365402d0-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.153']} DrugCentral uuid:36542c1a-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.187']} DrugCentral uuid:36545622-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.661']} DrugCentral uuid:36547f4e-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.684']} DrugCentral uuid:3654a97e-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:3654d2b4-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3654fd2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3655262e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:36554f6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:36557872-7972-11ec-93d9-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:3655a202-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:3655cb38-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:3655f45a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:36561d9a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:36564fae-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:36564fae-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:36564fae-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:3656911c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3656ba2a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.86']} DrugCentral uuid:3656e5ea-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:36570ef8-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:36573810-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:365761a0-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:36578acc-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:3657b3e4-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:3657dcfc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:365806aa-7972-11ec-93d9-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:36583f08-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:36583f08-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:36583f08-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:36583f08-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:36583f08-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:36589c14-7972-11ec-93d9-0242ac110002 UniProtKB:C3TDZ2 biolink:molecularly_interacts_with DrugCentral:2427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secnidazole targets Enzyme (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:3658c518-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.578']} DrugCentral uuid:3658f5f6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:3658f5f6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:3658f5f6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:36592fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.171']} DrugCentral uuid:36595938-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.764']} DrugCentral uuid:3659828c-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:3659abae-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:3659d584-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:3659fe9c-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:365a27be-7972-11ec-93d9-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:365a50cc-7972-11ec-93d9-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:365a7f8e-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:365a7f8e-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:365ab4b8-7972-11ec-93d9-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 seratrodast targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:365addc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:2433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sermorelin is agonist of GPCR (Growth hormone-releasing hormone receptor) DrugCentral uuid:365b029c-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:365b27d6-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertaconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:365b50e4-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:365b7a10-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:365ba3e6-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:365bccfe-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.194']} DrugCentral uuid:365bf724-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:365c2028-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:365c4b52-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:365c74ec-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:365c9e04-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:365cc71c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:365cf0a2-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:365d19c4-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:365d42f0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:365d6bfe-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:365d9a2a-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:365dc356-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:365dec6e-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:365e168a-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:365e3fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:365e68ce-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:365e91e6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:365ebb62-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:365ee47a-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:365f0d9c-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:365f36b4-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:365f608a-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:365f89c0-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:365fb2d8-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:365fe3b6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:365fe3b6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:365fe3b6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:3660319a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:3660319a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:3660319a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:366072fe-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:36609c98-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3660c5d8-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is inverse agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3660eefa-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.965']} DrugCentral uuid:3661181c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:366141e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:36616b32-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.54']} DrugCentral uuid:3661942c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3661bde4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.106']} DrugCentral uuid:3661e81e-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.666']} DrugCentral uuid:36621136-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.246']} DrugCentral uuid:36623a62-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:36626438-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.082']} DrugCentral uuid:36628ddc-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:3662b6f4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:3662e002-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:366309a6-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.854']} DrugCentral uuid:366332dc-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:36635d34-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.187']} DrugCentral uuid:36638656-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3663b158-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3663da70-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.475']} DrugCentral uuid:36640392-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.365']} DrugCentral uuid:36642cc8-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.885']} DrugCentral uuid:36645658-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:36647f70-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3664a892-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3664d254-7972-11ec-93d9-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:3664fb58-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:36652006-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive modulator of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:366544e6-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:36656ad4-7972-11ec-93d9-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:36658fc8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:3665b4a8-7972-11ec-93d9-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:3665d97e-7972-11ec-93d9-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:366637ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:3666fe1c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.526']} DrugCentral uuid:36672766-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:366752ea-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.962']} DrugCentral uuid:36677edc-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:3667a4e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.026']} DrugCentral uuid:3667ce14-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3667f7ae-7972-11ec-93d9-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:366820d0-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.538']} DrugCentral uuid:366849f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q62897 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:36687314-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:36689ce0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3668c5e4-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:3668efa6-7972-11ec-93d9-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Transporter (Multidrug resistance-associated protein 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:36691a1c-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:36694348-7972-11ec-93d9-0242ac110002 UniProtKB:P16499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) DrugCentral uuid:36696828-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3669912c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3669baa8-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3669e3b6-7972-11ec-93d9-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:366a0cf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13946 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:366a3604-7972-11ec-93d9-0242ac110002 UniProtKB:P51160 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:366a5fc6-7972-11ec-93d9-0242ac110002 UniProtKB:O76083 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:366a88ca-7972-11ec-93d9-0242ac110002 UniProtKB:O60658 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:366ab2be-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.094']} DrugCentral uuid:366adbfe-7972-11ec-93d9-0242ac110002 UniProtKB:O54735 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:366b0728-7972-11ec-93d9-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:366b3054-7972-11ec-93d9-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:366b596c-7972-11ec-93d9-0242ac110002 UniProtKB:P16586 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:366b82fc-7972-11ec-93d9-0242ac110002 UniProtKB:P11541 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:366bac14-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:366bd52c-7972-11ec-93d9-0242ac110002 UniProtKB:O77746 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:366c020e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:366c020e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:366c4386-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:366c4386-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:366c4386-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:366c4386-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:366c9c78-7972-11ec-93d9-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:366c9c78-7972-11ec-93d9-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:366c9c78-7972-11ec-93d9-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:366c9c78-7972-11ec-93d9-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:366cf61e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:366cf61e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:366cf61e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:366d3c82-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:366d3c82-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:366d855c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:366d855c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:366d855c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:366d855c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:366d855c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:366d855c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:366df47e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:366df47e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:366df47e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:366e35ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:366e5f04-7972-11ec-93d9-0242ac110002 UniProtKB:P14099 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:366e8812-7972-11ec-93d9-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:366eb1f2-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:366edb28-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:366f044a-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:366f2dda-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:366f5710-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:366f805a-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.73']} DrugCentral uuid:366fa97c-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:366fd3de-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:366ffd0a-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:36702622-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:36704f4e-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:3670792e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:3670a26e-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3670cb86-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3670f4a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:36711e56-7972-11ec-93d9-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:367148ea-7972-11ec-93d9-0242ac110002 UniProtKB:P21447 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Transporter (P-glycoprotein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3671722a-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:36719bd8-7972-11ec-93d9-0242ac110002 UniProtKB:P14142 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:3671c50e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:3671e9e4-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3672143c-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:36723ebc-7972-11ec-93d9-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:36726964-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3672925e-7972-11ec-93d9-0242ac110002 UniProtKB:Q10283 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:3672bb76-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.431']} DrugCentral uuid:3672e506-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:36730e0a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3673372c-7972-11ec-93d9-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:36736044-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:367389e8-7972-11ec-93d9-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:3673b2f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q00688 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3673dc0e-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:36740526-7972-11ec-93d9-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:36742f10-7972-11ec-93d9-0242ac110002 UniProtKB:Q13451 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3674585a-7972-11ec-93d9-0242ac110002 UniProtKB:Q53EL6 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Nuclear other (Programmed cell death protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3674815e-7972-11ec-93d9-0242ac110002 UniProtKB:P06730 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Nuclear other (Eukaryotic translation initiation factor 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3674aada-7972-11ec-93d9-0242ac110002 UniProtKB:P26883 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3674d3de-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:2447 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sisomicin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:3674f8be-7972-11ec-93d9-0242ac110002 UniProtKB:P14740 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:367521d6-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:36754d32-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.774']} DrugCentral uuid:36757654-7972-11ec-93d9-0242ac110002 UniProtKB:P28843 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:36759f6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3675c8a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3675f386-7972-11ec-93d9-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:36761ca8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHL4 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:367645c0-7972-11ec-93d9-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:36766eb0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:2449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitafloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:367693cc-7972-11ec-93d9-0242ac110002 UniProtKB:P72525 biolink:molecularly_interacts_with DrugCentral:2449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitafloxacin targets Enzyme (DNA topoisomerase 4 subunit A) DrugCentral uuid:3676b8a2-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:3676e1c4-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:36770b0e-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:367734e4-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:36775dfc-7972-11ec-93d9-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:367786f6-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:3677b022-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3677db56-7972-11ec-93d9-0242ac110002 UniProtKB:P06746 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (DNA polymerase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:3678046e-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:36782ec6-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:36785842-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:36788182-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:3678aa9a-7972-11ec-93d9-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3678d394-7972-11ec-93d9-0242ac110002 UniProtKB:P24158 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Myeloblastin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3678fd42-7972-11ec-93d9-0242ac110002 UniProtKB:Q3UP87 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:3679265a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:36794f90-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:367979ac-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.88']} DrugCentral uuid:3679a440-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3679cd62-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3679f68e-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:367a1fce-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:367a4972-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:367a7294-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:367a9c4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:367ac636-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:367aef62-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:367b1898-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:367b41ce-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:367b6c8a-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:367b9908-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:367bc2d4-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:367bec00-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:367c15a4-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:367c3ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:367c67fc-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:367c911e-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:367cbae0-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:367ce3ee-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:367d0d24-7972-11ec-93d9-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:367d3754-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:367d6314-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:367d8d3a-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:367db670-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:367ddff6-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:367e094a-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.68']} DrugCentral uuid:367e33c0-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:367e5d0a-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:367e86cc-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:367eafee-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:367ed91a-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:367f0228-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:367f2c3a-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:367f5566-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:367f7e88-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:367fa818-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:367fd144-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:367ffa66-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:36802392-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:36804d40-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:368076f8-7972-11ec-93d9-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3680a0b0-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3680c9c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3680f3a8-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:36811cd4-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:36814600-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:36816f0e-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:368199ca-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3681c2ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3681ec22-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:36821558-7972-11ec-93d9-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:36823f1a-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:36826832-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:36829136-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3682bb84-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3682e47e-7972-11ec-93d9-0242ac110002 UniProtKB:P53778 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:36830daa-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:368336cc-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:36836048-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3683896a-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3683b26e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3683dbae-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:3684058e-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:36842eb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3684591c-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3684823e-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3684ac3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3684d55e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3684fe8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:36852810-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3685513c-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:36857a54-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3685a466-7972-11ec-93d9-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3685ce5a-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3685f75e-7972-11ec-93d9-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3686208a-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:36864998-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:368673fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:36869d08-7972-11ec-93d9-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3686c634-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3686ef56-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:368718dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3687426c-7972-11ec-93d9-0242ac110002 UniProtKB:O15264 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:36876b98-7972-11ec-93d9-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:36879528-7972-11ec-93d9-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3687be5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3687e780-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:368810a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:36883b22-7972-11ec-93d9-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:3688646c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:36888d8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3688b6b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3688e036-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3689094e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:36893266-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:36895b7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:3689854a-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3689af5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3689d860-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:368a0196-7972-11ec-93d9-0242ac110002 UniProtKB:P49336 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:368a2b94-7972-11ec-93d9-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:368a54ca-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:368a7f04-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:368aa894-7972-11ec-93d9-0242ac110002 UniProtKB:Q00526 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:368ad1c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:368afae2-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:368b2404-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:368b4dc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:368b76f2-7972-11ec-93d9-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:368ba014-7972-11ec-93d9-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:368bc918-7972-11ec-93d9-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:368bf384-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVW4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase-like 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:368c1cb0-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:368c45dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:368c6efe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:368c9884-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:368cc1a6-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:368cead2-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:368d1494-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:368d3dc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:368d66e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:368d8ff0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:368dbb6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:368de4c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:368e0dea-7972-11ec-93d9-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:368e3720-7972-11ec-93d9-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:368e613c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5GIT4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:368e8a54-7972-11ec-93d9-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:368eb362-7972-11ec-93d9-0242ac110002 UniProtKB:Q8T9Z7 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:368edc8e-7972-11ec-93d9-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:368f0650-7972-11ec-93d9-0242ac110002 UniProtKB:P05622 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:368f2f7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:368f58a8-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:368f81c0-7972-11ec-93d9-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:368faede-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:368fd800-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:36900136-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:36902ab2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:369053c0-7972-11ec-93d9-0242ac110002 UniProtKB:P09250 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:36907cba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XZT6 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Deoxynucleoside kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:3690a6fe-7972-11ec-93d9-0242ac110002 UniProtKB:O00142 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:3690d0ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3690fa00-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:36912336-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:36914c58-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:36917642-7972-11ec-93d9-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:36919f50-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.413']} DrugCentral uuid:3691cd90-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:3691cd90-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:3692012a-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:3692012a-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:3692306e-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:2468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spectinomycin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:3692553a-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2469 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiclomazine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:36927e34-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:3692a832-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:3692d154-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3692fa58-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:36932398-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:36934fd0-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:36937a96-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:3693a3c2-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3693cdd4-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3693f6f6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3694202c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:3694493a-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:36947306-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.322']} DrugCentral uuid:36949c14-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3694c522-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3694ee3a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:369519be-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:36954330-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:36956c48-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:3695956a-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.297']} DrugCentral uuid:3695bee6-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:3695e8f8-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3696121a-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:36963bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:369664f4-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:36968f56-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3696b878-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3696e2a8-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:36970bde-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3697350a-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:36975e22-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.87']} DrugCentral uuid:369787a8-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3697b0de-7972-11ec-93d9-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3697e914-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3697e914-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3697e914-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3697e914-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3697e914-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:36984ea4-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:36984ea4-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:36984ea4-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:36984ea4-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3698abce-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3698abce-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3698abce-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3698abce-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3698abce-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:36990e3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:36990e3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:36990e3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:369957e0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:369957e0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:369957e0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:3699a858-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3699a858-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3699a858-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3699a858-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3699a858-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:369a0226-7972-11ec-93d9-0242ac110002 UniProtKB:P02665 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Unclassified (Beta-casein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:369a2b3e-7972-11ec-93d9-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:369a5460-7972-11ec-93d9-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:369a7daa-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spirapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:369aa96a-7972-11ec-93d9-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:2474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spirapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:369ad3ae-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.227']} DrugCentral uuid:369afd52-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:369b22aa-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.884']} DrugCentral uuid:369b4bc2-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:369b752a-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.029']} DrugCentral uuid:369b9e2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:369bc7be-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:369bf0e0-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:369c19ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.663']} DrugCentral uuid:369c4400-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:369c6fca-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.033']} DrugCentral uuid:369c9aae-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.327']} DrugCentral uuid:369cc3e4-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:369ced2e-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:369d1254-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.948']} DrugCentral uuid:369d3b4e-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:369d6466-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:369d8e0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.316']} DrugCentral uuid:369db740-7972-11ec-93d9-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:369ddc2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:369e0524-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:369e2f4a-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:369e54d4-7972-11ec-93d9-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:369e7df6-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 1A2) DrugCentral uuid:369ea2d6-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:369ec81a-7972-11ec-93d9-0242ac110002 UniProtKB:P9WH62 biolink:molecularly_interacts_with DrugCentral:2481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 streptomycin targets Ribosomal protein (30S ribosomal protein S12) DrugCentral uuid:369eed22-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:369f1680-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:369f3fa2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:369f6982-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:369f92ae-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:369fc378-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:369fc378-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:369fc378-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:36a005ae-7972-11ec-93d9-0242ac110002 UniProtKB:P07727 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:36a02fc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYW0 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets GPCR (Taste receptor type 2 member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:36a058e2-7972-11ec-93d9-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is agonist of GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.367']} DrugCentral uuid:36a081dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:2487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinic acid targets Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:36a0acac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BXA5 biolink:molecularly_interacts_with DrugCentral:2487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinic acid is agonist of GPCR (Succinate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:36a0d5b0-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:36a10ee0-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:36a10ee0-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:36a10ee0-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:36a10ee0-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:36a10ee0-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:36a15e9a-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:36a18794-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:36a1b098-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:36a1db40-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:36a2046c-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:36a22dac-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:36a26222-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:36a26222-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:36a26222-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:36a26222-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:36a2afca-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:36a2d8ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:36a301dc-7972-11ec-93d9-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:36a32b94-7972-11ec-93d9-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:36a354ac-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:36a37e3c-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:36a3a92a-7972-11ec-93d9-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:36a3d274-7972-11ec-93d9-0242ac110002 UniProtKB:P13661 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase OXA-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:36a3fb6e-7972-11ec-93d9-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:36a42472-7972-11ec-93d9-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:36a44de4-7972-11ec-93d9-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:36a476f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:36a4a00a-7972-11ec-93d9-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:36a4c940-7972-11ec-93d9-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:36a4f2f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q7X575 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:36a51c06-7972-11ec-93d9-0242ac110002 UniProtKB:Q0VTR6 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:36a54514-7972-11ec-93d9-0242ac110002 UniProtKB:Q0VTR8 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:36a56e18-7972-11ec-93d9-0242ac110002 UniProtKB:D5HSX5 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:36a598b6-7972-11ec-93d9-0242ac110002 UniProtKB:P83111 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Serine beta-lactamase-like protein LACTB, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:36a5c1ba-7972-11ec-93d9-0242ac110002 UniProtKB:P62594 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:36a5ebfe-7972-11ec-93d9-0242ac110002 UniProtKB:Q0VTS0 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (ADC-18 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:36a6152a-7972-11ec-93d9-0242ac110002 UniProtKB:P00809 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:36a63ea6-7972-11ec-93d9-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:36a667dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:36a6916c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.819']} DrugCentral uuid:36a6bb60-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.155']} DrugCentral uuid:36a6e482-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:36a70d90-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:36a736bc-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:36a76128-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.716']} DrugCentral uuid:36a78a54-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:36a7b39e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.786']} DrugCentral uuid:36a7ddba-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.977']} DrugCentral uuid:36a8074a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.053']} DrugCentral uuid:36a83076-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.142']} DrugCentral uuid:36a859c0-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.258']} DrugCentral uuid:36a882ec-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.727']} DrugCentral uuid:36a8accc-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.144']} DrugCentral uuid:36a8d60c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:36a8ff42-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:36a92954-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:36a95474-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:36a97936-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:36a9a244-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:36a9cbb6-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:36a9f4ec-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:36aa1e22-7972-11ec-93d9-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:36aa4730-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.431']} DrugCentral uuid:36aa70fc-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.738']} DrugCentral uuid:36aa9a1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:36aac340-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:36aaec6c-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.782']} DrugCentral uuid:36ab1714-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:36ab402c-7972-11ec-93d9-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:36ab6958-7972-11ec-93d9-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:36ab9270-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:36abbc00-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36abe0d6-7972-11ec-93d9-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:36ac0c96-7972-11ec-93d9-0242ac110002 UniProtKB:Q25704 biolink:molecularly_interacts_with DrugCentral:2499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacytine is inhibitor of Kinase (7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase) DrugCentral uuid:36ac314e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:36ac5ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:36ac83ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q08210 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) DrugCentral uuid:36aca8a4-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36accd70-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:36acf75a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZV3 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:36ad207c-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimethoxine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.206']} DrugCentral uuid:36ad49a8-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimidine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36ad6f32-7972-11ec-93d9-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimidine targets Enzyme (Lactoylglutathione lyase) DrugCentral uuid:36ad941c-7972-11ec-93d9-0242ac110002 UniProtKB:Q25704 biolink:molecularly_interacts_with DrugCentral:2503 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadoxine is inhibitor of Kinase (7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase) DrugCentral uuid:36adb8e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IAU3 biolink:molecularly_interacts_with DrugCentral:2503 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadoxine targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:36ade214-7972-11ec-93d9-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:2504 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaethidole targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:36af3e02-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:36afcc32-7972-11ec-93d9-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:36afcc32-7972-11ec-93d9-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:36afcc32-7972-11ec-93d9-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:36b053a0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2510 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamerazine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36b09eaa-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfameter is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36b0e888-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethizole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36b1282a-7972-11ec-93d9-0242ac110002 UniProtKB:P08192 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Bifunctional protein FolC) DrugCentral uuid:36b1511a-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole is inhibitor of Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:36b17f46-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:36b1ad04-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:36b1db44-7972-11ec-93d9-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:36b208f8-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfalene is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36b231f2-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:36b2601e-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:36b28fbc-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:36b2bd52-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:36b2ec64-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:36b31be4-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36b344ac-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:36b37242-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:36b3a05a-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:36b3ce04-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:36b3fb9a-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:36b42c6e-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:36b45a22-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:36b487d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:36b4b56c-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:36b4e668-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:36b5141c-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:36b541c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:36b56fe8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:36b59dd8-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:36b5cb6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:36b5f9ae-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:36b62758-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:36b65502-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:36b682a2-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:36b6b3bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:36b6e152-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:36b70ede-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:36b73dd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:36b76b7c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:36b79912-7972-11ec-93d9-0242ac110002 UniProtKB:P00921 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:36b7c6a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:36b7f4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:36b82242-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:36b84ff6-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaphenazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:36b87ec2-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaphenazole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36b8a7a8-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfapyridine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36b8d08e-7972-11ec-93d9-0242ac110002 UniProtKB:Q49184 biolink:molecularly_interacts_with DrugCentral:2524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfapyridine targets Enzyme (Dihydropteroate synthase type-1) DrugCentral uuid:36b8f956-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:36b92764-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:36b95522-7972-11ec-93d9-0242ac110002 UniProtKB:P24752 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Acetyl-CoA acetyltransferase, mitochondrial) DrugCentral uuid:36b97dfe-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:36b9a78e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Cystine/glutamate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:36b9d51a-7972-11ec-93d9-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:36ba0300-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.707']} DrugCentral uuid:36ba3096-7972-11ec-93d9-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.628']} DrugCentral uuid:36ba6016-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.533']} DrugCentral uuid:36ba8dc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:36babc78-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.768']} DrugCentral uuid:36baea5e-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.198']} DrugCentral uuid:36bb1c36-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:36bb1c36-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:36bb5106-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:36bb7f6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:36bbad0e-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole is inhibitor of Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:36bbdb94-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.161']} DrugCentral uuid:36bc092a-7972-11ec-93d9-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:36bc3ac6-7972-11ec-93d9-0242ac110002 UniProtKB:P25084 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets Unclassified (Transcriptional activator protein LasR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:36bc687a-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:36bc9142-7972-11ec-93d9-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:36bcbf78-7972-11ec-93d9-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:36bcecfa-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:36bd1aa4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:36bd4812-7972-11ec-93d9-0242ac110002 UniProtKB:Q08210 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) DrugCentral uuid:36bd71ac-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:36bd9a7e-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:36bdc80a-7972-11ec-93d9-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:36bdf776-7972-11ec-93d9-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:36be2598-7972-11ec-93d9-0242ac110002 UniProtKB:O60760 biolink:molecularly_interacts_with DrugCentral:2531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfobromophthalein targets Enzyme (Hematopoietic prostaglandin D synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:36be5310-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulforidazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.611']} DrugCentral uuid:36be809c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulforidazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:36beaeb4-7972-11ec-93d9-0242ac110002 UniProtKB:P0C0X1 biolink:molecularly_interacts_with DrugCentral:2533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesulfone is inhibitor of Enzyme (Dihydropteroate synthase 1) DrugCentral uuid:36bed786-7972-11ec-93d9-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesulfone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:36bf0062-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:36bf2e8e-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:36bf5c1a-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:36bf8974-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:36bfb6d8-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:36bfe554-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (72 kDa type IV collagenase) DrugCentral uuid:36c00e3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:36c03bd0-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.362']} DrugCentral uuid:36c069b6-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:36c0983c-7972-11ec-93d9-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:36c0c654-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:36c0f462-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:36c1236a-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:36c150e2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:36c17e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.307']} DrugCentral uuid:36c1aefc-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:36c1dcd8-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.857']} DrugCentral uuid:36c20a64-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.508']} DrugCentral uuid:36c23890-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:36c26630-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.146']} DrugCentral uuid:36c293e4-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.606']} DrugCentral uuid:36c2c166-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.053']} DrugCentral uuid:36c2efba-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.965']} DrugCentral uuid:36c31d50-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.009']} DrugCentral uuid:36c34af0-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.196']} DrugCentral uuid:36c37ad4-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:36c3a8f6-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.426']} DrugCentral uuid:36c3d68c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:36c404a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:36c4321c-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:36c45fbc-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:36c48d48-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.141']} DrugCentral uuid:36c4bbb0-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.645']} DrugCentral uuid:36c4e914-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:36c517b8-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:36c546f2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.121']} DrugCentral uuid:36c57866-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:36c5a688-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:36c5d414-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:36c601f0-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:36c62f72-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:36c65cf4-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:36c68b48-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:36c6b8d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:36c6e67e-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:36c71540-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:36c74344-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:36c77152-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:36c79efc-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:36c7ce4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GJU1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:36c7fbd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:36c82994-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:36c857de-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:36c885c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:36c8b346-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:36c8e0dc-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:36c912aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:36c9404a-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:36c96de0-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:36c99be4-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:36c9ca9c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:36ca0908-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:36ca0908-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:36ca0908-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:36ca0908-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:36ca0908-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:36ca6dd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:36ca9b70-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:36cacb0e-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:36caf8ea-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:36cb2680-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:36cb5452-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:36cb8224-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:36cbafc4-7972-11ec-93d9-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:36cbdd64-7972-11ec-93d9-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:36cc0bae-7972-11ec-93d9-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.38']} DrugCentral uuid:36cc3926-7972-11ec-93d9-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:36cc66ee-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:36cc95d8-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:36ccc3d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:36ccf14a-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:36cd1ef4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:36cd4ce4-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:36cd7aa2-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:36cda860-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:36cdd6aa-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:36ce05bc-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:36ce34ce-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:36ce6368-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:36ce914e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:36cebec6-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:36ceec48-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:36cf1a42-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:36cf47ba-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2541 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.571']} DrugCentral uuid:36cf753c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2541 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultopride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:36cfa39a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:36cfd130-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:36cffed0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:36d02c34-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:36d05ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:36d08aa8-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:36d0b866-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:36d0e67e-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:36d113f6-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:36d14178-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:36d16fa4-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:36d19d30-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:36d1cabc-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:36d1f848-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:36d228ae-7972-11ec-93d9-0242ac110002 UniProtKB:P79400 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:36d25630-7972-11ec-93d9-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:36d284b6-7972-11ec-93d9-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:36d2b2a6-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:36d2e046-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:36d30dd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N2B7 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:36d33b5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8MI13 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Unclassified (5-hydroxytryptamine 1D receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:36d3698a-7972-11ec-93d9-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:36d3972a-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:36d3c4b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:36d3f314-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:36d4208c-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.12']} DrugCentral uuid:36d44e4a-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:36d47c30-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:36d4aa3e-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:36d4d7ca-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:36d50696-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:36d534d6-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:36d56280-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:36d59034-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.66']} DrugCentral uuid:36d5bf50-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:36d5ecfa-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:36d61acc-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:36d64862-7972-11ec-93d9-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:36d6765c-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:36d6a406-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:36d6d19c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:36d700fe-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:36d72ea8-7972-11ec-93d9-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:36d75c3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:36d78a9c-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:36d7baa8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:36d7e85c-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:36d815de-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:36d8445a-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:36d871fa-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:36d89f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:36d8cdee-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:36d8fb66-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:36d928fc-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:36d956b0-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:36d98702-7972-11ec-93d9-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:36d9b498-7972-11ec-93d9-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:36d9e21a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:36da101e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:36da3daa-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:36da6b90-7972-11ec-93d9-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:36da99ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:36dac78e-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:36daf52e-7972-11ec-93d9-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:36db229c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:36db5384-7972-11ec-93d9-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:36db85fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:36dbb52c-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:36dbe3c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.26']} DrugCentral uuid:36dc1184-7972-11ec-93d9-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:36dc3f1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:36dc6d78-7972-11ec-93d9-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:36dc9b0e-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:36dcc8ae-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:36dcf63a-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:36dd26e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:36dd5472-7972-11ec-93d9-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:36dd821c-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:36ddb00c-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:36ddddac-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:36de0b42-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:36de38d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:36de672c-7972-11ec-93d9-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:36de94c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:36dec23a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:36def192-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:36df1f28-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:36df4caa-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:36df7a86-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:36dfa808-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:36dfd5c6-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:36e00456-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.26']} DrugCentral uuid:36e032be-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:36e0604a-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:36e08dea-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:36e0bc7a-7972-11ec-93d9-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:36e0ea10-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2H1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 38-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:36e117ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:36e1455a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:36e17372-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:36e1a126-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:36e1ceda-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:36e1fd24-7972-11ec-93d9-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:36e22aba-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:36e25846-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:36e28870-7972-11ec-93d9-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:36e2b6a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:36e2e45a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:36e311e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:36e33ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:36e36db2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:36e39bf2-7972-11ec-93d9-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:36e3ca46-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:36e3f7dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:36e4255e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:36e452fe-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:36e483dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:36e4b172-7972-11ec-93d9-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:36e4df08-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:36e50d02-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:36e53a8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:36e56842-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JI10 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:36e596aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:36e5c44a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:36e5f1c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:36e61f76-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:36e6500e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:36e67da4-7972-11ec-93d9-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:36e6ab3a-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:36e6d934-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:36e706de-7972-11ec-93d9-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:36e73460-7972-11ec-93d9-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:36e761e2-7972-11ec-93d9-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:36e79040-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:36e7bdc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:36e7eb6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:36e81b28-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:36e848d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:36e87686-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:36e8a494-7972-11ec-93d9-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:36e8d234-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:36e90100-7972-11ec-93d9-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:36e92e78-7972-11ec-93d9-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:36e95e34-7972-11ec-93d9-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:36e98bb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:36e9b94c-7972-11ec-93d9-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:36e9e796-7972-11ec-93d9-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:36ea1536-7972-11ec-93d9-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:36ea42c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:36ea7062-7972-11ec-93d9-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:36ea9e70-7972-11ec-93d9-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:36eacc06-7972-11ec-93d9-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:36eafa14-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:36eb2868-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N752 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform alpha-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:36eb5626-7972-11ec-93d9-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:36eb83b2-7972-11ec-93d9-0242ac110002 UniProtKB:P78368 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:36ebb26a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:36ebe06e-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:36ec0e2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:36ec3bc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:36ec69da-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:36ec977a-7972-11ec-93d9-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:36ecc51a-7972-11ec-93d9-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:36ecf350-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:36ed20dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:36ed4e7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:36ed7d20-7972-11ec-93d9-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:36edabba-7972-11ec-93d9-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:36edd950-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:36ee06fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:36ee34e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:36ee6280-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:36ee9016-7972-11ec-93d9-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:36eebe74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:36eeec00-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:36ef19a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:36ef4754-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:36ef77c4-7972-11ec-93d9-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:36efa564-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:36efd2f0-7972-11ec-93d9-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:36f000ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:36f02fca-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:36f05d6a-7972-11ec-93d9-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:36f08aec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:36f0b94a-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:36f0e6e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:36f11476-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:36f143e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:36f17182-7972-11ec-93d9-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:36f19f0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:36f1cd26-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:36f1fba2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:36f22924-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:36f256c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:36f2859a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDC3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase BRSK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:36f2b33a-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:36f2e0b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:36f30f38-7972-11ec-93d9-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:36f33cba-7972-11ec-93d9-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:36f36a6e-7972-11ec-93d9-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:36f397fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:36f3c612-7972-11ec-93d9-0242ac110002 UniProtKB:Q16566 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:36f3f39e-7972-11ec-93d9-0242ac110002 UniProtKB:P11799 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:36f42148-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:36f44f6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:36f47cf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:36f4aaa0-7972-11ec-93d9-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:36f4d944-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:36f50748-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCP0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:36f534de-7972-11ec-93d9-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:36f56274-7972-11ec-93d9-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:36f5908c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:36f5be04-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:36f5eb90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:36f619bc-7972-11ec-93d9-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:36f6472a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IWQ3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase BRSK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:36f675ba-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:36f6a33c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:36f6d424-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:36f702fa-7972-11ec-93d9-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:36f730ae-7972-11ec-93d9-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:36f75eb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:36f78c48-7972-11ec-93d9-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:36f7b9d4-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:36f7e828-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:36f815aa-7972-11ec-93d9-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:36f84354-7972-11ec-93d9-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:36f870e0-7972-11ec-93d9-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:36f8a132-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:36f8cec8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:36f8fc68-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:36f92a4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:36f957da-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:36f98570-7972-11ec-93d9-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:36f9b306-7972-11ec-93d9-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:36f9e146-7972-11ec-93d9-0242ac110002 UniProtKB:P80370 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Unclassified (Protein delta homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:36fa0f7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:36fa3d26-7972-11ec-93d9-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:36fa6d6e-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:36fa9c3a-7972-11ec-93d9-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:36faca02-7972-11ec-93d9-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:36faf900-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:36fb26aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:36fb5436-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:36fb81cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:36fbb00c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:36fbddac-7972-11ec-93d9-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:36fc0b42-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:36fc3ad6-7972-11ec-93d9-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:36fc69d4-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:36fc976a-7972-11ec-93d9-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:36fcc582-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:36fcf32c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:36fd20c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:36fd4e4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15208 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:36fd7c84-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:36fdaa10-7972-11ec-93d9-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:36fdd8e6-7972-11ec-93d9-0242ac110002 UniProtKB:O43172 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Nuclear other (U4/U6 small nuclear ribonucleoprotein Prp4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:36fe07e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:36fe35d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.23']} DrugCentral uuid:36fe6374-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:36fe913c-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:36febf4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:36feecb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:36ff1a4e-7972-11ec-93d9-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:36ff49ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:36ff7764-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:36ffa4e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:36ffd326-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:370000bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:37002e7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:37005c1a-7972-11ec-93d9-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:37008a1e-7972-11ec-93d9-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3700b7b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3700e536-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.05']} DrugCentral uuid:37011358-7972-11ec-93d9-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:370140e4-7972-11ec-93d9-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:37016e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:37019c06-7972-11ec-93d9-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3701ca82-7972-11ec-93d9-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3701f82c-7972-11ec-93d9-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3702264e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRH2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SNF-related serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:37025470-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:370281fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:3702afa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3702dd3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:37030b72-7972-11ec-93d9-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:37033908-7972-11ec-93d9-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3703669e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H8M2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Unclassified (Bromodomain-containing protein 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:370396dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3703c58a-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.509']} DrugCentral uuid:3703f33e-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:37042156-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.229']} DrugCentral uuid:37044f00-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.959']} DrugCentral uuid:37047c96-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3704ab8a-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3704d9c0-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.347']} DrugCentral uuid:37050756-7972-11ec-93d9-0242ac110002 UniProtKB:P47872 biolink:molecularly_interacts_with DrugCentral:2548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secretin human is agonist of GPCR (Secretin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:370534e2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:3705632c-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:37059090-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:3705be08-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:3705ebbc-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:37061998-7972-11ec-93d9-0242ac110002 UniProtKB:Q04844 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Acetylcholine receptor subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:37064724-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:3706749c-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3706a2b4-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:3706d018-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3706fd7c-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:37072c3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:37075cfe-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:37078a58-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3707b7e4-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3707e5e8-7972-11ec-93d9-0242ac110002 UniProtKB:P32738 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Choline O-acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:37081388-7972-11ec-93d9-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:370841fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:37087058-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:37089dda-7972-11ec-93d9-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3708cbde-7972-11ec-93d9-0242ac110002 UniProtKB:Q01984 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Histamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3708f9f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:37092ab6-7972-11ec-93d9-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:37095842-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.61']} DrugCentral uuid:37098a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:37098a24-7972-11ec-93d9-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:3709ca02-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3709ca02-7972-11ec-93d9-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:370a15de-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:370a15de-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:370a15de-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:370a15de-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:370a15de-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:370a7a7e-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.91']} DrugCentral uuid:370aa7ec-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:370ad80c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:370b05de-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:370b336a-7972-11ec-93d9-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:370b60ec-7972-11ec-93d9-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:370b8ef0-7972-11ec-93d9-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.398']} DrugCentral uuid:370bbc86-7972-11ec-93d9-0242ac110002 UniProtKB:P60568 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interleukin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.72']} DrugCentral uuid:370be9fe-7972-11ec-93d9-0242ac110002 UniProtKB:P48454 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:370c1956-7972-11ec-93d9-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:370c46c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:370c7450-7972-11ec-93d9-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:370ca1d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13451 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:370cd076-7972-11ec-93d9-0242ac110002 UniProtKB:Q15393 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Nuclear other (Splicing factor 3B subunit 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:370cfe02-7972-11ec-93d9-0242ac110002 UniProtKB:Q96AY3 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:370d2b98-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:370d59b0-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:370d875a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:370db4f0-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:370de330-7972-11ec-93d9-0242ac110002 UniProtKB:O54735 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:370e10d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:370e3e66-7972-11ec-93d9-0242ac110002 UniProtKB:P11541 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:370e82d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:370e82d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:370e82d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:370e82d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:370e82d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:370e82d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:370f09c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:370f09c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:370f09c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:370f09c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:370f09c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:370f09c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:370f7c86-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:370fea90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:3710cffa-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3710fdd6-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:37112b3a-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:3711540c-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:37118166-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3711afba-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3711dd00-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:37120a6e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.915']} DrugCentral uuid:3712394e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:371266c6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:3712942a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:3712c346-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3712f0aa-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:37131e54-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:37134bcc-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:371379f8-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3713a77a-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:3713ddb2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3713ddb2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3713ddb2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:37142a92-7972-11ec-93d9-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:2560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 taltirelin is agonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3714583c-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.807']} DrugCentral uuid:371485aa-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.001']} DrugCentral uuid:3714b3ae-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3714e11c-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.357']} DrugCentral uuid:37150ebc-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:37153d60-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.372']} DrugCentral uuid:37156c40-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.335']} DrugCentral uuid:371599a4-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3715c726-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.139']} DrugCentral uuid:3715f5de-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:3716236a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:371650d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:37167ec8-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3716ac68-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.907']} DrugCentral uuid:3716d9ea-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:3717092e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.158']} DrugCentral uuid:371736c4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:3717645a-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:371791fa-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.618']} DrugCentral uuid:3717c260-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:3717f082-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.794']} DrugCentral uuid:37181e18-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:37184bf4-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.034']} DrugCentral uuid:37187976-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.167']} DrugCentral uuid:3718a6ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.557']} DrugCentral uuid:3718d47a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:371902ba-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:37193046-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.731']} DrugCentral uuid:37195da0-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:37198c12-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.238']} DrugCentral uuid:3719b99e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.835']} DrugCentral uuid:3719e702-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.858']} DrugCentral uuid:371a14f2-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:371a4274-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:371a6fce-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.407']} DrugCentral uuid:371a9d32-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.611']} DrugCentral uuid:371acb68-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.204']} DrugCentral uuid:371af91c-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:371b269e-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:371b5524-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.328']} DrugCentral uuid:371b83f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:371bb15e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:371bdec2-7972-11ec-93d9-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Estrogen-related receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:371c0c9e-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.449']} DrugCentral uuid:371c3b7e-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.069']} DrugCentral uuid:371c68f6-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.095']} DrugCentral uuid:371c96fa-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.923']} DrugCentral uuid:371cc47c-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:371cf1cc-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.038']} DrugCentral uuid:371d2048-7972-11ec-93d9-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:371d4e42-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.913']} DrugCentral uuid:371d7b9c-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.821']} DrugCentral uuid:371da914-7972-11ec-93d9-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.919']} DrugCentral uuid:371dd6f0-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.533']} DrugCentral uuid:371e047c-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.604']} DrugCentral uuid:371e3208-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.761']} DrugCentral uuid:371e6052-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.419']} DrugCentral uuid:371e8e74-7972-11ec-93d9-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.515']} DrugCentral uuid:371ebbd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.587']} DrugCentral uuid:371ee95a-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:371f177c-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:371f44f4-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:371f728a-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.061']} DrugCentral uuid:371fa052-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY08 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Emopamil-binding protein-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:371fd216-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBM7 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Anti-estrogen binding site (AEBS)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:371fd216-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBM7 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Anti-estrogen binding site (AEBS)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:37200e70-7972-11ec-93d9-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:37203ca6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:37206a32-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.87']} DrugCentral uuid:372097e6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3720c572-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:3720f3d0-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.54']} DrugCentral uuid:37212170-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:37214ede-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:37217cec-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.24']} DrugCentral uuid:3721aa8c-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:3721d82c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:37220662-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:372233ee-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:37226166-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:37228efc-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3722ca34-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3722ca34-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3722ca34-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3722ca34-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:372321b4-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:37234fae-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:37237d58-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:3723aaf8-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3723d94c-7972-11ec-93d9-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:372407e6-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:37243540-7972-11ec-93d9-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:3724627c-7972-11ec-93d9-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.527']} DrugCentral uuid:37249328-7972-11ec-93d9-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.602']} DrugCentral uuid:3724c096-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3724ede6-7972-11ec-93d9-0242ac110002 UniProtKB:Q59401 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:37251b9a-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:372548ea-7972-11ec-93d9-0242ac110002 UniProtKB:P10424 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.524']} DrugCentral uuid:3725763a-7972-11ec-93d9-0242ac110002 UniProtKB:Q46991 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (IMI-1; IMI-1 carbapenemase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3725a39e-7972-11ec-93d9-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3725d1b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q6W9J1 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3725ff10-7972-11ec-93d9-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:37262c6a-7972-11ec-93d9-0242ac110002 UniProtKB:P94958 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:37265aa0-7972-11ec-93d9-0242ac110002 UniProtKB:P05193 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:372687f0-7972-11ec-93d9-0242ac110002 UniProtKB:A4KCT8 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3726b554-7972-11ec-93d9-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3726e330-7972-11ec-93d9-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:372710a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:37273e16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9F663 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Carbepenem-hydrolyzing beta-lactamase KPC) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:37276b84-7972-11ec-93d9-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:37279992-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3727c6f6-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD64 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3727f46e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6GWS8 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3728229a-7972-11ec-93d9-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:37285008-7972-11ec-93d9-0242ac110002 UniProtKB:A0ZX81 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:37287d6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3728abd4-7972-11ec-93d9-0242ac110002 UniProtKB:B8R6A5 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3728d992-7972-11ec-93d9-0242ac110002 UniProtKB:Q2XPY6 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:37290700-7972-11ec-93d9-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:37293450-7972-11ec-93d9-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:37296394-7972-11ec-93d9-0242ac110002 UniProtKB:Q670S6 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:372990e4-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3729be2a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 1A) DrugCentral uuid:3729e6f2-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:372a1776-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 1D) DrugCentral uuid:372a402a-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:372a6dca-7972-11ec-93d9-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod is partial agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:372a9bb0-7972-11ec-93d9-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:2580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teicoplanin aglycone is inhibitor of Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:372ac928-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:372af68c-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:372b242c-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:372b52da-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.31']} DrugCentral uuid:372b8066-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:372badd4-7972-11ec-93d9-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:372bdc78-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:372c09e6-7972-11ec-93d9-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:372c3772-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:372c6512-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:372c9654-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:372c9654-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:372c9654-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:372cd696-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temocapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.444']} DrugCentral uuid:372d05e4-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temocapril is inhibitor of Enzyme (Angiotensin-converting enzyme) DrugCentral uuid:372d2e84-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:372d5756-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:372d8000-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:372da990-7972-11ec-93d9-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:372dd244-7972-11ec-93d9-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Canalicular multispecific organic anion transporter 2) DrugCentral uuid:372dfb02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:372e2870-7972-11ec-93d9-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:2592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:372e5624-7972-11ec-93d9-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:2593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir disoproxil targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:372e7eec-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir disoproxil is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:372ea7a0-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenoxicam targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:372ed108-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenoxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.943']} DrugCentral uuid:372efe80-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.67']} DrugCentral uuid:372f2c0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.628']} DrugCentral uuid:372f598e-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.388']} DrugCentral uuid:372f8922-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:372fb69a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:372fe426-7972-11ec-93d9-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:37300d48-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.662']} DrugCentral uuid:37303ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P52020 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:37306838-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2598 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbutaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:373095c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2598 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbutaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3730c3f0-7972-11ec-93d9-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.373']} DrugCentral uuid:3730f140-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:37311ec2-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.895']} DrugCentral uuid:37314dd4-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.433']} DrugCentral uuid:37317bf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:3731aaea-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.216']} DrugCentral uuid:3731d86c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.599']} DrugCentral uuid:37320666-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.632']} DrugCentral uuid:373233e8-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.438']} DrugCentral uuid:37326174-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:37328fc8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:3732bd4a-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.862']} DrugCentral uuid:3732eac2-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.338']} DrugCentral uuid:37331948-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.511']} DrugCentral uuid:37334706-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.718']} DrugCentral uuid:3733749c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.504']} DrugCentral uuid:3733a20a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:3733d004-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.362']} DrugCentral uuid:3733fd86-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:37342b12-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:37345484-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.666']} DrugCentral uuid:37348206-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.963']} DrugCentral uuid:3734af7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3734dd00-7972-11ec-93d9-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37350c94-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.612']} DrugCentral uuid:37353a0c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.102']} DrugCentral uuid:3735678e-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.389']} DrugCentral uuid:3735957e-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:3735c2ec-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:3735f06e-7972-11ec-93d9-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37361eb8-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.874']} DrugCentral uuid:37364e56-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.687']} DrugCentral uuid:37367c14-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:3736a978-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:3736d7d6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.719']} DrugCentral uuid:3737053a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:373732c6-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:373760de-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:37378e74-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:3737bc0a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:3737e9a0-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:3738186c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:373845ee-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:3738737a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.693']} DrugCentral uuid:3738a278-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.448']} DrugCentral uuid:3738d022-7972-11ec-93d9-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3738fdb8-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.213']} DrugCentral uuid:37392b30-7972-11ec-93d9-0242ac110002 UniProtKB:P51589 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Enzyme (Cytochrome P450 2J2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:37395934-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:373986a2-7972-11ec-93d9-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3739b406-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.734']} DrugCentral uuid:3739e23c-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:373a0fc8-7972-11ec-93d9-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:373a45e2-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:373a45e2-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:373a45e2-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:373a90c4-7972-11ec-93d9-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:373abe28-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:373aebaa-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:373b19a4-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:373b4726-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:373b749e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:373ba2d4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:373bd088-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:373bfe14-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:373c2bbe-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:373c5af8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:373c8870-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:373cb746-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:373ce54a-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:373d12ea-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:373d4076-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:373d6e0c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:373d9c38-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:373dc9d8-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:373df732-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:373e25f4-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:373e5376-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:373e8102-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:373eae84-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terodiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:373edd5a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.087']} DrugCentral uuid:373f0af0-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:373f3886-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:373f66bc-7972-11ec-93d9-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:373f9452-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:373fc260-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:2606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testolactone is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:373ff140-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:37401efe-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:37404c8a-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:37407a02-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3740a7e8-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3740d574-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:374102f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3741310e-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:37415ea4-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.599']} DrugCentral uuid:37418c26-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3741bebc-7972-11ec-93d9-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3741bebc-7972-11ec-93d9-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3741f9d6-7972-11ec-93d9-0242ac110002 UniProtKB:O35627 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Nuclear hormone receptor (Constitutive androstane receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3742276c-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone undecanoate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:3742502a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:37427e1a-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:3742ab92-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:3742d928-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3743075e-7972-11ec-93d9-0242ac110002 UniProtKB:Q27963 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:37433648-7972-11ec-93d9-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:37436550-7972-11ec-93d9-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:37439cfa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:37439cfa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:37439cfa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:3743e5f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3744134c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.153']} DrugCentral uuid:37444146-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.011']} DrugCentral uuid:37446ed2-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.766']} DrugCentral uuid:37449c86-7972-11ec-93d9-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3744ca80-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel protein type 8 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3744f816-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:37452598-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.499']} DrugCentral uuid:37455306-7972-11ec-93d9-0242ac110002 UniProtKB:Q00194 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (cGMP-gated cation channel alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:37458a7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:37458a7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:37458a7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3745dc40-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3745dc40-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3745dc40-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3746251a-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:2611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:37464de2-7972-11ec-93d9-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:2611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:3746768c-7972-11ec-93d9-0242ac110002 UniProtKB:P29475 biolink:molecularly_interacts_with DrugCentral:2612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sapropterin targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.95']} DrugCentral uuid:3746a4b8-7972-11ec-93d9-0242ac110002 UniProtKB:P00439 biolink:molecularly_interacts_with DrugCentral:2612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sapropterin is activator of Enzyme (Phenylalanine-4-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3746d352-7972-11ec-93d9-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:374700d4-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:37472e60-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:37475de0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:37478b62-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:3747b8d0-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.432']} DrugCentral uuid:3747e6a2-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3748141a-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:37484188-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:37486f00-7972-11ec-93d9-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:37489d5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.393']} DrugCentral uuid:3748cae0-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3748f880-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.85']} DrugCentral uuid:3749288c-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:37495cbc-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:37498a66-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3749b874-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:3749e5ec-7972-11ec-93d9-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:374a13aa-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:374a40e6-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:374a6f30-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:374a9cbc-7972-11ec-93d9-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:374aca34-7972-11ec-93d9-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:374af900-7972-11ec-93d9-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:374b2682-7972-11ec-93d9-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:374b595e-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:374b595e-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:374b94f0-7972-11ec-93d9-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:374bcf1a-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:374bcf1a-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:374bcf1a-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:374bcf1a-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:374c2e60-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:374c2e60-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:374c2e60-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:374c76fe-7972-11ec-93d9-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:374ca494-7972-11ec-93d9-0242ac110002 UniProtKB:Q60614 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:374cd37e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS9 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Unclassified (Transmembrane domain-containing protein TMIGD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:374d01a0-7972-11ec-93d9-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.22']} DrugCentral uuid:374d2f18-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:374d5d12-7972-11ec-93d9-0242ac110002 UniProtKB:Q09508 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) DrugCentral uuid:374d85bc-7972-11ec-93d9-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:374db352-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:374de0c0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AE18 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:374e0ee2-7972-11ec-93d9-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:374e44ca-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e44ca-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e44ca-7972-11ec-93d9-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e9f92-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e9f92-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e9f92-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e9f92-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e9f92-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e9f92-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374e9f92-7972-11ec-93d9-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:374f118e-7972-11ec-93d9-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:374f3a92-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:374f6800-7972-11ec-93d9-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:374fd52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:3750af4e-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:3750dcda-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37510ade-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:37513856-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:375165d8-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:37519378-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3751c1ae-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3751ef44-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37521de8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37524df4-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:37527b80-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:3752a416-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:3752ccc0-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:3752f5c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:37531fc2-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:3753489e-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:37537724-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3753a46a-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.221']} DrugCentral uuid:3753d1ec-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.912']} DrugCentral uuid:3753ff82-7972-11ec-93d9-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:37542aa2-7972-11ec-93d9-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:37545374-7972-11ec-93d9-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) DrugCentral uuid:37547c32-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:3754aa22-7972-11ec-93d9-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) DrugCentral uuid:3754d2cc-7972-11ec-93d9-0242ac110002 UniProtKB:P00492 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) DrugCentral uuid:3754fc0c-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.258']} DrugCentral uuid:37552984-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.792']} DrugCentral uuid:375557ce-7972-11ec-93d9-0242ac110002 UniProtKB:P26281 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Kinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.75']} DrugCentral uuid:37558dca-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:37558dca-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:37558dca-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37560fde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:37570a60-7972-11ec-93d9-0242ac110002 UniProtKB:Q63734 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is gating inhibitor of Ion channel (Potassium voltage-gated channel subfamily C member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:37573864-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioproperazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.347']} DrugCentral uuid:375765dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioproperazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:3757934a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:3757bd20-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3757ebf6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3758196e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.872']} DrugCentral uuid:37584718-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:37587508-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3758a262-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3758cfe4-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.813']} DrugCentral uuid:3758fdfc-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:37592b92-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:37595900-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:375987ae-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3759b8fa-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3759e69a-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:375a1430-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:375a4216-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.466']} DrugCentral uuid:375a6fa2-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:375a9d1a-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:375acb78-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:375af904-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.866']} DrugCentral uuid:375b267c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:375b53fe-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.569']} DrugCentral uuid:375b8414-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:375bb182-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.595']} DrugCentral uuid:375bdf04-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:375c0ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:375c3a76-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:375c67c6-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:375c9548-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:375cc37e-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.126']} DrugCentral uuid:375cf0ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.774']} DrugCentral uuid:375d1e6e-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.751']} DrugCentral uuid:375d4d62-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:375d7af8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.686']} DrugCentral uuid:375da884-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:375dd688-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:375e05ae-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:375e334e-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:375e60b2-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.712']} DrugCentral uuid:375e906e-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.531']} DrugCentral uuid:375ebde6-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.195']} DrugCentral uuid:375eeb5e-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.297']} DrugCentral uuid:375f1ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:375f4860-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:375f75e2-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.284']} DrugCentral uuid:375fa364-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:375fd15e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:375fff08-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:37602c8a-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:37605ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:37608838-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3760b5ce-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3760f692-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3760f692-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3760f692-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3760f692-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3760f692-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:37616fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:37616fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:37616fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:37616fe6-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3761cff4-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3761cff4-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3761cff4-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:37622a62-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:37622a62-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:37622a62-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:37622a62-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:37622a62-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:376296a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:376296a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:376296a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3762e9e8-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3762e9e8-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3762e9e8-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:376332a4-7972-11ec-93d9-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:376361c0-7972-11ec-93d9-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiotepa is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:37638f4c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.292']} DrugCentral uuid:3763bce2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.347']} DrugCentral uuid:3763eaf0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:3764187c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:376445f4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:3764738a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3764a3f0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:3764d410-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.681']} DrugCentral uuid:376501ba-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.817']} DrugCentral uuid:37653090-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.94']} DrugCentral uuid:37655e30-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:37658ba8-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.412']} DrugCentral uuid:3765b92a-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.583']} DrugCentral uuid:3765e774-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:37661500-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.386']} DrugCentral uuid:37664282-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.585']} DrugCentral uuid:37667234-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:37669fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:3766cdba-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:3766fbc8-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.318']} DrugCentral uuid:3767294a-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:376756c2-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.181']} DrugCentral uuid:37678458-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:3767b298-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.693']} DrugCentral uuid:3767e056-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:37680dce-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:37683ccc-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.442']} DrugCentral uuid:37686ab2-7972-11ec-93d9-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor alpha) DrugCentral uuid:37689384-7972-11ec-93d9-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3768c0fc-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:3768ef0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:37691c8c-7972-11ec-93d9-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:376949e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Unclassified (THAP domain-containing protein 1) DrugCentral uuid:37697330-7972-11ec-93d9-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3769a1a2-7972-11ec-93d9-0242ac110002 UniProtKB:P40926 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Enzyme (Malate dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:3769cf24-7972-11ec-93d9-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine is inhibitor of Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3769fe0e-7972-11ec-93d9-0242ac110002 UniProtKB:P23978 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:376a2c76-7972-11ec-93d9-0242ac110002 UniProtKB:P31648 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:376a5a0c-7972-11ec-93d9-0242ac110002 UniProtKB:P31651 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent betaine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:376a901c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:376a901c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:376a901c-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:376ae1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:376ae1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:376ae1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:376b2a4a-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tianeptine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:376b5880-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.077']} DrugCentral uuid:376b85ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.108']} DrugCentral uuid:376bb37a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.756']} DrugCentral uuid:376be1d8-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:376c0f64-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiaprofenic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:376c3cd2-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiaprofenic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:376c6a40-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.317']} DrugCentral uuid:376c983a-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:376cc5da-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:376ceec0-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:376d1850-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:376d45aa-7972-11ec-93d9-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Enzyme (Steryl-sulfatase) DrugCentral uuid:376d6e72-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.123']} DrugCentral uuid:376d9bf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.542']} DrugCentral uuid:376dcc1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:376e0ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:376e0ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:376e0ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:376e0ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:376e0ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:376e0ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:376e0ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:376e7f24-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:376eac7e-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:376ed9ec-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:376f0840-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.747']} DrugCentral uuid:376f35b8-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.857']} DrugCentral uuid:376f6330-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.767']} DrugCentral uuid:376f9418-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.201']} DrugCentral uuid:376fc456-7972-11ec-93d9-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:376ff1d8-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:37701fa0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine is antagonist of GPCR (P2Y purinoceptor 12) DrugCentral uuid:37704868-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.175']} DrugCentral uuid:377075ea-7972-11ec-93d9-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3770a36c-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:3770d18e-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:3770ff24-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tienilic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.494']} DrugCentral uuid:37712c7e-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tilidine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:37715afa-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:2664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiliquinol targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:37718868-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) DrugCentral uuid:3771b11c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13488 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (V-type proton ATPase 116 kDa subunit a isoform 3) DrugCentral uuid:3771d9ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3772090a-7972-11ec-93d9-0242ac110002 UniProtKB:P50281 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Matrix metalloproteinase-14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:377236a0-7972-11ec-93d9-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:37726422-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tinoridine is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.987']} DrugCentral uuid:3772924e-7972-11ec-93d9-0242ac110002 UniProtKB:O69638 biolink:molecularly_interacts_with DrugCentral:2673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiocarlide targets Enzyme (Epoxide hydrolase EphE; Hydrolase, alpha/beta hydrolase fold family) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3772bfda-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2675 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:3772e898-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:2675 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:37731624-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiopronin targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:37734540-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:377372b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:3773a058-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11.1']} DrugCentral uuid:3773ce34-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:3773fba2-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:3774291a-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:377456a6-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:377484b4-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3774b22c-7972-11ec-93d9-0242ac110002 UniProtKB:F1PT23 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3774e062-7972-11ec-93d9-0242ac110002 UniProtKB:F1PWR7 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.94']} DrugCentral uuid:37750f88-7972-11ec-93d9-0242ac110002 UniProtKB:F1PGZ2 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:37753d5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiracizine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:37756f1e-7972-11ec-93d9-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:2680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirofiban is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:37756f1e-7972-11ec-93d9-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:2680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirofiban is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:3775aab0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3775d828-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:3776024e-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:37762fc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:37765f28-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:37768caa-7972-11ec-93d9-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:3776ba0e-7972-11ec-93d9-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:2684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tobramycin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.824']} DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:37770e78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:3777a1a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2693 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofisopam targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3777cef8-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2693 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofisopam targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3777fc52-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.292']} DrugCentral uuid:37782ede-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) DrugCentral uuid:37782ede-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) DrugCentral uuid:37786386-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3778911c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3778c01a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3778ed9c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:37791b46-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:377951f6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:377951f6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:377951f6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3779a32c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3779a32c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3779a32c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3779edaa-7972-11ec-93d9-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:377a1b36-7972-11ec-93d9-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:377a4cfa-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:377a4cfa-7972-11ec-93d9-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:377a8954-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.69']} DrugCentral uuid:377ab6c2-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:377ae57a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:377b12e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13118 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Nuclear other (Krueppel-like factor 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:377b4150-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:377b6edc-7972-11ec-93d9-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.569']} DrugCentral uuid:377b9c54-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:377bca58-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:377bf7bc-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:377c2534-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:377c52ac-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:377c810a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:377cae78-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:377cdbf0-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:377d09cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:377d3758-7972-11ec-93d9-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:377d64c6-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.667']} DrugCentral uuid:377d92a2-7972-11ec-93d9-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:2701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolonium targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:377dc024-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:2701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolonium targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:377ded9c-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:377e1c2c-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:377e4c88-7972-11ec-93d9-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:377e7a14-7972-11ec-93d9-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:377ea7b4-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:377ed5fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.253']} DrugCentral uuid:377f039e-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:377f313e-7972-11ec-93d9-0242ac110002 UniProtKB:P70634 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Unclassified (SMR1-alpha3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:377f5ec0-7972-11ec-93d9-0242ac110002 UniProtKB:P70635 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Unclassified (BetaB2-crystallin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.474']} DrugCentral uuid:377f8cd8-7972-11ec-93d9-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:377fba5a-7972-11ec-93d9-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:377fe7f0-7972-11ec-93d9-0242ac110002 UniProtKB:P80276 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:37801694-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3780440c-7972-11ec-93d9-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3780715c-7972-11ec-93d9-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:37809fa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q91WR5 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldo-keto reductase family 1 member C21) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:3780cd28-7972-11ec-93d9-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3780fad2-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat is inhibitor of Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.509']} DrugCentral uuid:37812840-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3781564e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:378183ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.57']} DrugCentral uuid:3781b2f6-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:3781e136-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:37820f6c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:37823ce4-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:37826a7a-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:378299fa-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3782c7c2-7972-11ec-93d9-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:3782f56c-7972-11ec-93d9-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:3783238e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:37834c7e-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:37837528-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:37839dfa-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3783cdde-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3783fba6-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3784295a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3784579a-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:37848526-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3784b2b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3784e098-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:37850e60-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:37853c00-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:378569a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:3785998e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:3785c724-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:3785f4d8-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:378622e6-7972-11ec-93d9-0242ac110002 UniProtKB:P27139 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:37865086-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:37867e12-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.63']} DrugCentral uuid:3786aba8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:3786d9ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3787074c-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:378735dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:37876480-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:37879202-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3787bf8e-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3787ee1e-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:37881bb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:37884a94-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:37887820-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3788a660-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3788d432-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:37890a42-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:37890a42-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:37890a42-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:37894ff2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:37894ff2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:37899c3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:37899c3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:37899c3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:37899c3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:37899c3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:378a0186-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:378a0186-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:378a0186-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:378a0186-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:378a4d94-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:378a7bd4-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:378aa96a-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.818']} DrugCentral uuid:378ad6b0-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:378b0162-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:378b2a34-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:378b52e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:378b7b92-7972-11ec-93d9-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:378ba4c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan is inhibitor of Enzyme (DNA topoisomerase I, mitochondrial) DrugCentral uuid:378bcd86-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.58']} DrugCentral uuid:378bfb12-7972-11ec-93d9-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:378c289e-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:378c56ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:378c844c-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:378cb1c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q04750 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (DNA topoisomerase I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:378ce108-7972-11ec-93d9-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:378d0e62-7972-11ec-93d9-0242ac110002 UniProtKB:P9WIQ1 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (UDP-galactopyranose mutase) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:378d3bee-7972-11ec-93d9-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 torsemide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:378d6966-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:378d976a-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene is modulator of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:378dc172-7972-11ec-93d9-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets Nuclear hormone receptor (Estrogen-related receptor gamma) DrugCentral uuid:378dea44-7972-11ec-93d9-0242ac110002 UniProtKB:Q05320 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets Unclassified (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:378e18a2-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:378e470a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:378e7464-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:378ea1be-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:378ed09e-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:378efe0c-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:378f2b70-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:378f5974-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trandolapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:378f870a-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranexamic acid is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:378fb5b8-7972-11ec-93d9-0242ac110002 UniProtKB:O60760 biolink:molecularly_interacts_with DrugCentral:2714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranilast targets Enzyme (Hematopoietic prostaglandin D synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:378fe3e4-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.229']} DrugCentral uuid:37901152-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.225']} DrugCentral uuid:37903efc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:37906c88-7972-11ec-93d9-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:37909c30-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3790c9a8-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3790f81a-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37912718-7972-11ec-93d9-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:379154b8-7972-11ec-93d9-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.88']} DrugCentral uuid:3791823a-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:3791afda-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3791ddc0-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:37920b4c-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:379238f6-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:379268f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NB78 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Lysine-specific histone demethylase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:37929684-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3792c41a-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 travoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:3792f282-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:2716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 travoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:37932004-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.428']} DrugCentral uuid:37934e3a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:37937bb2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:3793a9c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.033']} DrugCentral uuid:3793d760-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:379404f6-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:37943502-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:379463c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:3794916e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:3794bfcc-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:3794ed8a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:37951b20-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.749']} DrugCentral uuid:379548c0-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.551']} DrugCentral uuid:379576b0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3795a43c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.896']} DrugCentral uuid:3795d1be-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:37960012-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.483']} DrugCentral uuid:37962d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:37965b0c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:379688a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3796b6d8-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.153']} DrugCentral uuid:3796e450-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:379711e6-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:37973fe0-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.081']} DrugCentral uuid:37976d80-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.083']} DrugCentral uuid:37979af8-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:3797c85c-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:3797f714-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:37982496-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:37985240-7972-11ec-93d9-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:379880a8-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3798af74-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3798dd1e-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:37990b36-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:379938c2-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:37996658-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:379993f8-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.642']} DrugCentral uuid:3799c36e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:3799f12c-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:379a1eae-7972-11ec-93d9-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Enzyme (11-cis retinol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:379a4c9e-7972-11ec-93d9-0242ac110002 UniProtKB:P35398 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:379a7a20-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:379aa7ac-7972-11ec-93d9-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:379ad54c-7972-11ec-93d9-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:379b04cc-7972-11ec-93d9-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:379b32ee-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:379b607a-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:379b8f3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q92753 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is antagonist of Nuclear hormone receptor (Nuclear receptor ROR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.82']} DrugCentral uuid:379bbcb4-7972-11ec-93d9-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:379bea4a-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:379c186c-7972-11ec-93d9-0242ac110002 UniProtKB:P40220 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:379c45da-7972-11ec-93d9-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:379c738e-7972-11ec-93d9-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:379ca124-7972-11ec-93d9-0242ac110002 UniProtKB:P62965 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:379ccf28-7972-11ec-93d9-0242ac110002 UniProtKB:P22935 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:379cfdae-7972-11ec-93d9-0242ac110002 UniProtKB:P11416 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:379d2b30-7972-11ec-93d9-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:379d59fc-7972-11ec-93d9-0242ac110002 UniProtKB:P22605 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:379d8774-7972-11ec-93d9-0242ac110002 UniProtKB:P18911 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:379db50a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:379de296-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:379e1090-7972-11ec-93d9-0242ac110002 UniProtKB:P49116 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear other (Nuclear receptor subfamily 2 group C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:379e3e44-7972-11ec-93d9-0242ac110002 UniProtKB:Q13526 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Unclassified (Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:379e6bd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear other (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:379e99de-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.27']} DrugCentral uuid:379ec760-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:379ef514-7972-11ec-93d9-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:379f23b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:379f5130-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.76']} DrugCentral uuid:379f8736-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:379f8736-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:379f8736-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:379fe136-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:379fe136-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:379fe136-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:379fe136-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:379fe136-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37a05ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:37a05ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:37a05ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:37a05ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:37a05ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:37a05ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:37a0d79e-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:37a0d79e-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:37a0d79e-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:37a124c4-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:37a15264-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone targets Cytosolic other (Annexin A1) DrugCentral uuid:37a17b2c-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:37a1a476-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:37a1d1e4-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide targets Cytosolic other (Annexin A1) DrugCentral uuid:37a1fab6-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:37a22874-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone diacetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:37a251fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Transporter (Solute carrier family 12 member 1) DrugCentral uuid:37a27b6c-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:37a2a8f8-7972-11ec-93d9-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.436']} DrugCentral uuid:37a2d79c-7972-11ec-93d9-0242ac110002 UniProtKB:P08311 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Cathepsin G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:37a30500-7972-11ec-93d9-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:37a33b1a-7972-11ec-93d9-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37a33b1a-7972-11ec-93d9-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37a33b1a-7972-11ec-93d9-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37a3846c-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:37a3b1ee-7972-11ec-93d9-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.879']} DrugCentral uuid:37a3df84-7972-11ec-93d9-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:37a41634-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:37a41634-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:37a41634-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:37a46918-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:37a46918-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:37a46918-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:37a4bb5c-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:37a4bb5c-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:37a4bb5c-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:37a50cce-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:37a50cce-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:37a50cce-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:37a55ea4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:37a55ea4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:37a55ea4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:37a5b156-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:37a5b156-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:37a5b156-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a63a5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a7720c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37a84cd6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:37a84cd6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:37a84cd6-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:37a89fb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:37a89fb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:37a89fb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:37a8f30c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37a8f30c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37a8f30c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37a94456-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:37a94456-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:37a94456-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:37a99622-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37a99622-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37a99622-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:37a9ded4-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:37aa0c6a-7972-11ec-93d9-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7']} DrugCentral uuid:37aa3bae-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:37aa6944-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:37aa96d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:37aac4ca-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:37aaf30a-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:37ab2096-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:37ab4e22-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:37ab7c6c-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:37abaa0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:37abd8a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:37ac06fa-7972-11ec-93d9-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclabendazole targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ac7392-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:37ad5032-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tridihexethyl is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:37ad78fa-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tridihexethyl is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:37ada1cc-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:37add00c-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:37adfde8-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:37ae2b74-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:37ae5914-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37ae870e-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:37aeb4a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.31']} DrugCentral uuid:37aee244-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:37af1066-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:37af3f0a-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:37af6c8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:37af9ae0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:37afc90c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:37aff6ac-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.841']} DrugCentral uuid:37b02442-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:37b0525a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:37b07fe6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:37b0ada4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:37b0dbee-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:37b109ac-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.022']} DrugCentral uuid:37b13756-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:37b164f6-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:37b19354-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.849']} DrugCentral uuid:37b1c0e0-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.536']} DrugCentral uuid:37b1ee80-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:37b21c70-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.786']} DrugCentral uuid:37b24a92-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.251']} DrugCentral uuid:37b27828-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:37b2a5c8-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:37b2d3d6-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.407']} DrugCentral uuid:37b30176-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:37b33786-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:37b33786-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:37b33786-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:37b386a0-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:37b3b436-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.27']} DrugCentral uuid:37b3e230-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:37b40fe4-7972-11ec-93d9-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:37b43d52-7972-11ec-93d9-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:37b46ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P06760 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Beta-glucuronidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:37b498f6-7972-11ec-93d9-0242ac110002 UniProtKB:P00697 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Lysozyme C-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:37b4c664-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:37b4f404-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:37b522da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY08 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Emopamil-binding protein-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:37b558ea-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:37b558ea-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:37b558ea-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:37b5aa84-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37b5aa84-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37b5aa84-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37b5fc0a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:37b5fc0a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:37b5fc0a-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:37b644f8-7972-11ec-93d9-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:37b6732e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:37b6a0ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:37b6ce6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:37b6fd30-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.456']} DrugCentral uuid:37b72abc-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:37b7596a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:37b786e2-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:37b7b4dc-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:37b7e2a4-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:37b8103a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:37b83ea2-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:37b86c56-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:37b899d8-7972-11ec-93d9-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:37b8c85e-7972-11ec-93d9-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:2743 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluridine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:37b8f5cc-7972-11ec-93d9-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:2743 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluridine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.01']} DrugCentral uuid:37b923ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:37b95300-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:37b98104-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.73']} DrugCentral uuid:37b9ae72-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:37b9dbf4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:37ba0a2a-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.99']} DrugCentral uuid:37ba37a2-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.611']} DrugCentral uuid:37ba6538-7972-11ec-93d9-0242ac110002 UniProtKB:P26439 biolink:molecularly_interacts_with DrugCentral:2746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilostane is inhibitor of Enzyme (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2) DrugCentral uuid:37ba8e14-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alimemazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:37baba7e-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alimemazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:37bae9ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:2750 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetazidine targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:37bb1780-7972-11ec-93d9-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethadione is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:37bb40a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:37bb6960-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) DrugCentral uuid:37bb923c-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:37bbbfd2-7972-11ec-93d9-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:37bbf326-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:37bbf326-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:37bc27a6-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:37bc5546-7972-11ec-93d9-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:37bc853e-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:37bcb2de-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:37bce042-7972-11ec-93d9-0242ac110002 UniProtKB:Q27713 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:37bd0eb4-7972-11ec-93d9-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:37bd3c4a-7972-11ec-93d9-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:37bd69ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:37bd97a8-7972-11ec-93d9-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:37bdc5ac-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:37bdf338-7972-11ec-93d9-0242ac110002 UniProtKB:P07807 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:37be209c-7972-11ec-93d9-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:37be4edc-7972-11ec-93d9-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:37be7c5e-7972-11ec-93d9-0242ac110002 UniProtKB:O30463 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:37bea9e0-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:37bed7ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:37bf0624-7972-11ec-93d9-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:37bf33a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q27783 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:37bf6146-7972-11ec-93d9-0242ac110002 UniProtKB:P04174 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:37bf8f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q59487 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:37bfbe70-7972-11ec-93d9-0242ac110002 UniProtKB:Q81R22 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:37bfec1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q27552 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:37c01afa-7972-11ec-93d9-0242ac110002 UniProtKB:P00382 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:37c049e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:37c07784-7972-11ec-93d9-0242ac110002 UniProtKB:Q54801 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:37c0a524-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UUP5 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:37c0d314-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:37c100be-7972-11ec-93d9-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:37c1297c-7972-11ec-93d9-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:37c157ee-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:37c18584-7972-11ec-93d9-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:37c1b31a-7972-11ec-93d9-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:37c1e0a6-7972-11ec-93d9-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:37c21184-7972-11ec-93d9-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:37c23efc-7972-11ec-93d9-0242ac110002 UniProtKB:P07807 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:37c26c6a-7972-11ec-93d9-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:37c29a6e-7972-11ec-93d9-0242ac110002 UniProtKB:O30463 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:37c2c7e6-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:37c2f572-7972-11ec-93d9-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:37c323d0-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.827']} DrugCentral uuid:37c35166-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:37c37f06-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:37c3acb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.423']} DrugCentral uuid:37c3dbcc-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:37c4094e-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.133']} DrugCentral uuid:37c436ee-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.909']} DrugCentral uuid:37c464fc-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:37c49288-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:37c4c15e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:37c4eef4-7972-11ec-93d9-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:37c51de8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tripelennamine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:37c54b7e-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triprolidine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:37c57914-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triprolidine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.9']} DrugCentral uuid:37c5a826-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.208']} DrugCentral uuid:37c5d5d0-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.078']} DrugCentral uuid:37c60370-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.531']} DrugCentral uuid:37c63188-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.013']} DrugCentral uuid:37c6604a-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:37c68dc2-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:37c6bb3a-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:37c6e966-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:37c716d4-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Aldose reductase) DrugCentral uuid:37c73f9c-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:37c76e40-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:37c79ef6-7972-11ec-93d9-0242ac110002 UniProtKB:P54840 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Glycogen [starch] synthase, liver) DrugCentral uuid:37c7c7c8-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.528']} DrugCentral uuid:37c7f54a-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.691']} DrugCentral uuid:37c82344-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.907']} DrugCentral uuid:37c850bc-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:37c87e7a-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:37c8aca6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:37c8da1e-7972-11ec-93d9-0242ac110002 UniProtKB:P19224 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (UDP-glucuronosyltransferase 1-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:37c907b4-7972-11ec-93d9-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:37c9352c-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:37c9654c-7972-11ec-93d9-0242ac110002 UniProtKB:P39654 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Polyunsaturated fatty acid lipoxygenase ALOX15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:37c992ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2769 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troleandomycin is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:37c9c06e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:37c9ee54-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:37ca1bea-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:37ca496c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:37ca77a2-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:37caa542-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:37cad2ce-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:37cb005a-7972-11ec-93d9-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:37cb2fe4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:37cb5d7a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:37cb8b10-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.606']} DrugCentral uuid:37cbb9c8-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:37cbe768-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:37cc14fe-7972-11ec-93d9-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:37cc428a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:37cc70fc-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:37cc9e92-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:37cccc28-7972-11ec-93d9-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:37ccfc70-7972-11ec-93d9-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:37cd2a1a-7972-11ec-93d9-0242ac110002 UniProtKB:P49582 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:37cd57ba-7972-11ec-93d9-0242ac110002 UniProtKB:O70212 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:37cd8a28-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:37cd8a28-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:37cdcab0-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:37cdcab0-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:37ce12c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:37ce12c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:37ce12c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:37ce12c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:37ce6e02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:37ce6e02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:37cea94e-7972-11ec-93d9-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:37ceda04-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:37cf0812-7972-11ec-93d9-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:37cf359e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:37cf5f24-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium is antagonist of GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:37cf87e2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:37cfb082-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:37cfd94a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.306']} DrugCentral uuid:37d0073a-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.395']} DrugCentral uuid:37d038fe-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:37d038fe-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:37d07206-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:37d07206-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:37d0a85c-7972-11ec-93d9-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan is allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:37d0d5d4-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:37d10338-7972-11ec-93d9-0242ac110002 UniProtKB:Q6DWJ6 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan is agonist of GPCR (Probable G-protein coupled receptor 139) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:37d1315a-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:37d15ebe-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:37d18c22-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:37d1bac6-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:37d1e8ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:37d2161a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2S1 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:37d2439c-7972-11ec-93d9-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:37d27222-7972-11ec-93d9-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:37d2a044-7972-11ec-93d9-0242ac110002 UniProtKB:Q401N2 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Zinc-activated ligand-gated ion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:37d2cee8-7972-11ec-93d9-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:37d2fc88-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:37d32ab4-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:37d35836-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:37d385a4-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:37d3b3bc-7972-11ec-93d9-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:37d3e576-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:37d3e576-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:37d4291e-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:37d4291e-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:37d4291e-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:37d47a72-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:37d47a72-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:37d4ba00-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:37d4ba00-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:37d4fa60-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:37d4fa60-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:37d539e4-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:37d539e4-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:37d583a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:37d583a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:37d583a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:37d583a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:37d5de62-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:37d5de62-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:37d61ada-7972-11ec-93d9-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d68768-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37d78424-7972-11ec-93d9-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:37d7b192-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tulobuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:37d7df32-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tulobuterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:37d80a52-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:37d837c0-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['2.7']} DrugCentral uuid:37d86538-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:37d89346-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:37d8c096-7972-11ec-93d9-0242ac110002 UniProtKB:H9TVJ1 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (TyR1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37d92540-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:37da038e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:37da3106-7972-11ec-93d9-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyrosine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:37da5f14-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:37da8c82-7972-11ec-93d9-0242ac110002 UniProtKB:P15144 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:37dabaea-7972-11ec-93d9-0242ac110002 UniProtKB:P28838 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:37dae902-7972-11ec-93d9-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:37db1954-7972-11ec-93d9-0242ac110002 UniProtKB:P15145 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:37db46d6-7972-11ec-93d9-0242ac110002 UniProtKB:O96935 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (M1 family aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:37db7476-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VCT3 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:37dba2c0-7972-11ec-93d9-0242ac110002 UniProtKB:P97629 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Leucyl-cystinyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:37dbd196-7972-11ec-93d9-0242ac110002 UniProtKB:O09175 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:37dbff22-7972-11ec-93d9-0242ac110002 UniProtKB:P00727 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:37dc2d4e-7972-11ec-93d9-0242ac110002 UniProtKB:P97449 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:37dc5ad0-7972-11ec-93d9-0242ac110002 UniProtKB:Q01693 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Bacterial leucyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:37dc8870-7972-11ec-93d9-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:37dcb5de-7972-11ec-93d9-0242ac110002 UniProtKB:P15684 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:37dce3d8-7972-11ec-93d9-0242ac110002 UniProtKB:P55786 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Puromycin-sensitive aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:37dd1178-7972-11ec-93d9-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:37dd3f18-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ08 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Endoplasmic reticulum aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:37dd6dee-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:37dd9b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:37ddc92e-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:37ddf6c4-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:37de24f0-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Enzyme (Aldo-keto reductase family 1 member C2) DrugCentral uuid:37de4d9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol is agonist of Nuclear hormone receptor (Bile acid receptor) DrugCentral uuid:37de7662-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:37dea420-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:37ded1ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:37deff4c-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valaciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:37df2828-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:37df5a14-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:37df878c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.537']} DrugCentral uuid:37dfb518-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:37dfe312-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.37']} DrugCentral uuid:37e0109e-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:37e03e3e-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:37e06bc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:37e09a28-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:37e0c7be-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:37e0f554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:37e12416-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:37e1524c-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:37e17fd8-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:37e1ade6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:37e1db7c-7972-11ec-93d9-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:37e20908-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:37e236bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:37e264ac-7972-11ec-93d9-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:37e293aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:37e2c15e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:37e2f0ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:37e31b36-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:37e34462-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:37e36da2-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:37e3971e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:37e3c112-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:37e3ea34-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:37e41338-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:37e43d36-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:37e46662-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:37e48f98-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:37e4b9f0-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:37e4e34e-7972-11ec-93d9-0242ac110002 UniProtKB:O78749 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Cytochrome c oxidase subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:37e50c3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:37e53556-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:37e55edc-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:37e587f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:37e5b0f8-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:37e5da10-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:37e603fa-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:37e62d30-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:37e65652-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:37e67f74-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:37e6aa9e-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valganciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:37e6cfec-7972-11ec-93d9-0242ac110002 UniProtKB:P51649 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid is inhibitor of Enzyme (Succinate-semialdehyde dehydrogenase, mitochondrial) DrugCentral uuid:37e6f4a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:37e71da8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:37e74738-7972-11ec-93d9-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:37e77046-7972-11ec-93d9-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:37e7995e-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:37e7c2f8-7972-11ec-93d9-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:37e7ecec-7972-11ec-93d9-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:37e815d2-7972-11ec-93d9-0242ac110002 UniProtKB:P35504 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (UDP-glucuronosyltransferase 1-5) DrugCentral uuid:37e83a8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5RJP0 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase-related protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:37e864c4-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:2805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valrubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:37e889a4-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:37e8b3fc-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:37e8dd0a-7972-11ec-93d9-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:37e90a50-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:37e90a50-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:37e93f66-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:37e96892-7972-11ec-93d9-0242ac110002 UniProtKB:Q06241 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets Enzyme (D-alanyl-D-alanine dipeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:37e991dc-7972-11ec-93d9-0242ac110002 UniProtKB:P17443 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets Enzyme (UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:37e9bb8a-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:37e9e484-7972-11ec-93d9-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:37ea118e-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:37ea118e-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:37ea4d3e-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:37ea4d3e-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:37ea86a0-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:37ea86a0-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:37eabfa8-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:37eabfa8-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:37eaf93c-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:37eaf93c-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:37eb3258-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:37eb3258-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:37eb6d4a-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:37eb6d4a-7972-11ec-93d9-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:37eba670-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:37eba670-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:37ebe72a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:37ebe72a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:37ebe72a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:37ebe72a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:37ec3be4-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:37ec3be4-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:37ec7cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:37ec7cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:37ec7cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:37ec7cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:37eccaa0-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:37ecf39a-7972-11ec-93d9-0242ac110002 UniProtKB:P16499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.465']} DrugCentral uuid:37ed1dfc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:37ed47a0-7972-11ec-93d9-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.041']} DrugCentral uuid:37ed7126-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:37ed9a52-7972-11ec-93d9-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:37edc360-7972-11ec-93d9-0242ac110002 UniProtKB:O76083 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:37edf18c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:37edf18c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:37ee332c-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:37ee332c-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:37ee332c-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:37ee332c-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:37ee8494-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:37ee8494-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:37eeb9e6-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.59']} DrugCentral uuid:37eee330-7972-11ec-93d9-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:37ef0c66-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:37ef3632-7972-11ec-93d9-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.78']} DrugCentral uuid:37ef5f4a-7972-11ec-93d9-0242ac110002 UniProtKB:P32307 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:37ef8844-7972-11ec-93d9-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.93']} DrugCentral uuid:37efb242-7972-11ec-93d9-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:37efdb96-7972-11ec-93d9-0242ac110002 UniProtKB:P48044 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:37f004a4-7972-11ec-93d9-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:37f02dbc-7972-11ec-93d9-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:37f05b2a-7972-11ec-93d9-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:37f05b2a-7972-11ec-93d9-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:37f09072-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:37f0b96c-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:37f0e27a-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:37f10ff2-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:37f10ff2-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:37f146fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:37f146fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:37f146fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:37f18e1e-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:37f18e1e-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:37f1c14a-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:37f1c14a-7972-11ec-93d9-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:37f1fc0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:37f1fc0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:37f1fc0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:37f1fc0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:37f24b74-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.051']} DrugCentral uuid:37f27496-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.975']} DrugCentral uuid:37f29dc2-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.652']} DrugCentral uuid:37f2c766-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:37f2f074-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.554']} DrugCentral uuid:37f319aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:37f342d6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:37f36df6-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:37f3972c-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:37f3c0d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:37f3e9f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:37f41346-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:37f437fe-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:37f4612a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:37f48a42-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:37f4b3fa-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:37f4dd1c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:37f50648-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.763']} DrugCentral uuid:37f5314a-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:37f55d82-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:37f5887a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:37f5b1c4-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.201']} DrugCentral uuid:37f5db4a-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.594']} DrugCentral uuid:37f6044e-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:37f62d2a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:37f65660-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:37f6800e-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.88']} DrugCentral uuid:37f6a8fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:37f6d202-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:37f6f6a6-7972-11ec-93d9-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (G protein-activated inward rectifier potassium channel 2) DrugCentral uuid:37f71dde-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.485']} DrugCentral uuid:37f7470a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) DrugCentral uuid:37f76bd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:37f794e4-7972-11ec-93d9-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:37f7bf6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96PR1 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:37f7e87c-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:37f81162-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.348']} DrugCentral uuid:37f83a66-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:37f8641e-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:37f88d4a-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:37f8b662-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:37f8e0b0-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:37f90bc6-7972-11ec-93d9-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:37f935c4-7972-11ec-93d9-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:37f95edc-7972-11ec-93d9-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:37f98858-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:37f9b17a-7972-11ec-93d9-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:37f9da6a-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.071']} DrugCentral uuid:37fa0bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:37fa0bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:37fa0bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:37fa5576-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:37fa5576-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:37fa5576-7972-11ec-93d9-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:37fa96bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:37fac204-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:37faeb44-7972-11ec-93d9-0242ac110002 UniProtKB:P22462 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:37fb1434-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULQ1 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Two pore calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:37fb3d4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NHX9 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Two pore calcium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:37fb66dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:37fb8ff4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:37fbb8f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:37fbe6a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:37fbe6a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:37fc1be0-7972-11ec-93d9-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Transitional endoplasmic reticulum ATPase) DrugCentral uuid:37fc40c0-7972-11ec-93d9-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:37fc6578-7972-11ec-93d9-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:37fc8b7a-7972-11ec-93d9-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:37fcb118-7972-11ec-93d9-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:37fcd5e4-7972-11ec-93d9-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:37fcfa88-7972-11ec-93d9-0242ac110002 UniProtKB:Q16854 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Deoxyguanosine kinase, mitochondrial) DrugCentral uuid:37fd1f9a-7972-11ec-93d9-0242ac110002 UniProtKB:P60891 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Ribose-phosphate pyrophosphokinase 1) DrugCentral uuid:37fd4592-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:37fd6eaa-7972-11ec-93d9-0242ac110002 UniProtKB:Q04400 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Adenylate cyclase type V) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:37fd97cc-7972-11ec-93d9-0242ac110002 UniProtKB:P50247 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Adenosylhomocysteinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:37fdc1b6-7972-11ec-93d9-0242ac110002 UniProtKB:P80404 biolink:molecularly_interacts_with DrugCentral:2819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vigabatrin is inhibitor of Enzyme (4-aminobutyrate aminotransferase, mitochondrial) DrugCentral uuid:37fde682-7972-11ec-93d9-0242ac110002 UniProtKB:P50554 biolink:molecularly_interacts_with DrugCentral:2819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vigabatrin targets Enzyme (Gamma-amino-N-butyrate transaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:37fe0f9a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.76']} DrugCentral uuid:37fe389e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.81']} DrugCentral uuid:37fe62ba-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:37fe8bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:37feb4fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:37fede2a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine is antagonist of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:37ff079c-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:37ff30aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:37ff556c-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:37ff7a1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:37ff9f86-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.728']} DrugCentral uuid:37ffc894-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.298']} DrugCentral uuid:37fff1a2-7972-11ec-93d9-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38003afe-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3800c604-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3800ef6c-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:380118a2-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:380141a6-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.6']} DrugCentral uuid:38016b72-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:3801902a-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:3801b4e2-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:3801d97c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:38020744-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:38020744-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:38020744-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38026892-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3802e1f0-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vindesine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.607']} DrugCentral uuid:38030af4-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3803340c-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.271']} DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38037c6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3803f734-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:38042024-7972-11ec-93d9-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:38044932-7972-11ec-93d9-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine is inhibitor of Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:38047696-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:38047696-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:3804abb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (11-cis retinol dehydrogenase) DrugCentral uuid:3804d064-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NR8 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinol dehydrogenase 12) DrugCentral uuid:3804f530-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NBN7 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinol dehydrogenase 13) DrugCentral uuid:38051a60-7972-11ec-93d9-0242ac110002 UniProtKB:P10745 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Surface antigen (Retinol-binding protein 3) DrugCentral uuid:38053f0e-7972-11ec-93d9-0242ac110002 UniProtKB:P82980 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 5) DrugCentral uuid:380563bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q96R05 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinoid-binding protein 7) DrugCentral uuid:38058888-7972-11ec-93d9-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3805b2cc-7972-11ec-93d9-0242ac110002 UniProtKB:P50120 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 2) DrugCentral uuid:3805d78e-7972-11ec-93d9-0242ac110002 UniProtKB:O94788 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinal dehydrogenase 2) DrugCentral uuid:3805fc46-7972-11ec-93d9-0242ac110002 UniProtKB:P00352 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinal dehydrogenase 1) DrugCentral uuid:380620ea-7972-11ec-93d9-0242ac110002 UniProtKB:P12271 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Transporter (Retinaldehyde-binding protein 1) DrugCentral uuid:3806473c-7972-11ec-93d9-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3806704a-7972-11ec-93d9-0242ac110002 UniProtKB:P09455 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 1) DrugCentral uuid:3806950c-7972-11ec-93d9-0242ac110002 UniProtKB:P49116 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol is agonist of Nuclear other (Nuclear receptor subfamily 2 group C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:3806bdd4-7972-11ec-93d9-0242ac110002 UniProtKB:O60779 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Transporter (Thiamine transporter 1) DrugCentral uuid:3806e3a4-7972-11ec-93d9-0242ac110002 UniProtKB:P29401 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Transketolase) DrugCentral uuid:3807082a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3S4 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Kinase (Thiamin pyrophosphokinase 1) DrugCentral uuid:38072cd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BU02 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Thiamine-triphosphatase) DrugCentral uuid:3807529e-7972-11ec-93d9-0242ac110002 UniProtKB:P51854 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Transketolase-like protein 1) DrugCentral uuid:38077774-7972-11ec-93d9-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3807a1a4-7972-11ec-93d9-0242ac110002 UniProtKB:A2RI47 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Transporter (Thiamine transporter ThiT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.91']} DrugCentral uuid:3807caa8-7972-11ec-93d9-0242ac110002 UniProtKB:P30043 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Enzyme (Flavin reductase (NADPH)) DrugCentral uuid:3807ef4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q969G6 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Kinase (Riboflavin kinase) DrugCentral uuid:380813fa-7972-11ec-93d9-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:38083d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:38086666-7972-11ec-93d9-0242ac110002 UniProtKB:P40261 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinamide N-methyltransferase) DrugCentral uuid:38088b0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15274 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinate-nucleotide pyrophosphorylase [carboxylating]) DrugCentral uuid:3808afb8-7972-11ec-93d9-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinamide phosphoribosyltransferase) DrugCentral uuid:3808d4f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q80Z39 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3808fe00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EP66 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3809270e-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:3809501c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:38097a1a-7972-11ec-93d9-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Serine hydroxymethyltransferase, cytosolic) DrugCentral uuid:38099ed2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NVS9 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Pyridoxine-5'-phosphate oxidase) DrugCentral uuid:3809c376-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD0 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Pyridoxal phosphate phosphatase) DrugCentral uuid:3809e824-7972-11ec-93d9-0242ac110002 UniProtKB:O00764 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Kinase (Pyridoxal kinase) DrugCentral uuid:380a0d22-7972-11ec-93d9-0242ac110002 UniProtKB:P35520 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Cystathionine beta-synthase) DrugCentral uuid:380a31c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y617 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Phosphoserine aminotransferase) DrugCentral uuid:380a566a-7972-11ec-93d9-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:380a7b22-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:380aa070-7972-11ec-93d9-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:380ac528-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:380aee0e-7972-11ec-93d9-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:380b12e4-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.68']} DrugCentral uuid:380b3cba-7972-11ec-93d9-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:380b6186-7972-11ec-93d9-0242ac110002 UniProtKB:Q02318 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (Sterol 26-hydroxylase, mitochondrial) DrugCentral uuid:380b8620-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydrotachysterol targets Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:380baace-7972-11ec-93d9-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:380bd652-7972-11ec-93d9-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:380bff60-7972-11ec-93d9-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:380c2882-7972-11ec-93d9-0242ac110002 UniProtKB:P35574 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:380c51b8-7972-11ec-93d9-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose is inhibitor of Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:380c7b66-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:380ca47e-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['8.73']} DrugCentral uuid:380ccda0-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:380cf69a-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:380d2322-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['5.844']} DrugCentral uuid:380d4c58-7972-11ec-93d9-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:380d75f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:380d9f6e-7972-11ec-93d9-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:380dc886-7972-11ec-93d9-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:380df1bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6A2 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cholesterol 24-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:380e1ad4-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.98']} DrugCentral uuid:380e448c-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.867']} DrugCentral uuid:380e6dae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:380e96c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16549 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Proprotein convertase subtilisin/kexin type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:380ebffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N0U8 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Vitamin K epoxide reductase complex subunit 1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.284']} DrugCentral uuid:380eeaea-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.75']} DrugCentral uuid:380f140c-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:380f3d1a-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:380f6628-7972-11ec-93d9-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:380f8f86-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:380fb876-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:380fe26a-7972-11ec-93d9-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:38100c54-7972-11ec-93d9-0242ac110002 UniProtKB:P08709 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor VII) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3810354e-7972-11ec-93d9-0242ac110002 UniProtKB:P04070 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Vitamin K-dependent protein C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:38105e3e-7972-11ec-93d9-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:38108738-7972-11ec-93d9-0242ac110002 UniProtKB:P03951 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor XI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3810b0c8-7972-11ec-93d9-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3810d9d6-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:381102e4-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.873']} DrugCentral uuid:38112bf2-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.114']} DrugCentral uuid:38115546-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.646']} DrugCentral uuid:38117e54-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:3811a76c-7972-11ec-93d9-0242ac110002 UniProtKB:P47712 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytosolic phospholipase A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:3811d066-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3811fb36-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:38122426-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.419']} DrugCentral uuid:38124d52-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.359']} DrugCentral uuid:38127656-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3812a1d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.452']} DrugCentral uuid:3812caa2-7972-11ec-93d9-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:3812f3ce-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38131db8-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.269']} DrugCentral uuid:381346b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:38136fc0-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:381398d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3813c268-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3813ec7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3814157e-7972-11ec-93d9-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:38143e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:381468e4-7972-11ec-93d9-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:2856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zalcitabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:38148dba-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zalcitabine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3814beb6-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:3814beb6-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:3814beb6-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:3815081c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:3815081c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:3815081c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:38154944-7972-11ec-93d9-0242ac110002 UniProtKB:P16207 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:38157252-7972-11ec-93d9-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:38159bec-7972-11ec-93d9-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:3815c4e6-7972-11ec-93d9-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:3815edd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q75VQ4 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:381616c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q6Q793 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:381641d2-7972-11ec-93d9-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:38166ad6-7972-11ec-93d9-0242ac110002 UniProtKB:Q2LFS1 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:381693d0-7972-11ec-93d9-0242ac110002 UniProtKB:C4LRQ6 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3816bcde-7972-11ec-93d9-0242ac110002 UniProtKB:Q20MD3 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:3816e650-7972-11ec-93d9-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:38170f36-7972-11ec-93d9-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3817381c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ49 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:381761b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3R4 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:38178cd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q07599 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:3817b5da-7972-11ec-93d9-0242ac110002 UniProtKB:Q3S340 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3817df7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WWR8 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.58']} DrugCentral uuid:38180a9e-7972-11ec-93d9-0242ac110002 UniProtKB:D5F1R0 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:381833d4-7972-11ec-93d9-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.76']} DrugCentral uuid:38185cc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XV28 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:381885b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:3818af12-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3818d834-7972-11ec-93d9-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3819014c-7972-11ec-93d9-0242ac110002 UniProtKB:P23919 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:38192a64-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3819546c-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:38197d70-7972-11ec-93d9-0242ac110002 UniProtKB:P03362 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Polyprotein (Gag-Pro-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3819a66a-7972-11ec-93d9-0242ac110002 UniProtKB:Q72549 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3819d068-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:3819f9ee-7972-11ec-93d9-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:381a2306-7972-11ec-93d9-0242ac110002 UniProtKB:Q9PPP5 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:381a4c1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:381a759a-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:381a9ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:381ac7ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:381af088-7972-11ec-93d9-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.071']} DrugCentral uuid:381b1a22-7972-11ec-93d9-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:381b4344-7972-11ec-93d9-0242ac110002 UniProtKB:P20292 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Cytosolic other (Arachidonate 5-lipoxygenase-activating protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:381b6c3e-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:381b9556-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:381bc238-7972-11ec-93d9-0242ac110002 UniProtKB:P48999 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:381bebbe-7972-11ec-93d9-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:381c149a-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.727']} DrugCentral uuid:381c3d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:381c66ca-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:381c8fa6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:381cb8b4-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:381ce294-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:381d0bb6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:381d34ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:381d5dd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:381d8866-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:381db2aa-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:381ddd02-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:381e0610-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:381e3018-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.565']} DrugCentral uuid:381e5944-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:381e8266-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:381eab88-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:381ed5d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:381efeee-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:381f282e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:381f529a-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:381f7bb2-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:381fa4ca-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:381fcef0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:381ff8da-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:382021fc-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:38204b28-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:3820744a-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:38209e98-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3820c7b0-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3820f0dc-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.114']} DrugCentral uuid:382119f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:3821408c-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:382169a4-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:382192c6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:3821bc56-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.536']} DrugCentral uuid:3821e578-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:38220eae-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:382237bc-7972-11ec-93d9-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:38226192-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:38228ab4-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:3822b3cc-7972-11ec-93d9-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3822dcda-7972-11ec-93d9-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:38230e9e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38230e9e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38230e9e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38235002-7972-11ec-93d9-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:38237924-7972-11ec-93d9-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3823a53e-7972-11ec-93d9-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3823cf78-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3823f890-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:382421b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:38244b7e-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:382474be-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:38249df4-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3824c70c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:3824f1b4-7972-11ec-93d9-0242ac110002 UniProtKB:P50281 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Matrix metalloproteinase-14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:38251b62-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:3825448e-7972-11ec-93d9-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:38256e00-7972-11ec-93d9-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3825970e-7972-11ec-93d9-0242ac110002 UniProtKB:P22939 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3825c030-7972-11ec-93d9-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:3825e952-7972-11ec-93d9-0242ac110002 UniProtKB:Q12051 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3826131e-7972-11ec-93d9-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:38263c4a-7972-11ec-93d9-0242ac110002 UniProtKB:O00481 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Unclassified (Butyrophilin subfamily 3 member A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:38266530-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:38268e52-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3826b83c-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:3826e168-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:38270a8a-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:382733a2-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.4']} DrugCentral uuid:38275d50-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:38278e24-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:38278e24-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:38278e24-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3827d0c8-7972-11ec-93d9-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3827fa94-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:382823b6-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:38284cce-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.703']} DrugCentral uuid:382876ea-7972-11ec-93d9-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3828a0f2-7972-11ec-93d9-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3828ca1e-7972-11ec-93d9-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3828f34a-7972-11ec-93d9-0242ac110002 UniProtKB:P19969 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:3829248c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:3829248c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:3829248c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:38296ee2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:38296ee2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:38296ee2-7972-11ec-93d9-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:3829b898-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:3829b898-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:3829b898-7972-11ec-93d9-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:382a019a-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:382a019a-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:382a019a-7972-11ec-93d9-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382a7f76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:382b6666-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:382b6666-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:382b6666-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:382bb01c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:382bb01c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:382bb01c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:382bf98c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:382bf98c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:382bf98c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:382c4446-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:382c4446-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:382c4446-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:382c8f96-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:382c8f96-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:382c8f96-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:382cd122-7972-11ec-93d9-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:382cfa26-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:382d233e-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.367']} DrugCentral uuid:382d5020-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:382d5020-7972-11ec-93d9-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:382d85c2-7972-11ec-93d9-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:382daa66-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:382dd374-7972-11ec-93d9-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:382df930-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.252']} DrugCentral uuid:382e2248-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:382e4b56-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:382e745a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:382e9dd6-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:382ec6da-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:382eefca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:382f18ec-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:382f42a4-7972-11ec-93d9-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:382f6ba8-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:382f94c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:382fbde2-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:382fe9de-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:383012ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:38303cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:38306684-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:38308fb0-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3830b8d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:3830e1c2-7972-11ec-93d9-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:38310b5c-7972-11ec-93d9-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:38313456-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:38315d6e-7972-11ec-93d9-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:38318668-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3831b1b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3831dad2-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:3832085e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:3832085e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:38323f68-7972-11ec-93d9-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3832688a-7972-11ec-93d9-0242ac110002 UniProtKB:Q6NSN2 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:3832918e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:3832bab0-7972-11ec-93d9-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3832e486-7972-11ec-93d9-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3833469c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:38342f1c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:38342f1c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:38342f1c-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:38347832-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:38347832-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:38347832-7972-11ec-93d9-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:3834c1fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:3834c1fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:3834c1fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:38350b12-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:38350b12-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:38350b12-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:38355572-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:38355572-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:38355572-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:3835a086-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3835a086-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3835a086-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3835ea32-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:3835ea32-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:3835ea32-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:38363348-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:38363348-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:38363348-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:38367498-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.394']} DrugCentral uuid:38369e28-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:3836c736-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3836f030-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:383719a2-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.686']} DrugCentral uuid:3837433c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:38376c36-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:38379526-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3837be98-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:3837e7a6-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:383810aa-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3838399a-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:3838633e-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:38388c42-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.273']} DrugCentral uuid:3838b55a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:3838de40-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.606']} DrugCentral uuid:3839099c-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:3839328c-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:38395b90-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.704']} DrugCentral uuid:3839846c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:3839ae4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:3839d750-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:383a002c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:383a29ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.585']} DrugCentral uuid:383a52f2-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:383a7bf6-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:383aa4dc-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.016']} DrugCentral uuid:383acf5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.441']} DrugCentral uuid:383af8ba-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:383b22f4-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.326']} DrugCentral uuid:383b4bf8-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:383b756a-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:383b9e82-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:383bc790-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:383bf09e-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:383c1a42-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:383c3ef0-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:383c67ea-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:383c8c8e-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol is antagonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:383cb2d6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:383cd798-7972-11ec-93d9-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) DrugCentral uuid:383cfc5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q02294 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:383d264e-7972-11ec-93d9-0242ac110002 UniProtKB:P54282 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:383d4fac-7972-11ec-93d9-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotarolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:383d78a6-7972-11ec-93d9-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotarolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:383da18c-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eledoisin is agonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:383dca7c-7972-11ec-93d9-0242ac110002 UniProtKB:P29371 biolink:molecularly_interacts_with DrugCentral:2955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eledoisin targets GPCR (Neuromedin-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.66']} DrugCentral uuid:383df416-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:383e1d1a-7972-11ec-93d9-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:383e4600-7972-11ec-93d9-0242ac110002 UniProtKB:P16235 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:383e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:383e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:383e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:383eb19e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:2960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifamurtide is activator of Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) DrugCentral uuid:383ed642-7972-11ec-93d9-0242ac110002 UniProtKB:Q96EB6 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacetylase sirtuin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:383eff28-7972-11ec-93d9-0242ac110002 UniProtKB:Q15077 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['4']} DrugCentral uuid:383f28a4-7972-11ec-93d9-0242ac110002 UniProtKB:P47900 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:383f51c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IXJ6 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacetylase sirtuin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:383f7aa2-7972-11ec-93d9-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:383fa3a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:383fcd2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:383ff626-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:38401f0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:38404950-7972-11ec-93d9-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:38407330-7972-11ec-93d9-0242ac110002 UniProtKB:Q5VLE3 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (RmtA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:38409c20-7972-11ec-93d9-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.749']} DrugCentral uuid:3840c542-7972-11ec-93d9-0242ac110002 UniProtKB:O15648 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (ATP-dependent 6-phosphofructokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:384115c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3841b8bc-7972-11ec-93d9-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.963']} DrugCentral uuid:3841e1d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:38420ad8-7972-11ec-93d9-0242ac110002 UniProtKB:Q80Z26 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Nucleoside triphosphate diphosphohydrolase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3842354e-7972-11ec-93d9-0242ac110002 UniProtKB:O35795 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Ectonucleoside triphosphate diphosphohydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:38425e5c-7972-11ec-93d9-0242ac110002 UniProtKB:P49654 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:38428756-7972-11ec-93d9-0242ac110002 UniProtKB:P49653 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:3842b05a-7972-11ec-93d9-0242ac110002 UniProtKB:P47824 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3842d9b8-7972-11ec-93d9-0242ac110002 UniProtKB:P51578 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:384302bc-7972-11ec-93d9-0242ac110002 UniProtKB:P42224 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 1-alpha/beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:38432bde-7972-11ec-93d9-0242ac110002 UniProtKB:P42229 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:384355a0-7972-11ec-93d9-0242ac110002 UniProtKB:P51692 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 5B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:38437eae-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triptorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.025']} DrugCentral uuid:3843a794-7972-11ec-93d9-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:2968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triptorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3843d08e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:3843f654-7972-11ec-93d9-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:3844239a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:3844239a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:3844239a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:38445d56-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histrelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:3844820e-7972-11ec-93d9-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:3844ab80-7972-11ec-93d9-0242ac110002 UniProtKB:Q4WLT4 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin is inhibitor of Enzyme (1,3-beta-glucan synthase catalytic subunit FksP) DrugCentral uuid:3844d042-7972-11ec-93d9-0242ac110002 UniProtKB:O13383 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin targets Unclassified (1,3-beta-D-glucan synthase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:3844fd38-7972-11ec-93d9-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.65']} DrugCentral uuid:3844fd38-7972-11ec-93d9-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.65']} DrugCentral uuid:384536d6-7972-11ec-93d9-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.873']} DrugCentral uuid:384536d6-7972-11ec-93d9-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.873']} DrugCentral uuid:38456ffc-7972-11ec-93d9-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.499']} DrugCentral uuid:38456ffc-7972-11ec-93d9-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.499']} DrugCentral uuid:3845a6ac-7972-11ec-93d9-0242ac110002 UniProtKB:P30988 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Calcitonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.086']} DrugCentral uuid:3845d050-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['12.7']} DrugCentral uuid:3845f94a-7972-11ec-93d9-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:38462258-7972-11ec-93d9-0242ac110002 UniProtKB:P47871 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon is agonist of GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38464b34-7972-11ec-93d9-0242ac110002 UniProtKB:P30082 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:38468f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:38468f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:38468f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:38468f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:38468f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:38468f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:38468f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:38468f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:38470e52-7972-11ec-93d9-0242ac110002 UniProtKB:F8V479 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:38473738-7972-11ec-93d9-0242ac110002 UniProtKB:O35659 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.36']} DrugCentral uuid:3847601e-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lepirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['13']} DrugCentral uuid:38478904-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3847b488-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3847dd78-7972-11ec-93d9-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:3848067c-7972-11ec-93d9-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.1']} DrugCentral uuid:38482f6c-7972-11ec-93d9-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3848681a-7972-11ec-93d9-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3848681a-7972-11ec-93d9-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3848681a-7972-11ec-93d9-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3848681a-7972-11ec-93d9-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3848681a-7972-11ec-93d9-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3848d142-7972-11ec-93d9-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3848d142-7972-11ec-93d9-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3848d142-7972-11ec-93d9-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3848d142-7972-11ec-93d9-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3848d142-7972-11ec-93d9-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:38492aca-7972-11ec-93d9-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.46']} DrugCentral uuid:384953ec-7972-11ec-93d9-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:38497dfe-7972-11ec-93d9-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:3849a72a-7972-11ec-93d9-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:3849d038-7972-11ec-93d9-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:3849fa68-7972-11ec-93d9-0242ac110002 UniProtKB:O96529 biolink:molecularly_interacts_with DrugCentral:2999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrantel targets Enzyme (Acetylcholinesterase) DrugCentral uuid:384a1f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:384a4888-7972-11ec-93d9-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:384a7290-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:384a9b80-7972-11ec-93d9-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:384ac54c-7972-11ec-93d9-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban is antagonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:384aee64-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:384b1aec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:384b1aec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:384b1aec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:384b5f5c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.934']} DrugCentral uuid:384b89dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:384bb2f4-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.888']} DrugCentral uuid:384bdc48-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.046']} DrugCentral uuid:384c0556-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:384c2e6e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.269']} DrugCentral uuid:384c577c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.532']} DrugCentral uuid:384c81d4-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.004']} DrugCentral uuid:384caac4-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:384cd3dc-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.092']} DrugCentral uuid:384cfcc2-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:384d27ba-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:384d50dc-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:384d79f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.965']} DrugCentral uuid:384da2ee-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.649']} DrugCentral uuid:384dcc4c-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.115']} DrugCentral uuid:384df546-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.681']} DrugCentral uuid:384e1e2c-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.192']} DrugCentral uuid:384e483e-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:384e71ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q969F8 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (KiSS-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:384e9ad2-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:384ec3c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:384eed84-7972-11ec-93d9-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:384f1674-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:384f3f64-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:384f685e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:384f91bc-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.299']} DrugCentral uuid:384fbbd8-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.651']} DrugCentral uuid:384fe50e-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:38500e26-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.843']} DrugCentral uuid:385037fc-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.912']} DrugCentral uuid:38506100-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.501']} DrugCentral uuid:38508a18-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.365']} DrugCentral uuid:3850b330-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:3850df22-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:38510830-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.844']} DrugCentral uuid:38513148-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.195']} DrugCentral uuid:38515ad8-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.761']} DrugCentral uuid:385183e6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3851ad08-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3851d6a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:38520046-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.212']} DrugCentral uuid:3852292c-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.647']} DrugCentral uuid:38525320-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:38527c10-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.735']} DrugCentral uuid:3852a604-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.498']} DrugCentral uuid:3852cefe-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3852f80c-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.809']} DrugCentral uuid:38532110-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.415']} DrugCentral uuid:38534a96-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:385373b8-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:38539cc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3853c5ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3853ef82-7972-11ec-93d9-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:38541872-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:3854416c-7972-11ec-93d9-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:38546b92-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:385494f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6IQ20 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol is inhibitor of Unclassified (N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:3854bdfe-7972-11ec-93d9-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:3042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxuridine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3854e716-7972-11ec-93d9-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:3042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxuridine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3855106a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.97']} DrugCentral uuid:38553978-7972-11ec-93d9-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.91']} DrugCentral uuid:38556290-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:38558b8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:3855bcea-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3855bcea-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3855bcea-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:38560740-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:38560740-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:38560740-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:38564b6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:38567482-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:38569d86-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:3856c662-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3856efc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:385718e2-7972-11ec-93d9-0242ac110002 UniProtKB:P54577 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Tyrosine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:38574204-7972-11ec-93d9-0242ac110002 UniProtKB:O35433 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:38576b12-7972-11ec-93d9-0242ac110002 UniProtKB:P03887 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Unclassified (NADH-ubiquinone oxidoreductase chain 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:38579556-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R4D5 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:3857be50-7972-11ec-93d9-0242ac110002 UniProtKB:Q704Y3 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is activator of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3857e74a-7972-11ec-93d9-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:38581148-7972-11ec-93d9-0242ac110002 UniProtKB:P16388 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:38583a6a-7972-11ec-93d9-0242ac110002 UniProtKB:P63142 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:38586382-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:38588c86-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3858b5b2-7972-11ec-93d9-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3858deac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NJH6 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Unclassified (Ace-orthologous acetylcholinesterase; Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:385907a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q7YWJ9 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3859308c-7972-11ec-93d9-0242ac110002 UniProtKB:K4JQ36 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:38595a1c-7972-11ec-93d9-0242ac110002 UniProtKB:P05181 biolink:molecularly_interacts_with DrugCentral:3067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbon tetrachloride targets Enzyme (Cytochrome P450 2E1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.959']} DrugCentral uuid:3859832a-7972-11ec-93d9-0242ac110002 UniProtKB:P31327 biolink:molecularly_interacts_with DrugCentral:3068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carglumic acid is positive allosteric modulator of Enzyme (Carbamoyl-phosphate synthase [ammonia], mitochondrial) DrugCentral uuid:3859af9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:3859af9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:3859af9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:3859f2a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q05193 biolink:molecularly_interacts_with DrugCentral:3082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrimonium targets Structural (Dynamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:385a1b82-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:3083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetylpyridinium targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:385a4472-7972-11ec-93d9-0242ac110002 UniProtKB:P42575 biolink:molecularly_interacts_with DrugCentral:3083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetylpyridinium targets Enzyme (Caspase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:385a6d58-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxylenol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.928']} DrugCentral uuid:385a96fc-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxylenol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.738']} DrugCentral uuid:385abfec-7972-11ec-93d9-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:3095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorquinaldol targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:385ae8f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:3096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cholic acid targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:385b11d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:3096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cholic acid is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:385b3b66-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:385b6596-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:385b9264-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:385b9264-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:385bcd74-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:385bcd74-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:385c06d6-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:385c06d6-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:385c3ff2-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:385c3ff2-7972-11ec-93d9-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:385c7968-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:385c7968-7972-11ec-93d9-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:385cae92-7972-11ec-93d9-0242ac110002 UniProtKB:P28570 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Transporter (Creatine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:385cd7a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:3101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchophen targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.9']} DrugCentral uuid:385d0252-7972-11ec-93d9-0242ac110002 UniProtKB:Q695T7 biolink:molecularly_interacts_with DrugCentral:3102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinromide is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:385d2be2-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:385d54d2-7972-11ec-93d9-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:385d7dc2-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:385da98c-7972-11ec-93d9-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:385dda74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:385dda74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:385dda74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:385e1b88-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:3124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cynarine targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:385e44dc-7972-11ec-93d9-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:3126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demoxytocin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:385e797a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:385e797a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:385e797a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:385e797a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:385ec72c-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:385eebd0-7972-11ec-93d9-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:385f14c0-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:385f3dba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:385f67e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:385f92ce-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 difluprednate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:385fbf38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:385fbf38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:385fbf38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:386000ce-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:38602af4-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:386054de-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:3158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxadrol targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:38607dc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:3162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disufenton targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:3860a704-7972-11ec-93d9-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:3162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disufenton targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:3860cffe-7972-11ec-93d9-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:3165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domitroban is antagonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:3860f916-7972-11ec-93d9-0242ac110002 UniProtKB:P30987 biolink:molecularly_interacts_with DrugCentral:3165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domitroban is antagonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:38612206-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:38614d4e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:38617670-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:38619f88-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3861c878-7972-11ec-93d9-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:3173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edoxudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3861f208-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:38621b02-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38624438-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38626d3c-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:386296ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3862bf9e-7972-11ec-93d9-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:3862e8a2-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:386312d2-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:38633e92-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDS5 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets GPCR (Oxoeicosanoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38636782-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear other (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:38639068-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enilconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:3863ba20-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:3863e324-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:38640c1e-7972-11ec-93d9-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:38643612-7972-11ec-93d9-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:38645f70-7972-11ec-93d9-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.91']} DrugCentral uuid:38648874-7972-11ec-93d9-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:3864b16e-7972-11ec-93d9-0242ac110002 UniProtKB:P00489 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Glycogen phosphorylase, muscle form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:3864da7c-7972-11ec-93d9-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:386506a0-7972-11ec-93d9-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:38652f86-7972-11ec-93d9-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:38655862-7972-11ec-93d9-0242ac110002 UniProtKB:P16232 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:3865821a-7972-11ec-93d9-0242ac110002 UniProtKB:P50233 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3865ab0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:3865d422-7972-11ec-93d9-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:3865fd3a-7972-11ec-93d9-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:386627e2-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:386650dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9CPU0 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:386679ea-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3866a2d0-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3866cd32-7972-11ec-93d9-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:3866f618-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:38671f26-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.748']} DrugCentral uuid:3867483e-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:386771d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol is agonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:38679ad2-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:3867c3d6-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.63']} DrugCentral uuid:3867ed20-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.064']} DrugCentral uuid:38681642-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:3868402c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:38686908-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3868934c-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.062']} DrugCentral uuid:3868bc6e-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:3868e55e-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:38690e62-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:386937fc-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:386960f6-7972-11ec-93d9-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:386989d2-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:3869b2cc-7972-11ec-93d9-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3869dc2a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:386a0542-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.181']} DrugCentral uuid:386a2e32-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:386a574a-7972-11ec-93d9-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:3194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacridine targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:386a824c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:3194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacridine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:386aab46-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:386ad454-7972-11ec-93d9-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:386afe20-7972-11ec-93d9-0242ac110002 UniProtKB:P39086 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:386b271a-7972-11ec-93d9-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:386b5032-7972-11ec-93d9-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:386b7936-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:386ba29e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13002 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:386bcb8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13003 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:386bf492-7972-11ec-93d9-0242ac110002 UniProtKB:P19491 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:386c1d8c-7972-11ec-93d9-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:386c494c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16099 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:386c725a-7972-11ec-93d9-0242ac110002 UniProtKB:P42260 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:386c9b9a-7972-11ec-93d9-0242ac110002 UniProtKB:P22756 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:386cc4b2-7972-11ec-93d9-0242ac110002 UniProtKB:P19490 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:386cee6a-7972-11ec-93d9-0242ac110002 UniProtKB:P19492 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:386d1778-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:386d4090-7972-11ec-93d9-0242ac110002 UniProtKB:Q01812 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:386d6994-7972-11ec-93d9-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:386d92fc-7972-11ec-93d9-0242ac110002 UniProtKB:P42264 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:386dc77c-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:386dc77c-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:386dc77c-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:386dc77c-7972-11ec-93d9-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:386e2618-7972-11ec-93d9-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:386e2618-7972-11ec-93d9-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:386e2618-7972-11ec-93d9-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:386e2618-7972-11ec-93d9-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:386e2618-7972-11ec-93d9-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:386e86b2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:386e86b2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:386e86b2-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:386edf5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:386edf5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:386edf5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:386edf5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:386edf5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:386edf5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:386edf5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:386f52ea-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:386f7c0c-7972-11ec-93d9-0242ac110002 UniProtKB:P25044 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Tyrosine-protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:386fa510-7972-11ec-93d9-0242ac110002 UniProtKB:Q7TSF2 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Transporter (Vesicular glutamate transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:386fce32-7972-11ec-93d9-0242ac110002 UniProtKB:Q13822 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:386ffa1a-7972-11ec-93d9-0242ac110002 UniProtKB:P08659 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Unclassified (Luciferin 4-monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3870231e-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.217']} DrugCentral uuid:38704c22-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:38707526-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.859']} DrugCentral uuid:38709e84-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:3870c792-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:3870f212-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:38711c24-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.641']} DrugCentral uuid:38714532-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.377']} DrugCentral uuid:38716e36-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:3871974e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.824']} DrugCentral uuid:3871c192-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:3871eaa0-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.328']} DrugCentral uuid:387213a4-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:38723cbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.688']} DrugCentral uuid:38726638-7972-11ec-93d9-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:38728f50-7972-11ec-93d9-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3872b85e-7972-11ec-93d9-0242ac110002 UniProtKB:P05121 biolink:molecularly_interacts_with DrugCentral:3224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendosal is inhibitor of Secreted (Plasminogen activator inhibitor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:3872e25c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoxazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:38730c32-7972-11ec-93d9-0242ac110002 UniProtKB:P04303 biolink:molecularly_interacts_with DrugCentral:3227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenticlor targets Enzyme (Uracil-DNA glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:38733518-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:3229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fumaric acid targets Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:38735e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:387387e8-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:3873b10a-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3873ddec-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:3873ddec-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:38743bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:3874de86-7972-11ec-93d9-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fumagillin targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:38750794-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:387530a2-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:3875599c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:387584ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3875ae88-7972-11ec-93d9-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3875d796-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:387601c6-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:38762ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:387653b0-7972-11ec-93d9-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:38767ca0-7972-11ec-93d9-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:3876a612-7972-11ec-93d9-0242ac110002 UniProtKB:O08590 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:3876cf34-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3876f838-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:38772132-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:38774d10-7972-11ec-93d9-0242ac110002 UniProtKB:Q15661 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate is inhibitor of Enzyme (Tryptase alpha/beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:3877768c-7972-11ec-93d9-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:38779f86-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3877c88a-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3877f206-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:38781b1e-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:38784422-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:38786dc6-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:387896e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:3878bfec-7972-11ec-93d9-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:3878e8dc-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:38791366-7972-11ec-93d9-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:38793cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:387965fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:38798eea-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:3879b866-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:3879e16a-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:387a0a64-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:387a346c-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:387a5e06-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:387a8714-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:387ab004-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:387ad99e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:387b02f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:387b2c8c-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.91']} DrugCentral uuid:387b5586-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:387b7ed0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:387ba900-7972-11ec-93d9-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:387bd218-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.89']} DrugCentral uuid:387bfb4e-7972-11ec-93d9-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:387c24fc-7972-11ec-93d9-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:387c4df6-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:387c76e6-7972-11ec-93d9-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:387c9fe0-7972-11ec-93d9-0242ac110002 UniProtKB:Q01693 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Bacterial leucyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:387ccaa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:3293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibufenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:387cf3aa-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:387d1ccc-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.969']} DrugCentral uuid:387d45bc-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:387d6f60-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:387d9832-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:387dc140-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.181']} DrugCentral uuid:387deb16-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.859']} DrugCentral uuid:387e1438-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.227']} DrugCentral uuid:387e3e22-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:387e673a-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:387e91ec-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:387ebb22-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:387ee41c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:387f0d34-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.496']} DrugCentral uuid:387f36a6-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:387f5fdc-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:387f88cc-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:387fb1e4-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:387fdb7e-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:388004a0-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:38802da4-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.79']} DrugCentral uuid:388056b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:3880807e-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3880a996-7972-11ec-93d9-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:3880d290-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3880fc02-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:38812510-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:38814e32-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:38817718-7972-11ec-93d9-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3881a206-7972-11ec-93d9-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3881cb1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3881f418-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:388225a0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:388225a0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:388225a0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:388269ca-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:3309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:388292ce-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:3882bbf0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3882e558-7972-11ec-93d9-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:38830e70-7972-11ec-93d9-0242ac110002 UniProtKB:O88703 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3883377e-7972-11ec-93d9-0242ac110002 UniProtKB:O60741 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:388360aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL51 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) DrugCentral uuid:38838648-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P1Z3 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3883af74-7972-11ec-93d9-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 khellin targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3883d85a-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.886']} DrugCentral uuid:38840230-7972-11ec-93d9-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:38842b70-7972-11ec-93d9-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:388454b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.527']} DrugCentral uuid:38847d8c-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:3884a6f4-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:3884cfda-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:3884f906-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3885220a-7972-11ec-93d9-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:38854bc2-7972-11ec-93d9-0242ac110002 UniProtKB:P05413 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Cytosolic other (Fatty acid-binding protein, heart) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:388574da-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:38859de8-7972-11ec-93d9-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3885c6e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14721 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is activator of Ion channel (Potassium voltage-gated channel subfamily B member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3885f388-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:38861db8-7972-11ec-93d9-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:388646b2-7972-11ec-93d9-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:38866fd4-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:38869950-7972-11ec-93d9-0242ac110002 UniProtKB:Q5NUL3 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is agonist of GPCR (Free fatty acid receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3886c27c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:3325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lodoxamide is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.793']} DrugCentral uuid:3886eb8a-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:3328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubeluzole targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3887152e-7972-11ec-93d9-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:3328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubeluzole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:38873e50-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestanolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:38876434-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestanolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.81']} DrugCentral uuid:38878d4c-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesterolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.6']} DrugCentral uuid:3887b79a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesterolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:3887e0a8-7972-11ec-93d9-0242ac110002 UniProtKB:O34667 biolink:molecularly_interacts_with DrugCentral:3347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methionine targets Unclassified (S-ribosylhomocysteine lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:388809c0-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.077']} DrugCentral uuid:388832ec-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.66']} DrugCentral uuid:38885c4a-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:38888562-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3888ae52-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:3888d760-7972-11ec-93d9-0242ac110002 UniProtKB:P17708 biolink:molecularly_interacts_with DrugCentral:3362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoguazone targets Enzyme (S-adenosylmethionine decarboxylase proenzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:38890104-7972-11ec-93d9-0242ac110002 UniProtKB:P36633 biolink:molecularly_interacts_with DrugCentral:3362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoguazone targets Enzyme (Amiloride-sensitive amine oxidase [copper-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:38892de6-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxestrol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:38892de6-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxestrol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:38896324-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:38898d04-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3889b63a-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3889e060-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:388a0978-7972-11ec-93d9-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:388a3a7e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388a3a7e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388a3a7e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388a8380-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:388a8380-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:388a8380-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:388ad862-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388ad862-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388ad862-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388ad862-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388ad862-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388ad862-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:388b3db6-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:3377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neridronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:388b67aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifenalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.88']} DrugCentral uuid:388b90c2-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:388bb9a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:388be270-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:388c0bc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:388c34aa-7972-11ec-93d9-0242ac110002 UniProtKB:H9TVJ1 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine targets GPCR (TyR1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:388c5ee4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01705 biolink:molecularly_interacts_with DrugCentral:3399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleandrin targets Unclassified (Neurogenic locus notch homolog protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:388c87ca-7972-11ec-93d9-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:388cb1aa-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:388cda90-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:388d0484-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:388d2e32-7972-11ec-93d9-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:388d5736-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:388d8026-7972-11ec-93d9-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:388da92a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01469 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Cytosolic other (Fatty acid-binding protein, epidermal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:388dd30a-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:388dfc40-7972-11ec-93d9-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:388e2526-7972-11ec-93d9-0242ac110002 UniProtKB:P07148 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:388e4e34-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:388e7800-7972-11ec-93d9-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:388ea10e-7972-11ec-93d9-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:388eca1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5NUL3 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid is agonist of GPCR (Free fatty acid receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:388ef316-7972-11ec-93d9-0242ac110002 UniProtKB:Q5T6X5 biolink:molecularly_interacts_with DrugCentral:3401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ornithine is agonist of GPCR (G-protein coupled receptor family C group 6 member A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:388f25c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:388f25c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:388f25c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:388f66de-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.684']} DrugCentral uuid:388f8ff6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.815']} DrugCentral uuid:388fb986-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.046']} DrugCentral uuid:388fe28a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.372']} DrugCentral uuid:38900bac-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.723']} DrugCentral uuid:389034c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:38905e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.925']} DrugCentral uuid:38908794-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.533']} DrugCentral uuid:3890b1b0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.778']} DrugCentral uuid:3890dc08-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.169']} DrugCentral uuid:38910548-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.943']} DrugCentral uuid:38912e60-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:3891576e-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.449']} DrugCentral uuid:38918108-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:3891aa2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.676']} DrugCentral uuid:3891d324-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3891fc1e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.445']} DrugCentral uuid:389225f4-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:38924be2-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.728']} DrugCentral uuid:38927504-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.333']} DrugCentral uuid:38929e1c-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:3892c8d8-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:3892f1e6-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.209']} DrugCentral uuid:38931ad6-7972-11ec-93d9-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:38934434-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.969']} DrugCentral uuid:38936d2e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:389396aa-7972-11ec-93d9-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:3412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybenzone targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3893bfae-7972-11ec-93d9-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:3413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycinchophen targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3893e966-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:3413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycinchophen targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3894127e-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:38943b96-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine is modulator of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.76']} DrugCentral uuid:38946472-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.658']} DrugCentral uuid:38948f2e-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.307']} DrugCentral uuid:3894b90e-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:3894e244-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:38950b52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:389534ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.27']} DrugCentral uuid:38956962-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:38956962-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:38956962-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:38956962-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3895bf16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3895bf16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3895bf16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:38960070-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3467 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picloxydine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:3896297e-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:3467 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picloxydine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:38965386-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:3474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adipic acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:38967cee-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:3896a5f2-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3896cf00-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:3896f87c-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:38972180-7972-11ec-93d9-0242ac110002 UniProtKB:P04015 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:38974a98-7972-11ec-93d9-0242ac110002 UniProtKB:P02550 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:3897739c-7972-11ec-93d9-0242ac110002 UniProtKB:P03118 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.98']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3897d256-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3898b162-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:3898b162-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:3898b162-7972-11ec-93d9-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:3898f6b8-7972-11ec-93d9-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3898f6b8-7972-11ec-93d9-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:38992bec-7972-11ec-93d9-0242ac110002 UniProtKB:P03120 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Human papillomavirus regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.15']} DrugCentral uuid:3899550e-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polyestradiol phosphate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:38997a66-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:38999f3c-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['9.398']} DrugCentral uuid:3899c89a-7972-11ec-93d9-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3899f1b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:389a1ebc-7972-11ec-93d9-0242ac110002 UniProtKB:Q7Z1V1 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (Sterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:389a47b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:389a70c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:389a9a54-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:389ac484-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.69']} DrugCentral uuid:389aed9c-7972-11ec-93d9-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:389b16be-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.98']} DrugCentral uuid:389b4058-7972-11ec-93d9-0242ac110002 UniProtKB:P18762 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:389b6966-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.292']} DrugCentral uuid:389b9274-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.199']} DrugCentral uuid:389bc352-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:389bc352-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:389bc352-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:389c0830-7972-11ec-93d9-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:3493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:389c3134-7972-11ec-93d9-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:3493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:389c6230-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:389c6230-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:389c6230-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:389ca3a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:3500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protoporphyrin targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:389ccc8e-7972-11ec-93d9-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:3500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protoporphyrin targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:389cf588-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.629']} DrugCentral uuid:389d1f54-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:389d4876-7972-11ec-93d9-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:389d71b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:389d9ad8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:3505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homonicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:389dc6fc-7972-11ec-93d9-0242ac110002 UniProtKB:P51575 biolink:molecularly_interacts_with DrugCentral:3506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxal phosphate targets Ion channel (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:389df00a-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:389e1922-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:389e42b2-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:389e6cc4-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:389e95e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:389ebf12-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:389ee8d4-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:389f1200-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:389f3b22-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:389f650c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:389f90e0-7972-11ec-93d9-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:389fba16-7972-11ec-93d9-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:389fe324-7972-11ec-93d9-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:38a00c46-7972-11ec-93d9-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:38a035d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:38a05ef8-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:38a08806-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:38a0b1dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:38a0db12-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:38a10420-7972-11ec-93d9-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:38a12d24-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:38a157a4-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:38a18120-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:38a1ab78-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:38a1d490-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:38a1fe16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:38a22710-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:38a250a0-7972-11ec-93d9-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:38a2825a-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:38a2825a-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:38a2825a-7972-11ec-93d9-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:38a2c44a-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:38a2ed58-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:38a31652-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:38a342bc-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:38a36c38-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:38a3953c-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:38a3be90-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:38a3e78a-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:38a41084-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:38a439a6-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:38a46336-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:38a48cee-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:38a4b5f2-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:38a4df0a-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:38a50a34-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:38a5339c-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:38a55cbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:38a585f4-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:38a5af7a-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:38a5d888-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:38a6018c-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:38a62aa4-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:38a6545c-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:38a67e5a-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:38a6a768-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:38a6d184-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:38a6fcb8-7972-11ec-93d9-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:38a725a8-7972-11ec-93d9-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:38a74ea2-7972-11ec-93d9-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:38a7781e-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:38a7a258-7972-11ec-93d9-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:38a7cb52-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:38a7f488-7972-11ec-93d9-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:38a81e4a-7972-11ec-93d9-0242ac110002 UniProtKB:P04745 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alpha-amylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:38a8474e-7972-11ec-93d9-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:38a87052-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:38a8994c-7972-11ec-93d9-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:38a8c32c-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:38a8ec30-7972-11ec-93d9-0242ac110002 UniProtKB:P08254 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Stromelysin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:38a91534-7972-11ec-93d9-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:38a93e92-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:38a967a0-7972-11ec-93d9-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:38a990a4-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:38a9b99e-7972-11ec-93d9-0242ac110002 UniProtKB:P48147 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prolyl endopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:38a9e324-7972-11ec-93d9-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:38aa0c28-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:38aa352c-7972-11ec-93d9-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:38aa5e26-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:38aa88f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:38aab286-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:38aadb9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:38ab04a2-7972-11ec-93d9-0242ac110002 UniProtKB:P04054 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Phospholipase A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38ab2e0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:38ab5740-7972-11ec-93d9-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:38ab8044-7972-11ec-93d9-0242ac110002 UniProtKB:P39900 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Macrophage metalloelastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:38aba952-7972-11ec-93d9-0242ac110002 UniProtKB:P45452 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Collagenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:38abd30a-7972-11ec-93d9-0242ac110002 UniProtKB:P17538 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Chymotrypsinogen B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:38abfc18-7972-11ec-93d9-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:38ac2526-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38ac4f56-7972-11ec-93d9-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:38ac7ba2-7972-11ec-93d9-0242ac110002 UniProtKB:P80276 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:38aca76c-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:38acd084-7972-11ec-93d9-0242ac110002 UniProtKB:P06737 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Glycogen phosphorylase, liver form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:38acf9e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q15046 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:38ad22be-7972-11ec-93d9-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:38ad4bae-7972-11ec-93d9-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:38ad74bc-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:38ad9e7e-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:38adc8c2-7972-11ec-93d9-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:38adf1ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:38ae1af2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:38ae4716-7972-11ec-93d9-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:38ae7010-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:38ae9928-7972-11ec-93d9-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:38aec3a8-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:38aeece8-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:38af15f6-7972-11ec-93d9-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:38af3f0e-7972-11ec-93d9-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:38af68d0-7972-11ec-93d9-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:38af91de-7972-11ec-93d9-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:38afbaec-7972-11ec-93d9-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:38afe3f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q965D5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Enoyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:38b00dd0-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:38b036de-7972-11ec-93d9-0242ac110002 UniProtKB:Q91WR5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldo-keto reductase family 1 member C21) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:38b05fec-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:38b088fa-7972-11ec-93d9-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:38b0b26c-7972-11ec-93d9-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:38b0db7a-7972-11ec-93d9-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:38b10528-7972-11ec-93d9-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:38b12eea-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:38b15898-7972-11ec-93d9-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:38b181a6-7972-11ec-93d9-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:38b1aaaa-7972-11ec-93d9-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:38b1d502-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:38b1fe10-7972-11ec-93d9-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38b2271e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:38b2502c-7972-11ec-93d9-0242ac110002 UniProtKB:P10584 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Malate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:38b27980-7972-11ec-93d9-0242ac110002 UniProtKB:P21588 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (5'-nucleotidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:38b2a298-7972-11ec-93d9-0242ac110002 UniProtKB:Q965D6 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (3-oxoacyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:38b2cc96-7972-11ec-93d9-0242ac110002 UniProtKB:Q965D7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-hydroxyacyl-ACP dehydratase; Fatty acid synthesis protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:38b2f59a-7972-11ec-93d9-0242ac110002 UniProtKB:P27986 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Phosphatidylinositol 3-kinase regulatory subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:38b31f7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPH5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (NADPH oxidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:38b34874-7972-11ec-93d9-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:38b3718c-7972-11ec-93d9-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:38b39a90-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:38b3c5f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q1CTD3 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (D-alanine--D-alanine ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:38b3f030-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC98 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase Nek6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:38b4195c-7972-11ec-93d9-0242ac110002 UniProtKB:O96394 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arginase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:38b44684-7972-11ec-93d9-0242ac110002 UniProtKB:P14635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:38b44684-7972-11ec-93d9-0242ac110002 UniProtKB:P14635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:38b47f78-7972-11ec-93d9-0242ac110002 UniProtKB:Q15078 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 5/CDK5 activator 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:38b47f78-7972-11ec-93d9-0242ac110002 UniProtKB:Q15078 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 5/CDK5 activator 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:38b4c00a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:38b4c00a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:38b4c00a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:38b4c00a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:38b511d6-7972-11ec-93d9-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:38b511d6-7972-11ec-93d9-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:38b54ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:38b54ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:38b580bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:38b5a9b6-7972-11ec-93d9-0242ac110002 UniProtKB:P29477 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:38b5d2ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q00796 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Sorbitol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:38b5fbb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99895 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Chymotrypsin C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:38b62620-7972-11ec-93d9-0242ac110002 UniProtKB:Q03114 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cell division protein kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:38b64f1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:38b6781e-7972-11ec-93d9-0242ac110002 UniProtKB:P07862 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (D-alanylalanine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:38b6a140-7972-11ec-93d9-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:38b6cada-7972-11ec-93d9-0242ac110002 UniProtKB:Q01062 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Phosphodiesterase 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:38b6f3e8-7972-11ec-93d9-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:38b71d14-7972-11ec-93d9-0242ac110002 UniProtKB:P41921 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Glutathione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:38b7479e-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:38b773a4-7972-11ec-93d9-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:38b79cc6-7972-11ec-93d9-0242ac110002 UniProtKB:P11168 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:38b7c5e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q14576 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (ELAV-like protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:38b7ef46-7972-11ec-93d9-0242ac110002 UniProtKB:Q15717 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (ELAV-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:38b81854-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:38b84176-7972-11ec-93d9-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:38b86a8e-7972-11ec-93d9-0242ac110002 UniProtKB:P19357 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:38b8946e-7972-11ec-93d9-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38b8bd90-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFU5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Inositol polyphosphate multikinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:38b8e694-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHH9 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Inositol hexakisphosphate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:38b90fac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:38b949ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:38b949ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:38b949ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:38b949ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:38b949ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:38b99a12-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:38b9c384-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:38b9eda0-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:38ba1686-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:38ba3fa8-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:38ba6956-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:38ba926e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:38babb9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.16']} DrugCentral uuid:38bae4bc-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:38bb0fdc-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:38bb38e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:38bb61e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:38bb8af2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:38bbb46e-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:38bbdd86-7972-11ec-93d9-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:38bc0a7c-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revaprazan is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:38bc0a7c-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revaprazan is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:38bc3a88-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:3529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rioprostil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) DrugCentral uuid:38bc5fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:38bc88da-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.46']} DrugCentral uuid:38bcb1d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.57']} DrugCentral uuid:38bce9ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:38bce9ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:38bce9ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:38bce9ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:38bd36fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WQX9 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (Phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:38bd6020-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:38bd8974-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:38bdb386-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:38bddc94-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:38be0660-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:38be2f82-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:38be5886-7972-11ec-93d9-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:38be8194-7972-11ec-93d9-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:38beac8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:38bed5b8-7972-11ec-93d9-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:38befec6-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:38bf27e8-7972-11ec-93d9-0242ac110002 UniProtKB:P05771 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C beta type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:38bf5150-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:38bf7a68-7972-11ec-93d9-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:38bfa380-7972-11ec-93d9-0242ac110002 UniProtKB:P22694 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:38bfcc8e-7972-11ec-93d9-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:38bff6fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:38c02012-7972-11ec-93d9-0242ac110002 UniProtKB:P05129 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C gamma type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:38c0493e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:38c0736e-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:38c09c90-7972-11ec-93d9-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:38c0c5c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:38c0eee8-7972-11ec-93d9-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:38c1185a-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:38c14172-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:38c16a80-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:38c1947e-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:38c1be36-7972-11ec-93d9-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38c1e744-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:38c21066-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:38c23974-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:38c26480-7972-11ec-93d9-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:38c28dac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:38c2b75a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:38c2e0d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:38c309f8-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:38c33306-7972-11ec-93d9-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:38c35c14-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:38c385c2-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38c3aed0-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:38c3d7f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:38c40114-7972-11ec-93d9-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:38c42c20-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:38c45556-7972-11ec-93d9-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:38c47e6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:38c4a8bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:38c4d21a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38c4fb3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:38c5245e-7972-11ec-93d9-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:38c54d76-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JI10 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:38c5772e-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:38c5a154-7972-11ec-93d9-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:38c5ca62-7972-11ec-93d9-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:38c5f460-7972-11ec-93d9-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:38c61d82-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:38c64686-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:38c66fa8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38c69924-7972-11ec-93d9-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:38c6c232-7972-11ec-93d9-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:38c6eb4a-7972-11ec-93d9-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:38c71462-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:38c73e06-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:38c76728-7972-11ec-93d9-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:38c79036-7972-11ec-93d9-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:38c7b94e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:38c7e536-7972-11ec-93d9-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:38c80e4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:38c83748-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:38c860e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:38c88a0e-7972-11ec-93d9-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38c8b33a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:38c8dc48-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:38c90600-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y243 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (RAC-gamma serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:38c92f04-7972-11ec-93d9-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:38c958a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:38c981a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:38c9aca4-7972-11ec-93d9-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:38c9d5bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:38c9fef2-7972-11ec-93d9-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:38ca2800-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:38ca5186-7972-11ec-93d9-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:38ca7a94-7972-11ec-93d9-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:38caa4d8-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:38cace72-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:38caf7a8-7972-11ec-93d9-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:38cb20ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:38cb49d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:38cb7426-7972-11ec-93d9-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:38cb9d66-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:38cbc688-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:38cbefaa-7972-11ec-93d9-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:38cc191c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:38cc4234-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:38cc6b42-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:38cc945a-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:38ccbe08-7972-11ec-93d9-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:38cce72a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:38cd104c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:38cd3950-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:38cd6614-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:38cd906c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:38cdb98e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:38cde300-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:38ce0c22-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:38ce354e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:38ce5e66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:38ce8896-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:38ceb1c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:38cedaee-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:38cf041a-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:38cf2ff8-7972-11ec-93d9-0242ac110002 UniProtKB:O76039 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase-like 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:38cf5c76-7972-11ec-93d9-0242ac110002 UniProtKB:P41743 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C iota type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:38cf8624-7972-11ec-93d9-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:38cfb040-7972-11ec-93d9-0242ac110002 UniProtKB:O60331 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:38cfd958-7972-11ec-93d9-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:38d002e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:38d02bec-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38d055ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:38d0997e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38d0997e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38d0997e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38d0997e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38d0997e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38d0997e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38d0997e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38d0997e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:38d129ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:38d129ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:38d129ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:38d129ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:38d176dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d1c29a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:38d246ca-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:38d26fd8-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:38d298e6-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.454']} DrugCentral uuid:38d2c2d0-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:38d2ebd4-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:38d314c4-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:38d33dd2-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:38d36726-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:38d39002-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:38d3b910-7972-11ec-93d9-0242ac110002 UniProtKB:P02769 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:38d3e20a-7972-11ec-93d9-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:38d40bc2-7972-11ec-93d9-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:38d435d4-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:38d45ec4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZQ4 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Neuromedin-U receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:38d48796-7972-11ec-93d9-0242ac110002 UniProtKB:P03469 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:38d4b4c8-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:38d4dde0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:38d50702-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:38d5307e-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:38d5598c-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:38d58290-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:38d5bada-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:38d5bada-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:38d5bada-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:38d5bada-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:38d5bada-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:38d614c6-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:38d63df2-7972-11ec-93d9-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:38d667b4-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:38d692de-7972-11ec-93d9-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin is antagonist of GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:38d6bfac-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:38d6bfac-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:38d6f576-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:38d71f1a-7972-11ec-93d9-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:38d74828-7972-11ec-93d9-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:38d77136-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:38d79a4e-7972-11ec-93d9-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Cytosolic other (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:38d7c8e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:38d7c8e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:38d7fe26-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:3557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbentine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:38d82720-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:3557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbentine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:38d8510a-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:38d87de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:38d87de2-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:38d8b2ee-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxedrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:38d8dc60-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZQ4 biolink:molecularly_interacts_with DrugCentral:3577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxedrine targets GPCR (Neuromedin-U receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:38d90550-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:38d929fe-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:38d952f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:38d97c88-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:38d9a56e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:38d9ce90-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:38d9f776-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:38da2340-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:38da4c62-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:38da7570-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:38da9e9c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:38dac85e-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:38daf16c-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) DrugCentral uuid:38db1642-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:38db3f28-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:38db68d6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.09']} DrugCentral uuid:38db91ee-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:38dbbc14-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:38dbe5d6-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:38dc0f0c-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:38dc3fd6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:38dc3fd6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:38dc3fd6-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:38dc8950-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:38dc8950-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:38dc8950-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:38dcdd9c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38dcdd9c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38dcdd9c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38dcdd9c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38dcdd9c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38dcdd9c-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:38dd57d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:38dd57d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:38dd57d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:38dd57d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:38dd57d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:38dd57d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:38ddb122-7972-11ec-93d9-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:38dddb16-7972-11ec-93d9-0242ac110002 UniProtKB:O75936 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Gamma-butyrobetaine dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:38de042e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99685 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:38de2d1e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:38de567c-7972-11ec-93d9-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:38de7f94-7972-11ec-93d9-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:38deaa96-7972-11ec-93d9-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:38ded3b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:38defd8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38df26a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:38df4f96-7972-11ec-93d9-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.39']} DrugCentral uuid:38df789a-7972-11ec-93d9-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.72']} DrugCentral uuid:38dfa324-7972-11ec-93d9-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:38dfcc1e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:38dff518-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:38e01e12-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:38e04766-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:38e06c14-7972-11ec-93d9-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:38e09522-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:38e0be26-7972-11ec-93d9-0242ac110002 UniProtKB:Q80W54 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (CAAX prenyl protease 1 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:38e0e7b6-7972-11ec-93d9-0242ac110002 UniProtKB:P14091 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Cathepsin E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:38e110b0-7972-11ec-93d9-0242ac110002 UniProtKB:P0DJD9 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Pepsin A-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38e139c8-7972-11ec-93d9-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:38e16362-7972-11ec-93d9-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.39']} DrugCentral uuid:38e18ce8-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:38e1b600-7972-11ec-93d9-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.82']} DrugCentral uuid:38e1df04-7972-11ec-93d9-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:38e20862-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:38e23206-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:38e25b3c-7972-11ec-93d9-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:3613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Vitamin E targets Enzyme (Glutathione S-transferase P) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:38e28436-7972-11ec-93d9-0242ac110002 UniProtKB:P49638 biolink:molecularly_interacts_with DrugCentral:3613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Vitamin E targets Transporter (Alpha-tocopherol transfer protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:38e2aec0-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:38e2d7d8-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:38e300f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.36']} DrugCentral uuid:38e32a12-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.75']} DrugCentral uuid:38e354ba-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.894']} DrugCentral uuid:38e37dd2-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:38e3a6ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:38e3cfd0-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:38e3f94c-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:38e42250-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:38e4531a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:38e4531a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:38e4531a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:38e49dfc-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38e49dfc-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38e49dfc-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:38e4df4c-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:38e5085a-7972-11ec-93d9-0242ac110002 UniProtKB:P95276 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase; Epoxide hydrolase EphB) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:38e533c0-7972-11ec-93d9-0242ac110002 UniProtKB:P07099 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:38e55cc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D379 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:38e585dc-7972-11ec-93d9-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:38e5af6c-7972-11ec-93d9-0242ac110002 UniProtKB:P16152 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Carbonyl reductase [NADPH] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:38e5d898-7972-11ec-93d9-0242ac110002 UniProtKB:Q6GI75 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:38e601b0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:38e62ae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q965D5 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.28']} DrugCentral uuid:38e65598-7972-11ec-93d9-0242ac110002 UniProtKB:P54616 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:38e67ec4-7972-11ec-93d9-0242ac110002 UniProtKB:Q6UCJ9 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-acyl carrier reductase; Enoyl-acyl carrier reductase ENR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:38e6a7e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BJJ9 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-ACP reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:38e6d0e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9RMI3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADPH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:38e6fb38-7972-11ec-93d9-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:38e72446-7972-11ec-93d9-0242ac110002 UniProtKB:M9TGV3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NULLDH]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:38e74d86-7972-11ec-93d9-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:38e77680-7972-11ec-93d9-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:38e79ffc-7972-11ec-93d9-0242ac110002 UniProtKB:Q15077 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:38e7c900-7972-11ec-93d9-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:38e7f290-7972-11ec-93d9-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:38e81c3e-7972-11ec-93d9-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:38e8457e-7972-11ec-93d9-0242ac110002 UniProtKB:O35811 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:38e86e82-7972-11ec-93d9-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:38e89786-7972-11ec-93d9-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:38e8c22e-7972-11ec-93d9-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:38e8ebd2-7972-11ec-93d9-0242ac110002 UniProtKB:P97321 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:38e914ea-7972-11ec-93d9-0242ac110002 UniProtKB:E1BI31 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Unclassified (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:38e93e16-7972-11ec-93d9-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:38e967ce-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:38e99122-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:38e9ba44-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:38e9e366-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38ea0d32-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ea5562-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:38ead24e-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.86']} DrugCentral uuid:38eafb34-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:38eb2460-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:38eb4df0-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:38eb7712-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:38eba020-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:38ebca00-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:38ebf318-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:38ec1c26-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:38ec453e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:38ec6ff0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:38ec9a0c-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:38ecc324-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:38ecec28-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:38ed15ae-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:38ed3ebc-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:38ed67fc-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:38ed911e-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:38edbaea-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:38ede4fc-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:38ee0e00-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:38ee3812-7972-11ec-93d9-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:38ee7124-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:38ee7124-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:38ee7124-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:38ee7124-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:38ee7124-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:38eeca52-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:38eef3e2-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:38ef1e4e-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:38ef478e-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:38ef7146-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:38efa22e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:38efa22e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:38efa22e-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:38efeb26-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:38efeb26-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:38efeb26-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:38f04080-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:38f04080-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:38f04080-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:38f04080-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:38f04080-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:38f04080-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:38f0a70a-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:38f0d02c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.163']} DrugCentral uuid:38f0f962-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:38f12284-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:38f14c46-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:38f17572-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.106']} DrugCentral uuid:38f19e94-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:38f1c7d4-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:38f1f2fe-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:38f21c7a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:38f245a6-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:38f26ec8-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:38f29876-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:38f2c198-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.692']} DrugCentral uuid:38f2eaa6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:38f313aa-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:38f33d94-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:38f366c0-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:38f38fd8-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:38f3ba58-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:38f3e5dc-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:38f40eea-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.182']} DrugCentral uuid:38f43802-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:38f46296-7972-11ec-93d9-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:38f48bd6-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:38f4b610-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:38f4df0a-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:38f508ae-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:38f53202-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:38f55bb0-7972-11ec-93d9-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:38f584e6-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:38f5b0ec-7972-11ec-93d9-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:38f5da18-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:38f6033a-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:38f63486-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:38f63486-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:38f63486-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:38f68544-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38f68544-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38f68544-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38f68544-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38f68544-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:38f6e6ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:38f6e6ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:38f6e6ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:38f72fda-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:38f72fda-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:38f72fda-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:38f7722e-7972-11ec-93d9-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:38f79b3c-7972-11ec-93d9-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:38f7c558-7972-11ec-93d9-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:38f7ee84-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:38f817f6-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:38f848d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:38f848d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:38f848d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:38f889de-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:38f8b3d2-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:38f8dd1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:38f90648-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:38f93140-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bropirimine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:38f95a8a-7972-11ec-93d9-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:3707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorthenoxazine targets Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:38f983c0-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciramadol is modulator of GPCR (Mu-type opioid receptor) DrugCentral uuid:38f9a896-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:3715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobenztropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:38f9d9e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:38f9d9e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:38f9d9e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:38fa22da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:38fa22da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:38fa22da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:38fa6420-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 myrtecaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.316']} DrugCentral uuid:38fa95c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:38fa95c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:38fa95c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:38fadbda-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:38fadbda-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:38fb1294-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:38fb3ed6-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:38fb67e4-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:38fb90f2-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:38fbba6e-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:38fbe37c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:38fc0c9e-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:38fc35b6-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:38fc5f82-7972-11ec-93d9-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:38fc88a4-7972-11ec-93d9-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:38fcb1bc-7972-11ec-93d9-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:38fcdb88-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:38fd059a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:38fd2ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:38fd581a-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:38fd81aa-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:38fdaac2-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:38fdd3da-7972-11ec-93d9-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:38fdfcfc-7972-11ec-93d9-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:38fe268c-7972-11ec-93d9-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:38fe4fae-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:38fe79f2-7972-11ec-93d9-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:38fea3dc-7972-11ec-93d9-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:38fecef2-7972-11ec-93d9-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:38fef800-7972-11ec-93d9-0242ac110002 UniProtKB:P11416 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:38ff2122-7972-11ec-93d9-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:38ff4a3a-7972-11ec-93d9-0242ac110002 UniProtKB:P22605 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:38ff73b6-7972-11ec-93d9-0242ac110002 UniProtKB:P18911 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:38ff9cd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q05343 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:38ffc5c8-7972-11ec-93d9-0242ac110002 UniProtKB:P22736 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Nuclear receptor subfamily 4 group A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:38ffef94-7972-11ec-93d9-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:390018a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13133 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Oxysterols receptor LXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:390041a6-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:3871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 artemisinin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:39006b4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:3900966a-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:3900bfa0-7972-11ec-93d9-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:3900e8b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:390111bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:39013b42-7972-11ec-93d9-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.843']} DrugCentral uuid:3901681a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3901681a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3901a8ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3901a8ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3901a8ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3901a8ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3901f69a-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:39021fbc-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:390249d8-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:39027412-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:39029d48-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasone butyrate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3902c214-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:3902eb40-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:390314d0-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.665']} DrugCentral uuid:39033df2-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.372']} DrugCentral uuid:39036728-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:39039054-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:3903ba20-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:3903e338-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:39040c3c-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:390437de-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:390462ae-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:39048bc6-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:3904b4fc-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:3904de96-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:390507cc-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.25']} DrugCentral uuid:39054034-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:39054034-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:39054034-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:39054034-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:39054034-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3905a1e6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:3905a1e6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:3905a1e6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:3905ebb0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:3905ebb0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:3905ebb0-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:3906316a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:39065a96-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:390683b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:3906adac-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3906d6d8-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3906ffe6-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.79']} DrugCentral uuid:39072926-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:390752f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:39077c0a-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3907a518-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:3907ce26-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3907fa54-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:39082574-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:39084e82-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:39087826-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3908a152-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:3908ca6a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.57']} DrugCentral uuid:3908f38c-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:39091d3a-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3909477e-7972-11ec-93d9-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:39097082-7972-11ec-93d9-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:39099a6c-7972-11ec-93d9-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3909c618-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3909f20a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolasetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.226']} DrugCentral uuid:390a1b22-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolasetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.698']} DrugCentral uuid:390a444e-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:3944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide phosphate is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:390a699c-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:390a92d2-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.928']} DrugCentral uuid:390abbfe-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:390ae5e8-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.208']} DrugCentral uuid:390b0f1e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.971']} DrugCentral uuid:390b3868-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:390b61a8-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.793']} DrugCentral uuid:390b8c46-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.801']} DrugCentral uuid:390bb5cc-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.748']} DrugCentral uuid:390bdf02-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:390c0806-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:390c3222-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:390c5b30-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.122']} DrugCentral uuid:390c8452-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:390cad56-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:390cdee8-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:390cdee8-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:390cdee8-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:390d204c-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone butyrate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:390d4900-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ilaprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:390d4900-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ilaprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:390d7aec-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:390da418-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:390dcd30-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:390df71a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.407']} DrugCentral uuid:390e203c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.125']} DrugCentral uuid:390e4968-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.924']} DrugCentral uuid:390e7294-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.891']} DrugCentral uuid:390e9c4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.586']} DrugCentral uuid:390ec56e-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.244']} DrugCentral uuid:390eee90-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.451']} DrugCentral uuid:390f18e8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.539']} DrugCentral uuid:390f4494-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is allosteric modulator of Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:390f6e2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:390fa2b8-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:390fa2b8-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:390fa2b8-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:390fa2b8-7972-11ec-93d9-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:390ff088-7972-11ec-93d9-0242ac110002 UniProtKB:P91730 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is modulator of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:39101568-7972-11ec-93d9-0242ac110002 UniProtKB:Q25634 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is modulator of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:39103a34-7972-11ec-93d9-0242ac110002 UniProtKB:P11507 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sarcoplasmic/endoplasmic reticulum calcium ATPase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:391063e2-7972-11ec-93d9-0242ac110002 UniProtKB:P06685 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:39108d0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q64578 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sarcoplasmic/endoplasmic reticulum calcium ATPase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:3910b626-7972-11ec-93d9-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is allosteric modulator of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3910df2a-7972-11ec-93d9-0242ac110002 UniProtKB:P29029 biolink:molecularly_interacts_with DrugCentral:3976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kinetin targets Enzyme (Endochitinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3911098c-7972-11ec-93d9-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:391136d2-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.65']} DrugCentral uuid:39116062-7972-11ec-93d9-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3911897a-7972-11ec-93d9-0242ac110002 UniProtKB:P00371 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:3911b30a-7972-11ec-93d9-0242ac110002 UniProtKB:P11344 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:3911dc22-7972-11ec-93d9-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:39120508-7972-11ec-93d9-0242ac110002 UniProtKB:B2ZB02 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:39122f2e-7972-11ec-93d9-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:39125972-7972-11ec-93d9-0242ac110002 UniProtKB:Q00024 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polyphenol oxidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3912829e-7972-11ec-93d9-0242ac110002 UniProtKB:O75936 biolink:molecularly_interacts_with DrugCentral:3995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meldonium targets Enzyme (Gamma-butyrobetaine dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3912abca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:3998 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octanoic acid targets GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:3912d5fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:3998 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octanoic acid targets GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:3912ff94-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niperotidine is antagonist of GPCR (Histamine H2 receptor) DrugCentral uuid:39132488-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:39134d96-7972-11ec-93d9-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan is antagonist of GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3913773a-7972-11ec-93d9-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3913a03e-7972-11ec-93d9-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3913c96a-7972-11ec-93d9-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3913f64c-7972-11ec-93d9-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3913f64c-7972-11ec-93d9-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:39142c7a-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:3914557e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:39147eaa-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3914a9ac-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3914d30a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:3914fc0e-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:39152544-7972-11ec-93d9-0242ac110002 UniProtKB:Q14832 biolink:molecularly_interacts_with DrugCentral:4050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spaglumic acid is agonist of GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:39154fba-7972-11ec-93d9-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:391578d2-7972-11ec-93d9-0242ac110002 UniProtKB:P48147 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Prolyl endopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3915a1e0-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:391604c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:3916ec62-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:3917157a-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:39173f0a-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3917682c-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.81']} DrugCentral uuid:3917916c-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3917bb1a-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3917e540-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.78']} DrugCentral uuid:39180e62-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.44']} DrugCentral uuid:3918377a-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.807']} DrugCentral uuid:391861fa-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.243']} DrugCentral uuid:39188ba8-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.929']} DrugCentral uuid:3918b4c0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.425']} DrugCentral uuid:3918ddd8-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.857']} DrugCentral uuid:39190736-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:3919306c-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:39195ab0-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.802']} DrugCentral uuid:391983c8-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.952']} DrugCentral uuid:3919ad8a-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.789']} DrugCentral uuid:3919d68e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3919ffa6-7972-11ec-93d9-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:391a297c-7972-11ec-93d9-0242ac110002 UniProtKB:P13674 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Prolyl 4-hydroxylase subunit alpha-1) DrugCentral uuid:391a4f7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02809 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1) DrugCentral uuid:391a742c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGH3 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Transporter (Solute carrier family 23 member 2) DrugCentral uuid:391a98c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHI7 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Transporter (Solute carrier family 23 member 1) DrugCentral uuid:391abd74-7972-11ec-93d9-0242ac110002 UniProtKB:P00689 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Pancreatic alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:391ae722-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:391b1026-7972-11ec-93d9-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:391b392a-7972-11ec-93d9-0242ac110002 UniProtKB:P22939 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:391b62d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12051 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:391b8fec-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamlodipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:391b8fec-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamlodipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:391bbf44-7972-11ec-93d9-0242ac110002 UniProtKB:P0DJD9 biolink:molecularly_interacts_with DrugCentral:4106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sucralfate is inhibitor of Enzyme (Pepsin A-5) DrugCentral uuid:391be41a-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is agonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:391c0eea-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.99']} DrugCentral uuid:391c37da-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:391c60d4-7972-11ec-93d9-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is allosteric modulator of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:391c89ce-7972-11ec-93d9-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:391cb34a-7972-11ec-93d9-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is allosteric modulator of Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:391cdc58-7972-11ec-93d9-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:391d055c-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:391d2e60-7972-11ec-93d9-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:391d5818-7972-11ec-93d9-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:391d8130-7972-11ec-93d9-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:391daa52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:391dd892-7972-11ec-93d9-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:391dd892-7972-11ec-93d9-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:391e14ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QZN9 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:391e14ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QZN9 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:391e4a0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:391e7388-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:391e9cb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:391ec5d6-7972-11ec-93d9-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:391eef8e-7972-11ec-93d9-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:391f1e78-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:391f1e78-7972-11ec-93d9-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:391f51cc-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:391f51cc-7972-11ec-93d9-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:391f811a-7972-11ec-93d9-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.229']} DrugCentral uuid:391fab68-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:391fd5f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:391fff00-7972-11ec-93d9-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3920282c-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:392051b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.229']} DrugCentral uuid:39207ab6-7972-11ec-93d9-0242ac110002 UniProtKB:O60741 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) DrugCentral uuid:39209f8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL51 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) DrugCentral uuid:3920c44e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P1Z3 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3) DrugCentral uuid:3920e9b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) DrugCentral uuid:39210e68-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:4113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasugrel is antagonist of GPCR (P2Y purinoceptor 12) DrugCentral uuid:39213320-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:392157ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:39217dbc-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3921a74c-7972-11ec-93d9-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3921d05a-7972-11ec-93d9-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:3921f986-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:392222ee-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:39224c06-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3922753c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.75']} DrugCentral uuid:39229e54-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.187']} DrugCentral uuid:3922c816-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:3922f12e-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.61']} DrugCentral uuid:39231a46-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:39234354-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.93']} DrugCentral uuid:39236e88-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:392397a0-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.47']} DrugCentral uuid:3923c0c2-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:3923eb10-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.73']} DrugCentral uuid:3924141e-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:39243d0e-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.644']} DrugCentral uuid:39246626-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:39248fc0-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:3924b9f0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.107']} DrugCentral uuid:3924e2e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.039']} DrugCentral uuid:39250bee-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.491']} DrugCentral uuid:392536dc-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.565']} DrugCentral uuid:39256026-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:3925893e-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:3925b260-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:3925dbd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.504']} DrugCentral uuid:392604cc-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:39262dd0-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:39265774-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:39268140-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3926aa58-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3926d384-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:3926fdf0-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:392727bc-7972-11ec-93d9-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:392750de-7972-11ec-93d9-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:392779ec-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3927a368-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3927cc6c-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3927f660-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:39281f96-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3928494e-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3928727a-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39289b92-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3928c4a0-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3928ee8a-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3929178e-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:39294092-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:39296a22-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:39299358-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3929bc84-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3929e5b0-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:392a0f7c-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.1']} DrugCentral uuid:392a38a8-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.31']} DrugCentral uuid:392a61ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:392a8ace-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:392ab4f4-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:392adf42-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:392b086e-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:392b3186-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:392b5af8-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:392b8410-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:392bad1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:392bd62c-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:392c00de-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:392c29f6-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:392c53a4-7972-11ec-93d9-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:392c7e10-7972-11ec-93d9-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:392caa70-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:392cd400-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:392cfcfa-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:392d2676-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:392d4f8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:392d7888-7972-11ec-93d9-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:392da1a0-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:392dcb62-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:392df45c-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:392e1d6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:392e4664-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:392e7094-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:392e9998-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:392ec2b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:392eec18-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:392f1530-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:392f3e52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:392f676a-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:392f90f0-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:392fba26-7972-11ec-93d9-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:392fe32a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:39300d3c-7972-11ec-93d9-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:393037a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:393060c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:393089e2-7972-11ec-93d9-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3930b322-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Tyrosine-protein kinase ITK/TSK) DrugCentral uuid:3930d852-7972-11ec-93d9-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:393102a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:39312bcc-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:393154f8-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:39317ea6-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3931a7c8-7972-11ec-93d9-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3931d0c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3931fb06-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:39322428-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:39324d4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:39327658-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:39329fc0-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3932c8c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3932f1e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:39331b08-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:39334588-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39336e8c-7972-11ec-93d9-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3933979a-7972-11ec-93d9-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3933c094-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3933eba0-7972-11ec-93d9-0242ac110002 UniProtKB:P21127 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 11B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3934158a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ88 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39343e98-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3934681e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:39349140-7972-11ec-93d9-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:3934ba44-7972-11ec-93d9-0242ac110002 UniProtKB:Q6P3R8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase Nek5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3934e352-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39350cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:39353604-7972-11ec-93d9-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:39355f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3935882a-7972-11ec-93d9-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3935b2e6-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3935dbfe-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3936050c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39362e24-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:3936578c-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:393680b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3936a9e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3936d2fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3936fcb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:3937270c-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:39375010-7972-11ec-93d9-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:39377a04-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3937a312-7972-11ec-93d9-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3937cc3e-7972-11ec-93d9-0242ac110002 UniProtKB:O60331 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3937f65a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39381fea-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:393848e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:39387206-7972-11ec-93d9-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:39389af6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:3938c4cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.328']} DrugCentral uuid:3938edbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:393916c0-7972-11ec-93d9-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.604']} DrugCentral uuid:39393fd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.523']} DrugCentral uuid:39396c92-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:393995dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:3939befe-7972-11ec-93d9-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.292']} DrugCentral uuid:3939e870-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393a119c-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:393a3ef6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:393a3ef6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:393a77d6-7972-11ec-93d9-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:393a77d6-7972-11ec-93d9-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:393aaddc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z2V5 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393afd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:393ba14c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14833 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:393bcab4-7972-11ec-93d9-0242ac110002 UniProtKB:Q14831 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:393bf3b8-7972-11ec-93d9-0242ac110002 UniProtKB:O15303 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:393c1dd4-7972-11ec-93d9-0242ac110002 UniProtKB:O00222 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:393c46ce-7972-11ec-93d9-0242ac110002 UniProtKB:P31423 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:393c707c-7972-11ec-93d9-0242ac110002 UniProtKB:P35349 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:393c998a-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:393cc2c0-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:393cebce-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:393d1888-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:393d41c8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:393d6ae0-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.405']} DrugCentral uuid:393d9452-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:393db900-7972-11ec-93d9-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:393dddb8-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.922']} DrugCentral uuid:393e06da-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:393e3092-7972-11ec-93d9-0242ac110002 UniProtKB:P51788 biolink:molecularly_interacts_with DrugCentral:4123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubiprostone is opener of Ion channel (Chloride channel protein 2) DrugCentral uuid:393e555e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:393e7e76-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:393ea7a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:393ed182-7972-11ec-93d9-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:393efba8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:393f24d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:393f4e00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:393f77ea-7972-11ec-93d9-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:393fa10c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:393fca38-7972-11ec-93d9-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:393ff350-7972-11ec-93d9-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:39401d94-7972-11ec-93d9-0242ac110002 UniProtKB:Q94F81 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (HD2 type histone deacetylase HDA106; Histone deacetylase 2b; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:394046a2-7972-11ec-93d9-0242ac110002 UniProtKB:O09106 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:39406f92-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ZTP8 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:39409882-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:3940c366-7972-11ec-93d9-0242ac110002 UniProtKB:Q70I53 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase-like amidohydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3940ec74-7972-11ec-93d9-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:39411596-7972-11ec-93d9-0242ac110002 UniProtKB:Q7K6A1 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:39413f58-7972-11ec-93d9-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:39416866-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39419548-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:39419548-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3941ce82-7972-11ec-93d9-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3941ce82-7972-11ec-93d9-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39422bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3942dbf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3942dbf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3942dbf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3942dbf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:39432d90-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase (HDAC1 and HDAC2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39432d90-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase (HDAC1 and HDAC2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39437958-7972-11ec-93d9-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:39437958-7972-11ec-93d9-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:39437958-7972-11ec-93d9-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:39437958-7972-11ec-93d9-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:39437958-7972-11ec-93d9-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:39437958-7972-11ec-93d9-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:39437958-7972-11ec-93d9-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:3943eb4a-7972-11ec-93d9-0242ac110002 UniProtKB:A5H660 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Unclassified (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:39441458-7972-11ec-93d9-0242ac110002 UniProtKB:P24527 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:39443d66-7972-11ec-93d9-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:4125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proline targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:394468fe-7972-11ec-93d9-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:4125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proline targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:394491da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:4126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asparagine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:3944baac-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3944e428-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:39450e30-7972-11ec-93d9-0242ac110002 UniProtKB:P07314 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Gamma-glutamyltranspeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3945373e-7972-11ec-93d9-0242ac110002 UniProtKB:P63116 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Unclassified (Asc-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:39456038-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:394589a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:4128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:3945b2a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:4134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxal targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3945dbb2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:394601b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:39462748-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:39464bf6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:39467518-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:39469e26-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:3946c860-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.925']} DrugCentral uuid:3946f16e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39471a54-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:39474344-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:39476cac-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.209']} DrugCentral uuid:394795b0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:3947beb4-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.617']} DrugCentral uuid:3947e7c2-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.569']} DrugCentral uuid:394811ac-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:39483aba-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.635']} DrugCentral uuid:394863be-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:39488d8a-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:3948b6e8-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.251']} DrugCentral uuid:3948e000-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.916']} DrugCentral uuid:3949090e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.061']} DrugCentral uuid:3949337a-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:39495c88-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:39498596-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.195']} DrugCentral uuid:3949aeb8-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.265']} DrugCentral uuid:3949da00-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:394a0340-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.556']} DrugCentral uuid:394a2c44-7972-11ec-93d9-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:394a553e-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:394a7ee2-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:394aa804-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:394ad108-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:394afa84-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.809']} DrugCentral uuid:394b23a6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.975']} DrugCentral uuid:394b4cb4-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:394b75b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:394b9f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:394bc888-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.124']} DrugCentral uuid:394bf2c2-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.241']} DrugCentral uuid:394c1bda-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:394c4592-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.945']} DrugCentral uuid:394c6eaa-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:394c979a-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.294']} DrugCentral uuid:394cc0a8-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.037']} DrugCentral uuid:394cea10-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:394d131e-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.416']} DrugCentral uuid:394d3d08-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:394d6634-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:394d900a-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.084']} DrugCentral uuid:394db90e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.628']} DrugCentral uuid:394de2a8-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.012']} DrugCentral uuid:394e0c74-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:394e3578-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.233']} DrugCentral uuid:394e5e7c-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.325']} DrugCentral uuid:394e8762-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:394eb0c0-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:394ed9d8-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:394f02e6-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.701']} DrugCentral uuid:394f2bea-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 udenafil targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:394f52c8-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:4141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 udenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.084']} DrugCentral uuid:394f7bfe-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:4142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine silver is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:394fa0ca-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine silver targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:394fc9ce-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:394ff37c-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.658']} DrugCentral uuid:39501c9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.85']} DrugCentral uuid:395045a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.21']} DrugCentral uuid:39506e88-7972-11ec-93d9-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.96']} DrugCentral uuid:395097e6-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3950c112-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:3950ea02-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium lauryl sulfate targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:395112f2-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium lauryl sulfate targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:39513cb4-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:395166c6-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:39518fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3951d016-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:3951d016-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:3951d016-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:3951d016-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:3951d016-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:3951d016-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:3951d016-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:395234ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:39525e8c-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3952879a-7972-11ec-93d9-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3952b0bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3952d9ca-7972-11ec-93d9-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:395304f4-7972-11ec-93d9-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:39532e98-7972-11ec-93d9-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:395357ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:395380f0-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant is antagonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:3953aac6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3953d3d4-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:3953f8aa-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.44']} DrugCentral uuid:3954221c-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:39544b48-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:39547460-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:39549d8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q2VKV7 biolink:molecularly_interacts_with DrugCentral:4152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 permethrin is blocker of Ion channel (Sodium channel protein) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3954e256-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:39555c9a-7972-11ec-93d9-0242ac110002 UniProtKB:P39654 biolink:molecularly_interacts_with DrugCentral:4156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edaravone targets Enzyme (Polyunsaturated fatty acid lipoxygenase ALOX15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:39558990-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lercanidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:39558990-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lercanidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:3955b8ca-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:3955dd96-7972-11ec-93d9-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) DrugCentral uuid:395602b2-7972-11ec-93d9-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:39562b98-7972-11ec-93d9-0242ac110002 UniProtKB:Q00688 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP3) DrugCentral uuid:3956555a-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:3956555a-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:395684c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3956b0cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39577458-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39597942-7972-11ec-93d9-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:3959a2be-7972-11ec-93d9-0242ac110002 UniProtKB:P22462 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3959cbea-7972-11ec-93d9-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liraglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.2']} DrugCentral uuid:3959f502-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcaftadine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:395a19d8-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ulipristal is antagonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:395a44da-7972-11ec-93d9-0242ac110002 UniProtKB:O95470 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod targets Enzyme (Sphingosine-1-phosphate lyase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:395a6ff0-7972-11ec-93d9-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:395a98f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:395ac1f8-7972-11ec-93d9-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:395aebba-7972-11ec-93d9-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:395b14a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q923J1 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:395b3da4-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:395b66b2-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.195']} DrugCentral uuid:395b904c-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.305']} DrugCentral uuid:395bb950-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.967']} DrugCentral uuid:395be25e-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:395c0b8a-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:395c35a6-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.69']} DrugCentral uuid:395c5ee6-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.003']} DrugCentral uuid:395c890c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.328']} DrugCentral uuid:395cc9c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:395cc9c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:395cc9c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:395cc9c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:395cc9c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:395cc9c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:395cc9c6-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:395d2dda-7972-11ec-93d9-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:4170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tesamorelin is agonist of GPCR (Growth hormone-releasing hormone receptor) DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395d7178-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:395dfe40-7972-11ec-93d9-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:395e2744-7972-11ec-93d9-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:395e502a-7972-11ec-93d9-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:395e7910-7972-11ec-93d9-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:395ea2b4-7972-11ec-93d9-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:395ecbae-7972-11ec-93d9-0242ac110002 UniProtKB:O60911 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin L2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:395ef48a-7972-11ec-93d9-0242ac110002 UniProtKB:P43235 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin K) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:395f1d98-7972-11ec-93d9-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:395f46d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBX1 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:395f74c8-7972-11ec-93d9-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:395f74c8-7972-11ec-93d9-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:395fa9de-7972-11ec-93d9-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:395fd422-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:395ffd26-7972-11ec-93d9-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:39602616-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNI1 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Chymotrypsin-like elastase family member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:39604f06-7972-11ec-93d9-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:39607896-7972-11ec-93d9-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3960a1a4-7972-11ec-93d9-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:3960ca9e-7972-11ec-93d9-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3960f3e8-7972-11ec-93d9-0242ac110002 UniProtKB:O60911 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin L2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:39611cd8-7972-11ec-93d9-0242ac110002 UniProtKB:P43235 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin K) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:39614654-7972-11ec-93d9-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3961734a-7972-11ec-93d9-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) DrugCentral uuid:3961734a-7972-11ec-93d9-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) DrugCentral uuid:3961a392-7972-11ec-93d9-0242ac110002 UniProtKB:C1KIQ2 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3961cc78-7972-11ec-93d9-0242ac110002 UniProtKB:Q0ZMF1 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:3961f59a-7972-11ec-93d9-0242ac110002 UniProtKB:Q91RS4 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:39621e9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:39624874-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:39626d40-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3962963a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3962c088-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3962e9f0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:39631308-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:39633bf8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:396366c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:396390bc-7972-11ec-93d9-0242ac110002 UniProtKB:P97321 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3963b9c0-7972-11ec-93d9-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3963e2c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39640c5e-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:39643562-7972-11ec-93d9-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate is inhibitor of Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:39645e48-7972-11ec-93d9-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:39648742-7972-11ec-93d9-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:3964b08c-7972-11ec-93d9-0242ac110002 UniProtKB:P11715 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 17A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3964d9a4-7972-11ec-93d9-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:4177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin enacarbil is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) DrugCentral uuid:3964fe66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:4177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin enacarbil is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) DrugCentral uuid:3965231e-7972-11ec-93d9-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:39654d62-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3965765c-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:39659f56-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:3965c85a-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:3965f208-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:39661b0c-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3966441a-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:39666d28-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:396696c2-7972-11ec-93d9-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3966bfbc-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3966e94c-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3967132c-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:39673c58-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:39676656-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:39678f5a-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3967b8ea-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3967e1ee-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:39680ad4-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:396833d8-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:39685d2c-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:39688630-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:3968b02e-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3968d946-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:39690506-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:39692e00-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:396956f0-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3969806c-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3969a966-7972-11ec-93d9-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3969d256-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3969fb50-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:396a249a-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:396a4d94-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:396a768e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:396a9f74-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:396aca26-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:396af334-7972-11ec-93d9-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:396b1c38-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:396b4532-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:396b6fa8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:396b988e-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:396bc19c-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:396beaa0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:396c1426-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:396c3d34-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:396c662e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:396c90b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:396cba34-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:396ce32e-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.34']} DrugCentral uuid:396d0c46-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:396d3590-7972-11ec-93d9-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:396d5e94-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:396d8810-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:396db114-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:396dda90-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:396e036c-7972-11ec-93d9-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:396e2c52-7972-11ec-93d9-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:396e554c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:396e81e8-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:396eac36-7972-11ec-93d9-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:396ed53a-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:396efe98-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:396f2788-7972-11ec-93d9-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:396f508c-7972-11ec-93d9-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:396f7a76-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:396fa3d4-7972-11ec-93d9-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:396fcce2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:396ff5d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:39701ec2-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:397049ec-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3970730e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:39709c08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3970c502-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3970ee60-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:39711750-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:39714040-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:39716944-7972-11ec-93d9-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39719284-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:3971bb92-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3971e496-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:39720ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:39723856-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:39726164-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:39728a68-7972-11ec-93d9-0242ac110002 UniProtKB:Q5VT25 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3972b3bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3972dcac-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:397305a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:39732e8c-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:397357f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:397381de-7972-11ec-93d9-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3973aaec-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3973d404-7972-11ec-93d9-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:3973ff10-7972-11ec-93d9-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3974280a-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:397451a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:39747a9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3974a406-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3974ce18-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3974f71c-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3975205c-7972-11ec-93d9-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:39754956-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3975723c-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:39759b22-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:3975c64c-7972-11ec-93d9-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3975ef5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:39761840-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3976411c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:39766a66-7972-11ec-93d9-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:39769356-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3976bc46-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:3976f13e-7972-11ec-93d9-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:3976f13e-7972-11ec-93d9-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:3976f13e-7972-11ec-93d9-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:3976f13e-7972-11ec-93d9-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:39773572-7972-11ec-93d9-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:39775f5c-7972-11ec-93d9-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:39778950-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3977b43e-7972-11ec-93d9-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3977dd38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z351 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine targets Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39780650-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:39782fb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:397858a8-7972-11ec-93d9-0242ac110002 UniProtKB:O19045 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:397881a2-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:3978aad8-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3978d436-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3978fd08-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:397925f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:39794f06-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor is negative allosteric modulator of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:39797ae4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor is inhibitor of Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3979a3d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EPX4 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor targets GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3979ccb0-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3979f5c8-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:397a1f26-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:397a482a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:397a726e-7972-11ec-93d9-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:397a9c44-7972-11ec-93d9-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:397ac534-7972-11ec-93d9-0242ac110002 UniProtKB:P22830 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Enzyme (Ferrochelatase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:397aee6a-7972-11ec-93d9-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:397b176e-7972-11ec-93d9-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:397b41f8-7972-11ec-93d9-0242ac110002 UniProtKB:P25023 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.11']} DrugCentral uuid:397b6bec-7972-11ec-93d9-0242ac110002 UniProtKB:O70526 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.96']} DrugCentral uuid:397b94e6-7972-11ec-93d9-0242ac110002 UniProtKB:P46663 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B1 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:397bbdea-7972-11ec-93d9-0242ac110002 UniProtKB:P32299 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:397be766-7972-11ec-93d9-0242ac110002 UniProtKB:P97583 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B1 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:397c1074-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:397c3978-7972-11ec-93d9-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:397c6272-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:397c8be4-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:397cb4d4-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:397cddd8-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:397d079a-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:397d3116-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:397d5a24-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:397d8328-7972-11ec-93d9-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:397dac90-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:397dd594-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:397dfea2-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:397e279c-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:397e5118-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:397e7a26-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:397ea320-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:397ecc24-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:397ef80c-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:397f2188-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:397f4a96-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:397f7480-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:397f9e1a-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:397fc714-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:397ff00e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3980198a-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:398042a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:39806bb0-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.26']} DrugCentral uuid:398095e0-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3980c042-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3980e928-7972-11ec-93d9-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3981122c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:39813bb2-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.36']} DrugCentral uuid:3981651a-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:39818e32-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3981b722-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3981e030-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:39820998-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3982329c-7972-11ec-93d9-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:39825ba0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:39828580-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3982aeac-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3982d7ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.13']} DrugCentral uuid:398300e6-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:39832a30-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:39835320-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:39837d28-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3983a62c-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3983cf94-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3983f88e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3984219c-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:39844ab4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:398474a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:39849db6-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3984c6b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:3984efb4-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:39851912-7972-11ec-93d9-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3985423e-7972-11ec-93d9-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:39856b4c-7972-11ec-93d9-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3985950e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3985be12-7972-11ec-93d9-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3985e716-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3986101a-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:39863a2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:3986633a-7972-11ec-93d9-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:39868d60-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3986b664-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3986dfea-7972-11ec-93d9-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:398708ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:398731fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:39875af6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:3987859e-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3987ae98-7972-11ec-93d9-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3987d79c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:39880118-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:39882b3e-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:39885438-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:39887d3c-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3988a6b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3988cfc6-7972-11ec-93d9-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3988f8c0-7972-11ec-93d9-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:398921b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:39894b72-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:39897476-7972-11ec-93d9-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:39899d70-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:3989c674-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3989f202-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:398a1b1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:398a4428-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:398a6d36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:398a969e-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:398abfac-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:398ae8a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:398b1272-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:398b3b76-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:398b6466-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:398b8e64-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:398bb8da-7972-11ec-93d9-0242ac110002 UniProtKB:P21127 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 11B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:398be53a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ88 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:398c0e3e-7972-11ec-93d9-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:398c3756-7972-11ec-93d9-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:398c60be-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:398c89c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD19 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase Nek9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:398cb3e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:398cdd0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:398d06ae-7972-11ec-93d9-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:398d2fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:398d58c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:398d826e-7972-11ec-93d9-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:398dabea-7972-11ec-93d9-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:398dd4e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:398dfde8-7972-11ec-93d9-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:398e275a-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:398e505e-7972-11ec-93d9-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:398e794e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:398ea248-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:398ecc14-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:398ef57c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:398f1e76-7972-11ec-93d9-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:398f4770-7972-11ec-93d9-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:398f71fa-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:398f9bf8-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:398fc510-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:398fee0a-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:39901786-7972-11ec-93d9-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:39904094-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:39906998-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:39909350-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3990bc40-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3990e53a-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39910e48-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:399138be-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:399164ec-7972-11ec-93d9-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:39918fa8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3991b8ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3991e214-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:39920b2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:39923426-7972-11ec-93d9-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:39925d2a-7972-11ec-93d9-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:399286d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3992b108-7972-11ec-93d9-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3992d9ee-7972-11ec-93d9-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:39930432-7972-11ec-93d9-0242ac110002 UniProtKB:Q62190 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:39932dae-7972-11ec-93d9-0242ac110002 UniProtKB:Q02858 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:3993569e-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39938088-7972-11ec-93d9-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3993a9dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3993d2cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3993fbd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:399428b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:399428b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:39945e9a-7972-11ec-93d9-0242ac110002 UniProtKB:O15357 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Enzyme (Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3994879e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3994b0ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NB16 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mixed lineage kinase domain-like protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3994da82-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:399503a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:4188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferiprone targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:39952d20-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:3995562e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.261']} DrugCentral uuid:39957f96-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.573']} DrugCentral uuid:3995a89a-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3995d1b2-7972-11ec-93d9-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3995faca-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.501']} DrugCentral uuid:3996246e-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:39964d90-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:399676da-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.664']} DrugCentral uuid:3996a006-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3996c9d2-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3996f2ea-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:39971bee-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39974632-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:39976f36-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:39979830-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3997c120-7972-11ec-93d9-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:3997eaf6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:399813fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:39983cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3998660c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3998928a-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:3998bc1a-7972-11ec-93d9-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3998e514-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:39990e2c-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:39993794-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.44']} DrugCentral uuid:399960a2-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:399989b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:3999b2aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3999dc6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:399a0598-7972-11ec-93d9-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:399a2e92-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:399a58b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:399a84fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:399aae1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:399ad716-7972-11ec-93d9-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:399b0088-7972-11ec-93d9-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:399b2a7c-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:399b53f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:399b7ce8-7972-11ec-93d9-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:399ba6aa-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:399bcfae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:399bf8a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:399c2198-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:399c4e52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:399c7742-7972-11ec-93d9-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:399ca028-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:399cc986-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:399cf280-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:399d1b70-7972-11ec-93d9-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:399d446a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:399d6e04-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:399d9712-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:399dc020-7972-11ec-93d9-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:399de92e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:399e130e-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:399e3c30-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:399e6516-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:399e8e10-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:399eb8c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:399ee1c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:399f0ade-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:399f354a-7972-11ec-93d9-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:399f5e62-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:399f8770-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:399fb074-7972-11ec-93d9-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:399fda40-7972-11ec-93d9-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:39a00330-7972-11ec-93d9-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39a02c48-7972-11ec-93d9-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:39a05542-7972-11ec-93d9-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39a07eaa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39a0a7a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:39a0d0b2-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39a0f9ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:39a1238c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:39a14c90-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:39a17594-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:39a19ea2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:39a1c9ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39a1f2da-7972-11ec-93d9-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:39a21c74-7972-11ec-93d9-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39a245d2-7972-11ec-93d9-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:39a26ecc-7972-11ec-93d9-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:39a297d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:39a2c0d4-7972-11ec-93d9-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:39a2ea5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:39a31354-7972-11ec-93d9-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:39a33d52-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:39a36660-7972-11ec-93d9-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:39a3916c-7972-11ec-93d9-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39a3ba70-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39a3e356-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:39a40c64-7972-11ec-93d9-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:39a435cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:39a45ee4-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39a487de-7972-11ec-93d9-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:39a4b218-7972-11ec-93d9-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:39a4db9e-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:39a504ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:39a52da6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:39a557d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39a580d0-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:39a5a9ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:39a5d2ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:39a5fc36-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:39a62526-7972-11ec-93d9-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39a64e16-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39a67706-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:39a6a0b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:39a6c9b8-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:39a6f2bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39a71c92-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:39a74834-7972-11ec-93d9-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:39a7712e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:39a79a1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:39a7c3a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:39a7ecbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39a815c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:39a83eba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:39a86868-7972-11ec-93d9-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:39a89180-7972-11ec-93d9-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:39a8bb10-7972-11ec-93d9-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:39a8e41e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:39a90f48-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39a93856-7972-11ec-93d9-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39a9615a-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39a98a5e-7972-11ec-93d9-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:39a9b3c6-7972-11ec-93d9-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:39a9dcd4-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:39aa05d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:39aa2ed2-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:39aa5894-7972-11ec-93d9-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:39aa8184-7972-11ec-93d9-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:39aaae48-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:39aaae48-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:39aaeb1a-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:39aaeb1a-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:39ab2562-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:39ab2562-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:39ab6220-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:39ab6220-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:39ab6220-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:39aba7d0-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:39aba7d0-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:39abdcdc-7972-11ec-93d9-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:39ac0680-7972-11ec-93d9-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:39ac2fa2-7972-11ec-93d9-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:39ac589c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:39ac818c-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.393']} DrugCentral uuid:39acabd0-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.401']} DrugCentral uuid:39acd4de-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.271']} DrugCentral uuid:39acfde2-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.187']} DrugCentral uuid:39ad26d2-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:39ad5058-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.936']} DrugCentral uuid:39ad7966-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:39ada256-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.627']} DrugCentral uuid:39adcb78-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is binding agent of Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.812']} DrugCentral uuid:39adf526-7972-11ec-93d9-0242ac110002 UniProtKB:Q99707 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methionine synthase) DrugCentral uuid:39ae19e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBK8 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methionine synthase reductase) DrugCentral uuid:39ae3e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BXJ7 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Unclassified (Protein amnionless) DrugCentral uuid:39ae633a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96EY8 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial) DrugCentral uuid:39ae89c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH4 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methylmalonic aciduria type A protein, mitochondrial) DrugCentral uuid:39aeafe8-7972-11ec-93d9-0242ac110002 UniProtKB:P20062 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Secreted (Transcobalamin-2) DrugCentral uuid:39aed48c-7972-11ec-93d9-0242ac110002 UniProtKB:P20061 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Secreted (Transcobalamin-1) DrugCentral uuid:39aef94e-7972-11ec-93d9-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:4197 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vitamin A palmitate targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:39af2298-7972-11ec-93d9-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:4197 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vitamin A palmitate targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:39af4ba6-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4199 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium chloride targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:39af74be-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium acetate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:39af9dcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium acetate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.44']} DrugCentral uuid:39afcb6c-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:39afcb6c-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:39affbe6-7972-11ec-93d9-0242ac110002 UniProtKB:P29218 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Enzyme (Inositol-1(or 4)-monophosphatase 1) DrugCentral uuid:39b0209e-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:39b049b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:39b07350-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:39b09c68-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.582']} DrugCentral uuid:39b0c594-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:39b0ef10-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:39b11828-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:39b14136-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:39b16a44-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:39b193ca-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:39b1bcec-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:39b1e5f0-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:39b20efe-7972-11ec-93d9-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:39b239d8-7972-11ec-93d9-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.157']} DrugCentral uuid:39b262e6-7972-11ec-93d9-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.394']} DrugCentral uuid:39b28bcc-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:39b2b598-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:39b2df14-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:39b3082c-7972-11ec-93d9-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:39b33144-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:39b35ad4-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:39b383c4-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:39b3acd2-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:39b3d5ea-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:39b3ffac-7972-11ec-93d9-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:39b428ba-7972-11ec-93d9-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:39b45254-7972-11ec-93d9-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:39b47b62-7972-11ec-93d9-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:39b4a4d4-7972-11ec-93d9-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:39b4cdba-7972-11ec-93d9-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:39b4f6aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:39b52742-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:39b52742-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:39b52742-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:39b570c6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:39b570c6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:39b570c6-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:39b5bb12-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:39b5bb12-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:39b5bb12-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:39b60478-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:39b60478-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:39b60478-7972-11ec-93d9-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:39b64e88-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:39b64e88-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:39b64e88-7972-11ec-93d9-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:39b69032-7972-11ec-93d9-0242ac110002 UniProtKB:P02665 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Unclassified (Beta-casein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:39b6b936-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:39b6e258-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:39b70c06-7972-11ec-93d9-0242ac110002 UniProtKB:O15552 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid is agonist of GPCR (Free fatty acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:39b73500-7972-11ec-93d9-0242ac110002 UniProtKB:O14843 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets GPCR (Free fatty acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:39b75e04-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:39b782b2-7972-11ec-93d9-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:4213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone acetate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:39b7b584-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:39b7b584-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:39b7b584-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:39b7f260-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium phosphate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:39b81b78-7972-11ec-93d9-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:4220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telbivudine targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:39b844e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:4220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telbivudine is inhibitor of Polyprotein (Protein P) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:39b86dd0-7972-11ec-93d9-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4221 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequinol is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:39b89288-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:39b8bb8c-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:39b8e530-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:39b90e3e-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:39b9374c-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:39b96050-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:39b98b8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:39b9b62c-7972-11ec-93d9-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:39b9e016-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:39ba0938-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:39ba32b4-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:39ba5c12-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:39ba850c-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:39baaea6-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:39bad8cc-7972-11ec-93d9-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39bb01bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:39bb2ac0-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:39bb5540-7972-11ec-93d9-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:39bb7ebc-7972-11ec-93d9-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:39bba798-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:39bbd470-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:39bbd470-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:39bc119c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:39bc119c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:39bc119c-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:39bc5a4e-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39bc5a4e-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39bc5a4e-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39bc9c2a-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:39bcc538-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39bcee50-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:39bd1736-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:39bd40f8-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.31']} DrugCentral uuid:39bd6ad8-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:39bd93e6-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39bdbd62-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39bde670-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:39be0f92-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:39be38c8-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:39be626c-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:39be8b84-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:39beb488-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:39bedd6e-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.29']} DrugCentral uuid:39bf071c-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:39bf3020-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:39bf5924-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:39bf8228-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39bfab86-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:39bfd480-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39bffd70-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:39c0266a-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:39c0516c-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39c07a84-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:39c0a37e-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:39c0cdcc-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39c0f720-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:39c12038-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.89']} DrugCentral uuid:39c149d2-7972-11ec-93d9-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:39c1743e-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:39c19d38-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:39c1c63c-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:39c1ef2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:39c218d0-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39c241d4-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:39c26aba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:39c293be-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:39c2bd94-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:39c2e684-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39c30f74-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:39c338dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:39c361e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:39c38ada-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:39c3b3d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:39c3dd6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:39c40668-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:39c42f8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:39c45884-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39c483ae-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:39c4ad16-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39c4d61a-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:39c4ff1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39c52886-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39c55176-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39c57b88-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:39c5a478-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:39c5ce3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:39c5f734-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39c62038-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:39c64a22-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:39c674ca-7972-11ec-93d9-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:39c69dce-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:39c6c6dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39c6f01c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:39c71920-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:39c74224-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:39c76b32-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:39c794ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39c7be02-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:39c7e6f2-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39c81028-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:39c83ada-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:39c863d4-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:39c88ce2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:39c8b62c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:39c8df30-7972-11ec-93d9-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:39c9083e-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:39c93142-7972-11ec-93d9-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:39c95ae6-7972-11ec-93d9-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:39c984c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:39c9adca-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:39c9d6c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39ca01d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:39ca2b06-7972-11ec-93d9-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:39ca541e-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:39ca7d36-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:39caa6a8-7972-11ec-93d9-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:39cacf98-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39caf8a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:39cb21a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:39cb4b44-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:39cb7452-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:39cb9d6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:39cbc786-7972-11ec-93d9-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:39cbf08a-7972-11ec-93d9-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:39cc1984-7972-11ec-93d9-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:39cc4288-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:39cc6be6-7972-11ec-93d9-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:39cc9616-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:39ccbf2e-7972-11ec-93d9-0242ac110002 UniProtKB:P05129 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate is activator of Kinase (Protein kinase C gamma type) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.79']} DrugCentral uuid:39cce83c-7972-11ec-93d9-0242ac110002 UniProtKB:P05771 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C beta type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.836']} DrugCentral uuid:39cd11d6-7972-11ec-93d9-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.197']} DrugCentral uuid:39cd3abc-7972-11ec-93d9-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:39cd63a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:39cd8d82-7972-11ec-93d9-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate is activator of Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.328']} DrugCentral uuid:39cdb910-7972-11ec-93d9-0242ac110002 UniProtKB:Q62226 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:39cde20a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15465 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:39ce0b18-7972-11ec-93d9-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib is inhibitor of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.79']} DrugCentral uuid:39ce3480-7972-11ec-93d9-0242ac110002 UniProtKB:P56726 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:39ce5e1a-7972-11ec-93d9-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:4228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivacaftor is positive modulator of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:39ce8714-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:4229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafluprost is agonist of GPCR (Prostaglandin F2-alpha receptor) DrugCentral uuid:39ceabcc-7972-11ec-93d9-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:4234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginesatide is agonist of Membrane receptor (Erythropoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.43']} DrugCentral uuid:39ced58e-7972-11ec-93d9-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avobenzone is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:39cefa5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:39cf2340-7972-11ec-93d9-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:39cf4c44-7972-11ec-93d9-0242ac110002 UniProtKB:O95237 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Enzyme (Lecithin retinol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:39cf762e-7972-11ec-93d9-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.81']} DrugCentral uuid:39cf9f1e-7972-11ec-93d9-0242ac110002 UniProtKB:P48442 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:39cfc822-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:39cff144-7972-11ec-93d9-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:39d01ab6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:39d043d8-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:39d06cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P51787 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:39d095fe-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:39d0bf98-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:39d0e8ba-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:39d111d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:39d13acc-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:39d16524-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:39d18f40-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:39d1b858-7972-11ec-93d9-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:39d1e1c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:39d20ede-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bismuth subsalicylate is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:39d20ede-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bismuth subsalicylate is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:39d23e40-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:39d26898-7972-11ec-93d9-0242ac110002 UniProtKB:Q8R455 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:39d29250-7972-11ec-93d9-0242ac110002 UniProtKB:Q4QYD9 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Unclassified (Heat sensitive channel TRPV3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:39d2bb5e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfur targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:39d2e444-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfur targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:39d30d52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:4264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamide targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:39d33958-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:39d36270-7972-11ec-93d9-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:39d38b7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:39d3b4f0-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:39d3de76-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:39d40798-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:39d4309c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:39d45a40-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:39d48330-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39d4ac3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:39d4d52e-7972-11ec-93d9-0242ac110002 UniProtKB:P00720 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Endolysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:39d4ffae-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:39d528a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:39d551c0-7972-11ec-93d9-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:39d57ace-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:39d5a508-7972-11ec-93d9-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:39d5ce0c-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:39d5f72e-7972-11ec-93d9-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:39d62014-7972-11ec-93d9-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:39d649ae-7972-11ec-93d9-0242ac110002 UniProtKB:P11344 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:39d67320-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d71dd4-7972-11ec-93d9-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:39d8aa1e-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:39d8d34a-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:39d8fc6c-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:39d92552-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:39d94ea6-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Florbetapir F-18 targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:39d977b4-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:39d9a086-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:39d9c980-7972-11ec-93d9-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:39d9f324-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:39da1c28-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:39da4540-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDS5 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets GPCR (Oxoeicosanoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39da6f34-7972-11ec-93d9-0242ac110002 UniProtKB:Q6RI86 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:39da98a6-7972-11ec-93d9-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Nuclear other (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:39dac2d6-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium iodide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:39daebf8-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39db1588-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:39db3eb4-7972-11ec-93d9-0242ac110002 UniProtKB:O19045 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:39db7348-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:39db7348-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:39db7348-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:39db7348-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:39dbc28a-7972-11ec-93d9-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39dbeb98-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:39dc14a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:39dc3e2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:39dc678a-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Flutemetamol (18F) targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:39dc90c0-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.69']} DrugCentral uuid:39dcb9ec-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.25']} DrugCentral uuid:39dce372-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:39dd0c94-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:39dd35b6-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.91']} DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39dd81ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:39de0464-7972-11ec-93d9-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:39de2ebc-7972-11ec-93d9-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:39de57de-7972-11ec-93d9-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:39de80ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WWX8 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/myo-inositol cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:39deaaae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY91 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Low affinity sodium-glucose cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.87']} DrugCentral uuid:39ded43e-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:39defd24-7972-11ec-93d9-0242ac110002 UniProtKB:P51160 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.201']} DrugCentral uuid:39df261e-7972-11ec-93d9-0242ac110002 UniProtKB:O77746 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:39df53b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:39df53b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:39df8a50-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:39dfb354-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene is agonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:39dfdd02-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:39e0080e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:39e0311c-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:39e05a3e-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:39e083b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:39e0acd2-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:39e0d5e0-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:39e0fed0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:39e1287e-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:39e1518c-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:39e17aa4-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:39e1a3bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:39e1cdec-7972-11ec-93d9-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:39e1f6d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39e21fe0-7972-11ec-93d9-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:39e24902-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:39e27256-7972-11ec-93d9-0242ac110002 UniProtKB:Q16555 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Dihydropyrimidinase-related protein 2) DrugCentral uuid:39e297fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:39e2c0e4-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:39e2ea06-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39e313c8-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:39e33ccc-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:39e3659e-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:39e38e8e-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:39e3c7fa-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:39e3c7fa-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:39e3c7fa-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:39e3c7fa-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:39e3c7fa-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:39e42146-7972-11ec-93d9-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:39e44a9a-7972-11ec-93d9-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:39e47362-7972-11ec-93d9-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:39e49c52-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:39e4c574-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:39e4f080-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:39e5198e-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:39e54292-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:39e56cf4-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:39e595f8-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:39e5befc-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39e5e81e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:39e61190-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:39e63b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39e66532-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39e68e4a-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:39e6b802-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:39e6e0fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:39e70a14-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39e7332c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39e75d0c-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:39e785fc-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:39e7af00-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:39e7d87c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:39e80194-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:39e82a84-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:39e85392-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:39e87d54-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39e8a66c-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39e8cf7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:39e8f892-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39e92290-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:39e94bbc-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:39e974c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:39e99dec-7972-11ec-93d9-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39e9c74a-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39e9f06c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:39ea1966-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:39ea43c8-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:39ea6d80-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:39ea96a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39eabfb0-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:4322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azilsartan medoxomil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:39eae9d6-7972-11ec-93d9-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:4322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azilsartan medoxomil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:39eb141a-7972-11ec-93d9-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:39eb3d1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:39eb6636-7972-11ec-93d9-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:39eb8f9e-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:39ebb8c0-7972-11ec-93d9-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:39ebe1d8-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:39ec0ad2-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:39ec34b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant is antagonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.52']} DrugCentral uuid:39ec5db6-7972-11ec-93d9-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:39ec86ba-7972-11ec-93d9-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:39ecafc8-7972-11ec-93d9-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:39ecda66-7972-11ec-93d9-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:39ed0360-7972-11ec-93d9-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:39ed2cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bazedoxifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:39ed5680-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bazedoxifene is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39ee13e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:39efd6f8-7972-11ec-93d9-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambrisentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:39f0001a-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambrisentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.65']} DrugCentral uuid:39f02950-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alogliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:39f05272-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:4342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zucapsaicin is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.71']} DrugCentral uuid:39f07ca2-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.158']} DrugCentral uuid:39f0a5ce-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.936']} DrugCentral uuid:39f0cedc-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39f0f7e0-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.726']} DrugCentral uuid:39f12134-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.363']} DrugCentral uuid:39f14a60-7972-11ec-93d9-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.958']} DrugCentral uuid:39f17350-7972-11ec-93d9-0242ac110002 UniProtKB:O43194 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets GPCR (G-protein coupled receptor 39) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:39f19cc2-7972-11ec-93d9-0242ac110002 UniProtKB:A6QR73 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets GPCR (G protein-coupled receptor 39-1b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:39f1c5bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPD8 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Unclassified (Ubiquitin-conjugating enzyme E2 T) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:39f1eec0-7972-11ec-93d9-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:39f22ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:39f22ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:39f22ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:39f22ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:39f22ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:39f22ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:39f22ed0-7972-11ec-93d9-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:39f2955a-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.5']} DrugCentral uuid:39f2be54-7972-11ec-93d9-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Enzyme (Thioredoxin reductase 1, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:39f2e7bc-7972-11ec-93d9-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.85']} DrugCentral uuid:39f311ba-7972-11ec-93d9-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.85']} DrugCentral uuid:39f33ab4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6N5 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Unclassified (Sulfide:quinone oxidoreductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:39f363d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bilastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:39f38e38-7972-11ec-93d9-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:4357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anidulafungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:39f3b73c-7972-11ec-93d9-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:4358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine glutamate targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:39f3e040-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39f40958-7972-11ec-93d9-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:39f43392-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:39f45cb4-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.54']} DrugCentral uuid:39f485c2-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:39f4af2a-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:39f4d838-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:39f50132-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.23']} DrugCentral uuid:39f52a2c-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:39f553d0-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:39f57cd4-7972-11ec-93d9-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:39f5a5d8-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:39f5cef0-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:39f5faa6-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:39f6240e-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:39f64d08-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:39f67616-7972-11ec-93d9-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:39f69f9c-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:39f6c8be-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:39f6f19a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:39f71c4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:39f74564-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.47']} DrugCentral uuid:39f76e72-7972-11ec-93d9-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:39f79776-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:39f7c214-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:39f7ebf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:39f8150c-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:39f83e1a-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:39f868ae-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:39f891bc-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:39f8bad4-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:39f8e3e2-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:39f90d9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:39f9369e-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:39f95f8e-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:39f9889c-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.38']} DrugCentral uuid:39f9b290-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:39f9db94-7972-11ec-93d9-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:39fa048e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:39fa2e0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:39fa572c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:39fa803a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:39faa934-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:39fad378-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:39fafc72-7972-11ec-93d9-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:39fb2666-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:39fb4f56-7972-11ec-93d9-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:39fb7b34-7972-11ec-93d9-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:39fba67c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:39fbcf94-7972-11ec-93d9-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:39fbf88e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:39fc2214-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:39fc4b18-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:39fc7412-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:39fc9dc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:39fcc6c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:39fcefbe-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:39fd18cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:39fd42e8-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:39fd6c00-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:39fd950e-7972-11ec-93d9-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:39fdbe26-7972-11ec-93d9-0242ac110002 UniProtKB:P49761 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:39fde784-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:39fe1092-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:39fe39a0-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.89']} DrugCentral uuid:39fe63ee-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:39fe8d9c-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:39feb6b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:39fedfae-7972-11ec-93d9-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:39ff0998-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:39ff33e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:39ff5cfe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.33']} DrugCentral uuid:39ff85ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:39ffaf60-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:39ffd878-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3a00017c-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.04']} DrugCentral uuid:3a002a80-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3a005424-7972-11ec-93d9-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3a007d3c-7972-11ec-93d9-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3a00a654-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3a00cf62-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:3a00fa00-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3a012318-7972-11ec-93d9-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3a014c26-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:3a017516-7972-11ec-93d9-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3a019e9c-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3a01c818-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a01f130-7972-11ec-93d9-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3a021ade-7972-11ec-93d9-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:3a0243f6-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a026d04-7972-11ec-93d9-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3a02961c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3a02c0b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3a02ea2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3a03131c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3a033d24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3a036682-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:3a038f86-7972-11ec-93d9-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3a03b88a-7972-11ec-93d9-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3a03e184-7972-11ec-93d9-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3a040b1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3a04342c-7972-11ec-93d9-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:3a045d30-7972-11ec-93d9-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3a04886e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3a04b1cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3a04dae4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3a0503d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N752 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform alpha-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3a052d32-7972-11ec-93d9-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3a05564a-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3a057f44-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3a05a8a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3a05d232-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3a05fb40-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:3a06244e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3a064d70-7972-11ec-93d9-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3a0678ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:3a06a1f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3a06cb06-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3a06f400-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3a071d72-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3a074770-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:3a077088-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3a079a04-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3a07c312-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3a07ec20-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:3a081542-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3a083f90-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3a0868b2-7972-11ec-93d9-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3a0891ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q99640 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3a08bb50-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.29']} DrugCentral uuid:3a08e4fe-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:3a090df8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3a093706-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:3a09601e-7972-11ec-93d9-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3a098b34-7972-11ec-93d9-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3a09b438-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3a09dd3c-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3a0a073a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3a0a3084-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3a0a5988-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3a0a8296-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3a0aad66-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3a0ad674-7972-11ec-93d9-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3a0aff64-7972-11ec-93d9-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a0b2868-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3a0b52e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3a0b7c0a-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3a0ba522-7972-11ec-93d9-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3a0bce26-7972-11ec-93d9-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3a0bf978-7972-11ec-93d9-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3a0c2272-7972-11ec-93d9-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3a0c4b80-7972-11ec-93d9-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3a0c7484-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:3a0c9e32-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.49']} DrugCentral uuid:3a0cc740-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3a0cf03a-7972-11ec-93d9-0242ac110002 UniProtKB:P16277 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:3a0d19ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3a0d429c-7972-11ec-93d9-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3a0d6baa-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3a0d94a4-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3a0dbe98-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3a0de7a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a0e10a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3a0e39a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3a0e633e-7972-11ec-93d9-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3a0e8c38-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3a0eb550-7972-11ec-93d9-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:3a0ede54-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3a0f0834-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:3a0f312e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3a0f5b36-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3a0f8520-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3a0fb1f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3a0fdb4c-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3a100450-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3a102dae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3a1056a8-7972-11ec-93d9-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a107fac-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:3a10a8ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:3a10d394-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3a10fcac-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3a1125a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3a114eb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a117998-7972-11ec-93d9-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3a11a2b0-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.11']} DrugCentral uuid:3a11cbaa-7972-11ec-93d9-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3a11f530-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:3a121e2a-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3a124738-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3a127050-7972-11ec-93d9-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3a1299f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3a12c2ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3a12ec10-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQI3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3a131514-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a133f8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:3a136988-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3a13928c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3a13bb9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3a13e520-7972-11ec-93d9-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3a1411e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3a1411e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3a144ad8-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3a144ad8-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3a14849e-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3a14849e-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3a14b9be-7972-11ec-93d9-0242ac110002 UniProtKB:Q05193 biolink:molecularly_interacts_with DrugCentral:4360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrimide targets Structural (Dynamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3a14e2ae-7972-11ec-93d9-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:3a150c84-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is agonist of Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3a15357e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3a155e50-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:4362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chiniofon targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3a158754-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:3a15b0a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3a15d9b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZV8 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3a1602ec-7972-11ec-93d9-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.875']} DrugCentral uuid:3a162c68-7972-11ec-93d9-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:4366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voclosporin is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3a165634-7972-11ec-93d9-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:4366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voclosporin is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3a167f2e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3a16a97c-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:3a16d294-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.61']} DrugCentral uuid:3a16ff80-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:3a1729d8-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:3a1752e6-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:3a177c6c-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:3a17a57a-7972-11ec-93d9-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3a17ce74-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3a17f76e-7972-11ec-93d9-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3a18213a-7972-11ec-93d9-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3a184a48-7972-11ec-93d9-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3a187342-7972-11ec-93d9-0242ac110002 UniProtKB:P29973 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (cGMP-gated cation channel alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3a189c32-7972-11ec-93d9-0242ac110002 UniProtKB:Q16280 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Cyclic nucleotide-gated olfactory channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3a18c5fe-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:4379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 degarelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:3a18ef2a-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.325']} DrugCentral uuid:3a19184c-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:3a194146-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3a196ac2-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapoxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.95']} DrugCentral uuid:3a1993ee-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirabegron is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.65']} DrugCentral uuid:3a19bcfc-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3a19e6e6-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3a1a101c-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3a1a3948-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3a1a6260-7972-11ec-93d9-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:3a1a8c04-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:3a1ab4f4-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3a1ade20-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3a1b0828-7972-11ec-93d9-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:3a1b319a-7972-11ec-93d9-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:3a1b5abc-7972-11ec-93d9-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3a1b83de-7972-11ec-93d9-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:3a1bb0de-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3a1bb0de-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3a1beb26-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:3a1beb26-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:3a1c2604-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a1c2604-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a1c2604-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a1c2604-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a1c7816-7972-11ec-93d9-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3a1caeda-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a1caeda-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a1caeda-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a1caeda-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a1d0060-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:3a1d0060-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:3a1d3d32-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3a1d3d32-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3a1d3d32-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3a1d7e5a-7972-11ec-93d9-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:3a1da844-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.026']} DrugCentral uuid:3a1dd148-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:3a1dfb3c-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3a1e244a-7972-11ec-93d9-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:3a1e4b0a-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3a1e740e-7972-11ec-93d9-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:3a1e98bc-7972-11ec-93d9-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:3a1ebd60-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.582']} DrugCentral uuid:3a1ee6c8-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.639']} DrugCentral uuid:3a1f0fe0-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.321']} DrugCentral uuid:3a1f38f8-7972-11ec-93d9-0242ac110002 UniProtKB:P25025 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (C-X-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.024']} DrugCentral uuid:3a1f62ba-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.029']} DrugCentral uuid:3a1f8bbe-7972-11ec-93d9-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.154']} DrugCentral uuid:3a1fb4d6-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.335']} DrugCentral uuid:3a1fddd0-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.219']} DrugCentral uuid:3a200800-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofenotane targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:3a203118-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopenthixol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3a205a30-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltrombopag targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3a20833e-7972-11ec-93d9-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:4399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3a20ac92-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:4401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casopitant targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:3a20d5aa-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casopitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:3a20fed6-7972-11ec-93d9-0242ac110002 UniProtKB:Q7DHH4 biolink:molecularly_interacts_with DrugCentral:4402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftobiprole medocaril targets Enzyme (MecA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3a2127d0-7972-11ec-93d9-0242ac110002 UniProtKB:P61073 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is partial agonist of GPCR (C-X-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3a2152b4-7972-11ec-93d9-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:3a217b9a-7972-11ec-93d9-0242ac110002 UniProtKB:P48061 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets Cytokine (Stromal cell-derived factor 1) DrugCentral uuid:3a21a05c-7972-11ec-93d9-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is antagonist of GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3a21c956-7972-11ec-93d9-0242ac110002 UniProtKB:O08565 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets GPCR (C-X-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:3a21f5ca-7972-11ec-93d9-0242ac110002 UniProtKB:P25106 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is agonist of GPCR (Atypical chemokine receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3a222090-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.118']} DrugCentral uuid:3a2249a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.157']} DrugCentral uuid:3a227324-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:3a229c28-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.308']} DrugCentral uuid:3a22c52c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.977']} DrugCentral uuid:3a22ee3a-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.915']} DrugCentral uuid:3a2317f2-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.677']} DrugCentral uuid:3a23411e-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:3a236a4a-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.085']} DrugCentral uuid:3a23934e-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.478']} DrugCentral uuid:3a23be50-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:3a23e772-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.262']} DrugCentral uuid:3a241062-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:3a243970-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.126']} DrugCentral uuid:3a2462e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.131']} DrugCentral uuid:3a248c04-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.781']} DrugCentral uuid:3a24b51c-7972-11ec-93d9-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.065']} DrugCentral uuid:3a24de2a-7972-11ec-93d9-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.931']} DrugCentral uuid:3a2507ec-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:3a253122-7972-11ec-93d9-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3a255a44-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3a2584b0-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibutylphthalate is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3a25adfa-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3a25d6f4-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3a260110-7972-11ec-93d9-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3a262a82-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:3a265372-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.018']} DrugCentral uuid:3a267c6c-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.652']} DrugCentral uuid:3a26a552-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.092']} DrugCentral uuid:3a26ceba-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.604']} DrugCentral uuid:3a26f7b4-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.775']} DrugCentral uuid:3a2720f4-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3a274b56-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3a2775d6-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3a279ef8-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3a27c806-7972-11ec-93d9-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:3a27f1dc-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:3a281acc-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3a2843d0-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3a286cd4-7972-11ec-93d9-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:3a28963c-7972-11ec-93d9-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:3a28bf36-7972-11ec-93d9-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3a28e844-7972-11ec-93d9-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:3a291526-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3a291526-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3a295270-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:3a295270-7972-11ec-93d9-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:3a298d4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a298d4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a298d4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a298d4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a29dc72-7972-11ec-93d9-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:3a2a10e8-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a2a10e8-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a2a10e8-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a2a10e8-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a2a6278-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:3a2a6278-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:3a2a9f36-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3a2a9f36-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3a2a9f36-7972-11ec-93d9-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3a2ae036-7972-11ec-93d9-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:3a2b0a3e-7972-11ec-93d9-0242ac110002 UniProtKB:P30988 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Calcitonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:3a2b372a-7972-11ec-93d9-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3a2b372a-7972-11ec-93d9-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3a2b7028-7972-11ec-93d9-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.082']} DrugCentral uuid:3a2b7028-7972-11ec-93d9-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.082']} DrugCentral uuid:3a2ba9a8-7972-11ec-93d9-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.706']} DrugCentral uuid:3a2ba9a8-7972-11ec-93d9-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.706']} DrugCentral uuid:3a2bded2-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone sodium phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3a2c04ca-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.179']} DrugCentral uuid:3a2c2df6-7972-11ec-93d9-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Cytosolic other (Annexin A1) DrugCentral uuid:3a2c534e-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3a2c7c48-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.599']} DrugCentral uuid:3a2ca560-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3a2ccefa-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.818']} DrugCentral uuid:3a2cfbbe-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:3a2d24ae-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3a2d4e52-7972-11ec-93d9-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3a2d77c4-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone cypionate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:3a2d9c86-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone succinate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3a2dc13e-7972-11ec-93d9-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:4456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone succinate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3a2dea56-7972-11ec-93d9-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:3a2e0f7c-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3a2e389e-7972-11ec-93d9-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:3a2e61ac-7972-11ec-93d9-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3a2e8aa6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:4466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eosin targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3a2eb576-7972-11ec-93d9-0242ac110002 UniProtKB:Q5VLE3 biolink:molecularly_interacts_with DrugCentral:4466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eosin targets Enzyme (RmtA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:3a2ef7ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:3a2ef7ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:3a2ef7ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:3a2ef7ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:3a2ef7ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:3a2ef7ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:3a2ef7ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:3a2f69ee-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosaprepitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:3a2f92fc-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trisodium citrate dihydrate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3a2fbc00-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trisodium citrate dihydrate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:3a2fe554-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium citrate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3a300e80-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium citrate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:3a303784-7972-11ec-93d9-0242ac110002 UniProtKB:P19111 biolink:molecularly_interacts_with DrugCentral:4480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium phosphate, monobasic targets Enzyme (Intestinal alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3a306088-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3a30944a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:3a30944a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:3a30944a-7972-11ec-93d9-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:3a30dd2e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3a30dd2e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3a30dd2e-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3a3127ca-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:3a3127ca-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:3a3127ca-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:3a316168-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3a318a58-7972-11ec-93d9-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3a31b3b6-7972-11ec-93d9-0242ac110002 UniProtKB:P28062 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3a31dcb0-7972-11ec-93d9-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:3a3205c8-7972-11ec-93d9-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:3a322ecc-7972-11ec-93d9-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3a325992-7972-11ec-93d9-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:3a3282dc-7972-11ec-93d9-0242ac110002 UniProtKB:P28065 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3a32abd6-7972-11ec-93d9-0242ac110002 UniProtKB:P40306 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3a32d4d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3a32fef6-7972-11ec-93d9-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:3a3327d2-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:3a3350c2-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:3a3379da-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:3a33a360-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3a33cc6e-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:3a33f586-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4485 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflorasone diacetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.536']} DrugCentral uuid:3a341f8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4485 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflorasone diacetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3a344a72-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclometasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3a346f3e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate is inverse agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:3a349842-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:3a34c1b4-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:3a34eac2-7972-11ec-93d9-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3a3513e4-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol acetate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:3a353892-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3a35620e-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:3a3586ee-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate is antagonist of GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:3a35ab9c-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.921']} DrugCentral uuid:3a35d4a0-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:3a35ff52-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.497']} DrugCentral uuid:3a36286a-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:3a364d0e-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Enzyme (Cytochrome P450 1A2) DrugCentral uuid:3a3672de-7972-11ec-93d9-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:3a369804-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3a36c126-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4504 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone valerate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3a36e5fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:3a370f28-7972-11ec-93d9-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3a37389a-7972-11ec-93d9-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3a37619e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3a378aa2-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.135']} DrugCentral uuid:3a37b39c-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:3a37de9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.917']} DrugCentral uuid:3a3807ac-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:3a3831a0-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:3a385ab8-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3a3888b2-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:3a3888b2-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:3a38b814-7972-11ec-93d9-0242ac110002 UniProtKB:P29218 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Enzyme (Inositol-1(or 4)-monophosphatase 1) DrugCentral uuid:3a38dcd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3a39063e-7972-11ec-93d9-0242ac110002 UniProtKB:P49190 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3a392f38-7972-11ec-93d9-0242ac110002 UniProtKB:P70555 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3a39581e-7972-11ec-93d9-0242ac110002 UniProtKB:P25961 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a39810e-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracosactide targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.19']} DrugCentral uuid:3a39abca-7972-11ec-93d9-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracosactide is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.268']} DrugCentral uuid:3a39d532-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:3a39f9e0-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3a3a22ee-7972-11ec-93d9-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:3a3a480a-7972-11ec-93d9-0242ac110002 UniProtKB:Q92953 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine is blocker of Ion channel (Potassium voltage-gated channel subfamily B member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3a3a710e-7972-11ec-93d9-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:3a3aa1ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3a3aa1ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3a3aa1ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3a3ae396-7972-11ec-93d9-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:3a3b0ca4-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbendazole targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.496']} DrugCentral uuid:3a3b359e-7972-11ec-93d9-0242ac110002 UniProtKB:P10424 biolink:molecularly_interacts_with DrugCentral:4536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbendazole targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:3a3b5eac-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.12']} DrugCentral uuid:3a3b8918-7972-11ec-93d9-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:3a3bb21c-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3a3bdc10-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:3a3c0640-7972-11ec-93d9-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3a3c2fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3a3c58ac-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3a3c81c4-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:3a3caab4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3a3cd430-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:3a3d08c4-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3a3d08c4-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3a3d08c4-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3a3d08c4-7972-11ec-93d9-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3a3d6120-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3a3d6120-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3a3d6120-7972-11ec-93d9-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3a3da61c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate is agonist of GPCR (GABA-B receptor) DrugCentral uuid:3a3da61c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate is agonist of GPCR (GABA-B receptor) DrugCentral uuid:3a3dd538-7972-11ec-93d9-0242ac110002 UniProtKB:Q6RY99 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate targets Unclassified (Gamma-hydroxybutyrate receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3a3dfe82-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochloric acid targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:3a3e27ae-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone probutate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3a3e4cd4-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3a3e760a-7972-11ec-93d9-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3a3e9f68-7972-11ec-93d9-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3a3ec876-7972-11ec-93d9-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:3a3efce2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a3efce2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a3efce2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a3efce2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a3f4cd8-7972-11ec-93d9-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3a3f75dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3a3f9ef4-7972-11ec-93d9-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3a3fc866-7972-11ec-93d9-0242ac110002 UniProtKB:O88944 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is inhibitor of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3a3ff16a-7972-11ec-93d9-0242ac110002 UniProtKB:P97414 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is inhibitor of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:3a401a64-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3a40434a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3a406c9e-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:3a409598-7972-11ec-93d9-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:3a40be92-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFU5 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Kinase (Inositol polyphosphate multikinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3a40e7a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHH9 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Kinase (Inositol hexakisphosphate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3a41114e-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tonzonium targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:3a413b6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:4605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tonzonium targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:3a416478-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clocortolone pivalate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3a418930-7972-11ec-93d9-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:4608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trypan blue targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3a41b298-7972-11ec-93d9-0242ac110002 UniProtKB:P25044 biolink:molecularly_interacts_with DrugCentral:4608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trypan blue targets Enzyme (Tyrosine-protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3a41dbba-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone enantate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:3a42009a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3a4229b2-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3a42536a-7972-11ec-93d9-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.1']} DrugCentral uuid:3a427c8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3a42a59a-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3a42d038-7972-11ec-93d9-0242ac110002 UniProtKB:P27471 biolink:molecularly_interacts_with DrugCentral:4615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 N-Acetylglucosamine targets Unclassified (Killer cell lectin-like receptor subfamily B member 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3a42fa72-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:3a43239e-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3a434cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:3a4376be-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3a439fe0-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3a43c998-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3a43f2ce-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:3a441c9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.1']} DrugCentral uuid:3a4445bc-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3a446ee8-7972-11ec-93d9-0242ac110002 UniProtKB:P05413 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Cytosolic other (Fatty acid-binding protein, heart) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.56']} DrugCentral uuid:3a4497ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3a44c262-7972-11ec-93d9-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3a44eb5c-7972-11ec-93d9-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3a45146a-7972-11ec-93d9-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:3a453df0-7972-11ec-93d9-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:3a456712-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3a459048-7972-11ec-93d9-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:3a45b960-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3a45e2d2-7972-11ec-93d9-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:4621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomefolic acid targets Enzyme (Thymidylate synthase) DrugCentral uuid:3a460794-7972-11ec-93d9-0242ac110002 UniProtKB:P23897 biolink:molecularly_interacts_with DrugCentral:4622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linaclotide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:3a4630de-7972-11ec-93d9-0242ac110002 UniProtKB:P25092 biolink:molecularly_interacts_with DrugCentral:4622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linaclotide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.907']} DrugCentral uuid:3a466d38-7972-11ec-93d9-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:3a466d38-7972-11ec-93d9-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:3a466d38-7972-11ec-93d9-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:3a466d38-7972-11ec-93d9-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:3a466d38-7972-11ec-93d9-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:3a466d38-7972-11ec-93d9-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:3a46cae4-7972-11ec-93d9-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:4624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylacetic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:3a46f3fc-7972-11ec-93d9-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:3a471d82-7972-11ec-93d9-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:3a474686-7972-11ec-93d9-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:3a476fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:3a4798d4-7972-11ec-93d9-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3a47c282-7972-11ec-93d9-0242ac110002 UniProtKB:Q63931 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:3a47ef96-7972-11ec-93d9-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3a47ef96-7972-11ec-93d9-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3a4824e8-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4628 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enzalutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.31']} DrugCentral uuid:3a484f54-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4628 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enzalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:3a487bb4-7972-11ec-93d9-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:4630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium pyrophosphate targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:3a48a6a2-7972-11ec-93d9-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:3a48d6cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3a48d6cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3a48d6cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3a48d6cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:3a491b96-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trabectedin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3a494486-7972-11ec-93d9-0242ac110002 UniProtKB:O54915 biolink:molecularly_interacts_with DrugCentral:4633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trabectedin is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3a496e48-7972-11ec-93d9-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide is inhibitor of Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3a499800-7972-11ec-93d9-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3a49c118-7972-11ec-93d9-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3a49ea30-7972-11ec-93d9-0242ac110002 UniProtKB:O35435 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:3a4a1352-7972-11ec-93d9-0242ac110002 UniProtKB:Q54A96 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:3a4a3d5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:4635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Choline C-11 targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3a4a674e-7972-11ec-93d9-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3a4a903e-7972-11ec-93d9-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:3a4ab99c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99895 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Chymotrypsin C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3a4ae28c-7972-11ec-93d9-0242ac110002 UniProtKB:P16278 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:3a4b0b90-7972-11ec-93d9-0242ac110002 UniProtKB:O06446 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Unclassified (Protein translocase subunit SecA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3a4b349e-7972-11ec-93d9-0242ac110002 UniProtKB:Q2FUW6 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Unclassified (Protein translocase subunit SecA 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3a4b5e4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3a4b8746-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:3a4bb040-7972-11ec-93d9-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3a4bd958-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3a4c03a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3a4c2dfe-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3a4c5720-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3a4c802e-7972-11ec-93d9-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3a4ca9a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid is agonist of GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3a4cd2cc-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:3a4cfbe4-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3a4d24fc-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:3a4d4ebe-7972-11ec-93d9-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:3a4d77a4-7972-11ec-93d9-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3a4da076-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4dcab0-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:3a4df6ac-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4e200a-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:3a4e4a6c-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:3a4e73ac-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4e9cb0-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3a4ec5aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4eee9a-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4f1852-7972-11ec-93d9-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3a4f414c-7972-11ec-93d9-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4f6a32-7972-11ec-93d9-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4f932c-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4fbd5c-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a4fe64c-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a500f3c-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a5038a4-7972-11ec-93d9-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a5061a8-7972-11ec-93d9-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a508ab6-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:3a50b388-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a50dd0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:4655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedisamil is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:3a510630-7972-11ec-93d9-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metamizole is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.041']} DrugCentral uuid:3a512f2a-7972-11ec-93d9-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:3a515838-7972-11ec-93d9-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3a5181dc-7972-11ec-93d9-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.59']} DrugCentral uuid:3a51aacc-7972-11ec-93d9-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:3a51d3bc-7972-11ec-93d9-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:4663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoin targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3a51fcd4-7972-11ec-93d9-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:4663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoin targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:3a52281c-7972-11ec-93d9-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:3a52513e-7972-11ec-93d9-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3a527a6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3a52a364-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.932']} DrugCentral uuid:3a52cd44-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.776']} DrugCentral uuid:3a52f652-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:3a531f6a-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.779']} DrugCentral uuid:3a534972-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.248']} DrugCentral uuid:3a537294-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.428']} DrugCentral uuid:3a539bac-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:3a53c55a-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:3a53eeb8-7972-11ec-93d9-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:3a5417bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:3a5440d4-7972-11ec-93d9-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3a5469f6-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.14']} DrugCentral uuid:3a549386-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:3a54bc80-7972-11ec-93d9-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:3a54e570-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:3a550e74-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:3a55398a-7972-11ec-93d9-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:3a5562ac-7972-11ec-93d9-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:3a558bc4-7972-11ec-93d9-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3a55b54a-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:3a55de58-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:3a560784-7972-11ec-93d9-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3a56316e-7972-11ec-93d9-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:3a565b08-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:3a5683e4-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:3a56ace8-7972-11ec-93d9-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3a56d60a-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:3a57015c-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obidoxime targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.67']} DrugCentral uuid:3a572a92-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3a575396-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3a577c90-7972-11ec-93d9-0242ac110002 UniProtKB:A5H660 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Unclassified (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:3a57a616-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:3a57cf42-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:3a57f86e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3a5822da-7972-11ec-93d9-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3a584cd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:3a58762c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:3a589f62-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3a58c9f6-7972-11ec-93d9-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:3a58f35e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:3a591c9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:3a594674-7972-11ec-93d9-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:3a597004-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:3a5998f4-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3a59c202-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3a59eae8-7972-11ec-93d9-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3a5a148c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3a5a3e62-7972-11ec-93d9-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:3a5a6752-7972-11ec-93d9-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a5a9038-7972-11ec-93d9-0242ac110002 UniProtKB:O35678 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a5abc02-7972-11ec-93d9-0242ac110002 UniProtKB:O08914 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:3a5af0be-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:3a5af0be-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:3a5af0be-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:3a5af0be-7972-11ec-93d9-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:3a5b3e66-7972-11ec-93d9-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3a5b672e-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3a5b9014-7972-11ec-93d9-0242ac110002 UniProtKB:Q7T664 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:3a5bb922-7972-11ec-93d9-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:4696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remikiren is inhibitor of Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:3a5be2c6-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3a5c0bde-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:3a5c3500-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:3a5c5dfa-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:3a5c8974-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.93']} DrugCentral uuid:3a5cb296-7972-11ec-93d9-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:3a5cdbae-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 semustine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.744']} DrugCentral uuid:3a5d04bc-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.074']} DrugCentral uuid:3a5d2e24-7972-11ec-93d9-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:3a5d52b4-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.624']} DrugCentral uuid:3a5d7bae-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:3a5da548-7972-11ec-93d9-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:3a5dcf82-7972-11ec-93d9-0242ac110002 UniProtKB:P32241 biolink:molecularly_interacts_with DrugCentral:4710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatorelin is agonist of GPCR (Vasoactive intestinal polypeptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3a5df98a-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:3a5e228e-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3a5e4c8c-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:3a5e7590-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3a5e9ea8-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3a5ec7ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a5ef150-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3a5f1b08-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:3a5f4416-7972-11ec-93d9-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3a5f6d38-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:3a5f96fa-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3a5fc008-7972-11ec-93d9-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3a5fe920-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3a60124c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3a603c90-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3a60658a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3a608eac-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3a60b828-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3a60e136-7972-11ec-93d9-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a610a4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:3a61335c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3a615d28-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:3a61865e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3a61af94-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3a61d8b6-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:3a620458-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a622d7a-7972-11ec-93d9-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3a625688-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3a627faa-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3a62a930-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3a62d248-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3a62fb6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q62137 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3a63252c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:3a634e58-7972-11ec-93d9-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:3a637766-7972-11ec-93d9-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3a63a47a-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:3a63a47a-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:3a63e41c-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3a63e41c-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3a63e41c-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3a642986-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3a642986-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3a645f6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q63272 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3a648c64-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.391']} DrugCentral uuid:3a648c64-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.391']} DrugCentral uuid:3a64c5ee-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:3a64c5ee-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:3a64fbc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.907']} DrugCentral uuid:3a6524bc-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:3a654dd4-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3a6577b4-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3a65a1d0-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3a65cade-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:3a65f3f6-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3a661cfa-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:3a66466c-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3a666f7a-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.337']} DrugCentral uuid:3a6698a6-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.947']} DrugCentral uuid:3a66c1aa-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:3a66eb6c-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.456']} DrugCentral uuid:3a67148e-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.845']} DrugCentral uuid:3a673dba-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.886']} DrugCentral uuid:3a676754-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:3a6793d2-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.432']} DrugCentral uuid:3a67bf7e-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.903']} DrugCentral uuid:3a67e896-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Breakpoint cluster region protein) DrugCentral uuid:3a680db2-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3a6836ac-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3a685fba-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:3a6888dc-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:3a68b280-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:3a68db8e-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:3a6904b0-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.268']} DrugCentral uuid:3a692dd2-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:3a695a32-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.658']} DrugCentral uuid:3a69832c-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:3a69ac30-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:3a69d552-7972-11ec-93d9-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:3a69fec4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3a6a27f0-7972-11ec-93d9-0242ac110002 UniProtKB:P49336 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Cyclin-dependent kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.17']} DrugCentral uuid:3a6a511c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3a6a7ae8-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3a6aa7c0-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3a6aa7c0-7972-11ec-93d9-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3a6adcf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3a6b06b6-7972-11ec-93d9-0242ac110002 UniProtKB:O95838 biolink:molecularly_interacts_with DrugCentral:4718 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teduglutide is agonist of GPCR (Glucagon-like peptide 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:3a6b31a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z0W0 biolink:molecularly_interacts_with DrugCentral:4718 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teduglutide targets GPCR (Glucagon-like peptide 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.1']} DrugCentral uuid:3a6b5aa8-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:3a6b7f60-7972-11ec-93d9-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:3a6ba40e-7972-11ec-93d9-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:3a6bc93e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:3a6bedf6-7972-11ec-93d9-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:3a6c12cc-7972-11ec-93d9-0242ac110002 UniProtKB:P55157 biolink:molecularly_interacts_with DrugCentral:4721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomitapide is inhibitor of Cytosolic other (Microsomal triglyceride transfer protein large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:3a6c3bee-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:4723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinimide targets Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.58']} DrugCentral uuid:3a6c65ce-7972-11ec-93d9-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinimide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3a6c8edc-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:4727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.5']} DrugCentral uuid:3a6cb7f4-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.573']} DrugCentral uuid:3a6ce10c-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:3a6d0dd0-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:3a6d36e8-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3a6d60c8-7972-11ec-93d9-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3a6d8a26-7972-11ec-93d9-0242ac110002 UniProtKB:O97554 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3a6db334-7972-11ec-93d9-0242ac110002 UniProtKB:O02768 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:3a6de020-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3a6de020-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3a6e152c-7972-11ec-93d9-0242ac110002 UniProtKB:P48050 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap is activator of Ion channel (Inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6e77b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a6f671a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:3a6f671a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:3a6f671a-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:3a6fb134-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:3a6fb134-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:3a6fb134-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:3a6ffad6-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:3a6ffad6-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:3a6ffad6-7972-11ec-93d9-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:3a703be0-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3a7068e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3a7068e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3a709f5e-7972-11ec-93d9-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3a70c876-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:3a70f198-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.971']} DrugCentral uuid:3a711aa6-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.035']} DrugCentral uuid:3a714436-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:3a716e02-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.071']} DrugCentral uuid:3a719710-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:3a71c028-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.135']} DrugCentral uuid:3a71e9ea-7972-11ec-93d9-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:3a7212ee-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.718']} DrugCentral uuid:3a723c10-7972-11ec-93d9-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:3a726622-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3a729200-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3a72bb18-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3a72e552-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3a730ff0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a7338f4-7972-11ec-93d9-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a736216-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:3a738b38-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3a73b4fa-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.111']} DrugCentral uuid:3a73ddf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3a7406f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q932Y6 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:3a742fe8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3a747624-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:3a747624-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:3a747624-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:3a747624-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:3a747624-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:3a747624-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:3a747624-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:3a747624-7972-11ec-93d9-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:3a74e4ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q5TIX5 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Enzyme (ATP synthase subunit c) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3a750dbe-7972-11ec-93d9-0242ac110002 UniProtKB:P00845 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Enzyme (ATP synthase subunit c) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3a753708-7972-11ec-93d9-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:4744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crofelemer is inhibitor of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:3a75602a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5XXA6 biolink:molecularly_interacts_with DrugCentral:4744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crofelemer is inhibitor of Ion channel (Anoctamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:3a7589e2-7972-11ec-93d9-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3a75b2f0-7972-11ec-93d9-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3a75dc12-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.577']} DrugCentral uuid:3a76052a-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ospemifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.082']} DrugCentral uuid:3a763176-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobetaxolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3a765ad4-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobetaxolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:3a7683ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:4757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyl fumarate targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3a76ae3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14145 biolink:molecularly_interacts_with DrugCentral:4757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyl fumarate is inhibitor of Cytosolic other (Kelch-like ECH-associated protein 1) DrugCentral uuid:3a76d2f2-7972-11ec-93d9-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.658']} DrugCentral uuid:3a76fc82-7972-11ec-93d9-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3a77259a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3a774f3e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3a777856-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:3a77a150-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3a77ca68-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:3a77f42a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3a781e96-7972-11ec-93d9-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3a7847b8-7972-11ec-93d9-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3a7870da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3a789aba-7972-11ec-93d9-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:4778 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ridaforolimus is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:3a78c3a0-7972-11ec-93d9-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.289']} DrugCentral uuid:3a78ecae-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:3a7915c6-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.961']} DrugCentral uuid:3a793f7e-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.477']} DrugCentral uuid:3a79688c-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.111']} DrugCentral uuid:3a7991a4-7972-11ec-93d9-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:3a79bbca-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:3a79e848-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:3a7a1476-7972-11ec-93d9-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium propionate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.29']} DrugCentral uuid:3a7a3dac-7972-11ec-93d9-0242ac110002 UniProtKB:B2GV46 biolink:molecularly_interacts_with DrugCentral:4796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium propionate targets GPCR (Free fatty acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3a7a671e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['1.2']} DrugCentral uuid:3a7a9036-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.08']} DrugCentral uuid:3a7aba2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['1.9']} DrugCentral uuid:3a7ae324-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3a7b0cdc-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3a7b35d6-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3a7b5ebc-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3a7b87d4-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:3a7bb290-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3a7bdbb2-7972-11ec-93d9-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3a7c04c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:3a7c2e6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:3a7c5768-7972-11ec-93d9-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:3a7c80da-7972-11ec-93d9-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3a7ca9d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a7cd396-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3a7cfcae-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:3a7d25d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:3a7d4ede-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a7d78be-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:3a7da1c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:3a7dcad0-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.036']} DrugCentral uuid:3a7df3de-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:3a7e1e68-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4804 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palifermin is agonist of Kinase (Fibroblast growth factor receptor 2) DrugCentral uuid:3a7e430c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3a7e6c06-7972-11ec-93d9-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:3a7e9604-7972-11ec-93d9-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3a7ebfa8-7972-11ec-93d9-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:3a7ee88e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:3a7f11c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.131']} DrugCentral uuid:3a7f3c26-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:3a7f6570-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3a7f8ea6-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3a7fb796-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3a7fe112-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3a800a2a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3a803338-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3a805c28-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3a8085ea-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:3a80aee4-7972-11ec-93d9-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3a80d7de-7972-11ec-93d9-0242ac110002 UniProtKB:P35563 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3a8100e2-7972-11ec-93d9-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3a812be4-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:3a8154fc-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:3a817e1e-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3a81a79a-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:3a81d0da-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:3a81face-7972-11ec-93d9-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:3a822404-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.268']} DrugCentral uuid:3a824dbc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:4807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riociguat targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 7B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:3a8276d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riociguat is positive allosteric modulator of Enzyme (Guanylate cyclase soluble subunit beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'MEC', 'has_quantitative_value': ['7.523']} DrugCentral uuid:3a82a0c8-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3a82c9ae-7972-11ec-93d9-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3a82f41a-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:3a831d00-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.658']} DrugCentral uuid:3a8345fa-7972-11ec-93d9-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.569']} DrugCentral uuid:3a836f26-7972-11ec-93d9-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macitentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:3a8398ca-7972-11ec-93d9-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macitentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.408']} DrugCentral uuid:3a83c1c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3a83eb5e-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3a841462-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:3a843f1e-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:3a846890-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:3a84918a-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3a84bba6-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3a84e4b4-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3a850df4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:3a853720-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRX8 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Unclassified (Redox-regulatory protein FAM213A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3a856088-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:3a8589aa-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.495']} DrugCentral uuid:3a85b2c2-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.721']} DrugCentral uuid:3a85dbd0-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:3a860808-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.387']} DrugCentral uuid:3a8633dc-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:3a865cea-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.194']} DrugCentral uuid:3a8686c0-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:3a86b186-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:3a86da9e-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:3a8703ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3a872d0a-7972-11ec-93d9-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.155']} DrugCentral uuid:3a875622-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:3a877f30-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:3a87a83e-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.143']} DrugCentral uuid:3a87d23c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofosbuvir is inhibitor of Enzyme (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:3a87fb40-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofosbuvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC90', 'has_quantitative_value': ['6.959']} DrugCentral uuid:3a882444-7972-11ec-93d9-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3a8851b2-7972-11ec-93d9-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3a8851b2-7972-11ec-93d9-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3a88889e-7972-11ec-93d9-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:3a88b1c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6GYR8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Polyprotein (Polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:3a88daf6-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:3a890468-7972-11ec-93d9-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:4813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luliconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:3a89293e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:3a895260-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3a897baa-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:3a89a580-7972-11ec-93d9-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lixisenatide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.845']} DrugCentral uuid:3a89ce84-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:3a89f7b0-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:3a8a2226-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.796']} DrugCentral uuid:3a8a4d6e-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.824']} DrugCentral uuid:3a8a769a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.222']} DrugCentral uuid:3a8aa0ac-7972-11ec-93d9-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a8ac9ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3a8af3f4-7972-11ec-93d9-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3a8b1d98-7972-11ec-93d9-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3a8b46b0-7972-11ec-93d9-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Enzyme (DNA-directed RNA polymerase subunit beta) DrugCentral uuid:3a8b6bb8-7972-11ec-93d9-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 florbetaben F18 targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:3a8b94f8-7972-11ec-93d9-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:4820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasimelteon is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.45']} DrugCentral uuid:3a8bbe1a-7972-11ec-93d9-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:4820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasimelteon is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:3a8be750-7972-11ec-93d9-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 seractide is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.009']} DrugCentral uuid:3a8c111c-7972-11ec-93d9-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:4822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laninamivir octanoate hydrate targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:3a8c3a20-7972-11ec-93d9-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:4822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laninamivir octanoate hydrate targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3a8c6342-7972-11ec-93d9-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:3a8c8c3c-7972-11ec-93d9-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:3a8cb5ea-7972-11ec-93d9-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3a8cdee4-7972-11ec-93d9-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3a8d07f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y3R4 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Sialidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:3a8d311e-7972-11ec-93d9-0242ac110002 UniProtKB:D5F1R0 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3a8d5aa4-7972-11ec-93d9-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3a8d83c6-7972-11ec-93d9-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:3a8dace8-7972-11ec-93d9-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3a8dd614-7972-11ec-93d9-0242ac110002 UniProtKB:Q9IGQ6 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:3a8e004e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilefrine pivalate is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:3a8e251a-7972-11ec-93d9-0242ac110002 UniProtKB:P48357 biolink:molecularly_interacts_with DrugCentral:4826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metreleptin is agonist of Membrane receptor (Leptin receptor) DrugCentral uuid:3a8e49dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:3a8e72e0-7972-11ec-93d9-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3a8e9cc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q08493 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:3a8ec6b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.131']} DrugCentral uuid:3a8eefb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M3M2 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.959']} DrugCentral uuid:3a8f192a-7972-11ec-93d9-0242ac110002 UniProtKB:A0PJK1 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:3a8f4224-7972-11ec-93d9-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.081']} DrugCentral uuid:3a8f6b1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WWX8 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/myo-inositol cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:3a8f94c2-7972-11ec-93d9-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.244']} DrugCentral uuid:3a8fbee8-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxegol is antagonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:3a8fe3b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemigliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.328']} DrugCentral uuid:3a900de4-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemigliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:3a903706-7972-11ec-93d9-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:4834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eliglustat is inhibitor of Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.827']} DrugCentral uuid:3a9060a0-7972-11ec-93d9-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3a9089c2-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3a90b2d0-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3a90dbfc-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:3a91058c-7972-11ec-93d9-0242ac110002 UniProtKB:P33033 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:3a912e90-7972-11ec-93d9-0242ac110002 UniProtKB:P41149 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:3a915794-7972-11ec-93d9-0242ac110002 UniProtKB:P56450 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:3a91808e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01727 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:3a91ace4-7972-11ec-93d9-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:3a91d5fc-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:4839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprotinin is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3a91fef6-7972-11ec-93d9-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:4839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprotinin is inhibitor of Enzyme (Plasma kallikrein) DrugCentral uuid:3a92248a-7972-11ec-93d9-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:4846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ecallantide is inhibitor of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.602']} DrugCentral uuid:3a924dd4-7972-11ec-93d9-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:4848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatropin is agonist of GPCR (Growth hormone receptor) DrugCentral uuid:3a927282-7972-11ec-93d9-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:4853 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cridanimod targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3a929b68-7972-11ec-93d9-0242ac110002 UniProtKB:Q3TBT3 biolink:molecularly_interacts_with DrugCentral:4853 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cridanimod targets Unclassified (Stimulator of interferon genes protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3a92c50c-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conjugated estrogens is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:3a92eac8-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conjugated estrogens is agonist of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:3a930f6c-7972-11ec-93d9-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:3a933884-7972-11ec-93d9-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:3a9362dc-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:3a9387f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate is agonist of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:3a93acce-7972-11ec-93d9-0242ac110002 UniProtKB:Q60748 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3a93d5d2-7972-11ec-93d9-0242ac110002 UniProtKB:P47866 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3a93ff80-7972-11ec-93d9-0242ac110002 UniProtKB:Q13324 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3a9428b6-7972-11ec-93d9-0242ac110002 UniProtKB:P34998 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.481']} DrugCentral uuid:3a9455c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenibut is agonist of GPCR (GABA-B receptor) DrugCentral uuid:3a9455c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenibut is agonist of GPCR (GABA-B receptor) DrugCentral uuid:3a9484e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3a94ae58-7972-11ec-93d9-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:3a94eeb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a94eeb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a94eeb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a94eeb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a94eeb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a94eeb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a94eeb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3a956442-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.951']} DrugCentral uuid:3a958d50-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.035']} DrugCentral uuid:3a95b67c-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebanazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:3a95dbde-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebanazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:3a9600a0-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3a9629a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3a96538e-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:3a967ce2-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3a96a5e6-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3a96cee0-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3a96f802-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3a9722e6-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3a974bf4-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3a9774ee-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3a979e74-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3a97c78c-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:3a97f0b8-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3a9819c6-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3a984324-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3a986c32-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:3a98952c-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3a98be3a-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3a98e888-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3a991196-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:3a993aa4-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3a9963c6-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3a998d56-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:3a99b650-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:3a99df5e-7972-11ec-93d9-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:3a9a0876-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3a9a31f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3a9a5c18-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3a9a851c-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3a9aaf24-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3a9ad88c-7972-11ec-93d9-0242ac110002 UniProtKB:P41212 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transcription factor (Transcription factor ETV6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3a9b0190-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:3a9b2b20-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:3a9b55c8-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.155']} DrugCentral uuid:3a9b7efe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:3a9ba802-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:3a9bd124-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3a9bfaa0-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3a9c23c2-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3a9c4cee-7972-11ec-93d9-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3a9c7624-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3a9ca112-7972-11ec-93d9-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:3a9cca34-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:3a9cf338-7972-11ec-93d9-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:3a9d1cc8-7972-11ec-93d9-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3a9d4608-7972-11ec-93d9-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3a9d72f4-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:3a9d72f4-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:3a9da242-7972-11ec-93d9-0242ac110002 UniProtKB:P25116 biolink:molecularly_interacts_with DrugCentral:4870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorapaxar is antagonist of GPCR (Proteinase-activated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.092']} DrugCentral uuid:3a9dcbc8-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedizolid phosphate targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3a9df4d6-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedizolid phosphate targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3a9e1de4-7972-11ec-93d9-0242ac110002 UniProtKB:F2SHH3 biolink:molecularly_interacts_with DrugCentral:4874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efinaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:3a9e43a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:3a9e6df8-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.64']} DrugCentral uuid:3a9e971a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.64']} DrugCentral uuid:3a9ec028-7972-11ec-93d9-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.046']} DrugCentral uuid:3a9ee940-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.301']} DrugCentral uuid:3a9f1316-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3a9f3c4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3a9f655a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3a9f8eea-7972-11ec-93d9-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3a9fb82a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3a9fe1e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3aa00b0e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3aa03502-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:3aa05e38-7972-11ec-93d9-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:3aa0876e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.67']} DrugCentral uuid:3aa0b068-7972-11ec-93d9-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:3aa0da16-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:3aa1031a-7972-11ec-93d9-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.569']} DrugCentral uuid:3aa12d5e-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3aa15694-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3aa1802e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:3aa1a950-7972-11ec-93d9-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:3aa1d25e-7972-11ec-93d9-0242ac110002 UniProtKB:P26637 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Leucine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:3aa1fb80-7972-11ec-93d9-0242ac110002 UniProtKB:F2SF18 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole is inhibitor of Enzyme (Leucine-tRNA ligase) DrugCentral uuid:3aa22394-7972-11ec-93d9-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3aa24e3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NEB9 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 3-kinase catalytic subunit type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3aa2775e-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.086']} DrugCentral uuid:3aa2a134-7972-11ec-93d9-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.248']} DrugCentral uuid:3aa2ca4c-7972-11ec-93d9-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.051']} DrugCentral uuid:3aa2f36e-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.602']} DrugCentral uuid:3aa31c90-7972-11ec-93d9-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:4879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxaparin sodium is activator of Secreted (Antithrombin-III) DrugCentral uuid:3aa341c0-7972-11ec-93d9-0242ac110002 UniProtKB:P58308 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant targets GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:3aa36af6-7972-11ec-93d9-0242ac110002 UniProtKB:P58307 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant targets GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:3aa39422-7972-11ec-93d9-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant is antagonist of GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:3aa3bd44-7972-11ec-93d9-0242ac110002 UniProtKB:O43614 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant is antagonist of GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:3aa3e756-7972-11ec-93d9-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3aa4106e-7972-11ec-93d9-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3aa43990-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:3aa462b2-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:3aa48cc4-7972-11ec-93d9-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3aa4b5e6-7972-11ec-93d9-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3aa4df08-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:3aa50834-7972-11ec-93d9-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:3aa53228-7972-11ec-93d9-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dulaglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) DrugCentral uuid:3aa55708-7972-11ec-93d9-0242ac110002 UniProtKB:P16233 biolink:molecularly_interacts_with DrugCentral:4886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetilistat is inhibitor of Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.225']} DrugCentral uuid:3aa58016-7972-11ec-93d9-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:4888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiroxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:3aa5aa00-7972-11ec-93d9-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:4888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiroxostat is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.276']} DrugCentral uuid:3aa5d58e-7972-11ec-93d9-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:4889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asunaprevir targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:3aa5fe7e-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asunaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:3aa627aa-7972-11ec-93d9-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3aa65234-7972-11ec-93d9-0242ac110002 UniProtKB:Q8C3K6 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:3aa67b38-7972-11ec-93d9-0242ac110002 UniProtKB:P53790 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:3aa6a450-7972-11ec-93d9-0242ac110002 UniProtKB:Q923I7 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:3aa6cd54-7972-11ec-93d9-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.727']} DrugCentral uuid:3aa6f70c-7972-11ec-93d9-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.132']} DrugCentral uuid:3aa72132-7972-11ec-93d9-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luseogliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.399']} DrugCentral uuid:3aa74a4a-7972-11ec-93d9-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luseogliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.646']} DrugCentral uuid:3aa7734e-7972-11ec-93d9-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4892 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofogliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.073']} DrugCentral uuid:3aa79fcc-7972-11ec-93d9-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4892 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofogliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.538']} DrugCentral uuid:3aa7c93e-7972-11ec-93d9-0242ac110002 UniProtKB:P07650 biolink:molecularly_interacts_with DrugCentral:4893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipiracil targets Enzyme (Thymidine phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3aa7f26a-7972-11ec-93d9-0242ac110002 UniProtKB:P19971 biolink:molecularly_interacts_with DrugCentral:4893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipiracil is inhibitor of Enzyme (Thymidine phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:3aa81bd2-7972-11ec-93d9-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:4894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iguratimod targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3aa844d6-7972-11ec-93d9-0242ac110002 UniProtKB:P14740 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.54']} DrugCentral uuid:3aa86dda-7972-11ec-93d9-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.585']} DrugCentral uuid:3aa896ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.268']} DrugCentral uuid:3aa8c082-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.432']} DrugCentral uuid:3aa8e986-7972-11ec-93d9-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:3aa9128a-7972-11ec-93d9-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.167']} DrugCentral uuid:3aa93b8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:3aa96690-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3aa99016-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edoxaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.252']} DrugCentral uuid:3aa9b96a-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4898 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netupitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.022']} DrugCentral uuid:3aa9e296-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:3aaa0bfe-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:3aaa3516-7972-11ec-93d9-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:3aaa5f1e-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.509']} DrugCentral uuid:3aaa882c-7972-11ec-93d9-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:4900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diquafosol is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3aaab1d0-7972-11ec-93d9-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:4900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diquafosol is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.469']} DrugCentral uuid:3aaadaf2-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin glargine is agonist of Kinase (Insulin receptor) DrugCentral uuid:3aaaffb4-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidafenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['8.384']} DrugCentral uuid:3aab29a8-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidafenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['9.499']} DrugCentral uuid:3aab52c0-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:3aab7bce-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:3aaba4dc-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:3aabce58-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3aabf752-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:3aac2060-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:3aac4950-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3aac72ae-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.21']} DrugCentral uuid:3aac9be4-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3aacc4d4-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3aacede2-7972-11ec-93d9-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3aad1ae2-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.38']} DrugCentral uuid:3aad43fa-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.02']} DrugCentral uuid:3aad6d12-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3aad9634-7972-11ec-93d9-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:3aadbfec-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3aade8fa-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3aae11fe-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3aae3b7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3aae65aa-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:3aae8ec2-7972-11ec-93d9-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3aaeb7da-7972-11ec-93d9-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3aaee2f0-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3aaf0ea6-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3aaf37be-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3aaf614e-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3aaf8b1a-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:3aafb432-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3aafdd4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3ab0064e-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:3ab02fde-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3ab058f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3ab081fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3ab0ac52-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3ab0d772-7972-11ec-93d9-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3ab1008a-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3ab129a2-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3ab15364-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3ab17c86-7972-11ec-93d9-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3ab1a59e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3ab1ceb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3ab1f828-7972-11ec-93d9-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3ab2212c-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3ab24a44-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:3ab2744c-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3ab29f80-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3ab2c88e-7972-11ec-93d9-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3ab2f1a6-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3ab31b54-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3ab345ac-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3ab36ece-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:3ab39804-7972-11ec-93d9-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3ab3c16c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3ab3ea70-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3ab41360-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3ab43c6e-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3ab466a8-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3ab48fa2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:3ab4b8a6-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3ab4e1b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.66']} DrugCentral uuid:3ab50b58-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3ab53470-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:3ab55d74-7972-11ec-93d9-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3ab586c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3ab5afea-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:3ab5d8ee-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:3ab601f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3ab62c54-7972-11ec-93d9-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3ab65918-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3ab68320-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3ab6ac38-7972-11ec-93d9-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3ab6d5f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.29']} DrugCentral uuid:3ab6ff30-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3ab7283e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3ab75156-7972-11ec-93d9-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3ab77adc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3ab7a3d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3ab7cce4-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3ab7f5f2-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3ab8200e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3ab8491c-7972-11ec-93d9-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3ab87220-7972-11ec-93d9-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3ab89be2-7972-11ec-93d9-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3ab8c4fa-7972-11ec-93d9-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3ab8ee08-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:3ab9170c-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:3ab941b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3ab96ac2-7972-11ec-93d9-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3ab993d0-7972-11ec-93d9-0242ac110002 UniProtKB:P49840 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Glycogen synthase kinase-3 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3ab9bcde-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:3ab9e8c6-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3aba1210-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3aba3b0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3aba640e-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3aba8ee8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3abab800-7972-11ec-93d9-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3abae10e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3abb0a8a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3abb338e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3abb5ca6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3abb85aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3abbafc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3abbd8ca-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:3abc01d8-7972-11ec-93d9-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3abc2adc-7972-11ec-93d9-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3abc5480-7972-11ec-93d9-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3abc7d70-7972-11ec-93d9-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:3abca67e-7972-11ec-93d9-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3abccf78-7972-11ec-93d9-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:3abcf930-7972-11ec-93d9-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3abd22d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:3abd4bd8-7972-11ec-93d9-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3abd74e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:3abd9ef8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:3abdc7fc-7972-11ec-93d9-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3abdf128-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3abe1a90-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:3abe43a8-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3abe6cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3abe96be-7972-11ec-93d9-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3abec076-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3abee98e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3abf127e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:3abf3b8c-7972-11ec-93d9-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3abf67ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3abf90fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:3abfb9f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3abfe320-7972-11ec-93d9-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3ac00c92-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3ac0358c-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3ac05e86-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3ac08848-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:3ac0b156-7972-11ec-93d9-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3ac0da5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3ac10368-7972-11ec-93d9-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:3ac12e06-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:3ac15930-7972-11ec-93d9-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3ac18234-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3ac1ab38-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3ac1d4b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:3ac1fdc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3ac226c6-7972-11ec-93d9-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3ac24fc0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3ac27a68-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3ac2a36c-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3ac2ccca-7972-11ec-93d9-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:3ac2f6e6-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3ac32030-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3ac34934-7972-11ec-93d9-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3ac37256-7972-11ec-93d9-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3ac39bbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.07']} DrugCentral uuid:3ac3c4d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16566 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3ac3ee66-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3ac41774-7972-11ec-93d9-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3ac44122-7972-11ec-93d9-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:3ac46a3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3ac4935c-7972-11ec-93d9-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3ac4bc6a-7972-11ec-93d9-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:3ac4e726-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3ac5102a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3ac5394c-7972-11ec-93d9-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3ac56386-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3ac58ce4-7972-11ec-93d9-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3ac5b606-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3ac5df1e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3ac608d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:3ac631e4-7972-11ec-93d9-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3ac65af2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3ac68504-7972-11ec-93d9-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3ac6b01a-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3ac6d964-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3ac7025e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3ac72b8a-7972-11ec-93d9-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3ac754f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3ac77e0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:3ac7a722-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3ac7d030-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:3ac7f9e8-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3ac822ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3ac84c0e-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3ac87634-7972-11ec-93d9-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3ac89f6a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3ac8c86e-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3ac8f186-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3ac91aee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3ac943f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3ac96cec-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3ac995fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3ac9bfa8-7972-11ec-93d9-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:3ac9e8c0-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3aca11ba-7972-11ec-93d9-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3aca3abe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:3aca65a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:3aca8fc8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3acab962-7972-11ec-93d9-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3acae27a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3acb0bc4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3acb34c8-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:3acb5dc2-7972-11ec-93d9-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3acb88a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3acbb1be-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3acbdad6-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.28']} DrugCentral uuid:3acc03d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3acc2ef0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3acc5a4c-7972-11ec-93d9-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:3acc835a-7972-11ec-93d9-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3accac68-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:3accd5ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3accff06-7972-11ec-93d9-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:3acd2814-7972-11ec-93d9-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3acd5122-7972-11ec-93d9-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3acd7b02-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3acda424-7972-11ec-93d9-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3acdcd32-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:3acdf79e-7972-11ec-93d9-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3ace20d4-7972-11ec-93d9-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:3ace49d8-7972-11ec-93d9-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:3ace73c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3ace9d52-7972-11ec-93d9-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:3acec660-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.983']} DrugCentral uuid:3aceef5a-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:3acf1872-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:3acf4252-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:3acf6b88-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3acf9496-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adalimumab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:3acfb96c-7972-11ec-93d9-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4905 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegaptanib is antagonist of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:3acfe0e0-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:4906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fimasartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.377']} DrugCentral uuid:3ad00a34-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:3ad03338-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3ad05cd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3ad0864e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3ad0af66-7972-11ec-93d9-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:3ad0d87e-7972-11ec-93d9-0242ac110002 UniProtKB:Q2NL67 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Unclassified (Poly [ADP-ribose] polymerase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3ad10236-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5Y8 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Unclassified (Mono [ADP-ribose] polymerase PARP16) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:3ad12b30-7972-11ec-93d9-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:3ad1543e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3ad17e6e-7972-11ec-93d9-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:3ad1a876-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:3ad1d18e-7972-11ec-93d9-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acotiamide is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:3ad1fa92-7972-11ec-93d9-0242ac110002 UniProtKB:P31358 biolink:molecularly_interacts_with DrugCentral:4909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alemtuzumab is antibody binding of Surface antigen (CAMPATH-1 antigen) DrugCentral uuid:3ad21f40-7972-11ec-93d9-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4910 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felypressin is agonist of GPCR (Vasopressin V1a receptor) DrugCentral uuid:3ad2445c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.85']} DrugCentral uuid:3ad26d60-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WMX2 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir targets Unclassified (Genome polyprotein [Cleaved into: Core protein p21) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.92']} DrugCentral uuid:3ad2975e-7972-11ec-93d9-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.301']} DrugCentral uuid:3ad2c058-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.854']} DrugCentral uuid:3ad2e9fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4914 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasabuvir targets Enzyme (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3ad312e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4914 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasabuvir targets Unclassified (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3ad33be6-7972-11ec-93d9-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:3ad36cb0-7972-11ec-93d9-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3ad36cb0-7972-11ec-93d9-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3ad36cb0-7972-11ec-93d9-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3ad3aec8-7972-11ec-93d9-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['12.301']} DrugCentral uuid:3ad3d7e0-7972-11ec-93d9-0242ac110002 UniProtKB:P49763 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Placenta growth factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.409']} DrugCentral uuid:3ad40120-7972-11ec-93d9-0242ac110002 UniProtKB:P49765 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Vascular endothelial growth factor B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.717']} DrugCentral uuid:3ad42a88-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4917 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramucirumab is antibody binding of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:3ad453aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:3ad47c7c-7972-11ec-93d9-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:3ad4a56c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.71']} DrugCentral uuid:3ad4cf9c-7972-11ec-93d9-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:3ad5003e-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3ad5003e-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3ad5003e-7972-11ec-93d9-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3ad54184-7972-11ec-93d9-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:3ad56cf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:4923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nivolumab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.14']} DrugCentral uuid:3ad59616-7972-11ec-93d9-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:4924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pembrolizumab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:3ad5c30c-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 becaplermin is agonist of Kinase (Platelet-derived growth factor receptor) DrugCentral uuid:3ad5c30c-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 becaplermin is agonist of Kinase (Platelet-derived growth factor receptor) DrugCentral uuid:3ad5f2dc-7972-11ec-93d9-0242ac110002 UniProtKB:P32301 biolink:molecularly_interacts_with DrugCentral:4927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albiglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3ad61d02-7972-11ec-93d9-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albiglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:3ad64606-7972-11ec-93d9-0242ac110002 UniProtKB:P23945 biolink:molecularly_interacts_with DrugCentral:4928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 follitropin is agonist of GPCR (Follicle-stimulating hormone receptor) DrugCentral uuid:3ad66ad2-7972-11ec-93d9-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:4929 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lutropin alfa is agonist of GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.9']} DrugCentral uuid:3ad69426-7972-11ec-93d9-0242ac110002 UniProtKB:P16473 biolink:molecularly_interacts_with DrugCentral:4930 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyrotropin alfa is agonist of GPCR (Thyrotropin receptor) DrugCentral uuid:3ad6b8de-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3ad6e1ec-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3ad70c3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3ad73890-7972-11ec-93d9-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Adrenocorticotropic hormone receptor) DrugCentral uuid:3ad75ed8-7972-11ec-93d9-0242ac110002 UniProtKB:Q64326 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.8']} DrugCentral uuid:3ad78be2-7972-11ec-93d9-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:4933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocilizumab is antibody binding of Membrane receptor (Interleukin-6 receptor) DrugCentral uuid:3ad78be2-7972-11ec-93d9-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:4933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocilizumab is antibody binding of Membrane receptor (Interleukin-6 receptor) DrugCentral uuid:3ad7bc2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16552 biolink:molecularly_interacts_with DrugCentral:4934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secukinumab is antibody binding of Cytokine (Interleukin-17A) DrugCentral uuid:3ad7e128-7972-11ec-93d9-0242ac110002 UniProtKB:P03420 biolink:molecularly_interacts_with DrugCentral:4935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palivizumab is antibody binding of Surface antigen (Fusion glycoprotein F0) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.357']} DrugCentral uuid:3ad80a40-7972-11ec-93d9-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:4936 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parathyroid hormone is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) DrugCentral uuid:3ad82f20-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3ad85892-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:3ad881aa-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3ad8aac2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:3ad8d3f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.721']} DrugCentral uuid:3ad8fe3c-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.319']} DrugCentral uuid:3ad9274a-7972-11ec-93d9-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3ad9506c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.292']} DrugCentral uuid:3ad979a2-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.721']} DrugCentral uuid:3ad9a332-7972-11ec-93d9-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:3ad9ccc2-7972-11ec-93d9-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:3ad9f5ee-7972-11ec-93d9-0242ac110002 UniProtKB:K7XJL6 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3ada2028-7972-11ec-93d9-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.301']} DrugCentral uuid:3ada4a12-7972-11ec-93d9-0242ac110002 UniProtKB:Q99IB8 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:3ada7352-7972-11ec-93d9-0242ac110002 UniProtKB:P01589 biolink:molecularly_interacts_with DrugCentral:4940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 basiliximab is antibody binding of Membrane receptor (Interleukin-2 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:3ada9c56-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3adac686-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3adaefa8-7972-11ec-93d9-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3adb1c80-7972-11ec-93d9-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3adb1c80-7972-11ec-93d9-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3adb5560-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK2/Cyclin A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3adb5560-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK2/Cyclin A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3adb8e90-7972-11ec-93d9-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK6/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3adb8e90-7972-11ec-93d9-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK6/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3adbc3a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.097']} DrugCentral uuid:3adbecbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:3adc1694-7972-11ec-93d9-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3adc3fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:3adc68ba-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:3adc9312-7972-11ec-93d9-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:3adcbd24-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.409']} DrugCentral uuid:3adce628-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:3add0f36-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3add38e4-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3add622e-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.658']} DrugCentral uuid:3add8b3c-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.398']} DrugCentral uuid:3addb45e-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:3adddefc-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.292']} DrugCentral uuid:3ade081e-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:3ade3122-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:3ade5a26-7972-11ec-93d9-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:3ade851e-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.947']} DrugCentral uuid:3adeae36-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.538']} DrugCentral uuid:3aded758-7972-11ec-93d9-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10']} DrugCentral uuid:3adf003e-7972-11ec-93d9-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin is agonist of GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3adf299c-7972-11ec-93d9-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin is agonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3adf52c8-7972-11ec-93d9-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:3adf7bd6-7972-11ec-93d9-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3adfa584-7972-11ec-93d9-0242ac110002 UniProtKB:Q63931 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:3adfceb0-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam targets Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3adff7be-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam targets Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3ae020d6-7972-11ec-93d9-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.155']} DrugCentral uuid:3ae04b74-7972-11ec-93d9-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3ae0750e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.699']} DrugCentral uuid:3ae09e44-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y275 biolink:molecularly_interacts_with DrugCentral:4949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belimumab is antibody binding of Cytokine (Tumor necrosis factor ligand superfamily member 13B) DrugCentral uuid:3ae0c720-7972-11ec-93d9-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:4950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abciximab is antibody binding of Adhesion (Integrin alpha-IIb/beta-3) DrugCentral uuid:3ae0c720-7972-11ec-93d9-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:4950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abciximab is antibody binding of Adhesion (Integrin alpha-IIb/beta-3) DrugCentral uuid:3ae0f718-7972-11ec-93d9-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofatumumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.92']} DrugCentral uuid:3ae1204e-7972-11ec-93d9-0242ac110002 UniProtKB:P01584 biolink:molecularly_interacts_with DrugCentral:4952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canakinumab is antibody binding of Cytokine (Interleukin-1 beta) DrugCentral uuid:3ae14ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:3ae14ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:3ae14ce0-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:3ae18f02-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetuximab is antibody binding of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.41']} DrugCentral uuid:3ae1b914-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panitumumab is agonist of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:3ae1e240-7972-11ec-93d9-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bevacizumab is antibody binding of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:3ae20702-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4957 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pertuzumab is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:3ae22e30-7972-11ec-93d9-0242ac110002 UniProtKB:P16410 biolink:molecularly_interacts_with DrugCentral:4958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipilimumab is antibody binding of Surface antigen (Cytotoxic T-lymphocyte protein 4) DrugCentral uuid:3ae25676-7972-11ec-93d9-0242ac110002 UniProtKB:P20701 biolink:molecularly_interacts_with DrugCentral:4959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efalizumab is antibody binding of Adhesion (Leukocyte adhesion glycoprotein LFA-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.4']} DrugCentral uuid:3ae27fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin degludec is agonist of Kinase (Insulin receptor) DrugCentral uuid:3ae2a4aa-7972-11ec-93d9-0242ac110002 UniProtKB:P13423 biolink:molecularly_interacts_with DrugCentral:4961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raxibacumab is antibody binding of Secreted (Protective antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.556']} DrugCentral uuid:3ae2ceda-7972-11ec-93d9-0242ac110002 UniProtKB:P28908 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is binding agent of Membrane receptor (Tumor necrosis factor receptor superfamily member 8) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae3126e-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae38c62-7972-11ec-93d9-0242ac110002 UniProtKB:O14788 biolink:molecularly_interacts_with DrugCentral:4965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denosumab is antibody binding of Cytokine (Tumor necrosis factor ligand superfamily member 11) DrugCentral uuid:3ae3b50c-7972-11ec-93d9-0242ac110002 UniProtKB:P29460 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-12) DrugCentral uuid:3ae3b50c-7972-11ec-93d9-0242ac110002 UniProtKB:P29460 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-12) DrugCentral uuid:3ae3e860-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:3ae3e860-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:3ae418a8-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 golimumab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:3ae43d88-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 certolizumab pegol is antibody binding of Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.046']} DrugCentral uuid:3ae466b4-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:4969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eculizumab is antibody binding of Secreted (Complement C5) DrugCentral uuid:3ae48fcc-7972-11ec-93d9-0242ac110002 UniProtKB:P05556 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-1) DrugCentral uuid:3ae48fcc-7972-11ec-93d9-0242ac110002 UniProtKB:P05556 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-1) DrugCentral uuid:3ae4c320-7972-11ec-93d9-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) DrugCentral uuid:3ae4c320-7972-11ec-93d9-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) DrugCentral uuid:3ae4f2b4-7972-11ec-93d9-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranibizumab is antibody binding of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:3ae5178a-7972-11ec-93d9-0242ac110002 UniProtKB:P01854 biolink:molecularly_interacts_with DrugCentral:4972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omalizumab is antibody binding of Antibody (Ig epsilon chain C region) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.16']} DrugCentral uuid:3ae5423c-7972-11ec-93d9-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide targets Enzyme (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3ae56b4a-7972-11ec-93d9-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide targets Cytokine (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3ae5946c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.135']} DrugCentral uuid:3ae5bd84-7972-11ec-93d9-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.365']} DrugCentral uuid:3ae5e778-7972-11ec-93d9-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:3ae61090-7972-11ec-93d9-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.022']} DrugCentral uuid:3ae639bc-7972-11ec-93d9-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:3ae66342-7972-11ec-93d9-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.108']} DrugCentral uuid:3ae68c5a-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infliximab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:3ae6b13a-7972-11ec-93d9-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rituximab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:3ae6dc28-7972-11ec-93d9-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone hexacetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:3ae701a8-7972-11ec-93d9-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:4977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siltuximab is antibody binding of Cytokine (Interleukin-6) DrugCentral uuid:3ae72688-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4978 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etanercept is inhibitor of Cytokine (Tumor necrosis factor) DrugCentral uuid:3ae74b72-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4979 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:3ae77048-7972-11ec-93d9-0242ac110002 UniProtKB:P20138 biolink:molecularly_interacts_with DrugCentral:4980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemtuzumab ozogamicin is antibody binding of Surface antigen (Myeloid cell surface antigen CD33) DrugCentral uuid:3ae79618-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin aspart is agonist of Kinase (Insulin receptor) DrugCentral uuid:3ae7beea-7972-11ec-93d9-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vedolizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3ae7beea-7972-11ec-93d9-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vedolizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3ae7f43c-7972-11ec-93d9-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obinutuzumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) DrugCentral uuid:3ae81926-7972-11ec-93d9-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4984 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibritumomab tiuxetan is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.854']} DrugCentral uuid:3ae842c0-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin detemir is agonist of Kinase (Insulin receptor) DrugCentral uuid:3ae8678c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegfilgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:3ae88c6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:3ae8b138-7972-11ec-93d9-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:3ae8db04-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:3ae903e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:3ae92cb2-7972-11ec-93d9-0242ac110002 UniProtKB:P07445 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid targets Unclassified (Steroid Delta-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3ae956d8-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3ae99bca-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3aea153c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4991 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lipegfilgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:3aea3dd2-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vonoprazan is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3aea3dd2-7972-11ec-93d9-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vonoprazan is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3aea734c-7972-11ec-93d9-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:4995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin alfa is agonist of Membrane receptor (Erythropoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11.15']} DrugCentral uuid:3aea9c5a-7972-11ec-93d9-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:4996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romiplostim is agonist of Membrane receptor (Thrombopoietin receptor) DrugCentral uuid:3aeac20c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NBP7 biolink:molecularly_interacts_with DrugCentral:5000 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evolocumab is inhibitor of Enzyme (Proprotein convertase subtilisin/kexin type 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.72']} DrugCentral uuid:3aeaeb24-7972-11ec-93d9-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:3aeb143c-7972-11ec-93d9-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:3aeb3ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:3aeb695a-7972-11ec-93d9-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:3aeb92ae-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:3aebbbe4-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:3aebe592-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin lispro is agonist of Kinase (Insulin receptor) DrugCentral uuid:3aec0a72-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:3aec3376-7972-11ec-93d9-0242ac110002 UniProtKB:P15127 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.71']} DrugCentral uuid:3aec5c84-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human is agonist of Kinase (Insulin receptor) DrugCentral uuid:3aec81e6-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:5005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirodenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.469']} DrugCentral uuid:3aecaae0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3aecd4de-7972-11ec-93d9-0242ac110002 UniProtKB:Q6NS65 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:3aecfe0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.627']} DrugCentral uuid:3aed27f4-7972-11ec-93d9-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin theta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:3aed4cb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q62226 biolink:molecularly_interacts_with DrugCentral:5008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sonidegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:3aed75e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sonidegib is antagonist of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.222']} DrugCentral uuid:3aed9f04-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecasermin targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:3aedc876-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecasermin is agonist of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3aedf1c0-7972-11ec-93d9-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumacaftor is pharmacological chaperone of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.456']} DrugCentral uuid:3aee2276-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:3aee2276-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:3aee2276-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:3aee5d0e-7972-11ec-93d9-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:5012 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacubitril is inhibitor of Enzyme (Neprilysin) DrugCentral uuid:3aee81d0-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trelagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.398']} DrugCentral uuid:3aeeab4c-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3aeed48c-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:3aeeff66-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:3aef2914-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:3aef5222-7972-11ec-93d9-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:3aef7b26-7972-11ec-93d9-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:3aefa4d4-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:3aefcdf6-7972-11ec-93d9-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3aeff718-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:3af020d0-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.857']} DrugCentral uuid:3af049e8-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.721']} DrugCentral uuid:3af072f6-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:3af09c04-7972-11ec-93d9-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:3af0c76a-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:3af0f08c-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3af11ac6-7972-11ec-93d9-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3af143fc-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:3af16d78-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:3af19690-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:3af1bfa8-7972-11ec-93d9-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:3af1e8ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.025']} DrugCentral uuid:3af21278-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.201']} DrugCentral uuid:3af23b9a-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:3af2649e-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:3af28dc0-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:3af2b796-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.523']} DrugCentral uuid:3af2e0b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.921']} DrugCentral uuid:3af309ee-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.328']} DrugCentral uuid:3af33388-7972-11ec-93d9-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegvisomant is antagonist of GPCR (Growth hormone receptor) DrugCentral uuid:3af35854-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NBP7 biolink:molecularly_interacts_with DrugCentral:5016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alirocumab is inhibitor of Enzyme (Proprotein convertase subtilisin/kexin type 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:3af38554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPH3 biolink:molecularly_interacts_with DrugCentral:5017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anakinra is antagonist of Membrane receptor (Interleukin-1 receptor, type I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3af38554-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPH3 biolink:molecularly_interacts_with DrugCentral:5017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anakinra is antagonist of Membrane receptor (Interleukin-1 receptor, type I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3af3ba7e-7972-11ec-93d9-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.93']} DrugCentral uuid:3af3e436-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.516']} DrugCentral uuid:3af40d30-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:3af43652-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:3af45f56-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.049']} DrugCentral uuid:3af48b8e-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.054']} DrugCentral uuid:3af4b5b4-7972-11ec-93d9-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.093']} DrugCentral uuid:3af4ded6-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3af508d4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:3af535fc-7972-11ec-93d9-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sargramostim is agonist of Membrane receptor (Granulocyte macrophage colony-stimulating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.301']} DrugCentral uuid:3af535fc-7972-11ec-93d9-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sargramostim is agonist of Membrane receptor (Granulocyte macrophage colony-stimulating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.301']} DrugCentral uuid:3af56f18-7972-11ec-93d9-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oprelvekin is agonist of Membrane receptor (Interleukin-11 receptor) DrugCentral uuid:3af56f18-7972-11ec-93d9-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oprelvekin is agonist of Membrane receptor (Interleukin-11 receptor) DrugCentral uuid:3af59f4c-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:5027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolapitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:3af5c85a-7972-11ec-93d9-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:5031 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mogamulizumab is antibody binding of GPCR (C-C chemokine receptor type 4) DrugCentral uuid:3af5ed1c-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3af61652-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:3af64096-7972-11ec-93d9-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3af669ae-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3af692ee-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3af6bd1e-7972-11ec-93d9-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3af6e6a4-7972-11ec-93d9-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:3af70fd0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:3af738f2-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:3af76214-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.07']} DrugCentral uuid:3af78bd6-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:3af7b4e4-7972-11ec-93d9-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3af7de24-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:3af80750-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:3af83388-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:3af85c78-7972-11ec-93d9-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.48']} DrugCentral uuid:3af885ae-7972-11ec-93d9-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.12']} DrugCentral uuid:3af8b024-7972-11ec-93d9-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3af8d91e-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3af90236-7972-11ec-93d9-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3af92b44-7972-11ec-93d9-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3af954ca-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3af97de2-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3af9a6f0-7972-11ec-93d9-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:3af9cffe-7972-11ec-93d9-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:3af9fb6e-7972-11ec-93d9-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3afa24d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3afa4dda-7972-11ec-93d9-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3afa7760-7972-11ec-93d9-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3afaa0be-7972-11ec-93d9-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:3afac9b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:3afaf2b2-7972-11ec-93d9-0242ac110002 UniProtKB:A6XA80 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Unclassified (Leukotriene C4 synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3afb1c42-7972-11ec-93d9-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatrem is agonist of GPCR (Growth hormone receptor) DrugCentral uuid:3afb410e-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:3afb65c6-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:3afb8ec0-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib is allosteric modulator of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3afbb88c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:3afbe230-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saroglitazar is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.187']} DrugCentral uuid:3afc0b5c-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saroglitazar is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:3afc3442-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3afc5daa-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:3afc86ae-7972-11ec-93d9-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3afcb0c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3afcdaf0-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:3afd048a-7972-11ec-93d9-0242ac110002 UniProtKB:P58406 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3afd2d7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:3afd5692-7972-11ec-93d9-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:3afd7fa0-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3afdab9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:3afdd4e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant is inverse agonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.796']} DrugCentral uuid:3afdfe12-7972-11ec-93d9-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3afe273e-7972-11ec-93d9-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3afe50a6-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3afe79b4-7972-11ec-93d9-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3afea2cc-7972-11ec-93d9-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3afecc8e-7972-11ec-93d9-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3afef59c-7972-11ec-93d9-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3aff1eb4-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3aff47d6-7972-11ec-93d9-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:3aff7300-7972-11ec-93d9-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:3aff9c4a-7972-11ec-93d9-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:3affc576-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:3affeeac-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.469']} DrugCentral uuid:3b001850-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:3b00421c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.469']} DrugCentral uuid:3b006b2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:3b00941a-7972-11ec-93d9-0242ac110002 UniProtKB:P28843 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:3b00bee0-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:3b00e820-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin glulisine is agonist of Kinase (Insulin receptor) DrugCentral uuid:3b010d0a-7972-11ec-93d9-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:5059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lusutrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.076']} DrugCentral uuid:3b0136a4-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5060 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esflurbiprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3b015fa8-7972-11ec-93d9-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:5060 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esflurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3b0188d4-7972-11ec-93d9-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:5061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepolizumab is antibody binding of Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:3b01b1ec-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:3b01db4a-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3b020462-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3b022d66-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:3b025638-7972-11ec-93d9-0242ac110002 UniProtKB:P53634 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Enzyme (Dipeptidyl peptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:3b02800e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3b02aa70-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3b02d388-7972-11ec-93d9-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:5063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daratumumab is antibody binding of Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3b02fce6-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:5064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 climbazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3b032842-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trenbolone hexahydrobenzylcarbonate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:3b035164-7972-11ec-93d9-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:5065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trenbolone hexahydrobenzylcarbonate targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:3b037a72-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenecteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:3b039f34-7972-11ec-93d9-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.509']} DrugCentral uuid:3b03c89c-7972-11ec-93d9-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:3b03f1be-7972-11ec-93d9-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:3b041ac2-7972-11ec-93d9-0242ac110002 UniProtKB:Q02563 biolink:molecularly_interacts_with DrugCentral:5068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivaracetam is inhibitor of Unclassified (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3b044466-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L0J3 biolink:molecularly_interacts_with DrugCentral:5068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivaracetam is modulator of Transporter (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3b046d9c-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 necitumumab is antibody binding of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.49']} DrugCentral uuid:3b0496aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NQ25 biolink:molecularly_interacts_with DrugCentral:5072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elotuzumab is antibody binding of Membrane receptor (SLAM family member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3b04c0b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:5075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lesinurad is inhibitor of Transporter (Solute carrier family 22 member 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.432']} DrugCentral uuid:3b04ebbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:5075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lesinurad is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.137']} DrugCentral uuid:3b0514e0-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3b053dda-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3b0566de-7972-11ec-93d9-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3b059032-7972-11ec-93d9-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3b05b95e-7972-11ec-93d9-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:3b05e24e-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3b060b66-7972-11ec-93d9-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:3b06351e-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lobeglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:3b065e22-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lobeglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:3b068712-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:3b06afee-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:3b06da00-7972-11ec-93d9-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.523']} DrugCentral uuid:3b070318-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:3b072c30-7972-11ec-93d9-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.523']} DrugCentral uuid:3b075598-7972-11ec-93d9-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:3b077e9c-7972-11ec-93d9-0242ac110002 UniProtKB:K7XJL6 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:3b07a7c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q0ZMF1 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:3b07d0f4-7972-11ec-93d9-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.301']} DrugCentral uuid:3b07fab6-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.398']} DrugCentral uuid:3b0823c4-7972-11ec-93d9-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.523']} DrugCentral uuid:3b084cc8-7972-11ec-93d9-0242ac110002 UniProtKB:Q16552 biolink:molecularly_interacts_with DrugCentral:5083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixekizumab is antibody binding of Cytokine (Interleukin-17A) DrugCentral uuid:3b087946-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:3b087946-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:3b087946-7972-11ec-93d9-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:3b08b7b2-7972-11ec-93d9-0242ac110002 UniProtKB:P06729 biolink:molecularly_interacts_with DrugCentral:5088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alefacept is inhibitor of Surface antigen (T-cell surface antigen CD2) DrugCentral uuid:3b08dc92-7972-11ec-93d9-0242ac110002 UniProtKB:P33681 biolink:molecularly_interacts_with DrugCentral:5089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD80) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3b0905aa-7972-11ec-93d9-0242ac110002 UniProtKB:P42081 biolink:molecularly_interacts_with DrugCentral:5089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD86) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3b092f26-7972-11ec-93d9-0242ac110002 UniProtKB:P33681 biolink:molecularly_interacts_with DrugCentral:5091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD80) DrugCentral uuid:3b0953e8-7972-11ec-93d9-0242ac110002 UniProtKB:P42081 biolink:molecularly_interacts_with DrugCentral:5091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD86) DrugCentral uuid:3b09794a-7972-11ec-93d9-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:5093 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reslizumab is antibody binding of Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.092']} DrugCentral uuid:3b09a276-7972-11ec-93d9-0242ac110002 UniProtKB:P13423 biolink:molecularly_interacts_with DrugCentral:5094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obiltoxaximab is antibody binding of Secreted (Protective antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.481']} DrugCentral uuid:3b09cbf2-7972-11ec-93d9-0242ac110002 UniProtKB:P01583 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Cytokine (Interleukin-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.854']} DrugCentral uuid:3b09f528-7972-11ec-93d9-0242ac110002 UniProtKB:P18510 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Unclassified (Interleukin-1 receptor antagonist protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.215']} DrugCentral uuid:3b0a1e4a-7972-11ec-93d9-0242ac110002 UniProtKB:P01584 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Cytokine (Interleukin-1 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['12.301']} DrugCentral uuid:3b0a476c-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urokinase is activator of Enzyme (Plasminogen) DrugCentral uuid:3b0a6d28-7972-11ec-93d9-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3b0a9636-7972-11ec-93d9-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3b0abf44-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HCG7 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3b0ae848-7972-11ec-93d9-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3b0b1200-7972-11ec-93d9-0242ac110002 UniProtKB:P35573 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3b0b3b22-7972-11ec-93d9-0242ac110002 UniProtKB:P09848 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:3b0b6412-7972-11ec-93d9-0242ac110002 UniProtKB:P16278 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:3b0b8d02-7972-11ec-93d9-0242ac110002 UniProtKB:Q59750 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3b0bb688-7972-11ec-93d9-0242ac110002 UniProtKB:Q02401 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:3b0bdf96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UUZ4 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Alpha-galactosidase C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:3b0c08a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q42656 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Alpha-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3b0c3194-7972-11ec-93d9-0242ac110002 UniProtKB:D3ZUM4 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:3b0c5b38-7972-11ec-93d9-0242ac110002 UniProtKB:Q8VNN2 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:3b0c846e-7972-11ec-93d9-0242ac110002 UniProtKB:P06280 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat is pharmacological chaperone of Enzyme (Alpha-galactosidase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:3b0cae6c-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chromic chloride targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:3b0cd810-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chromic chloride targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:3b0d0128-7972-11ec-93d9-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:3b0d2a36-7972-11ec-93d9-0242ac110002 UniProtKB:Q92843 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Apoptosis regulator Bcl-W) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:3b0d5362-7972-11ec-93d9-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:3b0d80d0-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b0d80d0-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b0db406-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b0db406-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b0de732-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b0de732-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b0e1914-7972-11ec-93d9-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:3b0e3de0-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimavanserin is inverse agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3b0e670c-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimavanserin is inverse agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3b0e9010-7972-11ec-93d9-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3b0eb9f0-7972-11ec-93d9-0242ac110002 UniProtKB:O88587 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3b0ee344-7972-11ec-93d9-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:3b0f0c48-7972-11ec-93d9-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:5144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gluconolactone targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:3b0f356a-7972-11ec-93d9-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:5149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choriogonadotropin alfa is agonist of GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:3b0f5ab8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atezolizumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.39']} DrugCentral uuid:3b0f83ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:3b0fad7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:3b0fd6a0-7972-11ec-93d9-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.796']} DrugCentral uuid:3b100300-7972-11ec-93d9-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.854']} DrugCentral uuid:3b102c18-7972-11ec-93d9-0242ac110002 UniProtKB:Q99IB8 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.979']} DrugCentral uuid:3b105530-7972-11ec-93d9-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.046']} DrugCentral uuid:3b108000-7972-11ec-93d9-0242ac110002 UniProtKB:Q81495 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:3b10a918-7972-11ec-93d9-0242ac110002 UniProtKB:Q9DHD6 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:3b10d23a-7972-11ec-93d9-0242ac110002 UniProtKB:O91936 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.426']} DrugCentral uuid:3b10fb5c-7972-11ec-93d9-0242ac110002 UniProtKB:Q5I2N3 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.097']} DrugCentral uuid:3b1124ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:5155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obeticholic acid targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3b114dbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:5155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obeticholic acid is agonist of Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.004']} DrugCentral uuid:3b1176cc-7972-11ec-93d9-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darbepoetin alfa is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:3b119f76-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b119f76-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b11d252-7972-11ec-93d9-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin beta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:3b11fdcc-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b11fdcc-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b122d42-7972-11ec-93d9-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxy polyethylene glycol-epoetin beta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:3b1252d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:5167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenograstim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:3b127798-7972-11ec-93d9-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:5169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eldecalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:3b129c64-7972-11ec-93d9-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:5169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eldecalcitol is agonist of Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:3b12c5ae-7972-11ec-93d9-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin zeta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:3b12ead4-7972-11ec-93d9-0242ac110002 UniProtKB:P05362 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast targets Unclassified (Intercellular adhesion molecule 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:3b1317ca-7972-11ec-93d9-0242ac110002 UniProtKB:P05107 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast is antagonist of Adhesion (Integrin alpha-L/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:3b1317ca-7972-11ec-93d9-0242ac110002 UniProtKB:P05107 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast is antagonist of Adhesion (Integrin alpha-L/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:3b1354c4-7972-11ec-93d9-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:3b1354c4-7972-11ec-93d9-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:3b1354c4-7972-11ec-93d9-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:3b139506-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NAC3 biolink:molecularly_interacts_with DrugCentral:5179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodalumab is antibody binding of Membrane receptor (Interleukin-17 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:3b139506-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NAC3 biolink:molecularly_interacts_with DrugCentral:5179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodalumab is antibody binding of Membrane receptor (Interleukin-17 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:3b13ca4e-7972-11ec-93d9-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:5181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etelcalcetide is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:3b13f352-7972-11ec-93d9-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eteplirsen is binding agent of RNA (exon 51 of dystrophin pre-mRNA) DrugCentral uuid:3b141918-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaratumab is antibody binding of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.4']} DrugCentral uuid:3b144294-7972-11ec-93d9-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallium (68Ga) edotreotide is antagonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3b146c4c-7972-11ec-93d9-0242ac110002 UniProtKB:P18177 biolink:molecularly_interacts_with DrugCentral:5186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezlotoxumab is antibody binding of Enzyme (Toxin B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:3b149578-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 radotinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.514']} DrugCentral uuid:3b14bed6-7972-11ec-93d9-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3b14e7da-7972-11ec-93d9-0242ac110002 UniProtKB:Q13946 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole targets Enzyme (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:3b151c96-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3b151c96-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3b151c96-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3b151c96-7972-11ec-93d9-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3b156ade-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3b159400-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3b15bd2c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3b15e644-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.87']} DrugCentral uuid:3b160ff2-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.276']} DrugCentral uuid:3b16390a-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.229']} DrugCentral uuid:3b16622c-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.244']} DrugCentral uuid:3b168b3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3b16b4a2-7972-11ec-93d9-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:3b16ddb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3b1706b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3b1730ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3b175a56-7972-11ec-93d9-0242ac110002 UniProtKB:Q460N5 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3b17836e-7972-11ec-93d9-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:3b17ac7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:3b17d6de-7972-11ec-93d9-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:3b17fff6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3b1828fa-7972-11ec-93d9-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3b1851f4-7972-11ec-93d9-0242ac110002 UniProtKB:P19438 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide targets Unclassified (Tumor necrosis factor receptor superfamily member 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:3b187b7a-7972-11ec-93d9-0242ac110002 UniProtKB:P25092 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.721']} DrugCentral uuid:3b18a47e-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icotinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:3b18cd6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmutinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3b18f7da-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmutinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.036']} DrugCentral uuid:3b1923e0-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3b194fd2-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.368']} DrugCentral uuid:3b197944-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.276']} DrugCentral uuid:3b19a2ca-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.886']} DrugCentral uuid:3b19cbd8-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3b19f5b8-7972-11ec-93d9-0242ac110002 UniProtKB:P17752 biolink:molecularly_interacts_with DrugCentral:5214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telotristat ethyl is inhibitor of Enzyme (Tryptophan 5-hydroxylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:3b1a1eb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclabuvir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:3b1a4860-7972-11ec-93d9-0242ac110002 UniProtKB:O39930 biolink:molecularly_interacts_with DrugCentral:5215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclabuvir targets Unclassified (RNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3b1a7178-7972-11ec-93d9-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3b1a9a86-7972-11ec-93d9-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3b1ac380-7972-11ec-93d9-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.47']} DrugCentral uuid:3b1aed74-7972-11ec-93d9-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:3b1b1696-7972-11ec-93d9-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:3b1b3f90-7972-11ec-93d9-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:3b1b6984-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:3b1b9328-7972-11ec-93d9-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.409']} DrugCentral uuid:3b1bbd3a-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3b1be634-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naldemedine is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:3b1c0f60-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naldemedine is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:3b1c3936-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5221 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avelumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) DrugCentral uuid:3b1c5de4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:3b1c86ca-7972-11ec-93d9-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3b1cb0d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3b1cda1c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3b1d0348-7972-11ec-93d9-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3b1d2c56-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3b1d560e-7972-11ec-93d9-0242ac110002 UniProtKB:Q460N5 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:3b1d7f26-7972-11ec-93d9-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3b1da82a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:3b1dd124-7972-11ec-93d9-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:3b1dfae6-7972-11ec-93d9-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:5223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ocrelizumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.08']} DrugCentral uuid:3b1e2480-7972-11ec-93d9-0242ac110002 UniProtKB:P24394 biolink:molecularly_interacts_with DrugCentral:5224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dupilumab is antibody binding of Membrane receptor (Interleukin-4 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11.06']} DrugCentral uuid:3b1e4d7a-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:5226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deutetrabenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:3b1e723c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:5227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valbenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:3b1e9e10-7972-11ec-93d9-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:5227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valbenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.523']} DrugCentral uuid:3b1ec73c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8T9Z7 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:3b1ef18a-7972-11ec-93d9-0242ac110002 UniProtKB:P55859 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.64']} DrugCentral uuid:3b1f1aca-7972-11ec-93d9-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine is inhibitor of Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.143']} DrugCentral uuid:3b1f4446-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3b1f6d72-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3b1f9676-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3b1fc16e-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:3b1fea72-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:3b201394-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b203c8e-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3b2066be-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3b208fc2-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3b20b8d0-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3b20e1de-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:3b210b64-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3b21345e-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3b215dda-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3b2186ca-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3b21b096-7972-11ec-93d9-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:3b21d9a4-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3b2202a8-7972-11ec-93d9-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3b222c56-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3b22564a-7972-11ec-93d9-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b227f4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b22a870-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3b22d1d8-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3b22fae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3b232408-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:3b234d16-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3b2376ba-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b239fdc-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3b23c9da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3b23f2fc-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3b241dc2-7972-11ec-93d9-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3b2446d0-7972-11ec-93d9-0242ac110002 UniProtKB:P22694 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3b247074-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3b24998c-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b24c31c-7972-11ec-93d9-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:3b24ec3e-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3b251678-7972-11ec-93d9-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:3b254044-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3b256948-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3b259260-7972-11ec-93d9-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3b25bb5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3b25e5a8-7972-11ec-93d9-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3b260ea2-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3b2637c4-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3b2660be-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3b268a44-7972-11ec-93d9-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3b26b348-7972-11ec-93d9-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3b26dc56-7972-11ec-93d9-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3b270550-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3b272f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3b27582a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3b27812e-7972-11ec-93d9-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3b27abfe-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3b27d502-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b27fe1a-7972-11ec-93d9-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:3b282728-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:3b285090-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3b287994-7972-11ec-93d9-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3b28a298-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3b28cbb0-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3b28f55e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:3b291e80-7972-11ec-93d9-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3b29478e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3b297088-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3b299bb2-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:3b29c4ca-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3b29edb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3b2a16c8-7972-11ec-93d9-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3b2a403a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3b2a6952-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b2a9256-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3b2abc2c-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3b2ae526-7972-11ec-93d9-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3b2b0f92-7972-11ec-93d9-0242ac110002 UniProtKB:P49761 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3b2b3918-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3b2b6352-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3b2b8c6a-7972-11ec-93d9-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b2bb668-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3b2bdf62-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3b2c08de-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b2c31d8-7972-11ec-93d9-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3b2c5ae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3b2c83d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3b2cad98-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3b2cd6a6-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3b2cffaa-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:3b2d296c-7972-11ec-93d9-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:3b2d5284-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3b2d7ba6-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b2da4be-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3b2dce26-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3b2df73e-7972-11ec-93d9-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3b2e2038-7972-11ec-93d9-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3b2e495a-7972-11ec-93d9-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3b2e72fe-7972-11ec-93d9-0242ac110002 UniProtKB:P49840 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Glycogen synthase kinase-3 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3b2e9c0c-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3b2ec52e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:3b2eee32-7972-11ec-93d9-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3b2f19f2-7972-11ec-93d9-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3b2f431e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3b2f6c36-7972-11ec-93d9-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:3b2f9616-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3b2fbf9c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3b2fe8aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3b3011ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:3b303b7a-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3b30647e-7972-11ec-93d9-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3b308d8c-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3b30b690-7972-11ec-93d9-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3b30e03e-7972-11ec-93d9-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:3b310956-7972-11ec-93d9-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3b31339a-7972-11ec-93d9-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3b315c9e-7972-11ec-93d9-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3b318606-7972-11ec-93d9-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b31af28-7972-11ec-93d9-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3b31d836-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b3201bc-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3b322b4c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3b32545a-7972-11ec-93d9-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3b327d4a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3b32a716-7972-11ec-93d9-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3b32d042-7972-11ec-93d9-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3b32f93c-7972-11ec-93d9-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3b33224a-7972-11ec-93d9-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3b334bc6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:3b3375c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3b339ec8-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3b33c7e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3b33f184-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:3b341a9c-7972-11ec-93d9-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3b3443aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3b346cb8-7972-11ec-93d9-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:3b349832-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3b34c14a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y243 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-gamma serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3b34ea62-7972-11ec-93d9-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3b35138e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3b353d0a-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3b356618-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3b358f12-7972-11ec-93d9-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:3b35b8d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:3b35e1c4-7972-11ec-93d9-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:3b360ae6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b3633f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3b365e88-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3b3687dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDC3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase BRSK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b36b0d6-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3b36d9d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3b370342-7972-11ec-93d9-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3b372d7c-7972-11ec-93d9-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3b375680-7972-11ec-93d9-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3b37809c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3b37aa5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3b37d376-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3b37fc84-7972-11ec-93d9-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3b382682-7972-11ec-93d9-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3b385224-7972-11ec-93d9-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3b387b3c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b38a4cc-7972-11ec-93d9-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3b38ce16-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IWQ3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase BRSK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3b38f724-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3b392028-7972-11ec-93d9-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b394922-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3b3972d0-7972-11ec-93d9-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3b399be8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.13']} DrugCentral uuid:3b39c4f6-7972-11ec-93d9-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3b39edfa-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3b3a180c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3b3a411a-7972-11ec-93d9-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3b3a6a28-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3b3a932c-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3b3abc9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:3b3ae5ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3b3b0eb0-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b3b387c-7972-11ec-93d9-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b3b618a-7972-11ec-93d9-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3b3b8b7e-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3b3bb478-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3b3bdf70-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b3c08ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b3c31d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3b3c5ae0-7972-11ec-93d9-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3b3c8466-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3b3cad60-7972-11ec-93d9-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3b3cd682-7972-11ec-93d9-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3b3cffa4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3b3d2966-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3b3d53be-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3b3d7cd6-7972-11ec-93d9-0242ac110002 UniProtKB:O43172 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Nuclear other (U4/U6 small nuclear ribonucleoprotein Prp4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:3b3da6de-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:3b3dd00a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3b3df918-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3b3e2230-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3b3e4b84-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3b3e7488-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b3e9d82-7972-11ec-93d9-0242ac110002 UniProtKB:O00750 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3b3ec690-7972-11ec-93d9-0242ac110002 UniProtKB:O75747 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3b3ef03e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:3b3f1938-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3b3f4246-7972-11ec-93d9-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:3b3f6c4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3b3f98a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b3fc2a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:3b3febb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3b401522-7972-11ec-93d9-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3b403e4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3b406752-7972-11ec-93d9-0242ac110002 UniProtKB:P51817 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit PRKX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3b409060-7972-11ec-93d9-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3b40b9fa-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:3b40e330-7972-11ec-93d9-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:5232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abaloparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3b410c3e-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:3b413542-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:3b416008-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.137']} DrugCentral uuid:3b41890c-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:3b41b224-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.721']} DrugCentral uuid:3b41db32-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.222']} DrugCentral uuid:3b4204ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 durvalumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) DrugCentral uuid:3b42297a-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5235 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenegermin is agonist of Kinase (High affinity nerve growth factor receptor) DrugCentral uuid:3b424e50-7972-11ec-93d9-0242ac110002 UniProtKB:P08138 biolink:molecularly_interacts_with DrugCentral:5235 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenegermin is agonist of Membrane receptor (Tumor necrosis factor receptor superfamily member 16) DrugCentral uuid:3b427704-7972-11ec-93d9-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarilumab is antibody binding of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.1']} DrugCentral uuid:3b427704-7972-11ec-93d9-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarilumab is antibody binding of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.1']} DrugCentral uuid:3b42ad0a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evogliptin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:3b42d618-7972-11ec-93d9-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evogliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:3b42ff30-7972-11ec-93d9-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3b432abe-7972-11ec-93d9-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3b4354e4-7972-11ec-93d9-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.081']} DrugCentral uuid:3b437df2-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.081']} DrugCentral uuid:3b43a714-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b43d09a-7972-11ec-93d9-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:3b43f994-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:3b4422b6-7972-11ec-93d9-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxilaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.42']} DrugCentral uuid:3b444bd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q81495 biolink:molecularly_interacts_with DrugCentral:5242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxilaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.18']} DrugCentral uuid:3b4475b8-7972-11ec-93d9-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pibrentasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.19']} DrugCentral uuid:3b449ec6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WMX2 biolink:molecularly_interacts_with DrugCentral:5244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pibrentasvir targets Unclassified (Genome polyprotein [Cleaved into: Core protein p21) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3b44c7c0-7972-11ec-93d9-0242ac110002 UniProtKB:P23945 biolink:molecularly_interacts_with DrugCentral:5245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corifollitropin alfa is agonist of GPCR (Follicle-stimulating hormone receptor) DrugCentral uuid:3b44f0e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5246 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guselkumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:3b44f0e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5246 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guselkumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:3b4522b0-7972-11ec-93d9-0242ac110002 UniProtKB:P20273 biolink:molecularly_interacts_with DrugCentral:5247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inotuzumab ozogamicin is antibody binding of Membrane receptor (B-cell receptor CD22) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3b454be6-7972-11ec-93d9-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:3b4574ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.801']} DrugCentral uuid:3b459e48-7972-11ec-93d9-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3b45c738-7972-11ec-93d9-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:3b45f046-7972-11ec-93d9-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:3b46194a-7972-11ec-93d9-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:3b46430c-7972-11ec-93d9-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib targets Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3b466c38-7972-11ec-93d9-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib targets Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3b469564-7972-11ec-93d9-0242ac110002 UniProtKB:P48735 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib is inhibitor of Enzyme (Isocitrate dehydrogenase [NADP], mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3b46be68-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b46e960-7972-11ec-93d9-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:3b471264-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3b473c6c-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3b476570-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b478eec-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3b47b804-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3b47e126-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b480ade-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3b4833ec-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3b485cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3b4885f4-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3b48afde-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3b48d8e2-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3b4901fa-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3b492c34-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:3b4955ba-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:3b497eb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3b49a7b8-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3b49d0da-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:3b49faa6-7972-11ec-93d9-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3b4a23a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3b4a4cb8-7972-11ec-93d9-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3b4a76c0-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:3b4a9fec-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:3b4ac8fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3b4af1fe-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3b4b1be8-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3b4b460e-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3b4b6f08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3b4b9820-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:3b4bc1f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:3b4beafa-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3b4c1426-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:3b4c3d3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b4c6836-7972-11ec-93d9-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3b4c914e-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3b4cba52-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:3b4ce374-7972-11ec-93d9-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3b4d0cf0-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3b4d3612-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:3b4d5f2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3b4d88ec-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3b4db1f0-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:3b4ddaea-7972-11ec-93d9-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:3b4e0402-7972-11ec-93d9-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3b4e2e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3b4e579a-7972-11ec-93d9-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3b4e80a8-7972-11ec-93d9-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3b4ea9ac-7972-11ec-93d9-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3b4ed314-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3b4efc22-7972-11ec-93d9-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3b4f2684-7972-11ec-93d9-0242ac110002 UniProtKB:P78368 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3b4f5078-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6M4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3b4f7a4e-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3b4fa35c-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:3b4fcc60-7972-11ec-93d9-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3b4ff668-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:3b5021d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:3b504adc-7972-11ec-93d9-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3b5073e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3b509d3e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3b50c660-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3b50ef78-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3b511872-7972-11ec-93d9-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3b51423e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:3b516b4c-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3b519464-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3b51bd5e-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3b51e888-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3b521218-7972-11ec-93d9-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3b523b30-7972-11ec-93d9-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3b526498-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:3b528dba-7972-11ec-93d9-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3b52b6be-7972-11ec-93d9-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3b52dfea-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3b530998-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3b5332ba-7972-11ec-93d9-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3b535cc2-7972-11ec-93d9-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3b5385d0-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:3b53afd8-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3b53d8dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3b5401e0-7972-11ec-93d9-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3b542b16-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3b545492-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3b547da0-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b54a6a4-7972-11ec-93d9-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:3b54cfb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:3b54f974-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3b55228c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:3b554cd0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3b5576ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3b559fbe-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:3b55c8c2-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:3b55f1d0-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3b561b56-7972-11ec-93d9-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3b564450-7972-11ec-93d9-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3b566d68-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3b569662-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3b56c024-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY57 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 32B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3b56e946-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.62']} DrugCentral uuid:3b571272-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.036']} DrugCentral uuid:3b573b8a-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.229']} DrugCentral uuid:3b5766a0-7972-11ec-93d9-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:3b578f9a-7972-11ec-93d9-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.432']} DrugCentral uuid:3b57b8d0-7972-11ec-93d9-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.194']} DrugCentral uuid:3b57e22e-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:3b580b46-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:3b5834c2-7972-11ec-93d9-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:5257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butylphthalide is blocker of Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:3b585dc6-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.65']} DrugCentral uuid:3b58874c-7972-11ec-93d9-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:3b58b05a-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.764']} DrugCentral uuid:3b58d968-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.788']} DrugCentral uuid:3b590276-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.375']} DrugCentral uuid:3b592d96-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.866']} DrugCentral uuid:3b5956f4-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.524']} DrugCentral uuid:3b597ff8-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.678']} DrugCentral uuid:3b59a91a-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.796']} DrugCentral uuid:3b59d296-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:3b59fb90-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:3b5a249e-7972-11ec-93d9-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3b5a4dac-7972-11ec-93d9-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3b5a7764-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3b5aa07c-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3b5ac96c-7972-11ec-93d9-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3b5af388-7972-11ec-93d9-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:3b5b1cf0-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:3b5b46f8-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:3b5b711e-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3b5b9a7c-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:3b5bc36c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:3b5bec70-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:3b5c1574-7972-11ec-93d9-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.032']} DrugCentral uuid:3b5c3f40-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.434']} DrugCentral uuid:3b5c684e-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.292']} DrugCentral uuid:3b5c9152-7972-11ec-93d9-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:5261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprostene bunod targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:3b5cba74-7972-11ec-93d9-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:5261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprostene bunod is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3b5cee7c-7972-11ec-93d9-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:3b5cee7c-7972-11ec-93d9-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:3b5cee7c-7972-11ec-93d9-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:3b5d2fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01344 biolink:molecularly_interacts_with DrugCentral:5263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benralizumab is antibody binding of Membrane receptor (Interleukin-5 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.959']} DrugCentral uuid:3b5d58ee-7972-11ec-93d9-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:5267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 semaglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.42']} DrugCentral uuid:3b5d82ec-7972-11ec-93d9-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:5268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emicizumab is antibody binding of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.73']} DrugCentral uuid:3b5dac0e-7972-11ec-93d9-0242ac110002 UniProtKB:P00740 biolink:molecularly_interacts_with DrugCentral:5268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emicizumab is antibody binding of Enzyme (Coagulation factor IX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3b5dd508-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netarsudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:3b5dfed4-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netarsudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.377']} DrugCentral uuid:3b5e27ec-7972-11ec-93d9-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin targets Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.94']} DrugCentral uuid:3b5e50fa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NY91 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin targets Transporter (Low affinity sodium-glucose cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.06']} DrugCentral uuid:3b5e79fe-7972-11ec-93d9-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.708']} DrugCentral uuid:3b5ea4ba-7972-11ec-93d9-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.057']} DrugCentral uuid:3b5ece04-7972-11ec-93d9-0242ac110002 UniProtKB:Q92847 biolink:molecularly_interacts_with DrugCentral:5271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macimorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:3b5ef7ee-7972-11ec-93d9-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II is agonist of GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.2']} DrugCentral uuid:3b5f211a-7972-11ec-93d9-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:3b5f4aaa-7972-11ec-93d9-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:3b5f73c2-7972-11ec-93d9-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3b5f9cd0-7972-11ec-93d9-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II is agonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3b5fc5d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:3b5fef8c-7972-11ec-93d9-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir targets Unclassified (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:3b6018a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.125']} DrugCentral uuid:3b60419e-7972-11ec-93d9-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lutetium (177Lu) oxodotreotide is agonist of GPCR (Somatostatin receptor type 2) DrugCentral uuid:3b60669c-7972-11ec-93d9-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tezacaftor is pharmacological chaperone of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3b609072-7972-11ec-93d9-0242ac110002 UniProtKB:Q12908 biolink:molecularly_interacts_with DrugCentral:5277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elobixibat is inhibitor of Transporter (Ileal sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.276']} DrugCentral uuid:3b60b98a-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apalutamide is antagonist of Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3b60e2c0-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apalutamide is inhibitor of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:3b610c32-7972-11ec-93d9-0242ac110002 UniProtKB:P01730 biolink:molecularly_interacts_with DrugCentral:5279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibalizumab is antibody binding of Membrane receptor (T-cell surface glycoprotein CD4) DrugCentral uuid:3b613248-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3b615b56-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:3b618478-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3b61ae30-7972-11ec-93d9-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.092']} DrugCentral uuid:3b61d748-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.387']} DrugCentral uuid:3b62043e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tildrakizumab is antibody binding of Cytokine (Interleukin-23) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:3b62043e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tildrakizumab is antibody binding of Cytokine (Interleukin-23) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:3b6239ae-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZV9 biolink:molecularly_interacts_with DrugCentral:5282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 burosumab is antibody binding of Secreted (Fibroblast growth factor 23) DrugCentral uuid:3b62612c-7972-11ec-93d9-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:5283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosnetupitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.022']} DrugCentral uuid:3b628eb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erenumab is antibody binding of GPCR (Calcitonin-gene-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.699']} DrugCentral uuid:3b628eb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erenumab is antibody binding of GPCR (Calcitonin-gene-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.699']} DrugCentral uuid:3b62c4f0-7972-11ec-93d9-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:5285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avatrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:3b62ee62-7972-11ec-93d9-0242ac110002 UniProtKB:Q25634 biolink:molecularly_interacts_with DrugCentral:5286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxidectin is inhibitor of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:3b631310-7972-11ec-93d9-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3b633c3c-7972-11ec-93d9-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3b636536-7972-11ec-93d9-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is agonist of GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:3b638ee4-7972-11ec-93d9-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:3b63b7fc-7972-11ec-93d9-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3b63e11e-7972-11ec-93d9-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:3b640a36-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3b643678-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5S1 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:3b645f90-7972-11ec-93d9-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:3b6488bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is inhibitor of Ion channel (Transient receptor potential cation channel subfamily V member 1) DrugCentral uuid:3b64ad7e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is antagonist of GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:3b64d6f0-7972-11ec-93d9-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3b64ffea-7972-11ec-93d9-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib is inhibitor of Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:3b65290c-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.328']} DrugCentral uuid:3b6552c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 binimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3b657bdc-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 binimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:3b65a512-7972-11ec-93d9-0242ac110002 UniProtKB:P33815 biolink:molecularly_interacts_with DrugCentral:5291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tecovirimat is inhibitor of Viral envelope protein (Envelope protein F13) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.382']} DrugCentral uuid:3b65ce0c-7972-11ec-93d9-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5292 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivosidenib is inhibitor of Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.149']} DrugCentral uuid:3b65f7b0-7972-11ec-93d9-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3b6620aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q8SPZ1 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:3b6649d6-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:3b6672c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3b669c2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine targets Unclassified (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3b66c640-7972-11ec-93d9-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:3b66f070-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3b671988-7972-11ec-93d9-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3b6743e0-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.638']} DrugCentral uuid:3b676d16-7972-11ec-93d9-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:3b679638-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:3b67bfd2-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3b67e912-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3b681248-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:3b683b56-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:3b6864c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.133']} DrugCentral uuid:3b688de0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talazoparib tosylate is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:3b68b716-7972-11ec-93d9-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talazoparib tosylate is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:3b68e042-7972-11ec-93d9-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:5301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baloxavir marboxil is inhibitor of Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.854']} DrugCentral uuid:3b690a18-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3b693344-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.959']} DrugCentral uuid:3b695c66-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:3b69856a-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3b69b012-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:3b69d934-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:3b6a024c-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3b6a2b6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:3b6a54ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.854']} DrugCentral uuid:3b6a7e0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:3b6aa81e-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.569']} DrugCentral uuid:3b6ad1ea-7972-11ec-93d9-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:3b6afaee-7972-11ec-93d9-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:3b6b2424-7972-11ec-93d9-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3b6b4d32-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:3b6b7802-7972-11ec-93d9-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:3b6ba232-7972-11ec-93d9-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3b6bcb40-7972-11ec-93d9-0242ac110002 UniProtKB:P56726 biolink:molecularly_interacts_with DrugCentral:5304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glasdegib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3b6bf458-7972-11ec-93d9-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glasdegib is antagonist of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:3b6c1de8-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.187']} DrugCentral uuid:3b6c470a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.092']} DrugCentral uuid:3b6c7022-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.975']} DrugCentral uuid:3b6c99b2-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:3b6cc360-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3b6cecd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3b6d1720-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3b6d410a-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3b6d6c0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3b6d9588-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3b6dbea0-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:3b6de812-7972-11ec-93d9-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:5307 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evocalcet is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.032']} DrugCentral uuid:3b6e110c-7972-11ec-93d9-0242ac110002 UniProtKB:P04275 biolink:molecularly_interacts_with DrugCentral:5308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caplacizumab is antibody binding of Unclassified (von Willebrand factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.509']} DrugCentral uuid:3b6e3a38-7972-11ec-93d9-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:5309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanadelumab is antibody binding of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:3b6e633c-7972-11ec-93d9-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:3b6e8dda-7972-11ec-93d9-0242ac110002 UniProtKB:O02662 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:3b6eb6d4-7972-11ec-93d9-0242ac110002 UniProtKB:Q28524 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:3b6edfec-7972-11ec-93d9-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:3b6f0968-7972-11ec-93d9-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omidenepag isopropyl is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.081']} DrugCentral uuid:3b6f34d8-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:5313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 patisiran is antisense inhibitor of RNA (transthyretin (TTR) mRNA) DrugCentral uuid:3b6f599a-7972-11ec-93d9-0242ac110002 UniProtKB:P20273 biolink:molecularly_interacts_with DrugCentral:5314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxetumomab pasudotox is binding agent of Membrane receptor (B-cell receptor CD22) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3b6f82a8-7972-11ec-93d9-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5315 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fremanezumab is antibody binding of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:3b6fabac-7972-11ec-93d9-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galcanezumab is antibody binding of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3b6fd53c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:5317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cemiplimab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.102']} DrugCentral uuid:3b6ffe5e-7972-11ec-93d9-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:5319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inotersen is antisense inhibitor of RNA (transthyretin (TTR) mRNA) DrugCentral uuid:3b70232a-7972-11ec-93d9-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:5320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emapalumab is antibody binding of Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.1']} DrugCentral uuid:3b704cec-7972-11ec-93d9-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:5322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ravulizumab is antibody binding of Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.357']} DrugCentral uuid:3b7079e2-7972-11ec-93d9-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tagraxofusp is binding agent of Membrane receptor (Interleukin-3 receptor) DrugCentral uuid:3b7079e2-7972-11ec-93d9-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tagraxofusp is binding agent of Membrane receptor (Interleukin-3 receptor) DrugCentral uuid:3b70a930-7972-11ec-93d9-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:3b70d9d2-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:3b70d9d2-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:3b70d9d2-7972-11ec-93d9-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:3b7125ea-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:3b7125ea-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:3b7125ea-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:3b716eba-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:3b716eba-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:3b716eba-7972-11ec-93d9-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:3b71b032-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.088']} DrugCentral uuid:3b71da30-7972-11ec-93d9-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.432']} DrugCentral uuid:3b720352-7972-11ec-93d9-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.848']} DrugCentral uuid:3b722d00-7972-11ec-93d9-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.125']} DrugCentral uuid:3b72571c-7972-11ec-93d9-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3']} DrugCentral uuid:3b728016-7972-11ec-93d9-0242ac110002 UniProtKB:O95136 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:3b72a91a-7972-11ec-93d9-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.409']} DrugCentral uuid:3b72d386-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.009']} DrugCentral uuid:3b72fc6c-7972-11ec-93d9-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:3b732566-7972-11ec-93d9-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:3b734e74-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.434']} DrugCentral uuid:3b7377f0-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:3b73a108-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.921']} DrugCentral uuid:3b73ca3e-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.602']} DrugCentral uuid:3b73f428-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.244']} DrugCentral uuid:3b741dc2-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3b7446da-7972-11ec-93d9-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b746fe8-7972-11ec-93d9-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3b749a68-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Z1L0 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3b74c3da-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.337']} DrugCentral uuid:3b74ece8-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:3b751632-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:3b753fcc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.02']} DrugCentral uuid:3b7568bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Adrenocorticotropic hormone receptor) DrugCentral uuid:3b758dba-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:3b75b7ea-7972-11ec-93d9-0242ac110002 UniProtKB:O14980 biolink:molecularly_interacts_with DrugCentral:5330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selinexor is inhibitor of Nuclear other (Exportin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:3b75e1c0-7972-11ec-93d9-0242ac110002 UniProtKB:P60880 biolink:molecularly_interacts_with DrugCentral:5331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prabotulinumtoxinA is blocker of Cytosolic other (Synaptosomal-associated protein 25) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b762554-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3b769fb6-7972-11ec-93d9-0242ac110002 UniProtKB:P40259 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is antibody binding of Tumour-associated antigen (B-cell antigen receptor complex-associated protein beta chain) DrugCentral uuid:3b76c496-7972-11ec-93d9-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is antagonist of Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:3b76edc2-7972-11ec-93d9-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is antagonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:3b771306-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is inhibitor of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.187']} DrugCentral uuid:3b773c1e-7972-11ec-93d9-0242ac110002 UniProtKB:P02656 biolink:molecularly_interacts_with DrugCentral:5335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 volanesorsen is antisense inhibitor of RNA (apolipoprotein C-III (apoC-III) mRNA) DrugCentral uuid:3b77623e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risankizumab is inhibitor of Cytokine (Interleukin-23 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:3b778f5c-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropeginterferon alfa-2b is binding agent of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b778f5c-7972-11ec-93d9-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropeginterferon alfa-2b is binding agent of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:3b77bfb8-7972-11ec-93d9-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:5339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:3b77e8da-7972-11ec-93d9-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:5339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.444']} DrugCentral uuid:3b78126a-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3b783c40-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3b786558-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3b788e5c-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3b78b774-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3b78e0d2-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:3b7909cc-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:3b7933fc-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:3b795d00-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3b7986a4-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3b79af9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3b79d8a2-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b7a0192-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3b7a2cd0-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3b7a55ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:3b7a7ee2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3b7aa7e6-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3b7ad162-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b7afa84-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:3b7b23c4-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3b7b4d7c-7972-11ec-93d9-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:3b7b7694-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:3b7b9f8e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:3b7bc8a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:3b7bf34e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3b7c1c8e-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3b7c459c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:3b7c6eb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3b7c9826-7972-11ec-93d9-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3b7cc13e-7972-11ec-93d9-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3b7cea56-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3b7d135a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3b7d3f38-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b7d6846-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3b7d9154-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3b7dbb52-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b7de4e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3b7e0dfa-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.796']} DrugCentral uuid:3b7e3712-7972-11ec-93d9-0242ac110002 UniProtKB:Q8RL90 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3b7e6066-7972-11ec-93d9-0242ac110002 UniProtKB:Q2PUH3 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:3b7e899c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9X5A7 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3b7eb32c-7972-11ec-93d9-0242ac110002 UniProtKB:Q93LQ9 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3b7edc3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q93DC4 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:3b7f05e8-7972-11ec-93d9-0242ac110002 UniProtKB:B1PL86 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3b7f2f0a-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3b7f57fa-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:3b7f80fe-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:3b7fac64-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:3b7fd5c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3b7ffed0-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.56']} DrugCentral uuid:3b8027de-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:3b80515a-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.88']} DrugCentral uuid:3b807a36-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3b80a344-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:3b80ccfc-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3b80f60a-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:3b811f04-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3b81490c-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3b8173f0-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:3b819d08-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.67']} DrugCentral uuid:3b81c60c-7972-11ec-93d9-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:3b81ef88-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3b821918-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3b824230-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:3b826b5c-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3b829460-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:3b82be22-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3b82e730-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:3b831034-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3b833a1e-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3b8364ee-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:3b838dfc-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:3b83b7a0-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b83e0ea-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:3b8409ee-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3b8432fc-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:3b845c00-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3b8485c2-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:3b84aec6-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:3b84d7de-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b8500e2-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:3b852cca-7972-11ec-93d9-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3b8556be-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:3b857fea-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3b85a952-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3b85d260-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3b85fb64-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b862468-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3b864df8-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3b8676fc-7972-11ec-93d9-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3b86a00a-7972-11ec-93d9-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3b86c922-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3b86f456-7972-11ec-93d9-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3b871dd2-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3b8746d6-7972-11ec-93d9-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:3b876fda-7972-11ec-93d9-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3b87994c-7972-11ec-93d9-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:3b87c264-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3b87eb72-7972-11ec-93d9-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3b881480-7972-11ec-93d9-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:3b883e4c-7972-11ec-93d9-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3b886764-7972-11ec-93d9-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3b889068-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b88ba34-7972-11ec-93d9-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3b88e360-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:3b890c64-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3b89355e-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3b8960c4-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3b8989c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3b89b2e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3b89dbe4-7972-11ec-93d9-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:3b8a05a6-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3b8a2eb4-7972-11ec-93d9-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:3b8a57e0-7972-11ec-93d9-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:3b8a815c-7972-11ec-93d9-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:3b8aad58-7972-11ec-93d9-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b8ad65c-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3b8aff74-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3b8b28e6-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b8b51ea-7972-11ec-93d9-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3b8b7aee-7972-11ec-93d9-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:3b8ba3e8-7972-11ec-93d9-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b8bcd96-7972-11ec-93d9-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3b8bf6a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3b8c1fb2-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:3b8c48c0-7972-11ec-93d9-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:3b8c732c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3b8c9c30-7972-11ec-93d9-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:3b8cc53e-7972-11ec-93d9-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3b8cee4c-7972-11ec-93d9-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3b8d17be-7972-11ec-93d9-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3b8d40c2-7972-11ec-93d9-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:3b8d6ad4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3b8d93ce-7972-11ec-93d9-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:3b8dbd90-7972-11ec-93d9-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:3b8de694-7972-11ec-93d9-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3b8e0fa2-7972-11ec-93d9-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3b8e3964-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:3b8e627c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3b8e8b80-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3b8eb498-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3b8eddf6-7972-11ec-93d9-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:3b8f0704-7972-11ec-93d9-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3b8f3008-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3b8f5916-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:3b8f83e6-7972-11ec-93d9-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:3b8facf4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.5']} DrugCentral uuid:3b8fd620-7972-11ec-93d9-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:3b8fff2e-7972-11ec-93d9-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3b902b84-7972-11ec-93d9-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3b90550a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3b907e0e-7972-11ec-93d9-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:3b90a7b2-7972-11ec-93d9-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3b90d0c0-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3b90f9ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:3b9122c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b914c76-7972-11ec-93d9-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:3b91767e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:3b91a018-7972-11ec-93d9-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3b91c926-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3b91f338-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b921c46-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:3b92454a-7972-11ec-93d9-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:3b926e4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:3b9297c0-7972-11ec-93d9-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3b92c0c4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b92e9d2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3b9312ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3b933ce8-7972-11ec-93d9-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3b9365e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3b938efa-7972-11ec-93d9-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:3b93b952-7972-11ec-93d9-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3b93e4ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3b940df8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3b943706-7972-11ec-93d9-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3b94606e-7972-11ec-93d9-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3b9489a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:3b94b2a8-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b94dbb6-7972-11ec-93d9-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3b950564-7972-11ec-93d9-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3b952e86-7972-11ec-93d9-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:3b955794-7972-11ec-93d9-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b9582aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3b95acd0-7972-11ec-93d9-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3b95d5f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3b95ff0a-7972-11ec-93d9-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3b962886-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b965194-7972-11ec-93d9-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b967ab6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:3b96a3b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3b96cd72-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:3b96f68a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3b971fa2-7972-11ec-93d9-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3b9748b0-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:3b9772f4-7972-11ec-93d9-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:3b979bf8-7972-11ec-93d9-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3b97c51a-7972-11ec-93d9-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:3b97ee28-7972-11ec-93d9-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:3b9817ae-7972-11ec-93d9-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3b9840bc-7972-11ec-93d9-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:3b986a4c-7972-11ec-93d9-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3b9893dc-7972-11ec-93d9-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3b98bd08-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3b98e616-7972-11ec-93d9-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3b990f24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3b9938e6-7972-11ec-93d9-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3b996208-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3b998bfc-7972-11ec-93d9-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3b99b50a-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3b99de7c-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3b9a0776-7972-11ec-93d9-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3b9a30b6-7972-11ec-93d9-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b9a59ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:3b9a837c-7972-11ec-93d9-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3b9aac94-7972-11ec-93d9-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3b9ad5a2-7972-11ec-93d9-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:3b9afec4-7972-11ec-93d9-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3b9b2a20-7972-11ec-93d9-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:3b9b532e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3b9b7c32-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3b9ba6f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3b9bd01a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3b9bf932-7972-11ec-93d9-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3b9c2236-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3b9c4be4-7972-11ec-93d9-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:3b9c74de-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:3b9c9df6-7972-11ec-93d9-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:3b9cc6f0-7972-11ec-93d9-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3b9cf260-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3b9d1b82-7972-11ec-93d9-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b9d449a-7972-11ec-93d9-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3b9d6da8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:3b9d9832-7972-11ec-93d9-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:3b9dc12c-7972-11ec-93d9-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3b9dea3a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3b9e13fc-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3b9e3d00-7972-11ec-93d9-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3b9e6604-7972-11ec-93d9-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3b9e8f26-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3b9eb992-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3b9ee2aa-7972-11ec-93d9-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:3b9f0bb8-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:3b9f3548-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3b9f5e88-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3b9f8796-7972-11ec-93d9-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3b9fb086-7972-11ec-93d9-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:3b9fd994-7972-11ec-93d9-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:3ba00342-7972-11ec-93d9-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:3ba02c50-7972-11ec-93d9-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:3ba05554-7972-11ec-93d9-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3ba07e6c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:3ba0aa54-7972-11ec-93d9-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3ba0d380-7972-11ec-93d9-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3ba0fc7a-7972-11ec-93d9-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3ba12628-7972-11ec-93d9-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3ba14f22-7972-11ec-93d9-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:3ba1783a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:3ba1a31e-7972-11ec-93d9-0242ac110002 UniProtKB:Q6P3R8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3ba1ccd6-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD19 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:3ba1f5e4-7972-11ec-93d9-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3ba21ee8-7972-11ec-93d9-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3ba247ec-7972-11ec-93d9-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3ba271a4-7972-11ec-93d9-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3ba29aa8-7972-11ec-93d9-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:3ba2c3b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:3ba2ecba-7972-11ec-93d9-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3ba3169a-7972-11ec-93d9-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:3ba33f9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H4B4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3ba368b6-7972-11ec-93d9-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3ba39232-7972-11ec-93d9-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:3ba3bb54-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:3ba3e46c-7972-11ec-93d9-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:3ba40d98-7972-11ec-93d9-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3ba43818-7972-11ec-93d9-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3ba46162-7972-11ec-93d9-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:3ba48a84-7972-11ec-93d9-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:3ba4b3a6-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:3ba4dd54-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:3ba50662-7972-11ec-93d9-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:3ba52f66-7972-11ec-93d9-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:3ba55892-7972-11ec-93d9-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3ba58218-7972-11ec-93d9-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3ba5ac20-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.05']} DrugCentral uuid:3ba5d524-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:3ba5feb4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3ba628e4-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:3ba65206-7972-11ec-93d9-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3ba67b0a-7972-11ec-93d9-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3ba6a4e0-7972-11ec-93d9-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3ba6cde4-7972-11ec-93d9-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3ba6f6f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:3ba71ff6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3ba74968-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3ba77262-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3ba79b66-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3ba7c5d2-7972-11ec-93d9-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:3ba7f070-7972-11ec-93d9-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:3ba81988-7972-11ec-93d9-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:3ba84296-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:3ba86b90-7972-11ec-93d9-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3ba89548-7972-11ec-93d9-0242ac110002 UniProtKB:Q15208 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3ba8be56-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:3ba8e764-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:3ba910c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:3ba939da-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3ba962d4-7972-11ec-93d9-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3ba98be2-7972-11ec-93d9-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:3ba9b6ee-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3ba9e006-7972-11ec-93d9-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:3baa090a-7972-11ec-93d9-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3baa3204-7972-11ec-93d9-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:3baa5b9e-7972-11ec-93d9-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3baa84ac-7972-11ec-93d9-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3baaada6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:3baad6be-7972-11ec-93d9-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:3bab0044-7972-11ec-93d9-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3bab295c-7972-11ec-93d9-0242ac110002 UniProtKB:O76039 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase-like 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:3bab526a-7972-11ec-93d9-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3bab7ba0-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3baba7f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3babd10e-7972-11ec-93d9-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:3babfa1c-7972-11ec-93d9-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3bac23de-7972-11ec-93d9-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:3bac4cce-7972-11ec-93d9-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:3bac75dc-7972-11ec-93d9-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:3bac9eea-7972-11ec-93d9-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3bacc8f2-7972-11ec-93d9-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:3bacf1e2-7972-11ec-93d9-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3bad1afa-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQI3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:3bad43ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3bad6f96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NRH2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SNF-related serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:3bad9bb0-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3badc6c6-7972-11ec-93d9-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3badefd4-7972-11ec-93d9-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3bae1982-7972-11ec-93d9-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:3bae429a-7972-11ec-93d9-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:3bae6bb2-7972-11ec-93d9-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:3bae952e-7972-11ec-93d9-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:3baebe3c-7972-11ec-93d9-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.79']} DrugCentral uuid:3baee768-7972-11ec-93d9-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:3baf1076-7972-11ec-93d9-0242ac110002 UniProtKB:Q9HC98 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:3baf3a38-7972-11ec-93d9-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:3baf635a-7972-11ec-93d9-0242ac110002 UniProtKB:P51957 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:3baf8c72-7972-11ec-93d9-0242ac110002 UniProtKB:Q58F21 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Unclassified (Bromodomain testis-specific protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3bafb580-7972-11ec-93d9-0242ac110002 UniProtKB:Q96PY6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3bafdf2e-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:3bb00850-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:3bb0314a-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3bb05a62-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:3bb083e8-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3bb0acf6-7972-11ec-93d9-0242ac110002 UniProtKB:P26433 biolink:molecularly_interacts_with DrugCentral:5349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenapanor targets Transporter (Sodium/hydrogen exchanger 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:3bb0d618-7972-11ec-93d9-0242ac110002 UniProtKB:P48764 biolink:molecularly_interacts_with DrugCentral:5349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenapanor is inhibitor of Transporter (Sodium/hydrogen exchanger 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.06']} DrugCentral uuid:3bb10016-7972-11ec-93d9-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3bb12974-7972-11ec-93d9-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:3bb1526e-7972-11ec-93d9-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:3bb17b7c-7972-11ec-93d9-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:5351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasmiditan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:3bb1a642-7972-11ec-93d9-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3bb1cf5a-7972-11ec-93d9-0242ac110002 UniProtKB:Q07806 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3bb1f868-7972-11ec-93d9-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3bb22248-7972-11ec-93d9-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3bb24bec-7972-11ec-93d9-0242ac110002 UniProtKB:G1C775 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:3bb2750e-7972-11ec-93d9-0242ac110002 UniProtKB:A6T4V3 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:3bb29e3a-7972-11ec-93d9-0242ac110002 UniProtKB:H4I819 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase MrdA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3bb2c75c-7972-11ec-93d9-0242ac110002 UniProtKB:A0A0W8ASI8 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase MrdA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:3bb2f164-7972-11ec-93d9-0242ac110002 UniProtKB:A6T4M7 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3bb31a7c-7972-11ec-93d9-0242ac110002 UniProtKB:G3XD46 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:3bb34394-7972-11ec-93d9-0242ac110002 UniProtKB:D0CCM7 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:3bb36cc0-7972-11ec-93d9-0242ac110002 UniProtKB:A0A5E6DR09 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:3bb3963c-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanubrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:3bb3bf40-7972-11ec-93d9-0242ac110002 UniProtKB:P13196 biolink:molecularly_interacts_with DrugCentral:5354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 givosiran is antisense inhibitor of RNA (aminolevulinate synthase1 (ALAS1) mRNA) DrugCentral uuid:3bb3e542-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:3bb40f18-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:3bb43844-7972-11ec-93d9-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:3bb4615c-7972-11ec-93d9-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:3bb48a74-7972-11ec-93d9-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:3bb4b530-7972-11ec-93d9-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:3bb4de70-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:3bb507ce-7972-11ec-93d9-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Transporter (hemoglobin subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:3bb530d2-7972-11ec-93d9-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 golodirsen is antisense inhibitor of RNA (exon 53 of dystrophin pre-mRNA) DrugCentral uuid:3bb5562a-7972-11ec-93d9-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:3bb57f42-7972-11ec-93d9-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:3bb5a954-7972-11ec-93d9-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:3bb5d29e-7972-11ec-93d9-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:3bb5fc4c-7972-11ec-93d9-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:3bb62564-7972-11ec-93d9-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:3bb64e90-7972-11ec-93d9-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:3bb677b2-7972-11ec-93d9-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:3bb6a552-7972-11ec-93d9-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:3bb6cec4-7972-11ec-93d9-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:3bb6f7c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q99572 biolink:molecularly_interacts_with DrugCentral:5359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brilliant Blue G is antagonist of Ion channel (P2X purinoceptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3bb72126-7972-11ec-93d9-0242ac110002 UniProtKB:P37840 biolink:molecularly_interacts_with DrugCentral:5359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brilliant Blue G targets Transporter (Alpha-synuclein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3bb74a2a-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3bb7734c-7972-11ec-93d9-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant is antagonist of GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3bb79c78-7972-11ec-93d9-0242ac110002 UniProtKB:O43614 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant is antagonist of GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3bb7c680-7972-11ec-93d9-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubrogepant is antagonist of GPCR (Calcitonin gene-related peptide type 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.2']} DrugCentral uuid:3bb7efa2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9BQB4 biolink:molecularly_interacts_with DrugCentral:5362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romosozumab is binding agent of Glycoprotein (Sclerostin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.7']} DrugCentral uuid:3bb818d8-7972-11ec-93d9-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brolucizumab is inhibitor of Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3bb8420e-7972-11ec-93d9-0242ac110002 UniProtKB:O95390 biolink:molecularly_interacts_with DrugCentral:5364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luspatercept is binding agent of Cytokine (Growth/differentiation factor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.13']} DrugCentral uuid:3bb86cca-7972-11ec-93d9-0242ac110002 UniProtKB:O14793 biolink:molecularly_interacts_with DrugCentral:5364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luspatercept is binding agent of Cytokine (Growth/differentiation factor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.69']} DrugCentral uuid:3bb895ec-7972-11ec-93d9-0242ac110002 UniProtKB:P16109 biolink:molecularly_interacts_with DrugCentral:5365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizanlizumab is inhibitor of Adhesion (P-selectin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb8ddae-7972-11ec-93d9-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:3bb9590a-7972-11ec-93d9-0242ac110002 UniProtKB:Q96NY8 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Nectin-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.24']} DrugCentral uuid:3bb98236-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab deruxtecan is binding agent of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:3bb9acca-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:5367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab deruxtecan is inhibitor of Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:3bb9d5ce-7972-11ec-93d9-0242ac110002 UniProtKB:P60880 biolink:molecularly_interacts_with DrugCentral:5368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 botulinum toxin type A is blocker of Cytosolic other (Synaptosomal-associated protein 25) DrugCentral uuid:3bb9faa4-7972-11ec-93d9-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:3bba23b2-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3bba4dce-7972-11ec-93d9-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3bba76e6-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:3bba9fea-7972-11ec-93d9-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elexacaftor targets Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:3bbac952-7972-11ec-93d9-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3bbaf27e-7972-11ec-93d9-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine is inhibitor of Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) DrugCentral uuid:3bbb174a-7972-11ec-93d9-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine is inhibitor of Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) DrugCentral uuid:3bbb3cb6-7972-11ec-93d9-0242ac110002 UniProtKB:P0DTD1 biolink:molecularly_interacts_with DrugCentral:5376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remdesivir is inhibitor of Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3bbb666e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefuparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3bbb8f68-7972-11ec-93d9-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefuparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:3bbbb880-7972-11ec-93d9-0242ac110002 UniProtKB:P05532 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:3bbbe198-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.57']} DrugCentral uuid:3bbc0c86-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:3bbc35a8-7972-11ec-93d9-0242ac110002 UniProtKB:O75530 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat targets Unclassified (Polycomb protein EED) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3bbc5ec0-7972-11ec-93d9-0242ac110002 UniProtKB:Q92800 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat is inhibitor of Enzyme (Histone-lysine N-methyltransferase EZH1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:3bbc87ce-7972-11ec-93d9-0242ac110002 UniProtKB:Q15910 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat is inhibitor of Enzyme (Histone-lysine N-methyltransferase EZH2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:3bbcb154-7972-11ec-93d9-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimegepant is antagonist of GPCR (Calcitonin gene-related peptide type 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.56']} DrugCentral uuid:3bbcda80-7972-11ec-93d9-0242ac110002 UniProtKB:P53396 biolink:molecularly_interacts_with DrugCentral:5382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bempedoic acid is inhibitor of Enzyme (ATP-citrate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:3bbd04d8-7972-11ec-93d9-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3bbd2dd2-7972-11ec-93d9-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:3bbd5794-7972-11ec-93d9-0242ac110002 UniProtKB:O95136 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:3bbd8084-7972-11ec-93d9-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:3bbda97e-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:3bbdd35e-7972-11ec-93d9-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:3bbdfca8-7972-11ec-93d9-0242ac110002 UniProtKB:P15539 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:3bbe25a2-7972-11ec-93d9-0242ac110002 UniProtKB:P15393 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:3bbe4e88-7972-11ec-93d9-0242ac110002 UniProtKB:P30099 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:3bbe77c8-7972-11ec-93d9-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:3bbea0cc-7972-11ec-93d9-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:3bbec9da-7972-11ec-93d9-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:5385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isatuximab is binding agent of Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3bbef41e-7972-11ec-93d9-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptinezumab is binding agent of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.82']} DrugCentral uuid:3bbf1dea-7972-11ec-93d9-0242ac110002 UniProtKB:P10092 biolink:molecularly_interacts_with DrugCentral:5386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptinezumab is binding agent of GPCR (Calcitonin gene-related peptide 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.24']} DrugCentral uuid:3bbf470c-7972-11ec-93d9-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teprotumumab is antagonist of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3bbf701a-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:3bbf99a0-7972-11ec-93d9-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3bbfc4ac-7972-11ec-93d9-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:3bbfedb0-7972-11ec-93d9-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:3bc016be-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:3bc0440e-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (ERBB2/ERBB3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:3bc0440e-7972-11ec-93d9-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (ERBB2/ERBB3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:3bc0791a-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:3bc0a250-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3bc0cc4e-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:3bc0f5fc-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:3bc11f00-7972-11ec-93d9-0242ac110002 UniProtKB:P55899 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is antibody binding of Membrane receptor (IgG receptor FcRn large subunit p51) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.71']} DrugCentral uuid:3bc14836-7972-11ec-93d9-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is binding agent of Enzyme (DNA topoisomerase 1) DrugCentral uuid:3bc16d16-7972-11ec-93d9-0242ac110002 UniProtKB:P09758 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is antibody binding of Tumour-associated antigen (Tumor-associated calcium signal transducer 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.58']} DrugCentral uuid:3bc197f0-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capmatinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.88']} DrugCentral uuid:3bc1c11c-7972-11ec-93d9-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selpercatinib is inhibitor of Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:3bc1ea34-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selpercatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:3bc21342-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3bc23cbe-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:3bc265cc-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:3bc28eee-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:3bc2b8c4-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3bc2e1d2-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:3bc30afe-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:5395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoroestradiol F 18 is binding agent of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.07']} DrugCentral uuid:3bc33420-7972-11ec-93d9-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:5396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flortaucipir F 18 is binding agent of Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:3bc35e96-7972-11ec-93d9-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inebilizumab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3bc387c2-7972-11ec-93d9-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inebilizumab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.8']} DrugCentral uuid:3bc3b88c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3bc3b88c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3bc3b88c-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:3bc40274-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3bc40274-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3bc40274-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:3bc44c84-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3bc44c84-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3bc44c84-7972-11ec-93d9-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:3bc49766-7972-11ec-93d9-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:3bc49766-7972-11ec-93d9-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:3bc49766-7972-11ec-93d9-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:3bc4ef9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3bc4ef9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3bc4ef9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3bc4ef9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3bc4ef9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3bc4ef9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3bc4ef9a-7972-11ec-93d9-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:3bc5642a-7972-11ec-93d9-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:5401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostemsavir is inhibitor of Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.08']} DrugCentral uuid:3bc58d56-7972-11ec-93d9-0242ac110002 UniProtKB:P32320 biolink:molecularly_interacts_with DrugCentral:5402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inqovi is inhibitor of Enzyme (Cytidine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:3bc5b65a-7972-11ec-93d9-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3bc5dfc2-7972-11ec-93d9-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3bc608d0-7972-11ec-93d9-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:3bc631e8-7972-11ec-93d9-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3bc65b5a-7972-11ec-93d9-0242ac110002 UniProtKB:P51685 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3bc6847c-7972-11ec-93d9-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafasitamab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.39']} DrugCentral uuid:3bc6adbc-7972-11ec-93d9-0242ac110002 UniProtKB:P55899 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (IgG receptor FcRn large subunit p51) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:3bc6d6de-7972-11ec-93d9-0242ac110002 UniProtKB:P12314 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (High affinity immunoglobulin gamma Fc receptor I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:3bc7017c-7972-11ec-93d9-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:3bc72bde-7972-11ec-93d9-0242ac110002 UniProtKB:Q02223 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Tumour-associated antigen (Tumor necrosis factor receptor superfamily member 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:3bc754f6-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3bc77de6-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3bc7a762-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:3bc7d05c-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:3bc7f96a-7972-11ec-93d9-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:3bc8226e-7972-11ec-93d9-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3bc84c30-7972-11ec-93d9-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine is agonist of GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:3bc87548-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3bc89e88-7972-11ec-93d9-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viltolarsen is binding agent of RNA (exon 53 of dystrophin pre-mRNA) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:3bc8cca0-7972-11ec-93d9-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 satralizumab is antagonist of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3bc8cca0-7972-11ec-93d9-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 satralizumab is antagonist of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3bc9053a-7972-11ec-93d9-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clascoterone is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3bc92e3e-7972-11ec-93d9-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copper dotatate Cu-64 is binding agent of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.69']} DrugCentral uuid:3bc95896-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:3bc98208-7972-11ec-93d9-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3bc9ab2a-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3bc9d424-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:3bc9fd3c-7972-11ec-93d9-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3bca26f4-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3bca4ff8-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:3bca7906-7972-11ec-93d9-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:3bcaa30e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:3bcacc58-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:3bcaf688-7972-11ec-93d9-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somapacitan targets GPCR (Growth hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.04']} DrugCentral uuid:3bcb1faa-7972-11ec-93d9-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Cytosolic other (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3bcb493a-7972-11ec-93d9-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:3bcb722a-7972-11ec-93d9-0242ac110002 UniProtKB:P01111 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase NRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:3bcb9b38-7972-11ec-93d9-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3bcbc432-7972-11ec-93d9-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:3bcbf1f0-7972-11ec-93d9-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3bcbf1f0-7972-11ec-93d9-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:3bcc2724-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UJM8 biolink:molecularly_interacts_with DrugCentral:5415 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumasiran is antisense inhibitor of RNA (Hydroxyacid oxidase 1 (HAO1) mRNA) DrugCentral uuid:3bcc4be6-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3bcc759e-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3bcc9f2e-7972-11ec-93d9-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:3bccc850-7972-11ec-93d9-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:3bccf186-7972-11ec-93d9-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:3bcd1b0c-7972-11ec-93d9-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:3bcd442e-7972-11ec-93d9-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.68']} DrugCentral uuid:3bcd6d64-7972-11ec-93d9-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:5417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bulevirtide is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:3bcda20c-7972-11ec-93d9-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:3bcda20c-7972-11ec-93d9-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:3bcda20c-7972-11ec-93d9-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:3bcda20c-7972-11ec-93d9-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:3bcde7da-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:3bce10de-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3bce39ec-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:3bce6426-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3bce8d2a-7972-11ec-93d9-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:3bceb732-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:3bcee162-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:3bcf0ade-7972-11ec-93d9-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:3bcf3400-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:3bcf5d0e-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:3bcf86e4-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:3bcfaffc-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:3bcfd946-7972-11ec-93d9-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3bd00236-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Enzyme (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3bd02c7a-7972-11ec-93d9-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:3bd0557e-7972-11ec-93d9-0242ac110002 UniProtKB:Q8N543 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Prolyl 3-hydroxylase OGFOD1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3bd07e96-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:3bd0a79a-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:3bd0d116-7972-11ec-93d9-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.93']} DrugCentral uuid:3bd0fa24-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:3bd12364-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.46']} DrugCentral uuid:3bd14c90-7972-11ec-93d9-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:3bd17652-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:3bd19f56-7972-11ec-93d9-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:5422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 borofalan (10B) is substrate of Transporter (L-type amino acid transporter 1) DrugCentral uuid:3bd1c4a4-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3bd1eeac-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3bd21abc-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3bd24456-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:3bd26d6e-7972-11ec-93d9-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:3bd296fe-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:3bd2c138-7972-11ec-93d9-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:3bd2ea78-7972-11ec-93d9-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:3bd3139a-7972-11ec-93d9-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3bd33d70-7972-11ec-93d9-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:3bd36692-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:5424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tepotinib is inhibitor of Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:3bd38fb4-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tepotinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:3bd3b8ea-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3bd3e4dc-7972-11ec-93d9-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:3bd40e80-7972-11ec-93d9-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:3bd43784-7972-11ec-93d9-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:3bd460b0-7972-11ec-93d9-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:3bd48a18-7972-11ec-93d9-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:3bd4b344-7972-11ec-93d9-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:3bd4dd88-7972-11ec-93d9-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:3bd50772-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:3bd530b2-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:3bd559ca-7972-11ec-93d9-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3bd582d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:3bd5ae02-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:3bd5da8a-7972-11ec-93d9-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:5428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofpironium bromide is inhibitor of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:3bd6005a-7972-11ec-93d9-0242ac110002 UniProtKB:P07288 biolink:molecularly_interacts_with DrugCentral:5429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallium (68Ga) gozetotide is binding agent of Surface antigen (Prostate-specific antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:3bd6299a-7972-11ec-93d9-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:5430 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 berotralstat is inhibitor of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:3bd65316-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:3bd67c2e-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3bd6a546-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:3bd6cf08-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:3bd6f8ca-7972-11ec-93d9-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:3bd721c4-7972-11ec-93d9-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:3bd74af0-7972-11ec-93d9-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:3bd77516-7972-11ec-93d9-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ansuvimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:3bd79ea6-7972-11ec-93d9-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 margetuximab is antagonist of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.55']} DrugCentral uuid:3bd7c7dc-7972-11ec-93d9-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 margetuximab is antagonist of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:3bd7f13a-7972-11ec-93d9-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atoltivimab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:3bd81aca-7972-11ec-93d9-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atoltivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:3bd84400-7972-11ec-93d9-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maftivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:3bd86d54-7972-11ec-93d9-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 odesivimab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:3bd8968a-7972-11ec-93d9-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 odesivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:3bd8c074-7972-11ec-93d9-0242ac110002 UniProtKB:P20595 biolink:molecularly_interacts_with DrugCentral:5439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vericiguat is activator of Enzyme (Guanylate cyclase soluble subunit beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:3bd8e98c-7972-11ec-93d9-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:5439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vericiguat is activator of Enzyme (Guanylate cyclase soluble subunit beta-1) DrugCentral uuid:3bd90e4e-7972-11ec-93d9-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3bd9375c-7972-11ec-93d9-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir targets Unclassified (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3bd96204-7972-11ec-93d9-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:3bd98b08-7972-11ec-93d9-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:3bd9b434-7972-11ec-93d9-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:3bd9dd6a-7972-11ec-93d9-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:3bda079a-7972-11ec-93d9-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.21']} DrugCentral uuid:3bda30bc-7972-11ec-93d9-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3bda59ca-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:3bda8396-7972-11ec-93d9-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:3bdaad94-7972-11ec-93d9-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3bdad7d8-7972-11ec-93d9-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:3bdb00f0-7972-11ec-93d9-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:3bdb2b5c-7972-11ec-93d9-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:3bdb5488-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:3bdb7daa-7972-11ec-93d9-0242ac110002 UniProtKB:Q6ZWH5 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Serine/threonine-protein kinase Nek10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.57']} DrugCentral uuid:3bdba6d6-7972-11ec-93d9-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:3bdbd070-7972-11ec-93d9-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:3bdbf97e-7972-11ec-93d9-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casimersen is antisense inhibitor of RNA (exon 53 of dystrophin pre-mRNA) DrugCentral uuid:3bdc1e40-7972-11ec-93d9-0242ac110002 UniProtKB:Q9NZB8 biolink:molecularly_interacts_with DrugCentral:5444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosdenopterin targets Enzyme (Molybdenum cofactor biosynthesis protein 1) DrugCentral uuid:3bdc42f8-7972-11ec-93d9-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:3bdc6cb0-7972-11ec-93d9-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3bdc95b4-7972-11ec-93d9-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:3bdcbecc-7972-11ec-93d9-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:3bdce7da-7972-11ec-93d9-0242ac110002 UniProtKB:P47871 biolink:molecularly_interacts_with DrugCentral:5447 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasiglucagon is agonist of GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:3bdd1494-7972-11ec-93d9-0242ac110002 UniProtKB:Q9Y5C1 biolink:molecularly_interacts_with DrugCentral:5449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evinacumab is inhibitor of Secreted (Angiopoietin-related protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:3bdd3e10-7972-11ec-93d9-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:5450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estetrol is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:3bdd6728-7972-11ec-93d9-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:5450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estetrol is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:3bdd90c2-7972-11ec-93d9-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:5451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dostarlimab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:3bddb9c6-7972-11ec-93d9-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loncastuximab tesirine is antibody binding of Surface antigen (B-lymphocyte antigen CD19) DrugCentral uuid:3bddde92-7972-11ec-93d9-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5453 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bamlanivimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.15']} DrugCentral uuid:3bde078c-7972-11ec-93d9-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etesevimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:3bde314e-7972-11ec-93d9-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casirivimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.34']} DrugCentral uuid:3bde5a98-7972-11ec-93d9-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imdevimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.33']} DrugCentral uuid:3bde83ce-7972-11ec-93d9-0242ac110002 UniProtKB:P01024 biolink:molecularly_interacts_with DrugCentral:5457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegcetacoplan is inhibitor of Unclassified (Complement C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:3bdeae44-7972-11ec-93d9-0242ac110002 UniProtKB:Q04609 biolink:molecularly_interacts_with DrugCentral:5458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piflufolastat F-18 is binding agent of Enzyme (Glutamate carboxypeptidase 2) DrugCentral uuid:3bded4aa-7972-11ec-93d9-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3bdefd90-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3bdf268a-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3bdf4f70-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:3bdf78b0-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3bdfa1a0-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3bdfcaae-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3bdff38a-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3be01cf2-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3be045d8-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3be06ef0-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3be097d6-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3be0c30a-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3be0ec04-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3be11512-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3be13eac-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3be167a6-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3be190c8-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:3be1b9d6-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3be1e33e-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3be20c4c-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3be23550-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3be25e54-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3be2897e-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3be2b372-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3be2dc6c-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3be30566-7972-11ec-93d9-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:3be32f46-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3be35836-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:3be38144-7972-11ec-93d9-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:3be3aad4-7972-11ec-93d9-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3be3d3d8-7972-11ec-93d9-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:3be3fcc8-7972-11ec-93d9-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3be425ea-7972-11ec-93d9-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:3be4507e-7972-11ec-93d9-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:3be4796e-7972-11ec-93d9-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:3be4a272-7972-11ec-93d9-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:3be4cb62-7972-11ec-93d9-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3be4f4fc-7972-11ec-93d9-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3be51e00-7972-11ec-93d9-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3be546fa-7972-11ec-93d9-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:3be56ffe-7972-11ec-93d9-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:3be599a2-7972-11ec-93d9-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:3be5c2a6-7972-11ec-93d9-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:3be5ebb4-7972-11ec-93d9-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:3be614cc-7972-11ec-93d9-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:3be63eb6-7972-11ec-93d9-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:3be667a6-7972-11ec-93d9-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:3be691ae-7972-11ec-93d9-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:3be6bc4c-7972-11ec-93d9-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:3be6e564-7972-11ec-93d9-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:3be70e72-7972-11ec-93d9-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:3be73780-7972-11ec-93d9-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:3be76138-7972-11ec-93d9-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:3be78a64-7972-11ec-93d9-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:3be7b37c-7972-11ec-93d9-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:3be7dc8a-7972-11ec-93d9-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) DrugCentral uuid:3be802e6-7972-11ec-93d9-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) DrugCentral uuid:3be827b2-7972-11ec-93d9-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) DrugCentral uuid:3be84c74-7972-11ec-93d9-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) DrugCentral uuid:3be87136-7972-11ec-93d9-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.28']} DrugCentral uuid:3be89ad0-7972-11ec-93d9-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is partial agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:3be8c406-7972-11ec-93d9-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is partial agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:3be8ed3c-7972-11ec-93d9-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotorasib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:3be91654-7972-11ec-93d9-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:3be94098-7972-11ec-93d9-0242ac110002 UniProtKB:Q6FTN8 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (1,3-Beta-D-glucan-UDP glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:3be969b0-7972-11ec-93d9-0242ac110002 UniProtKB:P87204 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (1,3-Beta-D-glucan-UDP glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.97']} DrugCentral